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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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32,423 Results based on applied filters

Community Opportunity Fund: Opportunity Grant Focus

Boreal Waters Community Foundation
Private
Aitkin County, Minnesota, Ashland County, Wisconsin +11 more
US $25,000 - US $50,000
The Community Opportunity Fund, managed by Boreal Waters Community Foundation, empowers local organizations to enhance economic stability and independence in northern communities. The fund supports projects focused on affordable housing, job creation, and access to education. By fostering collaborative efforts, it aims to create lasting change in northeastern Minnesota and northwestern Wisconsin. Organizations led by marginalized communities are especially encouraged to apply, ensuring equitable opportunities for all.
Poverty Alleviation & Services Equitable & Affordable Housing Job Creation +2 more

Research and Development Grant Program

Ohio Water Development Authority (OWDA)
State/Local Government
Ohio
US $200,000
The Research and Development Grant Program by the Ohio Water Development Authority (OWDA) supports innovative projects in wastewater, water management, solid waste, and energy resource development. Eligible applicants include local government agencies and higher education institutions. Priority is given to proposals that enhance water quality, technology, equity, and resilience. Grants are contingent upon available funding, and applicants are advised to review the Participation Agreement before applying.
Waste Management Green Infrastructure Sanitation & Clean Drinking Water

Fair Housing Initiatives Program - Education and Outreach Initiative (362880)

US HUD: Office of Fair Housing and Equal Opportunity (FHEO)
Federal Government
American Samoa, Guam +4 more
US $175,000 - US $2,500,000
The Fair Housing Initiatives Program (FHIP), established by Congress in 1988, aims to fund organizations to combat discriminatory housing practices. The Education and Outreach Initiative (EOI) educates stakeholders about their rights under fair housing laws. Key components include the National Media Campaign, which promotes fair housing awareness nationally, and local programs that support community-based outreach. HUD oversees the process, ensuring compliance and monitoring of funded initiatives to enhance fair housing practices.
Basic Human Needs Real Estate & Housing Equitable & Affordable Housing +1 more

NMDA's Noxious Weed Management Grant

New Mexico Department of Agriculture
State/Local Government
New Mexico
Up to US $60,000

New Mexico Department of Agriculture

NMDA is a producer-consumer service and regulatory department responsible for various statutes legislated since its inception. NMDA’s mandate has changed over the years in response to changes in population, the needs of agribusiness, and technological advancements. NMDA remains committed to serving its constituents by periodically reviewing statutes and fee structures, as well as offering compliance assistance and education in an effort to maintain a safe and secure food supply, promote a fair marketplace, and secure our natural resources.

Noxious Weed Management Grant

Purpose

The New Mexico Department of Agriculture (NMDA) will award competitive grants to eligible applicants for projects that improve the state’s economy and environment by managing noxious weeds in New Mexico. The grants are funded through New Mexico’s Land of Enchantment Legacy Fund to achieve the purposes of the New Mexico Noxious Weed Management Act. 

Grant funds will be awarded for the following activities, but must include activities in at least one of the first three bullets bolded below to be considered for funding:

  • Surveying & Mapping
  • Early Detection and Rapid Response (EDRR)
  • Integrated Weed Management (On-the-Ground-Treatments)
  • Education/Outreach
  • Planning, Capacity Development, & Partnership Building
Botanical Conservation Invasive Species Control

Idaho Emergency Solutions Grants

Idaho Housing and Finance Association
State/Local Government
Idaho
Unspecified amount

The Emergency Shelter Grants program was established by the Homeless Housing Act of 1986 in response to the growing issue of homelessness in the United States. The Emergency Solutions Grants (ESG) program was created to replace the Emergency Shelter Grants program when the Homeless Emergency Assistance and Rapid Transition to Housing (HEARTH) Act was signed into law on May 20, 2009. The ESG Program is designed to support sheltered and unsheltered homeless persons, as well as those at risk of homelessness, by providing the services necessary to help those persons to regain stability quickly in permanent housing after experiencing a housing crisis and/or homelessness. 

Homelessness Services Supportive Housing & Shelters Equitable & Affordable Housing

NC Specialty Crop Block Grant Program

North Carolina Department of Agriculture & Consumer Services
State/Local Government
North Carolina
Up to US $200,000
The NC Specialty Crop Block Grant Program aims to enhance the competitiveness of specialty crops such as fruits, vegetables, and nursery crops. Administered by the North Carolina Department of Agriculture & Consumer Services, the program offers funding to support projects that improve food safety, research, and distribution efficiency. Eligible applicants include nonprofit organizations and government agencies. This initiative promotes sustainable practices and increases nutrition knowledge related to specialty crops, benefiting both producers and consumers.
Agricultural Crops Sustainable Agriculture & Agroecology Food Safety +2 more

Mumford & Keller Grant and Scholarship Program

Indiana Audubon Society Inc.
Private
United States
US $500 - US $5,000
The Mumford & Keller Grant and Scholarship Program, initiated by Indiana Audubon in 2010, offers financial support for projects focusing on natural resources and Indiana's birdlife. With grants ranging from $500 to $5,000, it aims to promote conservation, research, and education. Priority is given to initiatives targeting key species and habitats within Indiana. This program honors the legacy of Russell Mumford and Charles Keller, enhancing bird conservation efforts for future generations.
Ornithology Ornithological Conservation

Boren Scholarship

National Security Education Program
Federal Government
Africa, Asia +8 more
Up to US $25,000
The Boren Scholarship offers funding for U.S. undergraduate students to study critical languages abroad, enhancing their linguistic and cultural competencies. The program prioritizes students committed to public service in national security roles and supports immersive experiences in diverse regions, excluding Western Europe, Canada, Australia, and New Zealand. Awards vary based on the duration of study, with amounts reaching up to $25,000 for longer programs. This initiative fosters a deeper understanding of global cultures, vital for U.S. interests.
Food Security Environment Food Access & Hunger +3 more

Jim and Margie Fegley Orchestral String Scholarship Fund

Berks County Community Foundation
Private
Pennsylvania, United States
Unspecified amount
The Jim and Margie Fegley Orchestral String Scholarship Fund, established in 2013 by Marjorie Fegley, honors her late husband, James E. Fegley. This fund supports Berks County residents pursuing music education, particularly in orchestral strings. Applicants must maintain a GPA of 3.0 or higher and have participated in music programs. The Berks County Community Foundation manages this fund, which contributes significantly to the local arts and education landscape, fostering musical talent in the community.
Education - Higher Education Symphony / Orchestra Academic Scholarship Programs

Teton Springs Foundation Grant

Teton Springs Foundation
Private
Teton County, Idaho
Up to US $20,000
The Teton Springs Foundation Grant aims to enhance the quality of life in Teton Valley, Idaho, by providing financial support to nonprofits. This grant focuses on impactful projects in areas such as arts, education, health, recreation, and environmental conservation. Eligible organizations, including 501(c)(3) entities, can apply for funding to implement projects that yield measurable benefits. The foundation encourages collaboration and values partnerships to maximize community impact, ensuring a brighter future for the Teton Valley.
Art & Culture Education Human & Social Services +5 more

Emergency Solutions Grant (ESG) Program

Missouri Housing Development Commission
State/Local Government
Missouri
US $50,000 - US $100,000
The Emergency Solutions Grant (ESG) Program, offered by the Missouri Housing Development Commission, aims to provide essential housing assistance to homeless or nearly homeless individuals in Missouri. With an anticipated funding of up to $2,858,041, the program prioritizes activities like rapid re-housing, street outreach, and homelessness prevention. The competitive allocation process ensures funds are effectively used to support community initiatives that stabilize housing and prevent homelessness, aligning with HUD regulations.
Homelessness Services Equitable & Affordable Housing Supportive Housing & Shelters

ABC Conservation Awards

African Bird Club
Private
Africa
Up to £3,000
The ABC Conservation Awards, funded by the African Bird Club, provide grants of up to £3,000 for conservation projects in Africa. Open to residents and institutions, these awards support diverse initiatives such as bird monitoring, educational programs, and local club support. With over £600,000 awarded since 1996, ABC has funded more than 300 projects across 50 countries, fostering significant contributions to the conservation of African birds and habitats.
Ornithology Ornithological Conservation

Desert Conservation Program

California Wildlife Conservation Board
State/Local Government
Imperial County, California, Inyo County, California +6 more
Unspecified amount
The Desert Conservation Program, administered by the California Wildlife Conservation Board, aims to protect and restore the Mojave and Colorado Deserts, which are vital for biodiversity and cultural heritage. This initiative, established through the California Desert Conservation Act, focuses on land acquisition, restoration, and enhancing public access while also addressing climate resilience and improving air and water quality. Eligible projects include habitat restoration and scientific studies to support endangered species recovery.
Habitat & Ecosystem Restoration Climate Change Resilience & Equity Land / Habitat Conservation

Aging and Adult Services: Emergency Solutions Grant Program

North Carolina Department of Health and Human Services (NCDHHS)
State/Local Government
North Carolina
US $101,534 - US $505,030
The Aging and Adult Services: Emergency Solutions Grant Program aims to support non-profits and local government agencies in providing services for individuals and families experiencing homelessness or at risk of homelessness in North Carolina. Funded by the NC Department of Health and Human Services, this program focuses on crisis response and housing solutions to ensure homelessness is rare and brief. Activities include improving emergency shelters and offering essential services to those in need.
Homelessness Services Supportive Housing & Shelters Equitable & Affordable Housing

Upper Bucks Community Foundation Fund of LVCF

Lehigh Valley Community Foundation
Private
Bucks County, Pennsylvania
US $1,000 - US $5,000
The Upper Bucks Community Foundation Fund of LVCF, managed by the Lehigh Valley Community Foundation, supports nonprofit organizations in the Upper Bucks area, including Palisades, Pennridge, and Quakertown School Districts. It primarily funds projects in visual arts, performing arts, industrial arts, agricultural education, and conservation of rural life. This fund includes the Richard E. Gasser Fund and the Erwin J. and Gertrude K. Neusch Fund, which focus on enhancing community engagement and educational initiatives.
Science Emerging Technology Development Data Science & Digital Information Systems +8 more

Graduate Education Fund: Specialty Field Scholarships - AUKUS Scholarship

American Australian Association
Private
Australia, United States
Up to US $40,000
The AUKUS Scholarship, part of the Graduate Education Fund, supports American and Australian graduate students in security, technology, and diplomacy fields. Applicants must be citizens or permanent residents, with an offer from an accredited institution. The scholarship provides up to $40,000 for tuition, travel, and living expenses. Applications are due in March for Australia to USA and in September for USA to Australia. This initiative strengthens ties and promotes research in critical areas.
Domestic / Homeland Security Education - Higher Education International / Foreign Affairs +7 more

Stassel Education Scholarship

The Alaska Community Foundation
Private
United States
US $1,000

About Us

Overview

The Alaska Community Foundation connects people who care to the causes that make a difference and matter most to them. We encourage and nurture philanthropy through building and managing permanent endowments, convening stakeholders, working with partners to strengthen Alaskan communities, and providing donors with flexible giving options that are strategic to their philanthropic objectives. ACF also manages the Pick.Click.Give. program.

Mission

Inspiring the spirit of giving and connecting people, organizations, and causes to strengthen Alaska’s communities now and forever.

Vision

ACF envisions an Alaska where communities come together and have resources to thrive.

Stassel Education Scholarship Fund

The Stassel Fund was established in memory of Fred L. and Jean N. Stassel who came to Alaska on their honeymoon in 1949, making Anchorage their home for over 60 years until they passed away in 2017 and 2011 respectively. Here they raised 6 children, celebrated Alaska's statehood in 1959, survived the 1964 earthquake, and became active in the community and state. The Fund honors their dedication to education and service to others focusing on creating opportunities for all Alaskans, especially the vulnerable and most in need. Fred and Jean valued education, hard work, integrity, justice, respect, and care for all people. They were both educators, commercial fishers, and very active in social services through the United Methodist Church and other organizations. Fred was very influential in establishing the now-named Credit Union 1, and Jean was active with The League of Women Voters. They would be honored to know that deserving Alaskans were able to pursue their educational goals with the help of scholarships from the Stassel Education Fund.

Education - Higher Education STEM / STEAM Education Mathematics +7 more

Crawford Impact Initiative Grants

Crawford Heritage Community Foundation
Private
Crawford County, Pennsylvania
US $5,000 - US $25,000
The Crawford Impact Initiative Grants support non-profit organizations in Crawford County, providing a redesigned grant program that offers impactful funding opportunities. Organizations can apply for funding from both restricted and unrestricted funds, with a single application. Eligible applicants include tax-exempt nonprofits, governmental bodies, municipalities, and schools. The initiative emphasizes preventive and impactful projects addressing community needs, with a focus on collaboration and measurable outcomes.
Art & Culture Education Agriculture +11 more

Opioid Abatement Community Grants Program (OACGP): Short-Term Responsive Grants

Granite United Way
Private
New Hampshire
Up to US $15,000

What is Granite United Way?

Granite United Way is a nonprofit organization that makes strategic investments in our community to help people learn, earn, and be healthy. Our impact covers more than 85% of New Hampshire and Windsor County, Vermont. With the support of more than 22,000 donors and volunteers, we are working together to provide more than $14 million in support to over 400,000 individuals.

If you are concerned about issues in our community like homelessness, education gaps, and health disparities, you're not alone. Many of us want to make a meaningful difference, but aren't sure where to start.

At Granite United Way, we streamline that process by connecting your support to the most pressing issues in our community. We remove barriers and create opportunities for people to make a positive impact in our community. When you partner with us, you help meet critical needs and create a ripple effect of positive change throughout our community.

Opioid Abatement Community Grants Program (OACGP): Short-Term Responsive Grants

ranite United Way (GUW) administers the Opioid Abatement Community Grants Program (OACGP) on behalf of the New Hampshire Department of Health and Human Services and the Opioid Abatement Advisory Commission. Through this program, $10 million in settlement funds will be invested over two years to support community-based efforts that prevent, reduce, and address the harms of the opioid crisis across New Hampshire. OACGP supports programs, partnerships, and community-led work that strengthen prevention, treatment, recovery, and long-term wellbeing. Funding is available to nonprofit organizations, municipalities, school districts, and other eligible entities serving New Hampshire communities.

Grant Opportunities

  • Short-Term Responsive Grants:
    • Up to $15,000 for timely projects that address emerging needs, fill gaps, or strengthen community capacity.

Community Services Addiction & Substance Use Disorders Drug Use Disorder +1 more

NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed) (357511)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The NIAID Career Transition Award (K22) supports postdoctoral fellows transitioning to independent research positions, fostering their development into successful biomedical scientists. Key deadlines for applications span from February 2025 to June 2027, including specific dates for standard, renewal, and AIDS-related grants. This initiative, funded by the NIH, aims to enhance the career trajectory of emerging researchers in clinical and biomedical fields, ensuring a robust pipeline of innovative scientific talent.
Science Biology Medical Education & Professional Training +3 more

Barnabas McHenry Hudson River Valley Awards

Open Space Institute Land Trust Inc.
Private
Albany County, New York, Columbia County, New York +8 more
Up to US $6,000
The Barnabas McHenry Hudson River Valley Awards support exceptional young leaders in environmental conservation, historic preservation, and the arts. Awarded annually, these prestigious grants of up to $5,000 encourage students to engage in impactful projects with local nonprofits. Since 2007, the awards have honored the legacy of Barnabas McHenry, fostering a new generation of environmental advocates and cultural stewards dedicated to enhancing the Hudson Valley's unique resources.
Environmental Conservation Tourism Historic Preservation +3 more

Opioid Abatement Community Grants Program (OACGP): Multiyear Project Grants

Granite United Way
Private
New Hampshire
Up to US $75,000
Granite United Way administers the Opioid Abatement Community Grants Program (OACGP) to combat the opioid crisis in New Hampshire. This initiative allocates $10 million over two years to support community-based prevention, treatment, and recovery efforts. Eligible applicants include nonprofits, municipalities, and governmental entities dedicated to improving community well-being. The program aims to create lasting positive change by addressing critical health and social issues related to opioid abuse.
Community Services Addiction & Substance Use Disorders Drug Use Disorder +1 more

Craven County Community Foundation Grant

North Carolina Community Foundation Inc
Private
Craven County, North Carolina
US $500 - US $15,000
The Craven County Community Foundation Grant, established in 1991, is dedicated to enhancing local philanthropic efforts by supporting diverse nonprofit organizations in Craven County. Grants, typically ranging from $500 to $15,000, aim to address various community needs, including education, social justice, and health-related services. The foundation encourages proposals from tax-exempt public charities and local government units, fostering a collaborative approach to community development and enrichment.
Community Services Education Social Justice / Human Rights +5 more

DCLA Art Fund Grants

Staten Island Arts
Association/Society
Richmond County, New York
US $750 - US $7,000
The DCLA Art Fund Grants, offered by Staten Island Arts, support individual artists and collectives in creating culturally significant work. Open to all artistic disciplines, projects must include a public component. Emphasizing community engagement, the grants prioritize under-resourced disciplines and communities. With funding from the Greater New York Arts Development Fund, these grants aim to enhance cultural programming and education, fostering a vibrant arts scene on Staten Island.
Art & Culture Public / Community Art Humanities & Social Science +8 more

SCCF: Arts & Culture, Environment, Recreation, Community Development, Other Grants Cycle

Steuben County Community Foundation
Private
Steuben County, Indiana
US $3,000 - US $10,000
The SCCF grants aim to enhance artistic offerings, preserve Steuben County's natural resources, and improve recreational access. These grants support nonprofit organizations in their mission to uplift community quality of life through collaborative projects. Eligible projects include those that foster community gathering and address root causes of local issues. Ineligibility includes projects funded solely by government or those that do not serve the community. This initiative seeks to enrich both the cultural and environmental landscape of the region.
Art & Culture Recreation Environment +5 more

Winneshiek County Grants

Community Foundation of Northeast Iowa
Private
Winneshiek County, Iowa
US $3,000 - US $20,000
The Winneshiek County Community Foundation, part of the Community Foundation of Northeast Iowa, enhances the quality of life in Winneshiek County through grants that foster community development. By supporting arts, education, health, and environmental initiatives, the Foundation aims to empower local organizations and residents. Its focus on innovative and impactful projects ensures that funds create lasting benefits, while encouraging charitable giving and civic engagement in the region.
Community Services Art & Culture Education +7 more

Grundy County Grants

Community Foundation of Northeast Iowa
Private
Grundy County, Iowa
More than US $1,000
The Grundy County Community Foundation, part of the Community Foundation of Northeast Iowa, supports charitable projects to enhance life in Grundy County. It aims to foster vibrant communities through grants focused on arts, education, health, and community betterment. With strong emphasis on addressing local needs and sustainability, the Foundation prioritizes proposals that demonstrate community support and collaboration. Eligible organizations include 501(c)(3) nonprofits and government entities. Applications are welcomed for projects that benefit the residents of Grundy County.
Community Services Art & Culture Education +8 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.