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Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.
32,000+
Available grants
$8.25B
Total funding
$6K
Median grant
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Massachusetts Department of Elementary and Secondary Education
The Massachusetts Department of Elementary and Secondary Education provides leadership, oversight, funding, support, and accountability for the Commonwealth's approximately 400 school districts that educate close to 1 million public school children each year. We also oversees programs that serve 20,000 adult learners each year.
McKinney Vento Homeless Education and 21st Century Community Learning Centers — Family Engagement / Playful Learning Enhancement Grant
Purpose
The purpose of this federal targeted grant is to provide funding for districts to:
Priorities
For applicants for FISS:
For applicants for Playful Learning units:
Funding
Fund Use
For planning and implementation of Family Institute for Student SuccessFISS, funds may be used to:
For developing playful learning units, funds may be used to support stipends for educators to develop and implement playful learning, participate in trainings, team planning time, curriculum development, supplies and materials.
Samardzija-Gutesha Family Fund
The Field of Interest Fund reflects the Samardzija-Gutesha family’s values and commitment to giving back. It supports education and hands-on learning in farming, soil health, and water conservation, with a focus on FFA members and associate-level college students.
Scholarships benefit graduating seniors and second-year post-high school students who are originally from DeKalb County high schools with FFA programs.
The Samardzija-Gutesha Family Fund provides scholarships for post-high school students pursuing education in agriculture or conservation, as well as paid internships with local farmers, and conservation professionals. It also supports educational seminars on topics such as sustainable farming and agricultural business, and provides grants to local organizations that align with the donor’s values.
In its first year, the Fund awarded $65,000 in scholarships to eight graduating seniors from DeKalb, Genoa-Kingston, Indian Creek, Somonauk, and Sycamore high schools (pictured above). Each student attending a two-year college received a $5,000 scholarship, while students planning to attend a four-year university received $10,000.
Community Foundation of North Central Massachusetts
The Community Foundation of North Central Massachusetts, a non-profit public charity, is the leading community foundation in the region, managing charitable funds established by individuals, families, businesses and other non-profit organizations.
Career Readiness and Educational Access
This grant program focuses on preparing local residents for family-supporting jobs through career-related training, post-secondary education and other educational initiatives.
Objective: Advance the economic wellness of residents of North Central Massachusetts by increasing their access to education and effective career development initiatives.
Priority: During this funding cycle, priority will be given to programs that equip residents for family-sustaining employment, including vocational training and pathways to college
Empowering Monroe County Nonprofits
At the Community Foundation of Monroe County, we partner with organizations that drive meaningful change. From health and education to the environment, we provide the resources to help our local nonprofits thrive.
Monroe Health Endowment
The Community Foundation of Monroe County (CFMC) is seeking implementation-focused proposals for projects that directly advance Monroe County’s Community Health Improvement Plan (CHIP). We are investing in collaborative, community-driven solutions that produce measurable health outcomes for our residents.
Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations.
Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.
Brian Edkins Memorial Scholarship
Graduating senior from Cape Fear High School; South View High School (Cumberland County) or Scotland High School (Scotland County, NC).
Department of Behavioral Health
The Department of Behavioral Health provides prevention, intervention and treatment services and supports for children, youth and adults with mental and/or substance use disorders including emergency psychiatric care and community-based outpatient and residential services.
DBH serves eligible adults, children and youth and their families through a network of community based providers and unique government delivered services. It operates Saint Elizabeths Hospital—the District’s inpatient psychiatric facility.
Substance Use Disorder HIV Early Intervention Services
The Government of the District of Columbia, Department of Behavioral Health, Adult Services Division is soliciting applications certified substance use disorder (SUD) providers to conduct human immunodeficiency virus (HIV) early intervention services (EIS) to individuals seeking treatment services in the District of Columbia.
The goal of this funding is to prevent the spread of HIV by increasing awareness and education through counseling, screening/testing, data collection, linkage and referral to treatment service within the SUD/ Behavioral Health continuum of care provider network.
The DBH will fund grantees to implement HIV EIS to include the following four areas:
Audrey Davenport Scholarship
The Audrey Davenport Endowed Scholarship honors the remarkable legacy of Audrey Davenport, a visionary leader, mentor, and advocate for cultural inclusion in Northeast Georgia. This scholarship celebrates Davenport’s lifelong dedication to education, leadership, and service.
Audrey was raised in Cornelia, Georgia. After graduating from the Savannah College of Art and Design (SCAD) as a non-traditional student; with undergraduate and graduate degrees in architecture, she returned to Habersham County and became an outspoken advocate and community leader. She was the former Executive Director of the Habersham County Historical Society and current President and Curator of the Regional African American Museum of Northeast Georgia. She is widely recognized for preserving African American history in rural communities, her leadership in promoting multicultural awareness and mentoring young people throughout the region. A proud member of her community and a non-traditional graduate of the Savannah College of Art and Design, Davenport embodies perseverance, creativity, and community leadership.
The Scholarship supports Black/African American non-traditional female students who demonstrate resilience, leadership, and a commitment to community-building as a tool for positive change. This scholarship reduces financial barriers and helps students find their own path to serving their communities with purpose and pride. The 2026 scholarship will award a one-time award in the amount of $1,000.
About Us
Who We Are
The National Federation of the Blind is the oldest and largest nationwide organization of blind Americans. Founded in 1940 and currently headquartered in Baltimore, the NFB consists of affiliates, chapters, and divisions in all fifty states, Washington, DC, and Puerto Rico.
What We Do
Through our network of blind members, we coordinate many programs, services, and resources to defend the rights of blind Americans, provide information and support to blind children and adults, and build a community that creates a future full of opportunities.
What We Believe
We are the only organization that believes in the full capacity of blind people and has the power to transform our dreams into reality. We believe in blind people because we are blind people—from our democratically elected leaders to our diverse nationwide membership.
Scholarship Program
Thanks to our generous partners, there are thirty $10,000 merit-based scholarships currently available. All scholarships are awarded on the basis of academic excellence, community service, and leadership. The finalists are announced every spring. They then attend our national convention in July when the winners of each individual scholarship are selected.
The American Action Fund for Blind Children and Adults Scholarship
For more than 100 years the American Action Fund for Blind Children and Adults has strived to improve the lives of blind and Deafblind children and adults. Best known for annually producing and gifting Braille Calendars, sponsoring the free Braille books for blind children program, and administering the Braille Readers are Leaders contest, the American Action Fund leads in promoting Braille literacy. The American Action Fund is proud to award this scholarship to a deserving and talented blind person.
CDC Foundation
The CDC Foundation helps the Centers for Disease Control and Prevention (CDC) and the public health system save and improve lives by unleashing the power of partnerships to protect the health, safety and security of all communities, everywhere. The CDC Foundation is authorized by Congress to mobilize philanthropic partners, corporations, organizations and individuals to support the critical health protection mission of CDC and the public health system.
The CDC Foundation manages hundreds of programs each year aimed at protecting communities across the country from a variety of health threats—from chronic disease conditions including cardiovascular disease and cancer, to infectious diseases like malaria and HIV to emergency responses, such as Ebola and Zika.
Contractor for Implementation and Evaluation of Healthy Native Babies Project Materials
The CDC Foundation invites proposals from Tribes, Tribal Serving Organizations (TSOs), and Urban Indian Organizations (UIOs) [T/TSOs/UIOs] to implement and evaluate the implementation of the updated Healthy Native Babies Project (HNBP) materials within their service areas. This initiative aims to strengthen culturally relevant infant safe sleep education, increase community awareness and support Native families in reducing sleep related infant deaths. Selected T/TSOs/UIOs will adapt, disseminate and assess the use of HNBP materials in ways that reflect the cultural, linguistic and community-specific needs of the Native populations they serve.
Regional Conservation Partnership Program - Wisconsin
Benefits
RCPP encourages partners to join in efforts with producers to increase the restoration and sustainable use of soil, water, wildlife and related natural resources on regional or watershed scales. Through RCPP, NRCS and its partners help producers install and maintain conservation activities in selected project areas. Partners leverage RCPP funding in project areas and report on the benefits achieved. The Secretary of Agriculture may also designate up to eight critical conservation areas to focus RCPP assistance.
Funding
Funding for RCPP is allocated evenly to projects in two different categories, state/multi-state and critical conservation areas. Conservation program contracts and easement agreements are implemented through the Agricultural Conservation Easement Program (ACEP), Environmental Quality Incentives Program (EQIP), Conservation Stewardship Program (CSP) or the Healthy Forests Reserve Program (HFRP). NRCS may also utilize the authorities under the Watershed and Flood Prevention Program, other than the Watershed Rehabilitation Program, in the designated critical conservation areas.
The Regional Conservation Partnership Program brings together a wide array of local and national partners, including Indian tribes, nonprofit organizations, state and local governments, private industry, conservation districts, water districts, universities and many others. So far, more than 2,000 partners are engaged in locally-led conservation efforts through RCPP.
The most successful RCPP projects share four common characteristics: they innovate, leverage additional contributions, offer impactful solutions and engage more participants.
Community Foundations of the Hudson Valley
The Community Foundations of the Hudson Valley (CFHV) is a philanthropic community foundation that empowers individuals, families, businesses, and organizations to fulfill their charitable goals and strengthen communities across Dutchess, Putnam, and Ulster counties in New York. Through the establishment and stewardship of nearly 600 charitable funds totaling over $100 million in assets, CFHV has distributed hundreds of millions in grants and scholarships to address critical needs, including food insecurity, education, senior services, arts and culture, social services, environmental initiatives, and more. The Foundation works with donors to build lasting charitable legacies, offers leadership on community issues, and provides grants and scholarships that create both immediate relief and long-term positive impact throughout the Hudson Valley.
Marjorie A. Rifenburg Scholarship
This scholarship provides financial assistance with college expenses for individuals of Native American, American Indian, First Nation, or Indigenous descent. Eligible applicants include graduating seniors or past graduates of Dutchess County high schools, as well as students currently enrolled in Dutchess County colleges. Scholarship funds may be applied toward tuition at an accredited college, university, or trade school. Awards are one-time, payable directly to the school, with amounts of up to $4,000 and the number of awards varying each year. While the scholarship is not renewable, eligible students may reapply annually for each year of their undergraduate degree program.
Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.
Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?
Most grants are due in the first quarter.
What's the typical grant amount funded for Large Grants for Nonprofit Organizations?
Grants are most commonly $34,887.
Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.
Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.
Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.
To improve the chances of receiving large grants, nonprofits should:
Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.
Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.