Best Large Grants for Nonprofit Organizations

The Ralph C. Wilson, Jr. Legacy Funds offer grants to support youth sports initiatives in Western New York, focusing on increasing children's participation in sports. The foundation encourages community-driven projects that prioritize children's interests and promote active lifestyles. Eligible applicants include 501(c)(3) nonprofit organizations that aim to address objectives such as revitalizing local leagues and training coaches. These grants reflect Ralph C. Wilson, Jr.'s commitment to long-lasting community impact and innovation in youth sports.

The Youth Philanthropy Committee Grants, offered by the Hamilton Community Foundation, empower local teens to engage in philanthropy by making funding decisions. Comprising 20 students from various high schools, this initiative has been impactful for 15 years, awarding around $50,000 annually to support youth programs in the Hamilton area. The committee focuses on organizations that serve youth and emphasizes the importance of civic leadership and community involvement.

The Home Runs for Heroes Grants program, in collaboration with the Jersey Shore BlueClaws, aims to support veterans and military personnel through charitable donations tied to home runs hit during games. Each charity partner receives $1,000 per home run scored in their assigned inning, with a minimum donation guaranteed. The initiative emphasizes health, housing, quality of life, and youth education, while ensuring compliance with non-discrimination policies and eligibility criteria for non-profit organizations.

The California Casualty Thomas R. Brown Athletics Grant aims to support public middle and high school sports programs facing funding challenges due to budget cuts. Established by California Casualty, this grant provides financial assistance for purchasing equipment and covering travel costs for competitions. Eligible applicants must be active employees of public schools and members of affiliated education associations. Awards cannot be used for individual student recognition or fundraising projects.

Letha's Youth Outdoors Fund Grant provides financial support for field trips that connect youth groups in Indiana with nature. Ideal for educators, this grant fosters outdoor learning experiences, emphasizing the importance of native plants and their habitats. Since 2008, it has enabled over 15,000 youth to explore environmental education centers and parks, especially those with limited access to such opportunities. Grants range from $50 to $700, covering transport and educational activities.

The Tyson Undergraduate Fellows Program offers a unique 10-week summer experience for undergraduate students, providing hands-on engagement with environmental research at the Tyson Research Center. Participants collaborate with faculty and graduate mentors, attend professional development workshops, and gain exposure to diverse environmental fields. Each fellow receives a $6,000 stipend, along with potential housing assistance. This initiative aims to foster inclusivity and diversity within the research community, preparing students for future academic and professional endeavors.

The New York State Department of Agriculture and Markets is offering funding through the Companion Animal Capital Projects Fund to eligible not-for-profit shelters and humane societies. This grant supports capital projects that enhance the health and care of sheltered dogs and cats, such as construction, renovation, or expansion of facilities. Organizations can apply for funding for specific components of larger projects, ensuring better containment and welfare of animals.

The Housing for Everyone Grant Competition, part of the 2026 Initiative, aims to support eviction prevention in low-to moderate-income communities. This 20th annual initiative recognizes the destabilizing impact of eviction and displacement on families, which leads to job loss, school disruptions, and health issues. By funding innovative organizations, the competition seeks to provide stability for renters, enabling them to stay in their homes and communities.

We administer a number of scholarships, which range from the traditional academic and athletic awards to corporate and special circumstances offerings. Applying for a scholarship is free, so we invite you to spend some time finding opportunities for which you are a good fit.

Karen Schlosser Memorial Scholarship

The purpose of the fund is to provide an annual scholarship to a Marshall County resident attending Purdue University. 

The Karen Schlosser Memorial Scholarship is not renewable to previous recipients. 

We administer a number of scholarships, which range from the traditional academic and athletic awards to corporate and special circumstances offerings. These scholarships are open to all residents of Marshall County, as long as other requirements are met.

Applying for a scholarship is free, so we invite you to spend some time finding opportunities for which you are a good fit.

McKinnis Vocational Scholarship Fund

This scholarship will be awarded to one or more Marshall County graduating high school student(s) who will be attending a vocational trade or technical career school.

Enterprise Community Partners

Enterprise Community Partners is a national nonprofit that exists to make a good home possible for the millions of families without one. Home is where life happens, where plans are made, and futures begin. It is the foundation for dignity, health, education, wealth, and community. Yet rents keep going up, paychecks don’t keep pace, and good homes in strong neighborhoods are increasingly out of reach.

The system doesn’t work. It must be changed, and it must be changed by us.

Enterprise has the breadth, scale, and expertise to do it. We support community development organizations on the ground. We aggregate and invest billions to improve housing and strengthen communities across the U.S. We advance housing policy at every level of government. We build and manage communities ourselves. Everything we do is informed by the residents we serve.

Together with our partners, we focus on the greatest need — the massive shortage of affordable rental homes — to achieve three goals:

• Increase the supply of affordable homes
• Advance racial equity after decades of systematic racism in housing
• Support residents and strengthen communities to be resilient to the unpredictable, and make upward mobility possible

Since 1982, we have invested $92.0 billion and created 1.1 million homes across all 50 states, the District of Columbia, Puerto Rico, and the U.S. Virgin Islands. We do all this to make home and community places of pride, power, and belonging.

Legal Counsel in Administration of Blue Buffers Program

Enterprise Community Partners, Inc. ("Enterprise") was selected as a subrecipient of New York State Housing and Community Renewal to administer the Blue Buffers Program pursuant to a subaward. To fulfill its obligations, Enterprise formed a special purpose entity, Enterprise Assisted Properties, LLC (“EAP”).

Enterprise Assisted Properties ("EAP") has initiated a Request for Proposal (“RFP”) process to identify a legal representation panel which will be able to represent EAP in carrying out the New York State Blue Buffers Voluntary Risk Property Buyout Program.

Peter & Inez Schonveld Scholarship

This scholarship was established through a bequest from the estate of Inez Schonveld to provide scholarship assistance to graduating high school seniors and graduates of the Kalamazoo Public School District.

KZCF scholarships may be applied to any items under your school’s cost of attendance (COA). Each school has a different COA that may include items such as tuition, fees, housing, transportation, food, health insurance, etc. Scholarship payments are sent directly to your institution. 

This scholarship is a one-time award, meaning that it will not repeat in subsequent years. The money awarded can be applied to your education costs alongside other scholarships or funding that you may receive, and there are no necessary steps once funds are sent.

The Illuminate the Arts Grant (ITAG) aims to support Philadelphia's creative sector, particularly those historically underfunded. With $1.5M available, grants between $5,000 and $7,000 will be awarded to mid-size nonprofit arts organizations with budgets from $100,000 to $500,000. This initiative, established to aid recovery from the COVID-19 pandemic, focuses on enhancing public access to the arts and fostering cultural vibrancy in economically marginalized neighborhoods.

The Illuminate the Arts Grant (ITAG) supports small nonprofit arts organizations in Philadelphia with operating budgets under $100,000. A total of $1.5 million will be allocated to enhance creative practices and expand access to the arts in underserved neighborhoods. This initiative, established in 2021, seeks to uplift historically marginalized communities and foster Philadelphia's cultural vibrancy while ensuring equitable distribution of funds through collaboration with local advisory committees.

The Illuminate the Arts Grant (ITAG), administered by Creative Philadelphia, aims to uplift Philadelphia's creative sector through $1.5M in funding for individual artists and small organizations. Targeting historically underfunded communities, ITAG supports artistic practices while enhancing public access to the arts. Established post-COVID-19, this initiative fosters a vibrant cultural ecosystem and encourages applications from individual artists earning less than $66,850 annually, promoting inclusivity and resilience in the city's arts landscape.

The Olympic Club Foundation provides grants up to $25,000 to 501(c)(3) organizations that support youth sports programs in the Bay Area. The foundation prioritizes funding for programs that serve at-risk youth, focusing on developing leadership and teamwork skills through various sports. With an average grant size of $9,500, it aims to empower youth aged 5-18 to engage in athletic activities, fostering a healthy and active lifestyle.

The Evans Graham Preservation Award, established in 1998, supports the preservation of historic architecture in Michigan through $30,000 in annual funding. It honors David Evans, a noted preservation architect, and is awarded based on project merit by a jury. Eligible projects must be led by IRS-qualified nonprofits and involve an AIA Michigan architect. Applications open yearly on January 1st, with a submission deadline of March 17th, promoting creativity, community benefit, and preservation excellence.

Danial & Joeanna Smith Education Scholarship

The scholarship was established through a bequest from the estate of Danial and Joeanna Smith for the purpose of providing educational scholarships to permanent residents of Van Buren County and who are planning to pursue a bachelor's degree at a four-year college/university. Additional application materials are required for this scholarship.

KZCF scholarships may be applied to any items under your school’s cost of attendance (COA). Each school has a different COA that may include items such as tuition, fees, housing, transportation, food, health insurance, etc. Scholarship payments are sent directly to your institution.

This scholarship is a one-time award, meaning that it will not repeat in subsequent years. The money awarded can be applied to your education costs alongside other scholarships or funding that you may receive, and there are no necessary steps once funds are sent.

The Hudson Valley Animal Shelter Fund, established by Jean Rowe's generous bequest, aims to support nonprofit animal welfare agencies in the Hudson Valley indefinitely. Priority is given to organizations in Orange, Dutchess, Ulster, Putnam, Sullivan, and Rockland Counties that focus on rescuing and sheltering animals. Eligible applicants must qualify as 501(c)(3) nonprofits or be fiscally sponsored, and serve residents of Orange and Sullivan counties.

Ryan White Dental RFA

The Ryan White Part A Program at Public Health – Seattle & King County (PHSKC) funds the Lifelong Dental Program (LDP). LDP is a comprehensive oral health access program whose aim is to support low-income HIV-positive individuals living in King, Snohomish, and Island counties with access to oral health care services. The program covers the costs of dental procedures that are deemed medically necessary and time sensitive by participating dental providers and clinics.

Specific coverage limits for this particular Work are:

Commercial General Liability, to include Products and Completed Operations, in the amount of $1,000,000 combined single limit; $2,000,000 aggregate

Workers' Compensation and Stop-Gap Employer's Liability for a limit of $1,000,000

Professional Liability coverage of at least $1,000,000

Automobile Liability: If driving as part of the Scope of Work $1,000,000 combined single limit per accident for bodily injury and property damage. In the event that services delivered pursuant to this Contract involve the transportation of clients by Contractor personnel in Contractor-owned vehicles or non-owned vehicles, the limit  shall be no less than $3,000,000 combined single limit per accident for bodily injury and property damage.

Include Public Health – Seattle & King County 401 5th Ave, Ste. 1120, Seattle WA 98104, in the Certificate Holder box.

Provide an additional Insured endorsement to be included with the certificate of insurance, “CG 2010 11/85" or its equivalent is required which may include a blanket endorsement.

Total Amount of Federal Award: $ 1,987,222

Through this Request for Applications (RFA), PHSKC’s Ryan White Part A (RWPA) Program is seeking applications from dental providers/dental clinics interested in providing oral health services to low-income people living with HIV in the Seattle Transitional Grant Area (TGA) of King, Snohomish, and Island counties. PHSKC seeks to fund and contract with a varied group of providers capable of serving diverse communities and geographic areas within the TGA.

The dollar amount is based on the number of patients the provider’s practice can serve, provider specializations, location, and other factors. Providers will have this set amount of funds to use towards the oral health needs of LDP patients during the contract year.

The Plant Health Undergraduate Studentships, funded by the Royal Society of Biology, provide essential research opportunities for undergraduates in plant health. This program addresses skills gaps by pairing students with leading researchers for hands-on experience, while also supporting projects aligned with Defra's priorities. Students receive £400 per week for 8-10 weeks and participate in a mini-symposium to present their findings. The initiative aims to foster collaboration and innovation in plant health science through diverse research themes.

Brian Thiele Memorial Scholarship

This scholarship, established by family and friends in memory of Brian Thiele, provides financial assistance to students who exhibit characteristics similar to those for which Brian is so fondly remembered. This includes playing varsity and/or club soccer, achievement of personal and academic goals, overcoming obstacles to meet his goals, competitive spirit, leadership and a special caring for community. Additional application materials are required for this scholarship.

KZCF scholarships may be applied to any items under your school’s cost of attendance (COA). Each school has a different COA that may include items such as tuition, fees, housing, transportation, food, health insurance, etc. Scholarship payments are sent directly to your institution. 

This scholarship is a one-time award, meaning that it will not repeat in subsequent years. The money awarded can be applied to your education costs alongside other scholarships or funding that you may receive, and there are no necessary steps once funds are sent.

The Delta Dental of Illinois Foundation's Community Grants Program aims to enhance oral health among Illinois residents, particularly children. With over $5 million awarded over the past decade, the foundation prioritizes programs focusing on oral health education, access to care, and workforce development. Grants range from $1,000 to $20,000, and organizations can reapply yearly. Eligible applicants must be Illinois-based 501(c)(3) charities or governmental entities, addressing specific community needs in oral health.

Community Foundation of Northwest Mississippi

The Community Foundation of Northwest Mississippi manages 314 donor-established funds and has disbursed over $48 million to support more than 1,000 charitable organizations and activities recommended by its donors, as well as charitable programs established by the foundation. Established in 2002 with a generous grant from the Maddox Foundation, the Community Foundation is an independent 501(c)3 charitable organization. The Foundation serves Bolivar, Coahoma, DeSoto, Leflore, Marshall, Panola, Quitman, Sunflower, Tallahatchie, Tate, Tunica and Yalobusha counties. 

Shapoor Alexander Ghane Memorial Endowment

Shapoor Alexander Ghane was a Navy SEAL and to honor his memory this scholarship fund was established to benefit the children of Navy SEAL members who died in action. 

The Southern Equality Research Grant, offered by the Campaign for Southern Equality, aims to empower students and early career researchers to conduct crucial studies on LGBTQ+ issues in the South. With over a third of LGBTQ+ Americans residing in this region, there is a significant need for research to address legal protections and social inequities. This initiative seeks to elevate the voices and experiences of LGBTQ+ Southerners, fostering a deeper understanding of the policies affecting their lives.

The Nonprofit Security Grant Program (NSGP) in Alabama offers funding to nonprofit organizations at high risk of terrorist attacks. Managed by the Alabama Law Enforcement Agency, the program aims to enhance security through equipment upgrades, training, and collaboration among organizations and local agencies. Eligible applicants must be 501(c)(3) organizations demonstrating a clear risk. This initiative supports a proactive approach to safeguarding vulnerable communities against potential threats.

The Nonprofit Security Grant Program (NSGP) in Alaska supports nonprofit organizations at high risk of terrorist attacks by providing funding for physical security enhancements. With up to $1,650,000 available in 2025, individual awards may reach $200,000. This initiative aims to improve security posture, address capability gaps, and foster collaboration among community and government agencies, ensuring a comprehensive approach to emergency preparedness and resilience against evolving threats.