Best Large Grants for Nonprofit Organizations

The Governor's Workforce Board

The Governor's Workforce Board (GWB) is the primary policy-making body on workforce development matters for the State of Rhode Island and has statutory responsibility and authority to plan, coordinate, fund, and evaluate education, employment, and training programs that increase the skills of the RI workers and address the workforce needs of RI businesses. The Board is housed at the Rhode Island Department of Labor and Training.

Real Skills for Youth

The goal of Real Skills for Youth is to prepare youth for success in college and/or career through meaningful career exposure and exploration of potential career paths and their on-ramps, skill-building with an emphasis on essential and professional skills and supported work-based learning experiences that allow participants to apply learning in a real-world setting. 

Real Skills for Youth programs often provide youth with initial exposure to the world of work, whether through a paid work experience, hands-on exposure to new careers, and practicing essential skills.

In FY26, the GWB allocated $2.8 million to the program to support partnerships consisting of schools, youth-serving organizations, employers, and others to develop and implement high-quality work-based learning and career exploration activities. This program is part of Rhode Island’s larger effort called Prepare RI.

Real Skills for Youth Partners and Programs: North Kingstown Chamber of Commerce

What To Expect

Career Exploration: The WindWinRI Program is an 80-hour career exploration experience designed for Rhode Island high school students to engage in hands-on, career-aligned learning in renewable energy and engineering. Through applied, project-based learning, industry-validated competitions, dual enrollment opportunities, and paid work-based learning experiences. Offered at interested high schools, students build technical and professional skills while designing, testing, and presenting energy systems. The program prepares students for both postsecondary and direct to career success and exposes them to high-demand career pathways in the clean energy and blue economy sectors.

Career Pathways to Choose From

• Welding
• Construction
• General Operations
• Finance
• Environmental Sciences
• Supply Chain Management
• Engineering

Communities Served: Warwick, West Warwick, Pawtucket, Exeter-West Greenwich, Coventry, Providence, Central Falls 

The Wisconsin Department of Health Services is offering funding to cover room and board costs for Medicaid members with an opioid use disorder or at risk for an overdose in residential treatment programs. This initiative aims to enhance access to essential services for individuals facing barriers due to non-reimbursable room and board expenses. With $2.75 million allocated from the National Prescription Opiate Litigation settlement, eligible Tribal nations and counties can apply to support affected individuals in their recovery journey.

The NH Wetland Mitigation Grant Program, managed by the New Hampshire Department of Environmental Services, aims to sustain aquatic resources. Through the Aquatic Resource Mitigation Fund, it offers an alternative to traditional mitigation by allowing In-Lieu Fee payments to support restoration and enhancement projects. The program pools funds from nine watersheds and provides competitive grants to ensure the long-term health and function of aquatic ecosystems, aligning with the federal goal of 'no net loss'.

Community Foundation of Mason County

The Community Foundation of Mason County – MCCF, Inc. is a county wide community foundation serving Mason County, WV. 

With support from our donors, the Foundation is happy to support community projects and programs that create opportunities for Mason County, its citizens and its communities.

Community Impact Grants

Community Impact Grants (CIG) are made in the fields of: Arts and Culture, Education, Health and Human Services, Recreation, Youth and Family Services, and Community and Economic Development. The Foundation focuses on: Capital and Equipment Projects, Program Development, Capacity Building, and Operating Support. 

Community Impact Grants: Capacity Building

Capacity Building Grants support projects that provide an organization with technical assistance and/or training to be able to more effectively meet their mission and/or provide services

Priority is given to projects that:  

• have significant impact on the people and communities served by the applicant organization;
• reach new audiences, expand existing programs or services, or respond to emerging needs;
• strengthen the organization’s capacity to deliver its services and meet community needs;
• are well-planned and can reasonably be achieved; 
• have a matching grant opportunity or seek a matching grant to leverage more funding;  
• have limited access to other sources of support; 
• serve the Mason County community.

Important Information for Grant Seekers

• Organizations may submit only one application per grant cycle. The only exception may be for organizations that have more than one physical site, with each site having its own board or governance structure. Such organizations must contact the Foundation before submitting more than one application to discuss eligibility.

• The total amount of funds requested generally may not exceed $10,000. Requests for more than $10,000 may be considered for projects that are highly collaborative or for projects that will have a significant impact on the community at large. As noted above, applicants must contact the Foundation prior to submitting a request in excess of $10,000.

• Organizations receiving a Community Grant in any grant cycle from the Foundation are not eligible for funding in the immediate next cycle.

• When the Foundation declines to support an application, the applicant may call the Foundation to discuss their proposal and to inquire about reapplying. After an application is declined once, the organization may re-submit the application one more time; if an application has been declined twice, then the organization may not submit another request for funding of the same project. 

Grant requests will be considered based on the applicant’s service area and on grant funds available.

The New Jersey Office of Faith Based Initiatives (OFBI) aims to enhance the capacity of faith and community-based organizations to address community issues. The program supports diverse projects including civic engagement, food security, and services for seniors, focusing on innovative approaches to create meaningful change. By fostering partnerships and providing resources, OFBI is committed to improving the quality of life for vulnerable populations and facilitating community-driven solutions.

The Walking Classroom Grant Program, offered by the Alliance for a Healthier Generation, enables classroom teachers in public schools to receive donated materials for their students. This innovative program promotes physical activity while maintaining instructional time through engaging podcasts. Ideal for grades 3-8, it enhances cognitive function and retention. Schools with the greatest need, both socioeconomically and academically, are prioritized, ensuring that all students can benefit from this unique educational approach.

The Community Impact Grants (CIG) by the Community Foundation of Mason County support the development of new services and programs to meet community needs. These grants prioritize projects in various fields, including arts, education, and health, with a focus on expanding existing services and reaching new audiences. Organizations applying must be located in Mason County, WV, and meet specific eligibility criteria. Grants typically do not exceed $10,000, ensuring impactful initiatives for local communities.

The Title III, Part A Web-based Resource Initiative Grant, administered by the Texas Education Agency, aims to enhance resources for emergent bilingual and immigrant students. This initiative will support professional development for local educational agency staff by providing interactive web-based guidance and resource tools. It is designed to strengthen program implementation and improve language development, ensuring better educational outcomes for over 5 million students in Texas.

The Floodplains by Design Grants program aims to enhance community resilience to flooding and restore vital habitats in Washington's river corridors. This initiative, led by the Washington Department of Ecology and various partners, supports projects that mitigate flood risks while preserving agriculture and promoting outdoor recreation. Eligible applicants include local governments and nonprofits, focusing on integrated floodplain management to address climate impacts and ensure sustainable development.

About The Community Foundation

The Community Foundation of Herkimer and Oneida Counties is a community-based social impact investor whose mission is to engage, invest, and lead—working toward a vision of community vibrancy with opportunity for all. Our team of experienced staff and dedicated trustees is committed to boldly leading and supporting transformational community investments. We channel charitable contributions from donors through nonprofit partners that are meeting current community needs and steward community resources responsibly to ensure greater capacity for the future.

Helpful Harvest Grant Round

The Community Foundation of Herkimer and Oneida Counties will host its Helpful Harvest Grant Round to help Herkimer and Oneida County nonprofits address food insecurity this holiday season. The Community Foundation is seeking applications from human service organizations whose primary operation is a food pantry, soup kitchen or shelter that provides pantry items or meals to residents.

The Puyallup-White River Watershed Small Grants program by Pierce County is designed to enhance environmental literacy and improve habitat and water quality across key watersheds. Open to various applicants including nonprofits and schools, it supports projects like invasive species removal and nature-based education. Successful proposals align with watershed councils' action agendas. The program promotes community involvement and sustainable practices, ensuring that local ecosystems thrive while fostering educational opportunities.

The Key Peninsula-Gig Harbor-Islands (KGI) Watershed Lu Winsor Environmental Grants support community-driven projects to enhance habitat and water quality. Managed by Pierce County in collaboration with local organizations, grants of up to $3,000 are available for initiatives such as invasive species removal and educational programs. Applications are open from March 3 to April 30, 2025, welcoming all eligible applicants including nonprofits, schools, and individuals.

The Steven Scott Quinn Scholarship Fund, established by the Stark Community Foundation, aims to support Stark County, Ohio residents pursuing higher education in fields such as culinary arts, hospitality, nursing, nutrition, physical therapy, and occupational therapy. This initiative reflects the Foundation's long-standing commitment to enhancing the community through philanthropy and addressing diverse educational needs since its inception in 1963.

Community Care Centers of Excellence (INFR8) 

The Community Care Centers of Excellence (CCCE) is a funding program by the California Institute for Regenerative Medicine (CIRM) that aims to expand access to innovative clinical trials and regenerative medicine treatments throughout designated counties in Northern California.

CCCEs will enhance patient access to regenerative medicine treatments by:

• Expanding the geographic reach of centers capable of conducting clinical trials and delivering approved therapies, and
• Developing a skilled workforce to support the delivery of regenerative medicine treatments and ensure broad accessibility to California patients.

This initiative addresses a key mandate of the California Stem Cell Research, Treatments, and Cures Initiative of 2020 (Proposition 14), emphasizing the importance of providing access to clinical trials and approved therapies resulting from CIRM-funded research.

Award Details

• Maximum Award Amount $9,000,000
• Maximum Award Duration Five years

The WDNR offers grants totaling $250,000 annually to friends groups and nonprofit conservation organizations to enhance facilities, develop recreation projects, and restore habitats on state properties. Eligible applicants must be nonprofit entities committed to conservation and have a written agreement with the DNR. Projects should focus on nature-based outdoor recreation and address specific unmet needs in alignment with DNR management plans. Grants can cover up to 50% of project costs, promoting sustainable environmental practices.

The Spartanburg County Foundation's Community Thanksgiving Grant fosters philanthropy and community engagement by supporting local nonprofits. Each year, a Thanksgiving service, hosted by various faith communities, collects donations that the Foundation matches up to $5,000. Eligible organizations must have annual budgets under $500,000 and serve specific areas, including family services and health. This initiative aims to enhance access to opportunities for underserved populations in Spartanburg County, ensuring direct benefits to local residents.

The COPIC Medical Foundation Grants aim to improve healthcare outcomes by funding programs that enhance patient safety and reduce medical errors. With over $10 million awarded since its inception in 1991, the foundation focuses on scalable solutions to address healthcare fragmentation. This final grant cycle emphasizes innovative approaches that can be replicated across the healthcare community. Organizations must be 501(c)(3) certified or have a fiduciary partner to qualify for funding.

The Arts & Social Cohesion Grant, funded by the Vermont Community Foundation, aims to enhance community belonging through diverse artistic projects. Grants up to $10,000 will support initiatives like mural projects, artist residencies, and public performances that foster collaboration and engagement. The program prioritizes projects that connect marginalized voices and create inclusive environments, encouraging social interaction and community cohesion. This grant is designed for nonprofits and community groups focused on impactful artistic endeavors.

Nebraska Blue Foundation

Empower. Support. Uplift.

Nebraskans serving Nebraskans – It’s who we are and what we have done for more than 85 years at Blue Cross and Blue Shield of Nebraska (BCBSNE).

Our customers and employees have lived, worked and played here for generations, and we’re proud to be part of the Cornhusker State’s history. As a local business, we are also invested in the state’s next chapter because your communities are our communities. We share in the successes and challenges facing our state and are dedicated to helping Nebraskans thrive by serving as a champion for health and well-being.  

The Nebraska Blue Foundation, founded in 2024, powers BCBSNE’s philanthropic initiatives. Through the foundation, we support programs improving the health and well-being of Nebraskans and the economic vitality of our state.

The foundation builds on BCBSNE’s rich legacy of uplifting all who call Nebraska home.

Fall Grant Cycle

Overview

For more than 85 years, Blue Cross and Blue Shield of Nebraska (BCBSNE) has been a champion for the health and well-being of our members and the communities we serve. Founded in 2024, the Nebraska Blue Foundation now allows us to concentrate our efforts into pockets of our community that need to be uplifted the most.

The foundation has four priority areas:

The Nebraska Blue Foundation is particularly interested in supporting innovation and pilot projects. As a new foundation, our approach is to be catalytic with our grants – primarily investing in new ideas or programs that could meet a specific need with a one-time investment.

The Iowa Department of Natural Resources (DNR) offers the Conservation Education Program (CEP) to enhance environmental awareness and stewardship among Iowa citizens. With $350,000 available, eligible applicants include educational institutions and organizations. The program aims to support effective curricula and educator stipends, promoting sustainable practices. Grant recipients must maintain detailed records and submit progress reports. Preference will be given to projects that emphasize conservation stewardship and incorporate educational materials across multiple disciplines.

About Samba RecoverySamba Recovery is dedicated to empowering individuals recovering from alcoholism and drug addiction by restoring confidence and fostering resilience. Through a foundation of compassion, support, and holistic care, we guide individuals toward renewed health and wellness, meaningful relationships, and the discovery of their inner strengths—assisting them to achieve their fullest potential.Hope for Addiction ScholarshipSamba Recovery’s Hope for Addiction Scholarship is an annual $1,000 award dedicated to encouraging more young people to join the fight against addiction by pursuing degrees that directly support individuals and families affected by substance use disorders.

We welcome applications from all eligible students, with special encouragement for those who are in recovery themselves or who have been impacted by addiction within their families.Application requirements:

• Proof of college enrollment or acceptance
• Pursuing a degree with the goal of working with individuals and/or families impacted by addiction
• Completed application form
• An original 500 to 1000 word essay on how you are planning to use your degree to help individuals and families struggling with addiction, and why helping those affected by substance use disorder is important to you

The Laura Turner Dugas Fund for Allen County aims to enhance the community's quality of life by funding programs that address crucial needs such as education, health services, the arts, public recreation, and beautification. This private fund supports 501(c)(3) organizations based in Allen County, prioritizing projects that demonstrate sustainability and measurable outcomes. The fund seeks to build a legacy for future generations, promoting philanthropic giving and community engagement.

The Community Foundation of South Central Kentucky supports philanthropic initiatives aiming to enhance community welfare through grants. Focused on lasting impact, the foundation funds projects in five key areas: education, health and human services, the arts, public recreation, and beautification. Eligible applicants include 501(c)(3) organizations within the BRADD area of Kentucky. The foundation prioritizes projects that address community needs while excluding funding for individuals, capital campaigns, endowments, and general operating expenses.

The BRCFSC Community Grants, offered by the Blue River Community Foundation, support projects in Art & Culture, Health, Education, and Social Services for Shelby County residents. These grants are funded through various unrestricted family and interest funds, promoting initiatives that address beautification, youth support, and disability services. Eligible organizations must demonstrate sound accounting practices, while projects already in progress or focused on travel or political campaigns are ineligible. This competitive grant cycle encourages community-driven development.

The Women’s Fund Grants Program, conducted by the Community Foundation Alliance, Inc., supports nonprofit organizations serving Vanderburgh County. This year's cycle includes two Impact Grants of $50,000 each for programs and projects, alongside four additional grants of $20,000 for finalists. Eligible organizations must demonstrate long-term planning, financial sustainability, and a commitment to gender equity. Applications will be accepted from 501(c)(3) tax-exempt entities and governmental agencies.

The Cass County Opioid Settlement Funds provide crucial financial resources to address opioid-related issues in Michigan. Originating from a $26 billion settlement, nearly $800 million will be allocated over 18 years, with half directed to local governments. Priority funding areas include naloxone distribution, treatment for pregnant women, and support for incarcerated individuals. Additional settlements are expected to enhance resources, emphasizing the importance of community support and addressing the needs of underserved populations impacted by the opioid crisis.

The Cass County Opioid Settlement Funds aim to support organizations addressing opioid use through prevention, treatment, and community support initiatives. The funding prioritizes services for individuals and families affected by opioid use, focusing on racial equity and youth prevention. Grants are available for both emergency and non-emergency interventions, ensuring a fair and transparent process for fund allocation. This initiative seeks to make a significant impact on the community by addressing unmet needs and leveraging collaboration with local service providers.