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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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32,499 Results based on applied filters

Tree Campus Higher Education Program: Hawaii

National Arbor Day Foundation
Private
Hawaii
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, initiated by the National Arbor Day Foundation, promotes sustainability and environmental stewardship in colleges across Hawaii. By participating, institutions can enhance campus beauty, improve mental health, and contribute to climate change mitigation through tree planting initiatives. The program establishes a framework for universities to achieve recognition while fostering community engagement and pride. Schools that meet specific standards can gain annual recognition, creating a greener and healthier campus environment.
Greening & Beautification

Tree Campus Higher Education Program: Georgia

National Arbor Day Foundation
Private
Georgia (US state)
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, led by the National Arbor Day Foundation, encourages colleges and universities to cultivate community forests. By meeting standards such as forming a Tree Advisory Committee and engaging in service-learning projects, institutions can achieve annual recognition, enhancing campus pride and environmental stewardship. This initiative promotes mental health through green spaces and reduces energy needs, making campuses healthier and more sustainable places for students and staff.
Greening & Beautification

Cyberinfrastructure for Sustained Scientific Innovation (358751)

National Science Foundation (NSF)
Federal Government
United States
US $600,000 - US $5,000,000
The Cyberinfrastructure for Sustained Scientific Innovation (CSSI) program by the National Science Foundation aims to provide flexible funding opportunities to address evolving needs in cyberinfrastructure. It supports various award classes, including Elements for small groups, Framework Implementations for larger interdisciplinary teams, and Transition to Sustainability for established CI projects. These initiatives focus on developing integrated CI services, ensuring sustainable impact, and promoting collaboration across scientific disciplines to enhance research and innovation.
Cyberinfrastructure

The Dayton Legal Heritage Foundation Fund Grant

The Dayton Foundation
Private
Darke County, Ohio, Greene County, Ohio +4 more
Unspecified amount
The Dayton Legal Heritage Foundation Fund Grant aims to enhance legal practices in the Greater Dayton area by funding nonprofit organizations that promote legal knowledge and justice awareness. Eligible applicants must be 501(c)(3) organizations with a proven track record, demonstrate diversity and collaboration, and address unmet community needs. The foundation prioritizes projects that optimize community resources, test innovative solutions, and encourage volunteer engagement. This grant represents a commitment to improving legal services for all citizens in the region.
Legal Services

Foundation for MCC - William H. Young Memorial Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

Community Foundation for Muskegon County

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

Our scholarship funds seek to empower and encourage Muskegon County residents to pursue their dreams, hone in their gifts, and give back to our community.

If you’re a high school or homeschooled senior, current college student, early college senior, or adult learner, the Community Foundation for Muskegon County may have a scholarship for you. We manage one of the largest scholarship programs in our area, with over $1 million committed to students in over 500 new and renewed scholarships awarded each year.

Foundation for MCC - William H. Young Memorial Scholarship

This scholarship has been made possible by an anonymous donor, who established the William H. Young Memorial Scholarship of the Foundation for Muskegon Community College of the Community Foundation for Muskegon County. This scholarship provides assistance to an associate degree-seeking student who demonstrates academic excellence based on either a high school or college academic record, with preference to students interested in the Social Service discipline.

Education - Higher Education

Foundation for MCC - Student Emergency Needs Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

Community Foundation for Muskegon County

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

Our scholarship funds seek to empower and encourage Muskegon County residents to pursue their dreams, hone in their gifts, and give back to our community.

If you’re a high school or homeschooled senior, current college student, early college senior, or adult learner, the Community Foundation for Muskegon County may have a scholarship for you. We manage one of the largest scholarship programs in our area, with over $1 million committed to students in over 500 new and renewed scholarships awarded each year.

Foundation for MCC - Student Emergency Needs Scholarship

This scholarship has been made possible by the generosity of the Foundation for Muskegon Community College, who established the Muskegon Community College Student Emergency Needs Scholarship of the Community Foundation for Muskegon County. This scholarship was established to provide scholarships to Muskegon, Ottawa or Newaygo County students.

Education - Higher Education

Carnegie Mellon University: Scholarly Project Funding

Carnegie Mellon University
Private
Allegheny County, Pennsylvania
US $750
The Carnegie Mellon University Scholarly Project Funding offers financial support for graduate students pursuing research essential to their degree programs. With grants of $750, it assists those whose resources are depleted. This funding, provided by the Graduate Student Assembly and the Office of the Provost, requires students to be enrolled during the funding period and to complete necessary application forms. Eligible expenses include books, travel, and research-related costs, enhancing the academic journey at CMU.
Education - Higher Education

Kenneth Erickson Auto Mechanic Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

Kenneth Erickson Auto Mechanic Scholarship

This scholarship has been made possible by the generosity of Marguerite Winter and Marilyn Lynn, who established the Kenneth Erickson Auto Mechanic Scholarship of the Community Foundation for Muskegon County. Kenneth Erickson was born at the end of the pre-car era. His father, a rural mail carrier, delivered mail by horse and buggy. When cars came along young Kenneth was fascinated by them and scavenged parts to build a yellow roadster, which he drove for several years. After a short stint at Continental Motors he decided to follow his passion and got a job as an auto mechanic. Eventually he opened his own business, Erickson's Garage, on Center Street in North Muskegon where he sold gas and repaired cars and trucks for over 40 years. In establishing the Kenneth I. Erickson Automobile Mechanic Scholarship, Ken's daughters, Marilyn Lynn and Marguerite Winter hope to support young people who would like to turn their passion for cars and motors into a life's work.

Vocational & Trade Education

Tree Campus Higher Education Program: Alabama

National Arbor Day Foundation
Private
Alabama
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, led by the National Arbor Day Foundation, empowers colleges to cultivate vibrant green spaces while enhancing student well-being. By meeting five essential standards, campuses can achieve recognition for their commitment to sustainability. This initiative not only fosters environmental stewardship but also promotes mental health and physical activity among students, creating a healthier campus environment. Join the movement to enhance your campus and community through tree planting and care.
Greening & Beautification

Tree Campus Higher Education Program: Alaska

National Arbor Day Foundation
Private
Alaska
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, initiated by the Arbor Day Foundation, empowers colleges and universities to enhance their community forests while achieving national recognition. By participating, institutions commit to comprehensive tree care and education, significantly benefiting both the environment and student well-being. This program not only promotes sustainability but also fosters a sense of pride within campus communities. Join us in cultivating greener campuses and nurturing the next generation's commitment to environmental stewardship.
Greening & Beautification

Carl J. Niedzial Memorial Scholarship

Connecticut Community Foundation
Private
United States
Unspecified amount
The Carl J. Niedzial Memorial Scholarship, established by the Connecticut Community Foundation in 1923, supports members of the CT State Police Credit Union and their immediate families, including grandchildren. As one of the largest scholarship providers in the Greater Waterbury and Litchfield Hills region, the foundation aims to help students achieve their college education dreams by addressing critical community issues and fostering equitable outcomes.
Academic Scholarship Programs

Aaron W. Howard Scholarship Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Battle Creek Community Foundation

Our Mission: The Battle Creek Community Foundation connects people, ideas, and resources to expand opportunity and create lasting community benefit for today and tomorrow.

Scholarships

Every Battle Creek area resident shall have the resources to access post-secondary education and training. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Aaron W. Howard Scholarship Fund

The Aaron W. Howard Scholarship Fund was established by the parents, family and friends of Aaron Howard. Pfc. Howard died in February 1991 while serving in the U.S. Army in the Persian Gulf War. He was a 1989 Lakeview High School graduate. There are no restrictions as to college to be attended or curriculum to be followed. To qualify, an applicant must be in need of financial assistance and must have demonstrated potential to succeed in the college curriculum to be pursued. Factors considered, in addition to financial need are character and citizenship, industry and effort and ability as indicated by test data and grades received to date in high school.

Education - Higher Education

William W. and Beverly I. Sutton Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount
The William W. and Beverly I. Sutton Scholarship, provided by the Community Foundation for Muskegon County, aims to empower Muskegon County residents to achieve their educational dreams. This scholarship is available to high school seniors, current college students, and adult learners. With over $1 million in scholarships awarded annually, it reflects the Foundation's commitment to fostering educational opportunities and community growth, ensuring that the legacy of Bill and Beverly Sutton continues to inspire future generations.
Education - Higher Education

Peruzzi Family Scholarship

Cherokee Nation Foundation
Association/Society
United States
Unspecified amount

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Scholarships

Cherokee Nation Foundation offers a diverse range of scholarships to help reverse the trend of rising student debt. Students may receive up to two CNF scholarships per academic year. All opportunities are reserved for Cherokee Nation citizens, unless otherwise noted in the description.

Peruzzi Family Scholarship

Applicant must be a graduating high school senior with a minimum 3.0 GPA and enroll full time in a four-year, higher education institution. This is a one-year scholarship reserved for Cherokee Nation citizens residing within the Cherokee Nation jurisdictional area.

Education - Higher Education

West Shore Cardiology Consultants, P.C. Scholarship

Community Foundation for Muskegon County
Private
United States
Unspecified amount

Community Foundation for Muskegon County

At the Community Foundation for Muskegon County, we work with donors, grantees, and advisors to address key community issues.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Scholarships

Our scholarship funds seek to empower and encourage Muskegon County residents to pursue their dreams, hone in their gifts, and give back to our community.

If you’re a high school or homeschooled senior, current college student, early college senior, or adult learner, the Community Foundation for Muskegon County may have a scholarship for you. We manage one of the largest scholarship programs in our area, with over $1 million committed to students in over 500 new and renewed scholarships awarded each year.

West Shore Cardiology Consultants, P.C. Scholarship

This scholarship has been made possible by the generosity of West Shore Cardiology Consultants, P.C., who established the West Shore Cardiology Consultants, P. C. Scholarship of the Community Foundation for Muskegon County. The five partners, Dr. Carl Gebuhr, Dr. Ralph Ryan, Dr. Mark Meengs, Dr. John Skallerup, and Dr. Gregory Bernath, felt they "...wanted to give something back to the community," and therefore chose a scholarship fund because of a strong commitment to education and its impact on an individual's success. Awards are for Muskegon County students with merit and financial need.

Education - Higher Education

African American Aspire to Greatness Scholarship

Delaware Community Foundation
Private
Delaware
US $1,000

African American Aspire to Greatness Scholarship

Awards:

  • One time award of $1,000.
Education - Higher Education

David Center for the American Revolution Postdoctoral Fellowship

American Philosophical Society
Association/Society
Philadelphia County, Pennsylvania
US $30,000
The David Center for the American Revolution offers a nine-month residential postdoctoral fellowship for graduate students focusing on the American Revolution and Founding Era (1750-1800). This fellowship, based at the American Philosophical Society Library & Museum, is designed for advanced Ph.D. candidates nearing dissertation completion. A stipend of $50,000 per year for two years is available. The fellowship emphasizes the importance of utilizing the extensive collections at the APS and encourages applicants from both U.S. and foreign backgrounds.
American History

John "Jack" and Jo Schils Scholarship Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

John "Jack" and Jo Schils Scholarship Fund

The John "Jack" and Jo Schils Scholarship Fund was established by the Schils family in 2020 as a memorial tribute to John "Jack" Schils, a multi-sports coach, athletic director, teacher, principal, father, grandfather, husband and friend to many. This fund supports students from the Battle Creek Public Schools District where Jack was employed from 1958 until his retirement in 1986.

Education - Higher Education

Rudisill Scholarship

Cherokee Nation Foundation
Association/Society
United States
Unspecified amount

Cherokee Nation Foundation

The Cherokee Nation Foundation is a nonprofit organization serving the Cherokee Nation, a federally recognized tribe of more than 470,000 citizens. Its mission is to provide educational opportunities to Cherokee students so they can reach their full potential. The Cherokee Nation Foundation is a tax-exempt charitable organization under Section 501(c)(3) of the Internal Revenue Code.

Scholarships

Cherokee Nation Foundation offers a diverse range of scholarships to help reverse the trend of rising student debt. Students may receive up to two CNF scholarships per academic year. All opportunities are reserved for Cherokee Nation citizens, unless otherwise noted in the description.

Rudisill Scholarship

Applicant must be an undergraduate student with a minimum 3.0 GPA majoring in education and in their full internship. This is a one-year scholarship reserved for Cherokee Nation citizens residing within the Cherokee Nation jurisdictional area.

Education - Higher Education

University of Tulsa/Cherokee Nation Foundation Scholarship

Cherokee Nation Foundation
Association/Society
Oklahoma
Unspecified amount
The University of Tulsa/Cherokee Nation Foundation Scholarship aims to support Cherokee Nation citizens pursuing higher education. Eligible applicants include undergraduate students and graduating high school seniors accepted to the University of Tulsa. This renewable scholarship lasts up to five years, contingent on maintaining a 3.0 GPA and good standing. A letter of reference is also required for consideration, reinforcing the foundation's commitment to fostering educational opportunities and reducing student debt among Cherokee students.
Education - Higher Education

Tree Campus Higher Education Program: New Jersey

National Arbor Day Foundation
Private
New Jersey
Unspecified amount in in-kind support
The Tree Campus Higher Education Program in New Jersey, managed by the Arbor Day Foundation, encourages colleges and universities to enhance their green spaces. This initiative helps campuses achieve national recognition for their commitment to environmental stewardship by meeting specific standards, such as establishing a Campus Tree Advisory Committee and a Tree Care Plan. Participating institutions benefit from improved campus aesthetics, mental health support for students, and a greater understanding of environmental responsibility.
Greening & Beautification

Lillian A. Jones Scholarship Fund

Battle Creek Community Foundation
Private
United States
Unspecified amount

Every Battle Creek area resident shall have the resources to access post-secondary education and training.

Your dreams matter — and we want to help you achieve them. Whether you’re a graduating high school senior, an adult returning to school, or a graduate student pursuing advanced education, we’re here to support you by opening doors to opportunity.

Beyond tuition, many funds support total cost of attendance — books, fees, equipment, and in some cases childcare or transportation.

Checks are made payable to the educational institution indicated on the follow-up and mailed directly to the educational institution. Checks are typically mailed in early August.

Lillian A. Jones Scholarship Fund

This fund was established in memory of Lillian A. Jones to support academic scholarships for graduate students who are Calhoun County residents. "Often times students finish their undergraduate degree and are in debt or just don't have the funds to continue on to higher degrees," said Lillian speaking about her fund, "There is a real need for these students too."

Education - Higher Education

CFNS: Women's Fund Grant

Community Foundation of the North State
Private
Shasta County, California
US $1,000 - US $10,000
The Community Foundation of the North State offers the Women's Fund Grant to support women's initiatives in Redding. Since 2008, this fund has empowered women and families through collaborative philanthropy, contributing to over $47 million in grants awarded by the foundation. Through relationship-building and integrity, the foundation aims to create a positive impact in Shasta, Siskiyou, and Tehama counties by fostering a culture of giving.
Women & Girl Services

Laurel High School Alumni Association Scholarships: Helen Kirk Deputy Ellis Scholarship

Delaware Community Foundation
Private
United States
Unspecified amount
The Laurel High School Alumni Association offers the Helen Kirk Deputy Ellis Scholarship for graduating seniors pursuing higher education. The Delaware Community Foundation, which awarded $850,000 in scholarships for the 2024-2025 school year, supports this initiative. Eligible students must have a minimum GPA of 2.50 and do not need to be alumni members. This scholarship aims to enhance educational opportunities for local students, fostering community growth and equity.
Education - Higher Education

Tree Campus Higher Education Program: New Hampshire

National Arbor Day Foundation
Private
New Hampshire
Unspecified amount in in-kind support
The Tree Campus Higher Education Program in New Hampshire, supported by the National Arbor Day Foundation, empowers colleges and universities to enhance their green spaces. By fostering community forestry, this initiative promotes environmental sustainability and mental well-being on campuses. Participating institutions can achieve national recognition by adhering to key standards, including establishing a Campus Tree Advisory Committee and a Tree Care Plan. This program not only beautifies campuses but also educates future generations on the importance of trees.
Greening & Beautification

Tree Campus Higher Education Program: Nevada

National Arbor Day Foundation
Private
Nevada
Unspecified amount in in-kind support
The Tree Campus Higher Education Program, facilitated by the National Arbor Day Foundation, empowers colleges and universities to cultivate community forests and enhance campus environments. By meeting specific standards, institutions can achieve annual recognition, promoting sustainability and mental well-being. The program underscores the importance of trees in reducing energy needs, absorbing carbon dioxide, and providing green spaces that benefit students and staff alike. Participation fosters pride and connects campuses to broader environmental initiatives.
Greening & Beautification

John C. Slater Predoctoral Fellowship in the History of Science, Technology, and Medicine

American Philosophical Society
Association/Society
Philadelphia County, Pennsylvania
US $30,000
The John C. Slater Predoctoral Fellowship, offered by the American Philosophical Society, supports advanced Ph.D. students in the history of science, technology, and medicine. This nine-month residential fellowship includes a $25,000 stipend and a $5,000 travel/research fund. Applicants must not be U.S. citizens or residents and do not receive visa sponsorship. The fellowship emphasizes timely project completion and the importance of access to research facilities in Philadelphia.
History Of Science

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.