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Best Large Grants for Nonprofit Organizations

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32,000+

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$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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32,241 Results based on applied filters

Kids In Business Merit Scholarship

Community Foundation Of New Jersey
Private
United States
Unspecified amount

Unless noted otherwise in the scholarship description and criteria statement, applicants can attend accredited schools of their choice within the United States.

CFNJ scholarships awards vary. On average, awards range from $500 to $2,500. However, the award could be larger based on the number of qualified applicants and the parameters set by donors who have established the funds. 

Kids In Business Merit Scholarship

This scholarship is awarded to individuals who are or have been associated with the Kids In Business program (Newark) who wish to further their education at an accredited educational institution.

Education - Higher Education

Peter Eisen Scholarship

Community Foundation Of New Jersey
Private
United States
US $500 - US $2,500

Unless noted otherwise in the scholarship description and criteria statement, applicants can attend accredited schools of their choice within the United States.

CFNJ scholarships awards vary. On average, awards range from $500 to $2,500. However, the award could be larger based on the number of qualified applicants and the parameters set by donors who have established the funds. 

Peter Eisen Scholarship

This scholarship is awarded to a graduating high school senior who has experienced the loss of a biological parent before the age of 18. Students must have achieved a cumulative 3.0 GPA or better. Applicants will be evaluated on academic performance, extracurricular activities, community service, work (paid or unpaid), and unmet financial need

Education - Higher Education

MEHAF: Discretionary Grants Program

Maine Health Access Foundation Inc
Private
Maine
Up to US $10,000
The Maine Health Access Foundation (MeHAF) offers discretionary grants to support small-scale projects that promote health access in Maine. Eligible organizations include 501(c)(3) entities and government bodies, with funding typically up to $5,000 for local projects and $10,000 for statewide initiatives. The program emphasizes innovative approaches that align with MeHAF's mission and requires tangible outcomes within one year. Note that only one grant is permitted per organization annually.
Health Care Access & Delivery

Siegel Family Scholarship

Community Foundation Of New Jersey
Private
United States
US $500 - US $2,500

Unless noted otherwise in the scholarship description and criteria statement, applicants can attend accredited schools of their choice within the United States.

CFNJ scholarships awards vary. On average, awards range from $500 to $2,500. However, the award could be larger based on the number of qualified applicants and the parameters set by donors who have established the funds. 

Siegel Family Scholarship

This scholarship is awarded to a graduating high school senior or recent graduate (1-2 years out of high school) from the greater Newark area. Preference will be given to students who have been actively involved with GlassRoots, Inc., or Big Brothers Big Sisters of Essex, Hudson & Union Counties. Students will be evaluated on academic performance (2.5 GPA or better), extracurricular activities, community service, work (paid or unpaid), and unmet financial need.

Education - Higher Education

Luling Foundation: Trade/Vocational Scholarship Grant

Luling Foundation
Private
Texas
US $1,000
The Luling Foundation offers a one-time $1,000 Trade/Vocational Scholarship Grant to support students in Caldwell, Gonzales, and Guadalupe Counties pursuing vocational training. Eligible applicants must be U.S. citizens or permanent residents, have a high school diploma, and maintain good academic and conduct records. This scholarship aims to promote education in trade skills, providing financial assistance for students beginning their vocational studies in the fall semester.
Vocational & Trade Education

Hosea Hall & Lilly Eason Vann Scholarship

Community Foundation of South Georgia
Private
United States
Unspecified amount

Who We Are

Founded in 1996, the Community Foundation of South Georgia is a 501(c)(3) nonprofit organization committed to making South Georgia a better place to live through effective philanthropy. We help individuals, families, nonprofit organizations and businesses establish and manage charitable funds that carry out their philanthropic interests. Serving a geographic area of 35 counties in South Georgia, we facilitate our donors’ charitable plans and goals by creating custom designed funds that meet their specific interests and ensure solid financial management and administration for each fund. 

Hosea Hall & Lilly Eason Vann Scholarship

For a graduating senior of a high school located in Thomas County, Georgia who has attained at least a 3.0 GPA in high school. The award is based on Academics, Financial Need, Leadership Qualities, Extracurricular Activities and Community Service.

Education - Higher Education

Huron Community Foundation

South Dakota Community Foundation
Private
Beadle County, South Dakota
US $500 - US $10,000
The Huron Community Foundation is dedicated to enhancing the quality of life in the Huron area by providing funding for programs that address basic needs during the COVID-19 pandemic. In 2020, the foundation prioritized support for food, shelter, and financial stability resources, aiming to assist those most affected by the crisis. Grants are not available for religious, political, or operational expenses, ensuring funds are directed to immediate community needs.
Basic Human Needs

Exploring Christian Practices Initiative

Lilly Endowment Inc
Private
United States
Up to US $2,500,000
The Exploring Christian Practices Initiative by Lilly Endowment aims to enhance access to settings that enable diverse individuals to engage in Christian practices. This initiative seeks to address spiritual interests, foster community connections, and support the growth of faith. By multiplying opportunities for exploration, it encourages meaningful participation in religious life and nurtures a deeper understanding of Christian traditions.
Christianity

Wake Forest Capacity Building Grant

Wake Forest University
Private
United States
Up to US $50,000
The Wake Forest Capacity Building Grant, part of the Educating Character Initiative, aims to enhance character education in U.S. higher education institutions. Established in 2023 with support from Lilly Endowment Inc., the initiative has already provided $35 million in grants to 146 institutions. In 2026, new grants will be awarded to colleges and universities focused on fostering moral, civic, and intellectual character among their faculty, staff, and students.
Civic Leadership Development

Institutional Impact Grants

Wake Forest University
Private
United States
US $100,000 - US $1,000,000
The Institutional Impact Grants by Wake Forest University aim to support U.S. colleges and universities in fostering moral, civic, and intellectual character among their community members. In 2026, these grants will empower institutions committed to character development for faculty, staff, and students, promoting a holistic educational environment. This initiative underscores the importance of character in education, aligning with the university's mission to cultivate ethical leaders.
Civic Leadership Development

Henry Luce Foundation: Luce Scholars Program

Henry Luce Foundation
Private
Cambodia, China +17 more
Unspecified amount
The Henry Luce Foundation's Luce Scholars Program offers immersive professional experiences in Asia for early-career leaders. Established in 1974, it aims to deepen understanding between the U.S. and Asian cultures. Open to U.S. citizens and permanent residents under 32 or recent graduates, the program provides stipends and language training to selected scholars. The foundation fosters diverse perspectives and adaptive leadership to promote global citizenship and mutual understanding through sustained engagement.
Cross-Cultural Understanding & Exchanges

General Library Grants

Tocker Foundation
Private
Texas
Unspecified amount
The Tocker Foundation offers General Library Grants aimed at enhancing library services and programs in rural Texas communities with populations of 12,000 or less. Grants support various initiatives including technology upgrades, collection development, and community outreach. Applications are reviewed biannually by a committee from the Texas Library Association, ensuring that funds are allocated to projects that significantly benefit local patrons. Libraries are encouraged to discuss their proposals in advance to align with funding priorities.
Library Services Library & Information Science

Library Travel Grants

Science History Institute
Private
Philadelphia County, Pennsylvania
Unspecified amount
The Science History Institute offers Library Travel Grants for researchers seeking to explore its vast collections. Grants of $1,000 per week support travel and accommodation for visits of up to two weeks. Eligible applicants must reside more than 75 miles from Philadelphia. This initiative fosters scholarly engagement with primary materials including rare books, manuscripts, and artifacts, contributing to a vibrant academic community.
History Of Science

DCCF: Women's Fund Grants

Decatur County Community Foundation Inc.
Private
Decatur County, Indiana
Unspecified amount
The DCCF: Women's Fund Grants provide essential support to initiatives that address issues affecting women and children in Decatur County. With a rolling deadline, these grants focus on empowering young girls through self-confidence, financial literacy, healthy lifestyles, and exposure to engineering fields. Funded by the Decatur County Community Foundation Inc., this initiative aims to create lasting change in the community by fostering the development of future leaders.
Women & Girl Services

Adult Education State Grants

Connecticut State Department of Education
State/Local Government
Connecticut
Unspecified amount
The Connecticut State Department of Education offers Adult Education State Grants to support programs for adult learners in Connecticut. These grants are based on eligible costs and are available to local education agencies that provide or facilitate adult education services. Eligible applicants can include school districts and educational service centers working collaboratively to enhance educational opportunities for adults. This initiative aims to improve access to education and foster lifelong learning in the community.
Adult Education

CFNA: Elk County Society for Special Services

Community Foundation of the Northern Alleghenies
Private
Elk County, Pennsylvania
US $1,000 - US $3,000
The CFNA: Elk County Society for Special Services offers funding to nonprofit organizations focused on enhancing Pre-K education programs within Elk County and surrounding areas. This grant aims to improve existing initiatives or develop new programs, ensuring support is directed toward community needs rather than individual requests. Eligible applicants must be tax-exempt 501(c)(3) organizations dedicated to serving diverse populations without discrimination.
Education - Preschool / Early Learning

CFNA: Women Who Care Grants

Community Foundation of the Northern Alleghenies
Private
Elk County, Pennsylvania
Up to US $5,000
Women Who Care Grants aim to empower women in philanthropy to strengthen communities by providing financial support for impactful projects. This initiative focuses on non-profit organizations serving Elk County and surrounding areas, prioritizing tax-exempt 501(c)(3) entities. Grants are awarded to programs that benefit all individuals, irrespective of race or creed, and do not fund personal projects or capital campaigns. The foundation emphasizes community needs over individual requests, ensuring a broad positive impact.
Family Services

Recreation, heritage Mini-grant

WeConservePA
Private
Crawford County, Pennsylvania, Venango County, Pennsylvania
Up to US $5,000

About Oil Region Alliance

The mission of the Oil Region Alliance of Business, Industry & Tourism is to manage the Oil Region National Heritage Area and to increase the prosperity of the Oil Region by enticing all people to live, work, learn and play in “the Valley that Changed the World” through the preservation, promotion, development, and support of historical, educational, natural, recreational, residential, commercial and industrial destinations.

Recreation, heritage Mini-grant

The Oil Region Alliance of Business, Industry and Tourism invites eligible entities to apply for the 2026 Outdoor Recreation and Heritage Mini-Grant Program to fund projects and programs that sustain, promote or enhance outdoor recreation offerings in the Oil Region National Heritage Area.

The historical significance of the Oil Region National Heritage Area (ORNHA) is the birthplace of the modern oil industry. ORNHA, which is managed by the ORA, includes all of Venango County, along with Titusville, Hydetown and Oil Creek Township in Crawford County.

Eligible entities may apply for more than one project so long as the total costs for the projects do not exceed $25,000 and the total grant request does not exceed $5,000.

A 50% match is required.

Outdoor Recreation

Publix Cares Scholarship

United Negro College Fund Inc
Private
Chatham County, Georgia, Chesterfield County, Virginia +6 more
Up to US $2,000

Publix Cares Scholarship

Publix Cares Scholarship was established by Publix Super Markets, Inc., a Florida corporation, in partnership with UNCF to provide scholarships to eligible students attending at one of the following selected institutions.

College/Universities

  • Bethune Cookman University
  • Florida Agricultural and Mechanical University
  • University of Central Florida
  • Benedict College
  • Clark Atlanta University
  • Savannah State University
  • Morehouse College
  • Spelman College
  • Virginia State University

Tennessee State UniversitySelected student will receive up to $2,000 need-based scholarship in the fall 2026.

Education - Higher Education

American Society of Biomechanics: Student Travel Awards

The American Society of Biomechanics
Private
Allegheny County, Pennsylvania
Unspecified amount in in-kind support
The American Society of Biomechanics offers Student Travel Awards to facilitate the attendance of student members at its annual meeting. These awards include complimentary registration for eligible students who have authored accepted abstracts for presentation. This initiative aims to promote the exchange of ideas among students and professionals in biomechanics and related fields, enhancing their academic and professional development through participation in this important event.
Biomechanics

Sample Foundation Grant

Sample Foundation
Private
Collier County, Florida, Montana
Unspecified amount
The Sample Foundation provides grants to non-profit organizations focused on health and social welfare, particularly for underserved populations in Montana and Collier County, Florida. It primarily funds capital projects and equipment purchases, emphasizing initiatives that align with its mission. Organizations must be tax-exempt and located within the specified geographic areas to be eligible. The foundation does not support scholarships, operating budgets, or religious entities.
Health & Medicine Human & Social Services

NAPB Borlaug Undergraduate Scholars

National Association of Plant Breeders (NAPB)
Association/Society
United States
Unspecified amount
The NAPB Borlaug Undergraduate Scholars program, established by the National Association of Plant Breeders, aims to cultivate future leaders in plant breeding. Open to undergraduates in relevant disciplines, the program provides mentorship opportunities and financial support for travel to the NAPB Annual Meeting. Those eligible must be current undergraduates and may not have received similar scholarships previously. This initiative fosters professional development and engagement in the field of plant improvement.
Plant Science

PennDOT Behavioral Highway Safety Grants: Community Traffic Safety Project (CTSP)

Pennsylvania Department of Transportation (PennDOT)
State/Local Government
Pennsylvania
Unspecified amount

PennDOT Behavioral Highway Safety Grants

PennDOT’s Behavioral Traffic Safety Unit offers traffic safety grants to support local communities and organizations working to make Pennsylvania’s roads safer. Eligible applicants include local governments, universities within the Pennsylvania State System of Higher Education, Pennsylvania state related universities, and nonprofit organizations.

These grants are funded through federal programs administered by the National Highway Traffic Safety Administration (NHTSA) under 23 U.S.C. §402 and §405. Funding follows the federal fiscal year, which runs from October 1 through September 30.

Grant opportunities focus on proven, data driven strategies that address the most urgent traffic safety challenges across the Commonwealth. Available funds are allocated using formulas based on crash data to ensure resources are directed where they can make the greatest impact.

Community Traffic Safety Project (CTSP)

Traffic safety educational outreach programs to schools and communities targeting local safety issues identified through data analysis. Provide support towards national and statewide enforcement mobilizations and other programs. Applicants for these grants must be a PA county government.

Automotive Safety

Literary Arts Fund Operating Grants

The Literary Arts Fund
Association/Society
United States
US $37,000 - US $50,000

Literary Arts Fund

Grants Overview

The Literary Arts Fund will award at least $50 million in grants to the nonprofit literary arts field over the next five years, concluding in 2031.

With a short timeline, the fund’s grantmaking has a strategic focus on the areas of the literary arts ecosystem where it determined it could have the greatest impact— that is: supporting independent U.S.-based literary arts nonprofits whose primary mission is directly serving adult writers of creative nonfiction, fiction, poetry, and hybrid works in making their artistic work and sharing it with readers outside of school and academic settings. Please review the fund’s full eligibility requirements to learn more.

General Operating Grants Applications 2026 Guide

Background

The Literary Arts Fund was established in 2025 to dramatically increase funding for and the visibility of the nonprofit literary arts field toward ensuring a healthy and more robust U.S. literary culture in support of creative writers. The fund will award at least $10 million in grants to the nonprofit literary arts field in each of the next five years, concluding in 2031. The first open call is for 2026 general operating grant applications.

Writing & Literature Nonprofit Growth & Development

San Antonio Area Foundation: Animal Services

San Antonio Area Foundation
Private
Atascosa County, Texas, Bandera County, Texas +6 more
Unspecified amount
The San Antonio Area Foundation’s Animal Services grant focuses on improving the lives of pets and people through community engagement and funding for nonprofits. With a history of reducing euthanasia rates from 50,000 annually to over 90% live release since 2016, the foundation has made significant strides in animal welfare. Eligible organizations must operate in designated Texas counties and possess 501(c)(3) status. The foundation does not fund endowments, capital campaigns, or individual-related expenses.
Animal Welfare - Domestic Animals & Pets

John P. Previti Memorial Foundation Grant

John P Previti Memorial Foundation
Private
Riverside County, California, San Bernardino County, California
US $1,000 - US $10,000
The John P. Previti Memorial Foundation Grant offers funding to non-profit organizations in Riverside and San Bernardino counties that focus on supporting at-risk youth. Grants, ranging from $1,000 to $10,000, are awarded to projects that provide essential services such as education, health, and basic needs. Eligible organizations must have 501(c)(3) status and align with the foundation's mission to uplift underprivileged youth and families in the community.
Youth Services

Crime Victim Compensation Program

Illinois Attorney General Office
State/Local Government
Illinois
Up to US $45,000

Office of the Illinois Attorney General

The Attorney General is the state's chief legal officer and is responsible for protecting the public interest of the state and its people.

The job of the Attorney General is to:

  • Advocate on behalf of all of the people of Illinois;
  • Legislate with members of the General Assembly for new laws; and
  • Litigate to ensure state laws are followed and respected.
  • The Attorney General provides services that cover a broad range of issues, reaching every corner of Illinois.

Crime Victims Compensation Program

A violent crime can have a lasting impact and can bring changes that one might not expect. The Office of the Attorney General led the way for legislation that created the Crime Victims Compensation Act. This law reserved resources to help those who lives were interrupted by a violent crime. This financial assistance could include offsetting costs related to:

  • Accessibility and Usability of Property
  • Crime-Scene Clean Up
  • Funeral/Burial Expenses
  • Loss of Earnings
  • Medical, Hospital and Dental Expenses
  • Mental Health Counseling Expenses
  • Relocation Costs
  • Replacement Costs
  • Tuition Expenses
Crime Victim Services

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.