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Best Columbia Grants for Nonprofits in South Carolina

Looking for grants for 501(c)(3) nonprofit organizations working in Columbia, South Carolina? Find the perfect grant for your nonprofit on Instrumentl.

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$5K

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9,000+ grants
$3.79B total
$5K median

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9,123 Results based on applied filters

Mentored Student Pilot Projects (MSP) NOFO

South Carolina IDeA Network of Biomedical Research Excellence (SC INBRE)
State/Local Government
Aiken County, South Carolina, Anderson County, South Carolina +10 more
Up to US $3,000
The SC INBRE: Mentored Student Pilot Projects (MSP) program offers undergraduate and graduate students in South Carolina funding of $3,000 for one year to conduct small, well-defined research projects under faculty mentorship. This initiative supports career development and hands-on training in biomedical research, enhancing the research capacity of member institutions. Applications are encouraged from students who have not previously held an SIRP award, fostering diversity in research participation.
Bioengineering Cell Biology Neuroscience +4 more

Union Home Foundation Grant

The Union Home Foundation Inc
Private
Ada County, Idaho, Aiken County, South Carolina +183 more
More than US $1,000
The Union Home Foundation Grant provides financial support to nonprofit organizations that promote economic self-sufficiency through financial literacy and housing initiatives. Established in 2015, this grant has awarded over $2 million to various nonprofits across the U.S. Grants typically start at $1,000 and are available for a one-year period. Organizations must be 501(c)(3) tax-exempt and can only apply once per year, following specific eligibility criteria.
Financial Literacy Equitable & Affordable Housing Supportive Housing & Shelters

Bobbi Rossi Memorial Scholarship – USC School of Nursing

Central Carolina Community Foundation
Private
Richland County, South Carolina
Unspecified amount

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Bobbi Rossi Memorial Scholarship – USC School of Nursing ($2,600)

This renewable scholarship is available to current students in upper-division (Junior/Senior year) or have admission to the upper-division College of Nursing at the University of South Carolina-Columbia. 

Education - Higher Education Academic Scholarship Programs Nursing

Cox Enterprises Scholarship Program

United Negro College Fund Inc
Private
Bamberg County, South Carolina, Davidson County, Tennessee +30 more
Up to US $5,000

Cox Enterprises Scholarship Program

A need-based scholarship for students attending UNCF member institutions with preference given to students majoring in STEM.

Individual Award

  • Up to $5,000
Education - Higher Education STEM / STEAM Education

The Justin Richard Lopes University of South Carolina Award

Cumberland Community Foundation, Inc.
Private
Richland County, South Carolina
Unspecified amount

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

The Justin Richard Lopes University of South Carolina Award

Graduating senior from any high school in Cumberland County.

Education - Higher Education Career / College Preparation

Weyerhaeuser Giving Fund Grants

Weyerhaeuser Giving Fund
Corporate
Ada County, Idaho, Adams County, Colorado +392 more
More than US $1,000
The Weyerhaeuser Giving Fund provides grants to support communities in the U.S. and Canada where the company operates. Focused on affordable housing, education, environmental stewardship, and more, the fund emphasizes projects that meet local needs and demonstrate community support. Eligible organizations include nonprofits and educational institutions. Applications are accepted year-round with a deadline for 2025 on September 30. National initiatives related to working forests are funded by invitation only.
Education Environment Environmental Education +25 more

Harmon Scholarship

Central Carolina Community Foundation
Private
Pickens County, South Carolina, Richland County, South Carolina
Unspecified amount

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Harmon Scholarship (Full Tuition, plus on-campus housing and meal plan) 

This renewable scholarship was established to help students realize the American Dream. 

Education - Higher Education Mental Health & Psychiatric Diseases Academic Scholarship Programs +1 more

Samantha and Kyle Busch Bundle of Joy Fund Grant

Samantha and Kyle Busch Bundle of Joy Fund
Association/Society
Berkeley County, South Carolina, Buncombe County, North Carolina +7 more
Up to US $20,000

Every Dream of Parenthood Deserves a Chance

Making dreams of parenthood a reality, one grant and one bundle of joy at a time.

Our Mission

The Samantha and Kyle Busch Bundle of Joy Fund is dedicated to advancing access to IVF care and coverage, increasing awareness and providing support so others don’t have to navigate infertility alone.

Apply for a Grant

Your Journey to Parenthood Begins Here

We distribute grant awards up to three times annually.

Please note that the number of grants and funding amounts fluctuate based on:

1) the unique needs of our applicants, and

2) the success of our fundraising efforts.

Our mission is to help as many people as possible.

Obstetrics & Neonatal Care Maternal And Perinatal Health Health Care Access & Delivery

Gerhard Metzen Scholarship

Central Carolina Community Foundation
Private
Richland County, South Carolina
Unspecified amount

About

Central Carolina Community Foundation is a nonprofit organization that helps generous people give back to the Midlands of South Carolina in ways that matter. Since 1984, we’ve been a trusted partner, helping individuals, families, and businesses make smart, meaningful contributions that support local nonprofits, scholarships, and community projects.

Gerhard Metzen Scholarship ($2,200) 

This renewable scholarship is for current or incoming students at Midlands Technical College (MTC) in Columbia, SC for a degree or certificate program. 

Education - Higher Education Academic Scholarship Programs

Basic Needs and Income Creation

Bank Of America Charitable Foundation Inc
Private
Abbeville County, South Carolina, Ada County, Idaho +198 more
Unspecified amount
The Bank of America Charitable Foundation focuses on improving economic mobility and social progress through partnerships with nonprofits. It prioritizes basic needs, income creation, stable housing, and community empowerment. By supporting vulnerable populations, the foundation aims to enable individuals to achieve their goals and contribute positively to their communities. The foundation emphasizes sustainable progress, ensuring that all community members have access to essential resources and opportunities for growth.
Basic Human Needs Economic Services & Development Employment Services +2 more

Academy Sports + Outdoors Donations

Academy Sports + Outdoors
Corporate
Aiken County, South Carolina, Alamance County, North Carolina +211 more
Unspecified amount
Academy Sports + Outdoors, a leading sporting goods retailer, supports community initiatives by providing donations to registered 501(c)(3) organizations. Their focus is on promoting safety and responsibility in sports and outdoor activities. Proposals must foster community engagement and must not be affiliated with religious or political groups. Events should take place in areas with Academy stores, ensuring a positive local impact while encouraging active lifestyles and connection among community members.
Recreation Outdoor Recreation Sports & Athletics +1 more

Thelma M. Shafran Endowed Scholarship

United Negro College Fund Inc
Private
Davidson County, Tennessee, Fulton County, Georgia +9 more
Up to US $6,000

About Us

For more than eight decades, this principle has remained at the heart of UNCF, enabling us to raise more than $6 billion and help more than 550,000 students and counting not just attend college, but thrive, graduate and become leaders.

We do this in three ways: By awarding more than 11,000 students scholarships, worth more than $62 million, each year. By providing financial support to 37 historically Black colleges and universities (HBCUs). And by serving as the nation’s leading advocate for the importance of minority education and community engagement.

This three-pronged approach is powerful: Since our founding in 1944, we’ve helped to more than double the number of minorities attending college. The six-year graduation rate for UNCF African American scholarship recipients is 70%. This is 11% higher than the national average and 31% higher than the national average for all African Americans.

Thelma M. Shafran Endowed Scholarship

Education - Higher Education Black American Services Academic Scholarship Programs +1 more

ArtsNOW Schools Advancement Grants

South Carolina Arts Commission
State/Local Government
Aiken County, South Carolina, Anderson County, South Carolina +21 more
Unspecified amount
The ArtsNOW Schools Advancement Grants aim to enhance educational experiences in identified ArtsNOW Partner Schools through arts integration. This three-year program supports professional learning, curriculum mapping, and ongoing school assistance to engage students and empower educators. With funding ranging from $44,000 in the first year to $17,000 in the third, the grant fosters innovative practices to cultivate vibrant school communities. The initiative encourages creativity while addressing the specific needs of each participating school.
Arts / Culture Access & Participation Youth Involvement in the Arts

Stable Housing and Empowering Communities

Bank Of America Charitable Foundation Inc
Private
Abbeville County, South Carolina, Ada County, Idaho +198 more
Unspecified amount
The Bank of America Charitable Foundation focuses on supporting organizations that empower communities through basic needs, income creation, and stable housing. By investing in health and job opportunities, they aim to enhance economic mobility for low- and moderate-income families. Their partnerships target vulnerable populations, ensuring equitable access to resources that foster community vitality and resilience. This initiative emphasizes the importance of stable housing as a foundation for personal and communal growth.
Real Estate & Housing Equitable & Affordable Housing Community Development & Revitalization

PNC Foundation: Foundation Grant

PNC Foundation
Private
Accomack County, Virginia, Adams County, Colorado +667 more
Unspecified amount
The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.
Education - Preschool / Early Learning Teacher Development & Training Music Education +16 more

LeBlanc/Baker Scholarship for Change

United Negro College Fund Inc
Private
Bamberg County, South Carolina, Davidson County, Tennessee +30 more
US $4,000

LeBlanc/Baker Scholarship for Change

LeBlanc/Baker Scholarship for Change provides a renewable need-based scholarship to male students attending an accredited, four-year Historically Black College or University (“HBCU”).

LeBlanc/Baker Scholarship for Change award recipients will receive a 2026-2027 academic year award of up to $4,000 based on need. UNCF will send electronic notification to the eligible recipients in April 2026; and scholarship funds will be disbursed to the eligible recipients’ enrolled institutions in the fall 2026.

Scholarship Renewal

If funds are available, recipients may be eligible for awards for up to four (4) additional years within a five (5) year period.

Previously awarded students shall be notified and must meet the following criteria:

  • Maintain academic standing consistent with the student’s institution standards for continued enrollment.
  • Annually complete FAFSA and continue to have a demonstrated unmet financial need, as verified by their college or university.

A student who transfers from an HBCU to any accredited four-year college or university after successfully completing at least one (1) academic term remains eligible for recurring awards for attendance at their new institution if they otherwise meet the renewal eligibility criteria.

A student who withdraws or takes a leave of absence, after completing at least one (1) academic year, has the equivalent of a full academic year to reenroll at any accredited four-year college or university.

Education - Higher Education

Do it Best Foundation Grant

Do It Best Foundation Inc
Private
Allen County, Indiana, Clark County, Nevada +9 more
Unspecified amount
The Do it Best Foundation Grant supports nonprofit organizations focused on community needs, particularly in health and wellness, youth enrichment, the arts, and community development. Grants typically range from $5,000 to $20,000, with no strict limits based on quarterly applications. Eligible organizations must have 501(c)(3) status and be located near specific areas. This initiative aims to enhance community resources and foster connections among residents.
Art & Culture Youth Services Health Care Access & Delivery +3 more

Wabtec Direct Grant Program

Wabtec Foundation
Corporate
Ada County, Idaho, Alamance County, North Carolina +70 more
US $1,000 - US $10,000
The Wabtec Direct Grant Program focuses on creating sustainable impacts in local communities by funding 501(c)(3) non-profit organizations. Emphasizing education and environmental stewardship, the program supports initiatives that improve literacy, academic outcomes, and workforce readiness. Grants range from $1,000 to $10,000, prioritizing organizations that engage local Wabtec employees in volunteerism. The program promotes equitable access and non-discrimination while ensuring measurable results in funded projects.
All fields of work Literacy Academic Success & Enrichment +10 more

Knight Foundation Advised Fund

Central Carolina Community Foundation
Private
Richland County, South Carolina
Unspecified amount
The Knight Foundation Advised Fund supports innovative projects that enhance democracy and community engagement in Columbia, SC. With grant amounts typically not exceeding $75,000, it focuses on revitalizing downtown areas and riverfront development. Eligible organizations must be 501(c)(3) charities or similar entities serving Columbia or Richland County. The foundation prioritizes civic engagement, smart design, and the arts to foster inclusive public life, while avoiding funding for debt reduction, capital campaigns, or projects with discriminatory practices.
Civic Engagement & Education Parks & Public Spaces Community Development & Revitalization +7 more

GSF Foundation Grant

GSF Foundation
Private
Clark County, Nevada, Cook County, Illinois +23 more
Unspecified amount
The GSF Foundation Grant supports 501(c)(3) non-profit organizations that enhance the lives of children and families in need. Applications must be submitted by a current GSF Associate who nominates the organization and its project. Since 2002, the foundation has funded over 600 organizations nationwide. It emphasizes personal involvement and contributions from associates, focusing on essential needs such as education tools, food, and shoes for children. Grants are reviewed at local and national meetings.
Children’s Health & Pediatrics Youth Services Family Services +3 more

Knight Cities Challenge

John S And James L Knight Foundation Inc
Private
Allen County, Indiana, Baldwin County, Georgia +24 more
Up to US $200,000

About Knight Foundation

John S. and James L. Knight believed that a well-informed community could best “determine its own true interests” and was essential to a well-functioning, thriving democracy. They pursued those beliefs, building and leading one of the largest and most successful newspaper companies in American history.

For 75 years, Knight Foundation has supported the people, ideas and insights that lead to thriving communities. The foundation invests in local journalism, arts and culture and community development in the 26 cities and towns where the Knight brothers once published newspapers.

Since our founding in 1950, we have been committed to the communities we serve and to providing those communities with the tools they need for residents to thrive.

Knight Cities Challenge

Knight Foundation is currently accepting applications for the Knight Cities Challenge, a $5 million open call inviting individuals and organizations across its 26 communities to submit new, creative ideas for projects that can spark change and leave a lasting local impact.

Building on a long history of open challenges across programs, Knight democratizes access to grantmaking to unlock the best and brightest ideas. This spring, KCC returns to invest in its first cohort of community-centered solutions to local challenges and help promising ideas take root and grow.

Project ideas must focus on at least one of Knight’s investment areas: strengthening local news and information, creating pathways for economic opportunity or cultivating connection through arts, culture and the places that bring people together.

You may submit one idea, either as an individual or on behalf of your organization. While you are limited to one application as the lead applicant, you may collaborate on other projects submitted by different partners. Each individual or organization may receive funding for only one project.

For large institutions such as universities or city governments, schools or departments are considered separate entities. 

Journalism News Media & Communications Economic Services & Development +1 more

Publix Cares Scholarship

United Negro College Fund Inc
Private
Chatham County, Georgia, Chesterfield County, Virginia +6 more
Up to US $2,000

Publix Cares Scholarship

Publix Cares Scholarship was established by Publix Super Markets, Inc., a Florida corporation, in partnership with UNCF to provide scholarships to eligible students attending at one of the following selected institutions.

College/Universities

  • Bethune Cookman University
  • Florida Agricultural and Mechanical University
  • University of Central Florida
  • Benedict College
  • Clark Atlanta University
  • Savannah State University
  • Morehouse College
  • Spelman College
  • Virginia State University

Tennessee State UniversitySelected student will receive up to $2,000 need-based scholarship in the fall 2026.

Education - Higher Education

PNC Foundation: Grow Up Great Grant

PNC Foundation
Private
Accomack County, Virginia, Adams County, Colorado +667 more
Unspecified amount
The PNC Foundation's Grow Up Great Grant is a significant initiative aimed at enhancing educational opportunities for children from birth to age 5. With a commitment of $500 million, this program focuses on improving school readiness through support in vocabulary development, social-emotional learning, and the arts. By partnering with community-based nonprofits, PNC aims to foster stronger, smarter, and healthier communities, ensuring a brighter future for the next generation.
Education - Preschool / Early Learning Teacher Development & Training Parental Involvement in Education +4 more

Foot Locker Foundation, Inc-UNCF Scholarship

United Negro College Fund Inc
Private
Bamberg County, South Carolina, Davidson County, Tennessee +30 more
Up to US $5,000

Foot Locker Foundation, Inc-UNCF Scholarship

Foot Locker Foundation, Inc. has partnered with UNCF to fund this scholarship program for students attending a UNCF member college or university during the 2026-2027 school year.

Foot Locker Foundation works to improve upward mobility to build a more equitable and inclusive future through education, economic development and community empowerment. For nearly twenty years, it has partnered with leading organizations helping to mobilize and uplift local communities. 

When applying, a UNCF member school will appear in the drop down options in the application. 

Completed application packages include: transcript, essay, and one letter of recommendation from a faculty member, employer or other community member familiar with your academic performance. All information will be submitted in the appropriate section of the online application.

Individual Award

  • Up to $5,000.00
Education - Higher Education

Tyson Foods: Community Giving Grants

Tyson Foods, Inc.
Corporate
Accomack County, Virginia, Alameda County, California +93 more
US $500 - US $5,000
Tyson Foods Community Giving Grants support initiatives that enhance the quality of life for communities and their members. With a focus on scaling existing effective programs, these grants are aimed at organizations that operate in underserved areas. Eligible nonprofits must have a 501(c)(3) status and local Tyson plant support. Applications are accepted annually, with priority given to projects addressing systemic community issues. Notable past support includes a $25,000 grant to the Arkansas Foodbank Mobile Pantry Initiative.
Food Access & Hunger Volunteerism & Philanthropy

Lexington Medical Center Grant

Lexington Medical Center Foundation Inc
Private
Lexington County, South Carolina
Unspecified amount
The Lexington Medical Center Grant supports 501(c)(3) nonprofit organizations that address community health care needs in the Midlands. The foundation prioritizes increasing access to healthcare for underserved populations, enhancing education on health issues, and fostering collaboration with existing healthcare initiatives. Their goal is to bridge health care gaps and improve the capacity of safety-net services, ensuring vulnerable populations receive necessary support and services.
Health Disparities & Social Determinants of Health

Westinghouse CFFF Charitable Giving Program - Columbia Fuel Fabrication Facility

Westinghouse
Corporate
Richland County, South Carolina
Unspecified amount

The Westinghouse CFFF Charitable Giving Program

Westinghouse believes in giving back to surrounding communities.

The enables our company to provide financial support to the areas around our facility, including Hopkins, Gadsden and Eastover. Grants will be provided in one or more of our strategic areas of giving. This is just one way Westinghouse gives back to its community.

Westinghouse strategic areas of giving:

If your organization meets the criteria of one or more of our strategic areas of giving, we welcome you to apply for a grant.

Sustainability Military & Veterans Services Community / Public Safety +12 more

Columbia Grants for Nonprofits Highlights

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