Best Operating Grants for Nonprofits

The Elizabeth M. Pfriem Foundation, established in 2015 in Rye Brook, New York, is committed to enhancing the human condition through grants to 501(c)(3) public charities. Focusing primarily on the greater Bridgeport, Connecticut area, it supports initiatives in education, healthcare, food security, and housing. The foundation prioritizes organizations demonstrating fiscal responsibility and innovative programs with significant impact potential, ensuring sustainable support for vulnerable populations, especially children and families in need.

The Bloom-Hays Ecological Research Grant and Zembal Wetland Research Grant support ecological research in Southern California, focusing on avian species and coastal wetland habitats. Grants ranging from $250 to $2,500 are awarded to graduate and outstanding undergraduate students, promoting innovative research that benefits native species and habitats. Preference is given to projects directly related to local ecology, ensuring that funding addresses critical habitat issues in the region.

The Baiardi Family Foundation (BFF) awards grants primarily in Michigan, focusing on the Detroit Metropolitan Area and Emmet County. Their mission is to foster positive change through various giving categories, including healthcare, education, the arts, and environmental stewardship. They emphasize the importance of Catholic and Judeo-Christian values in their grant-making process. Note that they do not provide grants to individuals, and all requests are evaluated based on merit to align with their guiding principles.

Maryland Department of Natural Resources Forest Service

About Us

The Maryland Forest Service restores, manages, and protects Maryland’s trees, forests, and forested ecosystems to sustain our natural resources and connect people to the land.

MUCFC Grant Program

Community Tree Planting and Education Grant Program

The Maryland Urban and Community Forestry Council (MUCFC) provides funding to support community-based tree planting and forestry education projects that strengthen Maryland’s urban forests. Grants are open to organizations statewide for work on public lands that improves the urban tree canopy, engages citizens, and promotes long-term environmental stewardship.

The Fund for Change Grants support organizations advocating for social change, focusing on underserved communities. With an average grant size of $10,000-25,000, it funds initiatives in housing, behavioral health, criminal justice reform, and environmental justice. Eligible organizations can apply annually, but multi-year commitments are not available. The fund does not support capital campaigns, indirect costs, endowments, or individual scholarships, ensuring that funds are directed towards direct program expenses.

The Bargain Box of Hilton Head Grant, established in 1965, supports Beaufort County non-profits with cash grants derived from store sales. Operating as a 501(c)(3), it has contributed over $15.3 million to local charities, aiding in community activities related to education, health, and safety. Organizations must meet eligibility criteria, including having an active Board of Directors and a community focus. The grant fosters local engagement and supports a diverse array of charitable efforts.

The Robert B. and Ruth K. Lee Foundation Grant aims to enhance the quality of life in Greenville County, South Carolina. Established in 2000, the foundation supports diverse areas including arts, education, health, and human services. With no geographic limitations, it primarily funds programs benefiting the local community. Grants typically range from $2,000 to $5,000, emphasizing initiatives for the elderly, children’s programs in the arts, and literary projects. Organizations must be 501(c)(3) exempt to be eligible.

The United Way of St. Lucie & Okeechobee offers Community Impact Grants aimed at enhancing health, education, and financial stability in the community. Nonprofits serving these counties are encouraged to apply, provided they meet specific eligibility criteria, including being a 501(c)(3) organization and having operational experience of at least two years. This initiative focuses on addressing critical needs such as food security and housing assistance, fostering a sustainable and impactful community.

The BH UWC Consolidated Grant Program aims to enhance environmental equity by funding high-impact projects that address climate resilience and improve access to recreational spaces for disadvantaged communities. It aligns with the Cutting Green Tape initiative, focusing on strategic investments in conservation and community access. The program prioritizes projects that directly benefit vulnerable populations, ensuring equitable distribution of resources and measurable community benefits, thereby fostering sustainable development throughout California.

The Dombal-Vogel Foundation Grant supports children under 18 facing socio-economic challenges, offering funds for physical, mental, educational, adaptive, and legal needs. Established by Helen Dombal and Dolores Vogel in memory of their husbands, the foundation aids individuals and non-profits. Additionally, it provides financial assistance for young adults in health-related studies and those pursuing courses in hydrology, honoring Edward Dombal's legacy in water management.

The Arts Projects – Organisations Grants program, funded by the Australia Council for the Arts, supports diverse activities that enhance the arts sector and engage communities. With grants ranging from $20,000 to $100,000, eligible organizations can propose various initiatives including professional development, creative collaborations, and community engagement projects. Applications are open to organizations that benefit practicing Australian artists and audiences, fostering artistic innovation and cultural exchange.

The Delaware Agricultural Management Assistance (AMA) program provides financial assistance to producers for conservation practices, covering up to 75% of installation costs, with a cap of $50,000 per participant annually. This program aims to enhance water management, promote organic farming, and support historically underserved producers. Available in 16 states with low Federal Crop Insurance participation, AMA helps mitigate risks associated with agricultural production. Applications are accepted year-round, with specific cut-off dates for funding.

Our Mission

To advance Mayo Clinic’s commitment to be a socially responsible Enterprise by supporting and extending Mayo’s strategic mission of integrated practice, research and education through active community engagement practices.

Our Vision

To be a proactive partner, inclusive of diverse and underserved populations, and contribute to the overall health, sustainability, livability and vibrancy of the many communities we serve. Stakeholders will better understand and appreciate Mayo Clinic’s community engagement practices and our ongoing role in strengthening partnerships and creating positive social impact.

Community Contributions Program in Florida

Mayo Clinic in Florida is a not-for-profit organization with the primary mission of patient care. As a private trust for the public good, Mayo Clinic is dedicated to giving back to its local communities through its Office of Community Relations.

Mayo Clinic partners with others to ensure that:

• Our community investments align with our mission to advance patient care, research and education
• Our community is a welcoming, vibrant and healthy environment
• Our community is an environment that attracts and sustains a diverse Mayo Clinic workforce to provide the best patient care

Program Information

Mayo Clinic considers sponsorship and grant requests from registered 501(c)(3) organizations in northeast Florida for new/ongoing programs or other community outreach activities that support the stated goals. These may include:

• Health and Human Services
• Education and workforce development
• Belonging
• Youth enrichment
• Community events

Each request will be considered for alignment with any of the following health priorities:

• Access to Care
• Mental Health
• Food Environment - access to nutritious food

Access to Care

Mayo Clinic will offer one grant funding opportunity for the Community Health Needs Assessment priority area: Mental Health

The CRCF Youth Grants support initiatives that benefit teens aged 12-18 in Clinton, Eaton, and Ingham Counties, Michigan. With a focus on pressing issues like substance abuse, mental wellness, and violence, the grants are awarded through the Youth Advisory Council, consisting of local high school students. Eligible organizations include 501(c)(3) nonprofits, schools, and governmental entities. This program aims to empower youth and address critical challenges they face in today's society.

Just One More Grant aims to transform lives by providing financial support to individuals and nonprofit organizations in the U.S. who are overcoming challenges like mental health issues, drug misuse, and educational barriers. The foundation encourages applications from those committed to personal growth and community support. Though current grants are paused for nonprofits, interested individuals with actionable plans are invited to apply. More information and past winners can be found on their website.

The MA Agricultural Management Assistance (AMA) program supports agricultural producers in mitigating financial risks through diversification and conservation practices. Administered by NRCS, it provides financial assistance up to 75% for conservation costs, with a cap of $50,000 per participant annually. Eligibility includes land control and compliance with regulations. AMA is available in 16 states with historically low Federal Crop Insurance participation, promoting sustainable farming and resource management.

Native Seed growing Program (NV)

The State of Nevada, Department of Agriculture is seeking proposals from qualified vendors to provide native seed growing services as described in the scope of work and attachments. The State intends to award up to six (6) contracts in conjunction with this solicitation, as determined in the best interests of the State. The Department of Agriculture shall administer contract(s) resulting from this solicitation. The resulting contract(s) are expected to be for a contract term of four years, subject to Board of Examiner’s approval.

This project is a subset of a larger, partnership-driven project that aims to target 4 main objectives:

• Native seed collection;
• Native seed cleaning and storage;
• Native seed production; and
• Creation of a native seed equipment network.

This particular project addresses one primary objective: enhancing native seed production in Nevada. We intend to achieve this through both a physical increase in the total supply of a diverse cache of native species and increasing the technical knowledge and experience of growing native species for Nevada-based producers. The achievement of this objective is entirely reliant upon the ability of local landowners and agricultural producers to plant seed stock that will enable restoration practitioners to have access to desirable, locally adapted speciesfor re-seeding projects.

 Project managers will be tasked with the goal of obtaining the appropriate starter seed and providing those species to eligible producers for increase, while simultaneously selecting seed that is genetically appropriate for replanting within the Great Basin region. Eligible producers will be provided with technicalsupport and the best possible plant materials throughout the project period. It is the intent of this project to fund production efforts for increase by way of state contracting and to obtain an increase in materials used for public restoration projects statewide. Seed yields from increase efforts will be re-admitted to the funding agency and ultimately will be re-allocated to federal and state agencies for use on restoration projects throughout the Great Basin. Funding for production will vary based upon species selected and is limited to 3 overarching categories:

• $4,000.00/acre, 
• $5,000.00/acre,
• $6,000.00/acre

The total amount of funding available to support this initiative is $316,445.00. 

The IAF Research Fellowship Program, administered by the Social Science Research Council, aims to support rigorous research on community-led development in Latin America and the Caribbean. The fellowship provides a $20,000 stipend for twelve months, fostering innovative solutions to pressing issues such as economic opportunity, migration, and social inclusion. Researchers are encouraged to explore how community-led models can create lasting impacts and respond to global trends, enhancing local resilience and development.

The Jacob and Hilda Blaustein Foundation focuses on promoting health and mental health, as well as strengthening public education in Baltimore. Through its health initiatives, the foundation seeks to enhance access to mental health services and advocate for systemic changes. In education, it supports efforts to improve leadership and teaching quality in public schools, aiming to create equitable opportunities for Baltimore youth. This foundation prioritizes innovative programs that engage communities in meaningful ways.

The Allianz Life Insurance Company of North America offers the Financial Sustainability Grant to support nonprofit organizations that promote economic inclusion and financial stability. Grants range from $50,000 to $75,000 for one-year commitments, focusing on workforce success through education, job training, and entrepreneurial support. Eligible organizations must be tax-exempt under IRS 501(c)(3) and primarily serve low- to moderate-income families in the Twin Cities metro area.

The Active Transportation Grant, offered by Columbia Basin Trust, supports communities in enhancing their non-motorized travel options. This program funds the planning and construction of multi-use pathways, promoting walking, cycling, and wheeling. By creating safe routes for all ages and abilities, it aims to reduce pollution and foster healthier, more accessible communities. Applications are accepted continuously until the available funds are committed, enabling timely support for local initiatives.

The Giving Tree – Early Literacy Grants, offered by the Arkansas Community Foundation, aim to enhance early literacy among children. These grants support initiatives that engage parents, improve school readiness, bolster classroom instruction, and address attendance issues. They are designed for 501c3 nonprofits, schools, and government entities. By focusing on various aspects of early education, these grants seek to ensure that every child in Arkansas has the resources and support necessary to thrive academically.

Executive Summary

The New Jersey Department of Health (NJDOH), Division of Health Promotion – Community Health and Wellness Unit (CHWU) addresses leading causes of death and disability from chronic disease and illness. The core mission of the CHWU is to prevent premature death and disability from chronic disease, to understand the risk factors of chronic disease, and to promote healthy behaviors through leadership efforts that address evidence-based policies, systems, and environmental change. To achieve this mission, the CHWU has cultivated a robust group of partners – clinicians, academicians, community advocates, patients, consumer representatives, business leaders and government agencies – across the state of New Jersey to reach high burden populations and communities and complete funded work. Improved quality of life and extended years of healthy living for New Jersey residents are the overall outcomes for all activities undertaken through CHWU programs and services.

The Community Health and Wellness Unit’s – Colorectal Cancer Screening and Prevention Program announces the availability of State Fiscal Year (SFY) 2026 funding and technical assistance for primary care clinics operating in Cumberland, Cape May, Gloucester, Monmouth, Hunterdon, Somerset and Essex counties whose colorectal cancer (CRC) screening prevalence is between 25% and 55%, to implement evidence-based interventions (EBIs) and quality improvement (QI) processes to increase CRC screening in eligible and priority populations. This RFA seeks to increase CRC screening among populations aged 45 to 75 years that have lower colorectal cancer screening prevalence. The NJDOH-CCSPP is seeking up to four (4) primary care clinics to adopt strategies that utilize multi-component EBIs to increase CRC screening and to partner with NJDOH-CCSPP by accepting technical assistance, and support for data collection and evaluation activities.

Funded entities must demonstrate capacity and readiness to implement the program by completing the following:

• Engage in a formal readiness assessment of funded entities’ capacity to implement EBIs. This assessment will be used to select EBIs that will support improved CRC screening.
• Implement multicomponent interventions that combine a minimum of three (3) evidence-based interventions (EBI), as recommended in The Community Guide. These EBIs must focus on different areas of the clinical system (which will increase demand, access, and delivery of screening recommendations). The EBIs of priority for this work includes patient reminders, provider reminders and feedback, reducing structural barriers, and patient navigation.
• Provide high-quality, clinic-level data, including baseline and annual CRC screening prevalence, aggregate data on stool-based tests provided to and returned by patients, and aggregate data on follow-up colonoscopies. Emphasis will be on the capacity to collect data and track the entire CRC screening process patients undergo.
• Support completion of stool tests and colonoscopies, including tracking and follow-up of colonoscopies for positive stool tests

In addition to funding and technical assistance, each awardee will have the opportunity to utilize a free patient navigation service supported by NJDOH. The navigators will be deployed to the awardees primary care clinics site and will provide direct patient referrals and outreach via electronic health records (EHR). Leveraging innovative tools, including a patient chat text concierge, the patient navigators will enhance patient engagement, reduce barriers, and empower informed decision-making. Navigators will also coordinate care, track outcomes, schedule screenings, and ensure timely follow-up to promote comprehensive, equitable colorectal cancer prevention and care.

The Gordon Foundation for Children and Youth offers the Special Projects Grant Program to support initiatives that enhance the mental health and well-being of children and youth. This program funds a variety of projects, including sensory rooms for children with special needs, newsletters for youth in care, and educational trips for urban students to rural communities. Eligible applicants include individuals, schools, and organizations dedicated to improving youth mental health.

The NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) support small businesses in conducting clinical trials for NIH-funded projects. This initiative encourages partnerships with investors to assist in the commercialization of innovations in neurological disorders. Applicants must submit a comprehensive Commercialization Plan detailing anticipated funding. The program aims to promote effective transitions from research to market, enhancing the development of drugs, devices, and therapies for neurological conditions.

The Drinking Water State Revolving Fund (DWSRF) program, managed by the California State Water Resources Control Board, provides essential financial assistance for public water systems. It supports the planning and execution of drinking water infrastructure projects to ensure compliance with Safe Drinking Water Act requirements. Eligible costs cover planning documents, engineering specifications, environmental reviews, and more, facilitating access to safe drinking water and promoting the human right to water.

The CityArts Program Grants, offered by the Chicago Department of Cultural Affairs and Special Events, support local artists and cultural organizations by providing general operating grants based on average annual revenue. Eligible nonprofits can apply for grants ranging from equal to their revenue for smaller organizations to a maximum of $50,000 for larger ones. This initiative aims to enhance access to the arts across Chicago's diverse neighborhoods.