Best Large Grants for Nonprofit Organizations

The NATA Foundation, established in 1991, is dedicated to advancing the athletic training profession through research and education. It offers the Professional Grants Program to support exceptional research projects relevant to athletic training. With a funding limit of $50,000 over three years, the program encourages diverse proposals, ensuring that the primary or co-primary investigator is a BOC certified athletic trainer. This initiative aims to enhance the profession and benefit the broader physically active community.

The Amazon Literary Partnership Grant supports nonprofit organizations in the U.S. that empower diverse and marginalized writers. Since 2009, it has provided over $17 million to various literary groups, fostering emerging talent across genres. Eligible organizations must focus on developing writers, celebrating storytelling, and connecting them with audiences. By funding innovative initiatives, Amazon helps ensure that underrepresented voices are heard in the literary community, contributing to a rich and diverse narrative landscape.

The Anna C. Lawler Charitable Trust Grant focuses on supporting impactful projects in Venango County, PA. Eligible organizations must have 501(c)(3) status and demonstrate a commitment to community service. The trust prioritizes initiatives that provide measurable outcomes, collaborate with other entities, and address significant community needs without duplicating existing services. Organizations should have a minimum of three years of operational experience and present evidence of past successes to qualify for funding.

The Investigator Initiated Research Grant Program, offered by the Blue Cross Blue Shield of Michigan Foundation, supports doctoral-level researchers addressing critical health-related research gaps. Eligible applicants include primary investigators with medical or doctoral-level credentials based in Michigan's nonprofit hospitals and universities. This program emphasizes evidence-based research to improve health outcomes while ensuring effective resource utilization, thereby enhancing healthcare access and quality for Michigan residents.

The Colleen O'Toole Memorial Scholarship, established in 1992, honors Colleen O'Toole's dedication to Dayton Power and Light. It provides financial assistance to children of full-time AES Ohio employees, helping to cover tuition costs. Eligible applicants must maintain a minimum 3.0 GPA and demonstrate financial need. This scholarship not only supports educational aspirations but also commemorates a valued employee who served her community faithfully for over 25 years.

The Crossroads Fund: Seed Fund Grant supports organizations and groups in the Chicago Metropolitan area that promote social change. It focuses on collaborative, risk-taking, and strategic efforts that yield concrete community benefits. With a maximum grant of $15,000, it is open to 501(c)(3) organizations and those with fiscal sponsorship or bank accounts, prioritizing those with annual expenses under $500,000. This fund fosters diverse forms of activism, ensuring financial support for established and emerging community-based groups.

The Community Identity and Heritage Grant, administered by the Minnesota Humanities Center, allocates $6,299,000 to support projects that celebrate and teach the diverse cultures of Minnesota. This funding opportunity is open to individuals and organizations, with grants up to $300,000 available. It aims to enhance cultural heritage work for historically underrepresented communities, including Indigenous groups and recent immigrants. All funds must be utilized for new initiatives, ensuring the continuation and growth of Minnesota's rich cultural landscape.

The MTDPHHS School Health Grants aim to enhance health education in Montana schools by providing funding for projects that support school nurses, counselors, and educators. Available funding opportunities include training for asthma and diabetes education, assessing health policies, and facilitating CPR training. These grants are designed to foster safe and healthy learning environments for students and staff, ultimately promoting better health outcomes across the state.

The William “Bill” J. Brooks Memorial Fund Grant, established in 2021, aims to support community beautification projects in Shiawassee County. This grant honors the legacy of Bill Brooks, a dedicated community member and U.S. Navy veteran, who was passionate about enhancing his hometown of Owosso. Eligible non-profits can apply for funding to implement projects such as tree and flower planting, community gardens, and educational programs, fostering a vibrant and sustainable environment.

The Saints Arts Grants support theater, dance, music, and multi-disciplinary organizations in their artistic endeavors. Grants of up to $6,500 are available for projects taking place from June 1, 2025, to May 31, 2026. Eligible applicants must be 501(c)(3) organizations with at least three years of operation. Funded projects may include costumes, community outreach, and technical improvements, fostering diverse artistic expressions and community engagement.

The Nancy Armbrust Impact Award, presented by Schreiber Foods Foundation, honors women who significantly enhance community life. With a $5,000 grant for a nonprofit of the recipient's choice, the award empowers initiatives supporting women and girls. Recipients are recognized at the Women's Fund event around International Women's Day. This annual award celebrates Nancy Armbrust's legacy as a dedicated community leader, encouraging others to inspire and uplift women in their communities.

The Built to Play Skatepark Grants, funded by the Tony Hawk Foundation, aim to support the creation of free, public skateparks in low-income communities across Southeast Michigan and Western New York. With grants up to $250,000, the program emphasizes community involvement, environmental sustainability, and accessibility. It prioritizes projects designed by experienced contractors that engage local skaters in leadership roles. This initiative reflects a commitment to fostering healthy lifestyles and combating childhood obesity through active play.

The Urology Care Foundation International Student Humanitarian Grant supports a medical student to undertake humanitarian work in Trinidad and Tobago. This grant is aimed at AUA Medical Student members, focusing on improving public health and urologic care for this underserved population. The project lasts 6-8 weeks during the summer, typically between the first and second years of medical school, encouraging diversity among applicants from accredited medical schools.

The AUA Data Research Grant Program, funded by the American Urological Association Inc, aims to enhance urologic research by fostering a diverse group of dedicated professionals. This initiative focuses on bridging knowledge gaps in urology care and cultivating physician scientists through access to comprehensive data sources and mentorship from AUA Data Committee experts. By supporting innovative research, the program contributes significantly to the advancement of patient care in urology.

The American Urological Association Rising Stars in Urology Research Award supports physician-scientists in their journey to become independent researchers in urology. By providing supplemental salary support for up to five years, the program ensures awardees maintain protected research time while receiving competitive compensation. This initiative encourages promising researchers to compete for further funding and enhances their training in urologic research, ultimately advancing the field and improving patient care.

The Dr. Glenn Neil Love Medical Scholarship, established in 2014, provides annual financial assistance to individuals pursuing medical training and education. It aims to support nontraditional applicants currently employed in healthcare who demonstrate financial need and a commitment to advancing their skills. Priority is given to those seeking additional certifications or training to enhance their expertise in the medical field.

The CIS NAV Application Development Grant, administered by the Texas Education Agency, aims to enhance student support data management for Communities In Schools (CIS) affiliates throughout Texas. The grant will fund the creation of a secure, cloud-based application that facilitates real-time access to student data, improving operational efficiency and allowing CIS staff to concentrate on delivering direct support to students. This initiative will significantly reduce administrative burden and streamline processes.

Duke Energy Foundation

Duke Energy Foundation powers the vitality of the communities we serve by building vibrant economies; strengthening local resiliency; and promoting community opportunity.

More than $30 million in charitable grants each year drives impact and improvements in our communities. Additionally, Duke Energy volunteers donate nearly $4M worth of their time in nonprofit service.

Senior Economic Vibrancy

The Duke Energy Foundation seeks to support nonprofit organizations that strengthen stability for seniors, particularly families and individuals who are experiencing financial need in the communities we serve. The Foundation will invest $500,000 in organizations that help seniors age in place, maintain access to essential services and reduce financial strain through this grant opportunity.

Opportunity

Applications should demonstrate how investments will expand access to essential services for older adults and reduce financial strain associated with aging for families and individuals who are experiencing financial need in the communities served by Duke Energy. Examples of potential proposals include:

• Capacity to support critical home repair, safety modifications, or aging-in-place services.
• Strengthening organizations that help seniors access housing stability, food security, healthcare navigation, or benefits.
• Expanding organizational capacity to reach isolated older adults.
• Improving service coordination for seniors at risk of financial insecurity.

The American Urological Association's Research Scholar Award offers $40,000 annually for one or two years of mentored research training. This program aims to attract promising young investigators into urologic research, providing essential support to clinical and postdoctoral fellows within five years of completing their doctorate or residency and early career faculty within their first five years. This funding opportunity is crucial for fostering the next generation of urologic researchers.

The Beaufort Jasper Water & Sewer Authority Scholarship, established in 2024, offers financial support to students from Beaufort and Jasper Counties, South Carolina. This scholarship is both merit-based and need-based, aiming to assist deserving students in pursuing their post-secondary education. Funded by the Community Foundation of the Lowcountry, it reflects a commitment to fostering educational opportunities in the region.

The RPAC Fundraising Grants, offered by the National Association of Realtors, support state and local associations in organizing fundraising events aimed at boosting RPAC contributions. These grants require a fundraising goal three times the amount requested, ensuring tangible results. The initiative emphasizes developing detailed fundraising plans that comply with state laws regarding corporate treasury funds. This program is vital for enhancing RPAC participation and advancing property ownership advocacy.

We administer a number of scholarships, which range from the traditional academic and athletic awards to corporate and special circumstances offerings. These scholarships are open to all residents of Marshall County, as long as other requirements are met.

Applying for a scholarship is free, so we invite you to spend some time finding opportunities for which you are a good fit.

McKinnis Vocational Scholarship Fund

This scholarship will be awarded to one or more Marshall County graduating high school student(s) who will be attending a vocational trade or technical career school.

We administer a number of scholarships, which range from the traditional academic and athletic awards to corporate and special circumstances offerings. Applying for a scholarship is free, so we invite you to spend some time finding opportunities for which you are a good fit.

Karen Schlosser Memorial Scholarship

The purpose of the fund is to provide an annual scholarship to a Marshall County resident attending Purdue University. 

The Karen Schlosser Memorial Scholarship is not renewable to previous recipients. 

In 2025, the Community Foundation of Madison & Jefferson County awarded over $233,000 in scholarships to graduating seniors of the county’s public and private high schools. Nearly 50 different students earned money toward their college costs. Scholarships are available for a variety of applicants. Some are specific to schools, majors, need, or interests.

CFMJC scholarships may be used for tuition and related expenses like fees and required equipment at accredited colleges and universities. Room and board are not covered.

Dr. Harve E. & Joyce E. Rawson Endowment

Be enrolled at Franklin College in Franklin, Indiana. Contact Franklin College admission office.

The Urology Care Foundation's Health Equity Fellowship Grant aims to train early-career urologists dedicated to addressing healthcare disparities in marginalized communities. Over two years, fellows will engage in didactic education and hands-on advocacy projects, gaining skills to implement innovative solutions. The program emphasizes mentorship and collaboration with Temple University, providing a unique opportunity for urologists to enhance their understanding of urban bioethics and community engagement while receiving a recognized certification upon completion.

Joseph A. Catrambone Trade & Vocational Scholarship

Anyone pursuing a degree or certification in a trade or vocation.

Award:

• Full need is taken into account – awards amounts are based on need.

The NEDCorps 2.0 Immigrant Support Grant aims to alleviate poverty by fostering educational opportunities and financial self-sufficiency among immigrant families in northeast Dutchess County. With a total funding pool of $35,000 and individual grants up to $10,000, this initiative encourages nonprofits and community organizations to develop or enhance services for this growing population. The program prioritizes collaboration and aims to strengthen nonprofit infrastructure, ensuring impactful support for immigrants in the region.