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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

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$8.25B

Total funding

$6K

Median grant

33,000+ grants
$8.25B total
$6K median

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32,595 Results based on applied filters

Rio Grande Valley Policy Initiative

Hogg Foundation for Mental Health
State/Local Government
Brooks County, Texas, Cameron County, Texas +11 more
Up to US $70,000

Hogg Foundation for Mental Health

The Hogg Foundation for Mental Health was established in 1940 at The University of Texas at Austin by the children of Texas Governor James Hogg. For over a quarter of a century, the Hogg Foundation was guided by the passion and insight of the Governor’s daughter, Miss Ima Hogg, who actively promoted the foundation and encouraged its staff to pursue a bold, new vision. Today the Hogg Foundation is based at The University of Texas at Austin Steve Hicks School of Social Work and is funded through an endowment created by gifts from the Hogg family and managed by The University of Texas/Texas A&M Investment Management Company.

The Hogg Foundation is inspired by Ima Hogg’s vision for a Texas that supports and promotes mental health, resilience, and well-being. Miss Ima was ahead of her time in believing that mental health was just as important as physical health. She believed all people should have access to community-based resources to support mental well-being and live fulfilling lives, and she championed supports in everyday environments like schools, workplaces, places of worship, and homes.

Rio Grande Valley Policy Initiative

The Hogg Foundation for Mental Health invites eligible organizations in South Texas, especially those in the Rio Grande Valley (Cameron, Hidalgo, Starr, or Willacy Counties), to submit a proposal to support organizations engaged in local policy work, and to build local organizational capacity to enable sustained, strategic engagement in policy processes that advance mental wellness and address non-medical drivers of health. Each grantee partner will receive a three-year grant, with an award amount of up to $70,000 per year divided equally across the grant term. Each selected organization will have access to additional capacity building support through the University of Texas Rio Grande Valley’s Nonprofit Resource Center.

Initiative Goals

The VPI aims to achieve the following:

  • To support forward-looking strategies that empower local leaders
  • To expand participation in policymaking
  • To advance sustainable, community-driven solutions for the RGV and surrounding South Texas counties
Health Disparities & Social Determinants of Health Public Policy Mental Health & Psychiatric Diseases +4 more

Expansion of Transportation

Ohio Developmental Disabilities Council
State/Local Government
Ohio
US $100,000
The Ohio Developmental Disabilities Council aims to enhance transportation opportunities for individuals with developmental disabilities through funded projects. By expanding access to transportation, the council seeks to empower individuals with I/IDD to achieve independence and improve their quality of life. Two projects may receive $50,000 annually for five years, supporting diverse entities in Ohio. This initiative aligns with the council's mission to foster inclusion and community involvement for people with disabilities.
Disability Care & Services Children With Disabilities Intellectual / Developmental Disabilities +1 more

CBT: Youth Environmental Education Grant Program

Chesapeake Bay Trust
Private
Maryland
Up to US $10,000
The CBT Youth Environmental Education Grant Program aims to enhance youth engagement in environmental education in Maryland and surrounding areas. This program funds projects that allow students to explore local environmental issues through hands-on research, leading to actionable solutions. Grants support various initiatives, including outdoor investigations and educator training, with funds available up to $10,000 for selected projects. This initiative seeks to foster sustainable practices and environmental stewardship among young learners.
Freshwater Conservation Marine / Ocean Conservation Environmental Education +1 more

Business Attraction Prime Sites

Illinois Department of Commerce and Economic Opportunity (DCEO)
State/Local Government
Illinois
US $250,000 - US $25,000,000
The Business Attraction Prime Sites program, administered by the Illinois Department of Commerce and Economic Opportunity, aims to foster economic growth by supporting large-scale capital investments. This initiative targets companies relocating or expanding in Illinois, promoting job creation through diverse projects, including infrastructure development. Eligible applicants must commit to significant investments and job creation, contributing to a robust economic landscape in the state. The program aligns with strategic industry focuses outlined in the Illinois Economic Plan.
Economic Services & Development Job Creation Manufacturing Engineering +3 more

Virginia Adult Education Competitive Grant: Integrated English Literacy and Civics Education (IELCE)

Virginia Department of Education
State/Local Government
Virginia
US $50,000 - US $200,000

Virginia Department of Education

The Virginia Department of Education is the administrative agency for the commonwealth’s public schools. VDOE works in partnership with Virginia’s 132 school divisions to support and improve teaching and learning, set high expectations for all students, and promote student safety, wellbeing, and health.

Virginia Adult Education Competitive Grant Program

Purpose of WIOA Title II

In accordance with the Adult Education and Family Literacy Act (AEFLA), Title II of the Workforce Innovation and Opportunity Act (WIOA) of 2014, the purpose of this funding opportunity is to assist eligible providers in developing, implementing, and improving adult education and literacy programs to provide concurrent services that focus on the following:

  • Assist adults to become literate and obtain the knowledge and skills necessary for employment and economic self-sufficiency;
  • Assist adults who are parents or family members to obtain the education and skills that are necessary to become full partners in the educational development of their children, and lead to sustainable improvements in the economic opportunities for their family;
  • Assist adults in attaining a secondary school diploma and in the transition to postsecondary education and training, including through career pathways; and
  • Assist immigrants and other individuals who are English language learners in improving their reading, writing, speaking, and comprehension skills in English; mathematics skills; and acquiring an understanding of the American system of government, individual freedom, and the responsibilities of citizenship.

This grant funding includes opportunities 1.0 – Adult Education Regional Programs, 2.0 – Integrated English Literacy and Civics Education (IELCE), and 3.0 – Corrections Education and Other Institutionalized Individuals (C&I).

Integrated English Literacy and Civics Education (IELCE)

The IELCE program enables adult English Language Learners (ELL), including professionals with degrees and credentials in their native countries, to increase their proficiency in reading, writing, and comprehension skills in English and mathematics using standards-based instruction in order to understand and navigate American systems of government, individual freedom, and responsibilities of citizenship while preparing them for unsubsidized employment for in-demand industries that leads to a family-sustaining wage. All IELCE providers must offer at least one IET; not all IELCE participants must be enrolled in this component. 

IELCE Funds

IELCE grants are not allocated within the regional structure of adult education. Rather, they are competed and awarded based on demonstrated local need to develop education and training opportunities for local immigrant and refugee populations and the applicant’s past effectiveness in delivering such services. Eligible applicants for regional adult education providers, as well as other eligible applicants, including a consortium, may submit a single application for a local IELCE award.

Civic Engagement & Education Workforce Preparation & Job Readiness Adult Education +3 more

Garman Family Foundation Grant

Community Foundation for Greater Buffalo
Private
Allegany County, New York, Cattaraugus County, New York +6 more
Up to US $50,000
The Garman Family Foundation Grant, administered by the Community Foundation for Greater Buffalo, focuses on enhancing mental health, physical wellness, and education, particularly for women and children. With two annual cycles, it supports organizations in Western New York that hold a 501(c)(3) status. Applications are limited to one grant per year, prioritizing impactful initiatives. However, certain funding areas, such as higher education scholarships and political activities, are excluded from consideration.
Mental Health & Psychiatric Diseases Women & Girl Services Women's Health +5 more

Chronic Disease Screenings and Treatment Services Grant

Indiana Department of Health
State/Local Government
LaGrange County, Indiana
Unspecified amount

About

Mission

To promote, protect, and improve the health and safety of all Hoosiers.

Vision

Every Hoosier reaches optimal health regardless of where they live, learn, work, or play.

Chronic Disease Screenings and Treatment Services

County: LaGrange

The LaGrange County Health Department will be issuing funds for chronic disease screenings and treatment services. The screenings should be for individuals residing in LaGrange County who are lawful citizens of the United States, with treatment services offered to those meeting screening thresholds. (Core Public Health Services: Chronic Disease Prevention; Access & Linkage to Care)

Preventative Healthcare Chronic Illnesses Epidemiology & Public Health +3 more

VA Preservation Trust Fund Grant

Virginia Outdoors Foundation
Association/Society
Virginia
Up to US $200,000
The Virginia Outdoors Foundation (VOF) leads land conservation efforts in Virginia, safeguarding over 850,000 acres across 111 counties. The VA Preservation Trust Fund Grant, established in 1997, supports various projects aimed at protecting open spaces for agriculture, forestry, and recreation. With approximately $1.8 million available this round and no strict funding cap, VOF encourages applications for acquisitions, easements, and other initiatives that enhance environmental quality and community resources.
Land / Habitat Conservation Farmland Preservation Parks & Public Spaces +1 more

Massachusetts YouthBuild Coalition Program RFP

Massachusetts Department of Elementary and Secondary Education
State/Local Government
Massachusetts
Unspecified amount

Massachusetts Department of Elementary and Secondary Education

The Massachusetts Department of Elementary and Secondary Education provides leadership, oversight, funding, support, and accountability for the Commonwealth's approximately 400 school districts that educate close to 1 million public school children each year. We also oversees programs that serve 20,000 adult learners each year.

Massachusetts YouthBuild Coalition Program

Purpose

The purpose of this RFP is to provide funding to members of the Massachusetts YouthBuild Coalition, Inc., for comprehensive education, workforce training and skills development to youth as outlined in the FY2027 state budget.

Priorities

The Massachusetts YouthBuild Coalition provides young people between the ages of 16–24 the chance to turn their lives around through curriculum that combines academic instruction with workforce development training in which students spend one week in the classroom working toward their high school equivalency or diploma, followed by one week on a job site building or renovating affordable housing in their communities.

Workforce Preparation & Job Readiness Academic Success & Enrichment Youth Development & Leadership +1 more

Teens for Tomorrow Grant

Quad Cities Community Foundation
Private
Rock Island County, Illinois, Scott County, Illinois
Up to US $10,000
The Teens for Tomorrow Grant, offered by the Quad Cities Community Foundation, empowers high school students to support nonprofits in Rock Island County, IL, and Scott County, IA. With a total of $10,000 available each year, grants focus on critical community issues such as domestic violence, homelessness, immigration support, and food insecurity. Eligible 501(c)3 organizations can apply for operational and program support to enhance the well-being of local residents.
Domestic Violence Homelessness Services Immigrant Services +1 more

Y.O.U.T.H. Grants - Youth Opportunities Unlimited Throughout Hillsdale

Hillsdale County Community Foundation
Private
Hillsdale County, Michigan
Unspecified amount
The Y.O.U.T.H. Grants program, sponsored by the Hillsdale County Community Foundation, aims to enhance the quality of life for youth in Hillsdale County. It funds diverse projects in education, arts, and wellness that actively involve young people. Preference is given to initiatives that reach a broad audience, promote independence, and foster collaboration among organizations. This grant opportunity is open to tax-exempt entities and emphasizes youth participation in project planning and execution.
Youth Services Children’s Health & Pediatrics Children With Disabilities +2 more

RFP- Address The Opioid Overdose Crisis In Communities And Populations

Minnesota Department of Human Services Behavioral Health Administration
State/Local Government
Minnesota
US $350,000
The Minnesota Department of Human Services, through its Behavioral Health Administration (STATE), is seeking Proposals from qualified Responders to address the opioid overdose crisis in communities and populations that have been historically underserved and disproportionately impacted by opioid-related overdose deaths. 
Addiction & Substance Use Disorders Drug Use Disorder

TDHCA HOME Persons with Disabilities Program

Texas Department of Housing and Community Affairs
State/Local Government
Texas
Unspecified amount

The Texas Department of Housing and Community Affairs (the Department) announces a NOFA in HOME funds for Single-Family housing programs under the Persons with Disabilities (PWD) set-aside under a Reservation System. These funds will be made available to HOME Reservation System Participants with a current Reservation System Participation (RSP) Agreement. The following activity types are eligible uses of HOME funds awarded under this NOFA: (1) Homeowner Reconstruction Assistance (HRA) and (2) Tenant-Based Rental Assistance (TBRA).

Disability Care & Services Equitable & Affordable Housing Supportive Housing & Shelters

Valley County Community Foundation Grants

Valley County Community Foundation
Private
Valley County, Montana
US $500 - US $3,000
The Valley County Community Foundation (VCCF) is dedicated to enhancing community life through grant funding for projects that address various needs. By supporting nonprofit organizations in areas like arts, education, and economic development, VCCF ensures that donor contributions effectively tackle contemporary challenges. The foundation’s commitment to integrity and responsiveness fosters innovative solutions, making it a vital resource for community growth and sustainability in Valley County.
Art & Culture Education Natural Resources +3 more

Alabama State Council on the Arts Performing Arts Project Grant

Alabama State Council on the Arts
State/Local Government
Alabama
US $1,000 - US $10,000

Alabama State Council on the Arts

The mission of the Alabama State Council on the Arts is: To enhance the quality of life and economic vitality for all Alabamians by providing support for the state’s diverse and rich artistic resources.

Agency Goals:

  • Support excellence and professionalism in the arts.
  • Provide opportunities for high-quality arts education for every Alabama student and lifelong learner.
  • Provide opportunities for all Alabamians to experience the arts.
  • Identify, preserve, and present folk art traditions.
  • Promote diverse cultural artistic expressions.
  • Recognize and support the arts as a driver of economic vitality.
  • Increase public recognition and appreciation for the arts, arts organizations, and individual artists.

Projects

Project Grants are the most frequently applied for grant type, allowing a wide range of activities and events that result in positive arts experiences for the public. Project Grant proposals have included:

  • Festivals.
  • Performances.
  • Research and field surveys.
  • Exhibitions.
  • Author readings.
  • Juried competitions.
  • Theatrical productions.
  • Classes and workshops.
  • The creation or commissioning of works of art.
  • …And many other arts-oriented activities.

Performing Arts Art Education Arts / Culture Access & Participation +3 more

Greater Glendive Community Foundation Grant

Montana Community Foundation
Private
Dawson County, Montana
Unspecified amount
The Greater Glendive Community Foundation Grant aims to support projects that enhance the revitalization of downtown Glendive. Eligible proposals may focus on arts and culture, basic human needs, economic development, education, or natural resources and conservation. Funded by the Montana Community Foundation, this grant encourages innovative ideas that benefit the community and promote sustainable growth.
Art & Culture Basic Human Needs Economic Services & Development +3 more

Butte-Silver Bow Community Foundation Grant

Butte-Silver Bow Community Foundation
Private
Silver Bow County, Montana
Unspecified amount
The Butte-Silver Bow Community Foundation Grant offers annual funding of approximately $5,000 to support 501(c)(3) organizations in five key areas: arts and culture, basic human needs, economic development, education, and natural resources conservation. Committed to enhancing community welfare, the foundation values equality, dignity, and active participation in community life, striving to uphold the cultural and environmental resources of Butte-Silver Bow for current and future generations.
Art & Culture Basic Human Needs Economic Services & Development +3 more

Roy and Ida Eagle Foundation Grant

Roy and Ida Eagle Foundation
Private
Kern County, California, Santa Barbara County, California
Unspecified amount
The Roy and Ida Eagle Foundation, established in 2009, supports 501(c)(3) organizations focused on strengthening families and protecting wildlife in Northern Santa Barbara and Kern County. With a mission centered on family values and community improvement, the Foundation funds educational opportunities, health care services, and violence prevention programs. Grant applications are by invitation only, with a deadline for Letters of Inquiry set for April 30, 2025. This initiative aims to enhance community well-being through targeted charitable contributions.
Education Domestic Violence Child Abuse & Neglect +4 more

Traveling Office-Based Opioid Treatment (OBOT) Funding Opportunity

Idaho Department of Health and Welfare
State/Local Government
Idaho
Unspecified amount

The purpose of this program is to expand access to evidence-based treatment for OUD by supporting Traveling OBOT programs that deliver MOUD and related services in community-based, nontraditional settings. Funded programs will implement low-barrier, patient-centered care models that meet individuals where they are, particularly those in underserved and high-need communities, including people experiencing homelessness, justice-involved individuals, and residents of rural areas with limited access to treatment. This initiative seeks to improve timely access to care, increase retention in treatment, and reduce opioid-related morbidity and mortality in Idaho through flexible, community- based service delivery. Programs are also expected to integrate evidence-based interventions, behavioral health services, and linkages to social supports, while advancing health equity and addressing disparities in access to OUD treatment.

Addiction & Substance Use Disorders Drug Use Disorder

The Pat Landi Access Fund

Alloy Development Co Inc
Private
Butler County, Ohio, Warren County, Ohio
Up to US $10,000
The Pat Landi Access Fund aims to enhance local economic development in Butler and Warren Counties, Ohio, by investing in small business initiatives. With funding up to $10,000 per project and an annual budget of $50,000, the fund supports various economic-mission based activities, including direct loans and workforce development programs. By partnering with local organizations, the fund seeks to ensure sustainability and viability of small businesses, fostering a robust economic environment in the region.
Economic Services & Development Business Development Entrepreneurship +1 more

Colorado Sexual Health Initiative (CoSHI) Mini-Grants

Colorado Department of Human Services
State/Local Government
Colorado
US $10,000 - US $15,000

Colorado Department of Human Services

The Colorado Department of Human Services collaborates with partners in State and county governments, nonprofits, advocates, community residents, providers and many others to empower Coloradans to thrive through bold and innovative health and human services.

Colorado Sexual Health Initiative (CoSHI)

About CoSHI

The Colorado Sexual Health Initiative (CoSHI) is funded by a Personal Responsibility Education Program (PREP) grant via the Family Youth Services Bureau. CoSHI provides youth with age-appropriate, medically accurate, people-centered, and evidence-based strategies that are proven to help reduce the risk of untimely pregnancy and sexually transmitted infections (STIs).

CDHS received federal PREP funding in 2010 to develop a sexual health education program. Each year CDHS provides training, education, and funding to agencies and community based organizations serving young people in Colorado. These services are designed to help communities increase access to information on healthy relationships, consent, and other life skills topics, and are provided along with training for trusted adults who would like to increase their skills in answering questions about sensitive topics.

Sexual health education is important because research has shown that it helps youth:

  • Delay the initiation of sex (abstain)
  • Reduce the frequency of sex
  • Reduce the number of new partners
  • Reduce the incidence of unprotected sex

PREP funding gives Colorado communities the chance to coordinate initiatives and build upon state laws, Colorado Academic Health Education Content Standards, and local initiatives addressing sexual health education to create programming that fits their community needs. 

CoSHI Mini-Grants

Mini-grants support counties, and/or community based organizations interested in developing a sexual health education program for young people ages 10-19 (21 if pregnant or parenting) in Colorado. The target audience will include youth involved with systems of care (foster care, juvenile justice etc..), those who are experiencing homelessness or at risk of experiencing homelessness, youth who are survivors of human trafficking or at risk of human trafficking and those who are at high risk of untimely pregnancy, STIs or HIV. 

Reproductive Education Teen Parenthood Youth Services +1 more

DNRC Reclamation and Development Grants Program - Project Grant

Montana Department of Natural Resources & Conservation
State/Local Government
Montana
Up to US $500,000
The Reclamation and Development Grants Program (RDGP) Planning Grants support projects aimed at restoring environmental damage caused by non-renewable resource extraction. Funded by the state, these grants assist local governments in planning projects that repair, reclaim, and mitigate ecological harm, ensuring the sustainability of public resources. Grant amounts vary by project type, with funding available for reclamation, drought management, and hazard mitigation, reflecting a commitment to preserving Montana's natural heritage.
Environmental Conservation Freshwater Conservation Green Infrastructure +1 more

Grid Modernization Grant

New Mexico Energy Minerals and Natural Resources Department
State/Local Government
New Mexico
Unspecified amount

Notice of Funding Opportunity

Grid Modernization Grant Program

The State of New Mexico, Energy, Minerals and Natural Resources Department (EMNRD) Energy Conservation and Management Division (ECAM) is requesting applications pursuant to 17.9.588 New Mexico Administrative Code (NMAC), Grid Modernization Grant Program, from government entities for grid modernization projects to assist New Mexico in developing a modern electric grid that transitions the state to 100-percent zero-carbon electricity resources.

Grid modernization projects are those that make improvements to electric distribution or transmission infrastructure to accommodate or facilitate the integration of renewable electric generation resources with the electric distribution grid or otherwise enhance electric distribution or transmission grid reliability, grid security, demand response capability, customer service or energy efficiency or conservation.

Renewable/Sustainable Energy Energy Efficiency & Conservation Carbon / Greenhouse Gas Reduction

Real Skills for Youth Program: Inspiring Minds

State of Rhode Island Department of Labor and Training
State/Local Government
Providence County, Rhode Island
Unspecified amount

The Governor's Workforce Board

The Governor's Workforce Board (GWB) is the primary policy-making body on workforce development matters for the State of Rhode Island and has statutory responsibility and authority to plan, coordinate, fund, and evaluate education, employment, and training programs that increase the skills of the RI workers and address the workforce needs of RI businesses. The Board is housed at the Rhode Island Department of Labor and Training.

Real Skills for Youth

The goal of Real Skills for Youth is to prepare youth for success in college and/or career through meaningful career exposure and exploration of potential career paths and their on-ramps, skill-building with an emphasis on essential and professional skills and supported work-based learning experiences that allow participants to apply learning in a real-world setting. 

Real Skills for Youth programs often provide youth with initial exposure to the world of work, whether through a paid work experience, hands-on exposure to new careers, and practicing essential skills.

In FY26, the GWB allocated $2.8 million to the program to support partnerships consisting of schools, youth-serving organizations, employers, and others to develop and implement high-quality work-based learning and career exploration activities. This program is part of Rhode Island’s larger effort called Prepare RI.

Real Skills for Youth Partners and Programs: Inspiring Minds

What To Expect

  • Earn paid, hands-on experience in real school and education settings during the school year and summer
  • Build job skills and confidence through work readiness training and classroom support roles
  • Learn from mentor educators and receive individualized guidance and coaching
  • Explore careers in education and youth development through real-world experience

Career Pathways to Choose From

  • Education and Youth Development
  • Early Childhood
  • Elementary Teacher Assistants
  • (Substitute) Teachers 

You will have the opportunity to receive RIELDS training and get CPR & First Aid Certified!

Communities Served: Providence

Workforce Preparation & Job Readiness Career / College Preparation Youth Development & Leadership +1 more

Competitive Grants - Spring Cycle

Community Foundation of Greater Birmingham
Private
Blount County, Alabama, Jefferson County, Alabama +3 more
US $5,000 - US $75,000
The Community Foundation of Greater Birmingham offers competitive grants in various priority areas, focusing on equity, economic opportunity, and regional cooperation. Grants are available for strategic purposes, general operating support for emerging organizations, and established organizations. Eligible applicants include 501(c)(3) non-profits and government entities serving specific Alabama counties. The foundation aims to foster inclusive, thriving communities through collaborative efforts, addressing persistent poverty and promoting holistic growth and well-being.
Diversity, Equity & Inclusion Economic Rights, Justice, & Mobility Economic Services & Development +5 more

Real Skills for Youth Program: New England First (Rhode Island Region)

State of Rhode Island Department of Labor and Training
State/Local Government
Rhode Island
Unspecified amount

The Governor's Workforce Board

The Governor's Workforce Board (GWB) is the primary policy-making body on workforce development matters for the State of Rhode Island and has statutory responsibility and authority to plan, coordinate, fund, and evaluate education, employment, and training programs that increase the skills of the RI workers and address the workforce needs of RI businesses. The Board is housed at the Rhode Island Department of Labor and Training.

Real Skills for Youth

The goal of Real Skills for Youth is to prepare youth for success in college and/or career through meaningful career exposure and exploration of potential career paths and their on-ramps, skill-building with an emphasis on essential and professional skills and supported work-based learning experiences that allow participants to apply learning in a real-world setting. 

Real Skills for Youth programs often provide youth with initial exposure to the world of work, whether through a paid work experience, hands-on exposure to new careers, and practicing essential skills.

In FY26, the GWB allocated $2.8 million to the program to support partnerships consisting of schools, youth-serving organizations, employers, and others to develop and implement high-quality work-based learning and career exploration activities. This program is part of Rhode Island’s larger effort called Prepare RI.

Real Skills for Youth Partners and Programs: New England First (Rhode Island Region)

What To Expect

  • Learn robotics and coding through hands-on, team-based projects
  • Build STEM skills like problem-solving, teamwork, and critical thinking
  • Connect with industry professionals and explore future STEM careers
  • Compete and collaborate as part of a robotics team in a supportive, high-energy environment

Career Pathways to Choose From

  • Robotics
  • Engineering
  • STEM related fields

Communities Served: Statewide

Workforce Preparation & Job Readiness Career / College Preparation Youth Development & Leadership +1 more

TCEF: Texas Grassroots Mini-Grants

Texas Campaign for the Environment Fund
Private
Texas
Up to US $4,000
The Texas Campaign for the Environment Fund offers mini-grants up to $4,000 to grassroots groups addressing environmental issues, particularly in response to the February Deep Freeze. Applications are open to both formal and informal organizations, with a focus on community involvement and strategic action. Grants will prioritize applicants with annual budgets under $50,000. Evaluation criteria include project need, community participation, and the capacity to implement proposed activities.
Environmental Health Environmental Justice & Advocacy Environmental Stewardship +1 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.