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Get operating grants for nonprofits covering essential expenses, staffing, program delivery, and organizational sustainability.
32,000+
Available grants
$9.00B
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$6K
Median grant
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Sickle Cell Disease Pilot Program 2027
The SCD Pilot Program was established under New Jersey legislation (A4052) with funding appropriated for a three-year pilot. Beginning its third year (September-June) as a noncompeting continuation, the program supports Federally Qualified Health Centers (FQHCs) in select municipalities in delivering coordinated, comprehensive care for individuals living with SCD. The program’s purpose is to improve health outcomes and quality of life by providing an integrated model that combines medical, behavioral, social, and educational services. It emphasizes strong communication pathways with external providers and ongoing education and outreach to patients, caregivers, staff, and the broader community. The New Jersey Department of Health (NJDOH), in collaboration with the New Jersey Department of Human Services (NJDHS), oversees this initiative to address the complex healthcare needs of New Jerseyans affected by SCD.
SCD is a lifelong, inherited condition with several common types, including:
HbSS (Sickle Cell Anemia): The most severe and common form, caused by inheriting a sickle cell gene (“S”) from each parent. It predominantly affects individuals of African ancestry but can also impact people of Southern European, Middle Eastern, or Asian Indian descent.
HbSC (Sickle Cell Hemoglobin C Disease): A usually milder form, caused by inheriting a sickle cell gene from one parent and a gene for Hemoglobin C (“C”) from the other.
HbS Beta-Thalassemia: Results from inheriting a sickle cell gene (“S”) from one parent and a beta-thalassemia gene from the other. Severity varies depending on the beta-thalassemia type (“zero” is severe; “plus” is milder).
Symptoms vary widely and can change over time, ranging from mild to severe. Early signs may include jaundice, fatigue, pain, and swelling in the hands and feet. Serious complications include severe anemia, infections, bone and chest pain, stroke, and organ dysfunction. While SCD is present at birth, many infants do not show symptoms until four to six months of age or later.
Anthony Wunderle Memorial Scholarship Fund
Established by Lori and Greg Wunderle in memory of their son Anthony who had childhood leukemia. This scholarship is to provide educational opportunities for a higher education, accredited trade, or apprenticeship program for any cancer survivor or family member of a cancer patient, living or deceased.
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Community Foundation for Mason County, MI
At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.
The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.
Danny McCarty Memorial Scholarship
This scholarship has been made possible by the generosity of the Family of Danny McCarty, who established the Danny McCarty Memorial Scholarship of the Community Foundation for Mason County. Deb Del Zoppo and her family established a scholarship in memory of her nephew, Danny McCarty, after he passed away at the age of 26 in a motorcycle accident in Colorado. Danny was involved in the construction trades, so the focus of the two-year scholarship ($500 each year) is to support students who are going into that field of study.
Fair Share Adult English for Speakers of Other Languages (ESOL) Services
The purpose of this competitive grant program is to expand the Public Adult Education (PAE) system's capacity to
Priorities:
Competitive priority will be given to applications that
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Summit, Portage, Stark, Carroll Nursing Scholarship (SPSCNS) Fund
Established to provide support to registered nurses living and/or employed in health care in Summit, Portage, Stark or Carroll counties who are pursuing an advanced master's or doctoral nursing degree.
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Scholarships for High School Seniors
Mid-Shore Community Foundation awards scholarships to high school seniors in Caroline, Dorchester, Kent, Queen Anne’s and Talbot Counties, who are planning to attend a college, university, or trade school. In general, scholarships are awarded to students who demonstrate academic achievement, community service, financial need, and other criteria specified by the donor.
Talbot Co. Public Schools Career and Technology Scholarship
Awarded to students graduating from Talbot County Public Schools, who are planning to attend a vocational, trade, or career school.
Charles Hayden Foundation
The Charles Hayden Foundation is committed to expanding opportunities for young people and helping them build the knowledge, skills, experiences, and relationships they need to thrive in school, work, and life.
We support youth-serving nonprofit organizations and public district, charter, Catholic, and independent schools, as well as organizations that strengthen the capacity of those serving young people. Our grantmaking spans academic success, social and emotional development, post-secondary pathways, and career-connected learning, with an emphasis on programs and organizations that create meaningful opportunities and demonstrate positive outcomes for young people.
The Foundation primarily supports young people from low-income communities in New York City and Boston, with some grantmaking in Newark, New Jersey.
Our Grantmaking
The Foundation focuses its grantmaking in the following areas:
Multi-Year Grant Opportunity: Supporting Strategic Plan Implementation
The Charles Hayden Foundation is launching a Multi-Year Grant Opportunity to help strengthen organizations and improve outcomes for young people in New York City and Boston. Through this opportunity, the Foundation anticipates inviting up to 10 organizations to receive multi-year project grants over a two- to three-year period to support strategic initiatives identified as priorities in their current strategic plans.
Proposed initiatives may build upon or enhance an existing Charles Hayden Foundation-supported program, such as hiring additional program staff to expand or strengthen services, or focus on an organizational capacity-building effort, such as implementing a new data and evaluation system.
Organizations selected for a Multi-Year Grant will receive a two- to three-year award that will replace their annual Charles Hayden Foundation grant for the duration of the grant period. Current annual grant funding will continue as part of the multi-year award, along with additional funding awarded to support the proposed strategic initiative. Organizations that are not selected will remain eligible to apply through the Foundation’s annual grantmaking process.
Project Criteria
Proposed projects should represent strategic investments that strengthen an organization’s ability to serve young people over the long term. Examples of eligible projects include:
The Foundation anticipates providing partial support for proposed initiatives and generally will not fund the full cost of a project. Award amounts will be determined based on the scope of the proposed initiative and the resources required for successful implementation. Because these grants support strategic initiatives over a two-to-three-year period, the Foundation anticipates that most requests will exceed an organization’s current annual Charles Hayden Foundation grant.
Operating grants for nonprofits provide essential funding to support day-to-day operations, staff salaries, and infrastructure. The following grants help organizations build capacity, maintain sustainability, and focus on achieving their mission-driven goals.
Explore 8,000+ funding opportunities for operational support, with $3.34B in resources. Instrumentl helps nonprofits secure essential funding by offering grant discovery tools, deadline tracking, and strategic funder analysis to ensure long-term success.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits?
Most grants are due in the first quarter.
What's the typical grant amount funded for Operating Grants for Nonprofits?
Grants are most commonly $32,500.
Nonprofits of all types can apply for operating grants, but they are especially useful for organizations needing flexible funding to support the core work of their mission. Operating grants are ideal for nonprofits involved in general population well-being. Specific sectors include healthcare, education, social services, and the arts. Unlike project-based grants that fund specific initiatives, operating grants help with essential costs like staff salaries, rent, and general admin costs. Funders often look for groups with a clear mission who serve a meaningful purpose and have potential for long-term impact.
Based on Instrumentl’s live grant database for operating, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Operating grants exist to help nonprofits function smoothly and grow effectively. The goal is to give organizations the financial means they need to focus on their mission, serve their communities, and support long-term stability. These grants allow nonprofits to improve everyday operations, invest in staff development, and expand programs. Funders want to see nonprofits thrive, not just survive, and providing operational support is a key element to making that happen.
Funding for operating grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Operating grants are often funded by private foundations like the popular Ford Foundation. Some government agencies offer grants to strengthen nonprofit infrastructure, especially in sectors like health, education, and social services. Corporate giving programs may also support nonprofits that align with their values and create lasting impact.
To improve the chances of getting operating grants, nonprofits should:
For more advice on finding and winning operating grants, check out our step-by-step guide to general operating grants.
Instrumentl simplifies the process of applying for operating grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.
Check out how Habitat for Humanity delivered over 200% ROI within just a few weeks.