Best Columbia Grants for Nonprofits in South Carolina

The PNC Foundation aims to enhance the lives of individuals in local communities through partnerships with nonprofit organizations. Their focus includes promoting educational opportunities, particularly for early childhood education, and supporting economic development initiatives. Grants are available for organizations that benefit low- to moderate-income families and enhance community growth. The foundation prioritizes programs that foster sustainability and diversity, ensuring a lasting impact on the communities they serve.

The Pathways to Enable Secure Open-Source Ecosystems (PESOSE) program, funded by the National Science Foundation, aims to transform open-source research into sustainable ecosystems that tackle national and societal challenges. This initiative promotes innovation across various sectors, including AI and cybersecurity, by fostering strong governance and broad user engagement. PESOSE invites proposals to establish and enhance open-source ecosystems, ensuring their safety, security, and effectiveness in meeting emergent needs.

The RAK Education Foundation Scholarship provides financial assistance to residents of Camden, Chowan, Gates, Pasquotank, or Perquimans Counties who have earned a high school diploma or GED. This scholarship supports students pursuing degrees or certificates in Career and Technical Education fields such as trade education, computer science, business, health science, and more. Applications open on December 16, 2025, and close on March 3, 2026, encouraging eligible students to apply.

The National Quantum and Nanotechnology Infrastructure (NQNI) program by the NSF aims to enhance research in emerging technologies like quantum computing and AI. By establishing a nationwide network of accessible research facilities, NQNI will facilitate innovation and collaboration among researchers. The program emphasizes user facility capabilities and plans for outreach, education, and workforce development, ultimately supporting the nation's quantum and nanotechnology advancements.

The Robert E. Barnhill, Sr. Scholarship Fund provides financial support for North Carolina high school seniors who plan to attend a four-year college or university as full-time students. Eligible applicants are evaluated on leadership potential, community involvement, academic achievement, and financial need. The scholarship may be renewed for up to three additional years, contingent upon maintaining a 2.0 GPA and continuous enrollment. Applications open on December 16, 2025, and close on March 3, 2026.

The Peter S. Slomianyj Scholarship Fund offers financial assistance to Subway employees and their children who meet specific eligibility criteria, including a minimum of 500 work hours over the past year and a GPA of 2.0 in high school or 2.5 in college. Applications for this scholarship will be open from December 16, 2025, to March 3, 2026. It is part of a broader initiative by the North Carolina Community Foundation to support students pursuing education at various institutions.

The National Science Foundation (NSF) is offering Postdoctoral Research Fellowships in Biology to support innovative research at the intersection of Artificial Intelligence (AI) and Biological Sciences. These fellowships aim to cultivate expertise in both fields, enabling scientists to leverage AI for breakthroughs in biotechnology and bio-system design. The program encourages proposals that utilize existing biological data and infrastructure to enhance discovery and innovation, ultimately benefiting human lives and the U.S. economy.

The ROSES25: B.2 Heliophysics Foundational Research program invites proposals for foundational research in heliophysics. The submission deadline for Step-1 proposals is May 1, 2026, with Step-2 deadlines announced 60 days prior. Amendments include an increase in Step-1 proposal length from two to three pages and clarification on budget expectations per award. Individuals may serve as Principal Investigators for only one proposal, with exceptions for specific institutional requirements.

The Ruby A. Trivette Ruritan Scholarship, administered by the North Carolina Community Foundation, supports graduating seniors from Ashe and Watauga counties in North Carolina. Eligible applicants must reside in Todd or be active members or children of active members of the Todd Ruritan Club. This scholarship opens for applications on December 16, 2025, and closes on March 3, 2026, providing crucial financial assistance for students pursuing higher education.

The Sammy and Shirley Church Scholarship supports students from Ashe County, NC, including those graduating from the NC School of Science and Math. Eligible candidates must demonstrate academic excellence, physical vigor, and leadership in various activities. Financial need is considered but not the only criterion. Applications open on Dec. 16, 2025, and close on March 3, 2026. Ensure to meet specific eligibility requirements set by the donor for successful application.

What We Do

At the North Carolina Community Foundation, we bring together generous people and connect them to causes and organizations they care about.

Our mission is to inspire North Carolinians to make lasting and meaningful contributions to their communities.

Our Philanthropic Network

We believe in the power of permanent philanthropy to strengthen our communities and people. By stewarding and growing donors’ gifts, our philanthropic network makes a powerful impact through robust grants and scholarships programs.

Humphrey-Ragsdale Scholarship Fund

Criteria

Residents of Craven County or graduates of a Craven County high school who are pursuing higher education at a two-year or four-year college or university, community or technical college, apprenticeship program, or pursuing graduate school or other professional degree such as dental, medical, law or seminary. Preference for those with a connection to First Baptist Church of New Bern, including but not limited to a church member, family of a church member, employee or former employee, family of employee or former employee, or youth group member.

The Bertha Sawyer Meiggs & Winfred B. Meiggs Sr. Family Scholarship supports graduating seniors from Camden, Gates, Pasquotank, and Perquimans counties, with a preference for Camden County residents. Eligible candidates must demonstrate strong academic performance, leadership skills, and community involvement while enrolling full-time in a two- or four-year college. The scholarship may be renewed at the discretion of the Scholarship Committee, subject to academic criteria and available funds.

The Reid Sasnett Memorial Scholarship Endowment supports graduating seniors from Pungo Christian Academy and Beaufort County high schools pursuing higher education. This scholarship aims to aid students who exhibit strong character, leadership, and community service, especially those passionate about agriculture and wildlife. Applications open on Dec. 16, 2025, and close on March 3, 2026, with preference for volunteer firefighters and Pungo Academy alumni.

The Agriculture and Food Research Initiative (AFRI) focuses on enhancing education and workforce development in food and agricultural sciences. It invites applications for various grants aimed at professional development, non-formal education for youth, community college training, and fellowships for both predoctoral and postdoctoral candidates. The program, managed by the USDA's National Institute of Food and Agriculture, emphasizes the cultivation of skills necessary for the future workforce in agriculture, with multiple deadlines for submissions.

The ROSS Rapid Response Program (RRP) by the U.S. Department of Housing and Urban Development (HUD) provides expedited funding to assist communities in addressing urgent social needs. This program offers one-time cost-reimbursable grants for service coordination and direct services, especially in response to emergencies like natural disasters or public health crises. By streamlining the application process, the RRP empowers local leaders to efficiently support residents in HUD-assisted housing, promoting self-sufficiency and resilience.

The Scottie W. Cox Memorial Scholarship of NCCCLA supports employees of learning resources centers in North Carolina pursuing advanced degrees in library and information studies. Eligible applicants must have at least a bachelor's degree and be enrolled in accredited programs. This scholarship, administered by the North Carolina Community Foundation, opens for applications on December 16, 2025, and closes on March 3, 2026. It aims to enhance professional development in the library sector.

Bridgestone Americas Trust Fund Grants

Empowering People to Move, Live, Work, and Play

Bridgestone has awarded over $60 million to nonprofit organizations in the United States since 1951, and we are committed to continuing our legacy of giving back by supporting communities around the U.S.

Bridgestone works with grantseekers that offer solutions to keep society moving forward. Strong partners offer a human-centered approach to societal challenges in one or more of the following areas of focus: 

In addition to our three areas of focus, we will consider applications from organizations that have hosted volunteer or community engagement events with Bridgestone volunteers and organizations that have received funding in previous years. 

Adaptive Sports in Schools Mobility Grants

Request for Proposals

More than 7 million students in the U.S. receive special education services for disabilities in public schools. A 2010 study by the U.S. General Accountability Office found that students with disabilities participated in athletics at significantly lower rates than their peers. Currently, 2,490 k-12 public schools in the U.S. are members of the American Association of Adaptive Sports Programs schools and have adaptive sports programs for students.

The Bridgestone Americas Trust Fund seeks public schools pursuing funding to start adaptive sports programs or increase access to adaptive sports and equipment for children and youth. Bridgestone is offering eight $25,000 “mobility” grants to organizations that can establish new athletic programming for students with disabilities. Organizations must articulate a clear plan to provide access to new athletic programs for students with disabilities in one or more public schools for students grades K-12.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a student who intends to pursue nursing or a related field of study at a college or university, and who demonstrates academic achievement, good citizenship, service to others, leadership, and financial need.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating senior from a high school in Lackawanna County who is matriculating to a college or university to study in the field of education.

Who We Are

Buiding a stronger, More Vibrant Community

For over 70 years, the Scranton Area Community Foundation has served Northeastern Pennsylvania as a steward of charitable resources, a grantmaker, and a catalyst for positive change. Guided by our core values of collaboration, trust, integrity, innovation, and inclusivity, we work to ensure that our communities thrive with opportunities for all.

This scholarship is awarded to a graduating high school senior who is a current employee of a McDonald’s restaurant located in Northeastern Pennsylvania.

The HEAL Initiative Whole Joint Health Program aims to advance research on the biological mechanisms of joint pain by exploring the interactions of various tissues within the joint. This innovative program will support clinical studies that focus on non-pharmacological interventions to enhance healing and improve quality of life for individuals suffering from chronic joint pain. By fostering a comprehensive understanding of joint health, the initiative aligns with the NIH's broader goals to reduce chronic pain and opioid dependency.

The Limited Competition Small Grant Program for the NCATS CTSA Program aims to empower KL2 scholars by funding diverse clinical and translational research projects. These grants support short-term studies, methodology development, and preliminary data collection, facilitating the transition to independent research careers. Applications will undergo NIH peer review, ensuring only high-quality proposals receive funding. This initiative fosters innovation in research methodologies and technology, ultimately enhancing the capabilities of emerging translational scientists.

The National Library of Medicine (NLM) is inviting applications for its Coordinating Center within the Network of the National Library of Medicine (NNLM). Established in 1965, the NNLM enhances public access to health information through collaboration with libraries and community organizations. The NCC will oversee network administration and evaluation, fostering partnerships and supporting local clinical research. This initiative aims to expand NIH engagement and improve public understanding of health resources and information available through the NNLM.

The NLM Institutional Grants aim to enhance training in biomedical informatics, data science, and AI for predoctoral and postdoctoral researchers. By fostering innovative programs, NLM addresses the urgent need for experts in these fields to tackle complex health challenges. These grants support both new and renewed training initiatives, emphasizing interdisciplinary approaches that combine diverse methods to advance biomedical science and improve health outcomes through advanced computational strategies.

The Collaborative Program Grant for Multidisciplinary Teams, funded by the US Dept. of Health & Human Services: National Institutes of Health (NIH), supports integrated teams of researchers tackling ambitious projects that individual efforts cannot achieve. This program promotes collaboration among experts with complementary skills, aiming for significant advancements in their fields. Teams are encouraged to pursue innovative objectives that have the potential to transform research landscapes.

The National Library of Medicine (NLM) is seeking applications for a Training Center under the Network of the National Library of Medicine (NNLM). This initiative aims to enhance professional development for librarians, community engagement, and access to health information. By fostering partnerships and disseminating NIH resources, the NNLM will broaden its impact and improve public understanding of health data and information. The NTC will develop innovative training curricula and materials to meet diverse audience needs.