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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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32,483 Results based on applied filters

Mutual Self-Help Housing Technical Assistance Grants in Virginia

USDA: Rural Development (RD)
Federal Government
Virginia
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Virginia provide essential funding to organizations that assist low-income families in constructing their own homes through self-help projects. These grants enable recipients to offer technical support, recruit participants, and facilitate loan applications, ensuring that families can actively engage in building their future. This program fosters community involvement and empowers individuals, making homeownership achievable for very-low- and low-income households in rural areas.
Real Estate & Housing

Mutual Self-Help Housing Technical Assistance Grants in Wisconsin

USDA: Rural Development (RD)
Federal Government
Wisconsin
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Wisconsin provide essential funding for organizations to assist low-income families in constructing their own homes. This program empowers groups of very-low- and low-income individuals to work together, significantly reducing housing costs through shared labor. Eligible applicants include government non-profits and federally-recognized tribes, while ineligible costs include hiring contractors and purchasing materials. This initiative fosters community engagement and self-sufficiency in rural areas.
Real Estate & Housing

Mutual Self-Help Housing Technical Assistance Grants in Washington

USDA: Rural Development (RD)
Federal Government
Washington
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants program in Washington provides essential funding to qualified organizations that facilitate local self-help housing construction projects. This initiative empowers very-low- and low-income families to build their own homes in rural areas, fostering community engagement and resilience. Eligible organizations include non-profits and federally-recognized tribes, which can utilize funds for technical assistance, family recruitment, and supervisory support to ensure project success.
Real Estate & Housing

Mutual Self-Help Housing Technical Assistance Grants in Vermont

USDA: Rural Development (RD)
Federal Government
Vermont
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Vermont provide funding to qualified organizations to assist very-low- and low-income families in constructing their own homes through cooperative efforts. Recipients offer technical and supervisory support, helping families complete loan applications and enabling their participation in self-help housing projects. This initiative fosters community development while alleviating housing challenges in rural areas. Eligible applicants include government non-profits, federally-recognized tribes, and private non-profits.
Real Estate & Housing

Murco Foundation Grants

Community Foundation of North Central Wisconsin
Private
Marathon County, Wisconsin
US $1,000 - US $5,000
The Murco Foundation Grants, managed by the Community Foundation of North Central Wisconsin, focus on advancing education and the arts within the greater Wausau area and Marathon County. Established in 1992, the Foundation evaluates grant applications annually, prioritizing support for nonprofit organizations. However, they do not fund annual campaigns, operating expenses, or lobbying efforts. The grants aim to foster community enrichment and support for 501(C)(3) organizations.
Education Art & Culture

Harry & Helen Davidson Family Scholarship Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Harry & Helen Davidson Family Scholarship Fund

The Davidson Family Scholarship was established to honor the commitment to education and service to the Battle Creek community of Harry and Helen Davidson. Harry, who served as superintendent of the Battle Creek Public Schools for a number of years, who upon his retirement from the education field, became the first executive director of the Battle Creek Community Foundation. Much of Harry and Helen's work in this community can be exemplified today through development of our fine educational system, the growth of our Community Foundation, and a strong community value for the education of our young people.

Education - Higher Education

Mutual Self-Help Housing Technical Assistance Grants in Minnesota

USDA: Rural Development (RD)
Federal Government
Minnesota
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Minnesota provide essential funding to qualified organizations for managing self-help housing projects. This initiative supports very-low- and low-income families as they collaboratively build homes in rural areas, fostering community involvement and skill development. Eligible organizations include government non-profits and tribes, while grant funds can be utilized for technical assistance and family recruitment. This program plays a crucial role in addressing housing needs in underserved communities.
Real Estate & Housing

Mutual Self-Help Housing Technical Assistance Grants in Montana

USDA: Rural Development (RD)
Federal Government
Montana
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Montana support qualified organizations in facilitating local self-help housing projects. These grants enable very-low- and low-income families to construct their homes with guidance and technical assistance. Eligible areas can be verified through the USDA Eligibility Site, and funds can be utilized for recruiting families and providing necessary supervision and assistance throughout the housing construction process.
Real Estate & Housing

J. K. Stanford Memorial Award Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

J. K. Stanford Memorial Award Fund

Rose "Rossie" Miller, a passionate advocate for the community, and her family established this scholarship in memory of their loved one, J. K. Stanford, who was a talented auto mechanic. According to Rose, "my brother J.K. was so good of a mechanic, it seemed like he could simply listen to a car run and tell you what was wrong. He was a compassionate, kind-hearted person, who had a love of cars from an early age." Rose stated, "having received scholarship funds myself, I feel blessed to finally be able to give back to the community." The Stanford family witnessed the realities of not having certification and made a commitment to removing that barrier for others. This scholarship will benefit individuals obtaining certification as an auto or heavy equipment mechanic, an opportunity J.K. never had due to lack of funds. Recipients shall prove to be passionate about and persevere towards their educational goals while maintaining high academic standards.

Vocational & Trade Education

Mutual Self-Help Housing Technical Assistance Grants in Nebraska

USDA: Rural Development (RD)
Federal Government
Nebraska
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Nebraska provide funding to organizations that assist low-income families in constructing their own homes. This program encourages community collaboration, where participants contribute labor under the guidance of qualified organizations. Eligible applicants include government non-profits, federally-recognized tribes, and private non-profits. Funds support technical assistance, family recruitment, and loan application processes, while prohibiting expenses related to hiring construction labor or purchasing materials.
Real Estate & Housing

Muskegon County Medical Society Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Muskegon County Medical Society Scholarship

This scholarship has been made possible by the generosity of the members of the Muskegon County Medical Society, who established the Muskegon County Medical Society Scholarship of the Community Foundation for Muskegon County. This scholarship provides assistance to individuals pursuing projects or programs relating to health, science education and/or service.

Medical Education & Professional Training

Mutual Self-Help Housing Technical Assistance Grants in Nevada

USDA: Rural Development (RD)
Federal Government
Nevada
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Nevada support organizations in facilitating self-help housing projects for low-income families. By providing technical assistance, these grants enable participants to build their homes collaboratively, fostering community development. Eligible areas can be verified through the USDA Eligibility Site. The program emphasizes the importance of assisting families with loan applications and project participation, while prohibiting funding for direct construction work or purchasing materials.
Real Estate & Housing

Muskegon County Michigan State University Alumni Association Scholarship

Community Foundation for Muskegon County
Private
Ingham County, Michigan
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Muskegon County Michigan State University Alumni Association Scholarship

This scholarship has been made possible by the generosity of the Muskegon County MUS Alumni Association, which established the Muskegon County MUS Alumni Association Scholarship of the Muskegon County Community Foundation. This scholarship encourages Muskegon-area students who have graduated from Muskegon Community College to transfer to Michigan State University.

Education - Higher Education

Margaret A. Wright Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Margaret A. Wright Scholarship

This scholarship has been made possible by the generosity of Margaret Wright, who established the Margaret A. Wright Scholarship of the Community Foundation for Muskegon County. Margaret worked as a secretary for the Norge Corporation, the County of Muskegon and Muskegon Construction. She enjoyed sewing, ice skating and exercising at the Y. When she passed, she left a gift through her estate to create a scholarship fund that will support will support Muskegon County graduates that are pursuing a specific trade or skill.

Vocational & Trade Education

Muskegon Eagles / Monsignor Kehren Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Muskegon Eagles / Monsignor Kehren Scholarship

This scholarship has been made possible by the generosity of the Muskegon Eagles, Chapter 668, and Monsignor Kehren, who established the Muskegon Eagles Monsignor Kehren Scholarship of the Community Foundation for Muskegon County. Monsignor Kehren served St. Mary's Church in downtown Muskegon for many years. When he died, Chapter 668 of the Muskegon Eagles established this in his honor. The award is supported through an annual bowling tournament held by the Eagles. Thanks to their generosity, the spirit of Monsignor Kehren endures as part of the Muskegon community, granting the lasting gift of education to the youth of Muskegon County.

Education - Higher Education

Muskegon Surgical Associates Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Muskegon Surgical Associates Scholarship

This scholarship has been made possible by the generosity of the Muskegon Surgical Associates, P.C., who established the Muskegon Surgical Associates Scholarship of the Community Foundation for Muskegon County. The doctors in this surgical group wanted to fulfill their corporate responsibility and contribute back to the community. This scholarship award is for medical school students.

Medical Education & Professional Training

Mutual Self-Help Housing Technical Assistance Grants in New Hampshire

USDA: Rural Development (RD)
Federal Government
New Hampshire
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in New Hampshire support organizations in facilitating self-help housing projects for low-income families. This program enables families to construct their own homes in rural areas, providing essential technical assistance. Eligible applicants include government non-profits and federally recognized tribes, while funds cannot be used for purchasing materials or hiring external labor. This initiative promotes community collaboration and empowers families in the home-building process.
Real Estate & Housing

Mutual Self-Help Housing Technical Assistance Grants in New Mexico

USDA: Rural Development (RD)
Federal Government
New Mexico
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in New Mexico provide crucial funding to organizations that assist low-income families in constructing their own homes through cooperative efforts. Participants receive guidance and technical support as they work together, fostering community development and self-sufficiency. This program emphasizes the importance of empowering families in rural areas to build affordable housing while promoting economic stability and homeownership.
Real Estate & Housing

Mutual Self-Help Housing Technical Assistance Grants in New York

USDA: Rural Development (RD)
Federal Government
New York
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in New York provide essential funding to qualified organizations for local self-help housing projects. These grants enable very-low- and low-income families to construct their own homes with guidance and technical assistance. Eligible applicants include government and private non-profit organizations as well as federally recognized tribes. The program fosters community collaboration and provides families with the skills needed to manage their housing construction efforts effectively.
Real Estate & Housing

Mutual Self-Help Housing Technical Assistance Grants in North Dakota

USDA: Rural Development (RD)
Federal Government
North Dakota
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in North Dakota provide essential funding to qualified organizations that assist low-income families in constructing their own homes. These grants enable local organizations to offer technical and supervisory support throughout the construction process, fostering community and self-reliance. Eligible applicants include government non-profits and federally-recognized Tribes, ensuring that resources are directed towards those in need of housing assistance. This program ultimately aims to enhance rural housing initiatives.
Real Estate & Housing

Mutual Self-Help Housing Technical Assistance Grants in Ohio

USDA: Rural Development (RD)
Federal Government
Ohio
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Ohio support local organizations in assisting low-income families to construct their own homes in rural areas. Grant recipients provide essential technical and supervisory assistance, enabling families to engage in the building process. This program fosters community development and empowers participants through self-help housing initiatives, ensuring they gain valuable skills while improving their living conditions.
Real Estate & Housing

Drug Checking Technologies Program Grant

Wisconsin Department of Health Services
State/Local Government
Wisconsin
Unspecified amount

Drug Checking Technologies Program

The Division of Care and Treatment Services invites agencies currently participating in the DHS Naloxone Direct Program to apply to receive drug checking technologies at no cost for community distribution. The drug checking technologies available through this program include fentanyl test strips, fentanyl test strip kits, xylazine test strips, and xylazine test strip kits. 

Background

Drug checking technologies are an evidence-based method to prevent overdose deaths by educating people about the substances they are using.

Program overview

This DHS Drug Checking Technologies Program will provide:

  • Test strips packaged in boxes of 100.
  • Test strip kits individually packaged in a plastic zip bag with three fentanyl test strips or xylazine test strips, three mixing cups, three sterile waters, and three 10 mg scoops. 
Addiction & Substance Use Disorders

Mutual Self-Help Housing Technical Assistance Grants in North Carolina

USDA: Rural Development (RD)
Federal Government
North Carolina
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in North Carolina provide essential funding to organizations that aid low-income families in constructing their homes. Through local self-help projects, families work together under the guidance of grant recipients, who offer technical assistance. This initiative not only empowers communities but also promotes affordable housing in rural areas, ensuring that families have the support needed for successful home construction.
Real Estate & Housing

The David Lehr Award

American Society For Pharmacology And Experimental Therapeutics Inc
Private
Multnomah County, Oregon
Up to US $100,000
The David Lehr Award, funded by the American Society for Pharmacology and Experimental Therapeutics, supports preclinical and clinical research aimed at enhancing human health. Offering $50,000 annually for two years, this award encourages applications from experienced investigators needing funds for competitive renewals or preliminary data for new grants. Emphasizing diversity, the award aims to empower underrepresented researchers in the field. Awarded biennially, it fosters innovative pharmacologic approaches to advance healthcare.
Pharmacology

Mutual Self-Help Housing Technical Assistance Grants in Oregon

USDA: Rural Development (RD)
Federal Government
Oregon
Unspecified amount
The Mutual Self-Help Housing Technical Assistance Grants in Oregon provide crucial funding to organizations that assist low-income families in constructing their homes through cooperative effort. Grant recipients aid these families by offering technical and supervisory support, ensuring they can successfully build homes in rural areas. This initiative not only fosters community engagement but also empowers families by allowing them to take an active role in the construction process.
Real Estate & Housing

Nan Riekse Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Nan Riekse Scholarship

This scholarship has been made possible by the generosity of Nan Riekse, who established the Nan Riekse Scholarship of the Community Foundation for Muskegon County. Nan Riekse has a lofty dream; it is her desire to inspire. By establishing the Nan Riekse Scholarship and the Nan Riekse Donor Advised Funds, she has taken an important step toward realizing her dream. Her Scholarship will support non-traditional students attending Muskegon Community College who have financial need. Her scholarships will target adult women who may be attending school after raising their children or perhaps rebuilding their lives following a divorce. The Donor Advised Fund will be used to benefit local churches and a senior care center. Nan is an outstanding example of the "Power of One".

Adult Education

Ravenna Community Educational Foundation Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Ravenna Community Educational Foundation Scholarship

This scholarship has been made possible by the generosity of many people in the Ravenna Community, who established the Ravenna Community Educational Foundation Scholarship of the Community Foundation for Muskegon County. Dolores E. (Dee) Swanson gave the initial gift to start this back in December 2006. At that time it was a Build A Fund, but a gift from Rudolph and Ruth Lonnee put it over the top late in 2007. The Ravenna Community Educational Foundation intends to use it to enhance the quality of education through educational opportunities by generating and distributing financial and other resources for the benefit of the students and staff of the Ravenna Community Schools.

Education - Higher Education

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.