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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$8.25B

Total funding

$6K

Median grant

33,000+ grants
$8.25B total
$6K median

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32,595 Results based on applied filters

Adams County Opioid Settlement Fund

Adams County
State/Local Government
Adams County, Illinois
Unspecified amount
The Adams County Opioid Settlement Fund aims to address substance use disorders by administering settlement funds to support impactful community projects in Adams County, Illinois. The committee prioritizes core abatement strategies, including naloxone distribution, medication-assisted treatment, and prevention programs. Non-profit and for-profit entities serving the county are eligible to apply, with a focus on projects benefiting local residents. Sustainability and compliance with legal requirements are essential to ensure long-term impact.
Addiction & Substance Use Disorders Drug Use Disorder

Georgia Opioid Crisis Abatement Trust

Georgia Opioid Crisis Abatement Trust
State/Local Government
Georgia (US state)
Unspecified amount
The Georgia Opioid Crisis Abatement Trust aims to eradicate and prevent the opioid crisis in Georgia through collaborative efforts. Established to manage funds from national settlements with opioid manufacturers, the Trust supports addiction prevention, treatment, and recovery services. This initiative aligns with Georgia's strategies for addressing the opioid crisis, inviting eligible organizations to participate in vital programs that promote healing and safeguard future generations.
Addiction & Substance Use Disorders Drug Use Disorder

Bower Foundation Grant

Bower Foundation
Private
Mississippi
Unspecified amount
The Bower Foundation Grant supports innovative strategies to enhance the health of Mississippians through various initiatives. Organizations seeking funding must submit a Grant Concept Summary for consideration. The foundation focuses on improving healthcare access, promoting healthy lifestyles among children, developing innovative health policies, and addressing End Stage Renal Disease. Eligible applicants include tax-exempt organizations and those committed to enhancing health in Mississippi.
Health Policy & Advocacy Health Care Access & Delivery Kidney Diseases +2 more

Veterans & Nature Grant

National Environmental Education Foundation
Private
United States
Up to US $10,000

2026 Veterans and Nature Grant

Supporting the health, well-being, and community connection of America's veterans

The National Environmental Education Foundation (NEEF) is pleased to announce grant funding supported by the American Medical Association (AMA) to expand access to nature-based experiences that support the health, well-being, and community connection of America's veterans. AMA has partnered with NEEF to bring an evidence-based health perspective to this effort, underscoring the growing body of research linking time in nature to improved physical and mental health outcomes.

Background

A Pew Research Center survey found that roughly one in four veterans say the transition back to civilian life was at least somewhat difficult. This is especially true for those who return home with stress or trauma. The National Alliance on Mental Illness estimates 11-20% of veterans are believed to experience post-traumatic stress disorder (PTSD) each year.

Nature offers profound restorative benefits for veterans navigating the challenges of post-service life. Time spent outdoors — whether hiking, fishing, camping, or simply sitting among trees — has been shown by numerous studies to reduce symptoms of PTSD, anxiety, and depression, conditions that affect veterans at disproportionately high rates.

Quieting hypervigilance, allowing space for reflection, fostering camaraderie, and reducing isolation are all mental and physical benefits that be found through outdoor recreation. Using America’s public lands to do so provides a powerful and accessible path forward.

Overview

Through the 2026 Veterans and Nature grant, NEEF aims to expand access to nature-based experiences that support veteran health, well-being, and community connection by

  • Providing opportunities for outdoor activities on public land that improve the physical and mental health of veterans
  • Increasing veterans’ understanding of the physical and mental health benefits of time in nature

The grant will provide up to $10,000 per grantee for projects on federal, state, local, or nonprofit public lands that address physical and mental health in veteran communities.

Examples of project types include outdoor activities, such as hiking, biking, climbing, or fishing; wellness activities, such as forest bathing or meditation; environmental education, such as community science; adaptive programming; and conservation volunteering. Projects are not limited to those listed here.

Mental Health & Psychiatric Diseases Environmental Education Military & Veterans Services +5 more

JCF: Israel Restricted Grants

Jewish Community Foundation Of Greater MetroWest NJ
Private
Israel
Up to US $11,500
The Jewish Community Foundation of Greater MetroWest NJ offers Israel Restricted Grants aimed at supporting specific community needs. These one-year grants focus on initiatives such as aiding Israeli individuals with developmental disabilities, promoting cultural engagement in Ofakim and Merchavim, providing resettlement assistance for Olim, and offering scholarships for Ethiopian Jews in Israel. With a preference for partnership communities, this initiative honors legacy donors through Restricted Endowment Funds.
Women & Girl Services Jewish Culture Intellectual / Developmental Disabilities +3 more

Kaiser Permanente’s Social Health Impact Fund

Baltimore Community Foundation
Private
Anne Arundel County, Maryland, Baltimore City, Maryland +5 more
Up to US $6,500

Baltimore Community Foundation

Mission: Inspire donors to achieve their charitable goals from generation to generation and to improve the quality of life in the Baltimore region through grantmaking, enlightened civic leadership, and strategic investments.

Kaiser Permanente’s Social Health Impact Fund

Unmet social needs such as lack of food, housing, or transportation are barriers to health and well-being. Addressing these needs is an integral part of quality care. As an integrated health system committed to total health, Kaiser Permanente not only provides excellent medical care and support for mental health and wellness, we are also addressing the social health needs of our members and communities. To help address unmet social needs, Kaiser Permanente, in partnership with Unite Us, has deployed the Mid-Atlantic Community Network – a social service resource locator that integrates clinical and social care and is supported by data integration and partnership with community.

Equitable & Affordable Housing Health Disparities & Social Determinants of Health Food Access & Hunger +1 more

NBA Foundation Grants

National Basketball Association Foundation
Private
Canada, United States
More than US $25,000
The NBA Foundation Grants aim to empower Black youth by providing economic opportunities through skills training, mentorship, and career advancement programs. Established by all 30 NBA teams, the foundation focuses on organizations aligned with its mission, specifically those serving Black youth in NBA markets. Applications for 2024 grants are now open, with a review process taking 12-14 weeks. This initiative is crucial for promoting sustainable economic and racial justice in communities.
Career / College Preparation Black American Services Youth Services +2 more

Bianca Michelle Devins Memorial Scholarship

The Community Foundation of Herkimer & Oneida Counties
Private
Oneida County, New York
Unspecified amount
The Bianca Michelle Devins Memorial Scholarship, established by the Devins and Williams families in memory of Bianca Devins, supports students pursuing a degree in psychology. This scholarship aims to empower individuals who aspire to assist adolescents facing mental health challenges. Open to graduates from Utica high schools or the surrounding Central New York area, applicants must maintain good academic standing and demonstrate a commitment to helping children with mental health issues.
Education - Higher Education Psychology Mental Health & Psychiatric Diseases +1 more

Field-of-Interest Grant Program - Economic Development

Community Foundation of Mendocino County Inc.
Private
Mendocino County, California
US $1,000 - US $6,500
The Field-of-Interest Grant Program - Economic Development supports local nonprofits in Mendocino County with grants ranging from $1,000 to $5,500. This program prioritizes initiatives that enhance economic sustainability through technical assistance, financial literacy, and innovative projects. Established in 2016, it aims to foster a healthy and equitable local economy, encouraging collaborative efforts to secure sustainable funding for various community sectors.
Economic Services & Development Financial Literacy Entrepreneurship +1 more

Klamath Community Foundation Grants

Klamath Community Foundation
Private
Siskiyou County, California
Unspecified amount
The Klamath Community Foundation Grants aim to enhance the quality of life for the Klamath Basin community by awarding grants to local non-profit organizations. These grants support various areas including health services, education, community development, and the arts. By pooling resources from donors, the foundation minimizes administrative costs and maximizes funding for impactful projects. This initiative encourages community involvement and aims to address changing needs while preserving the unique character of the Klamath region.
Health & Medicine Human & Social Services Community Development & Revitalization +8 more

Greater Oxford Community Foundation Grants

Greater Oxford Community Foundation
Private
Butler County, Ohio, Clermont County, Ohio +2 more
Unspecified amount
The Greater Oxford Community Foundation Grants focus on enhancing the quality of life in the Greater Oxford area by awarding grants for diverse programs such as education, arts, and social services. They support tax-exempt public charities and prioritize proposals that promote community development. The Foundation emphasizes diversity, equality, and non-discrimination, ensuring that funding is accessible to a wide array of community projects while adhering to specific eligibility criteria.
Education Environmental Conservation Human & Social Services +5 more

Student Research Award Supplement

Regents Of The University Of California, Office Of The President
Private
California
Up to US $20,000

Tobacco-Related Disease Research Program

A portion of California's tobacco product excise taxes are used to fund research grants. These grants are administered by TRDRP.

As one of three state agencies that work together towards a tobacco-free California, we aim to eliminate commercial tobacco use and tobacco-related diseases and to improve the health and well-being of all Californians. TRDRP works with the California Department of Public Health and Department of Education under the guidance of the Tobacco Education and Research Oversight Committee to ensure collaboration across all sectors of California's tobacco control community.

TRDRP is administered by the Research Grants Program Office (RGPO) at the University of California, Office of the President.

Student Research Award Supplement

Purpose

Student Research Award Supplement (SRAS) are intended to foster undergraduate and master’s student research and allow active research training and mentoring by providing supplemental funding to existing TRDRP awards, in order to bring new workforce into the stated TRDRP research priority areas.  

Summary:

  • Maximum supplement amount per year: $20,000 (direct costs).
  • Duration: 1 or 2 years
  • Supplement funds are provided in addition to the parent grant award cap.
Cardiovascular Diseases & Systems Smoking Lung Cancer +1 more

Urban and Community Forestry Grant Program

State of Rhode Island Department of Environmental Management - Natural Resources Bureau
State/Local Government
Rhode Island
US $2,000 - US $10,000
The Urban and Community Forestry Grant Program, previously known as the RI America the Beautiful Grant Program, supports projects enhancing urban and community forest management. This initiative aims to promote sustainable practices, protect trees from various threats, and improve public awareness of the importance of tree cover. Eligible applicants include local and state governments, educational institutions, and certain non-profits. Projects should align with the goals outlined in the Rhode Island Forest Action Plan to qualify for funding.
Forestry Greening & Beautification

Proposition 1 - River Parkways and Urban Streams for LLAR (CA)

California San Gabriel and Lower Los Angeles Rivers and Mountains Conservancy
State/Local Government
Los Angeles County, California
US $300,000 - US $2,000,000
The Proposition 1 - River Parkways and Urban Streams for LLAR (CA) grant focuses on enhancing ecosystems and watershed restoration projects within the Lower LA River corridor. With funding between $300,000 and $2,000,000, the program prioritizes projects that protect the Lower LA River, ensure access for diverse communities, and leverage secured matching funds. The initiative aligns with the Lower LA River Revitalization Plan, emphasizing implementation and planning for sustainable development.
Habitat & Ecosystem Restoration Freshwater Conservation Outdoor Equity +2 more

MACI Youth Fund

Albion Community Foundation
Private
Calhoun County, Michigan
Up to US $2,000
The MACI Youth Fund, managed by the Albion Community Foundation, aims to enhance youth education through group-focused enrichment opportunities. Grants up to $2,000 support cultural, educational, recreational, and environmental programs in the greater Albion area. Nonprofit organizations, public charities, and faith institutions serving this community are encouraged to apply, ensuring projects align with the foundation's mission of community improvement and youth development.
After School / Summer Educational Programs Academic Success & Enrichment Youth Development & Leadership +4 more

Action Against Hunger Grants

Womens Foundation of New Jersey
Private
New Jersey
US $2,000 - US $5,000
Action Against Hunger Grants provide essential financial support to small independent programs in New Jersey that assist women, children, and families facing food insecurity. Offered by the Womens Foundation of New Jersey, these grants typically range from $2,000 to $5,000 and are awarded each fall based on recommendations from the Food Insecurity Task Force. Interested parties can apply through the Letter of Inquiry form on the foundation's website.
Youth Services Family Services Women & Girl Services +2 more

Bronx Cultural Visions Fund- Concept Development and Production Grants

Bronx Council on the Arts
Private
Bronx County, New York, Kings County, New York +3 more
Up to US $20,000
The Bronx Cultural Visions Fund Grant supports the live performing arts in the Bronx by funding new project development for individual artists, collectives, and nonprofit organizations in theater, music, and dance. Grants of up to $20,000 are available for project realization, with an emphasis on emerging and mid-career artists. The program requires participation in cohort meetings and aims to foster long-term relationships within the borough's artistic community.
Performing Arts Dance Music +2 more

Rural Residency Training Grant Program

Minnesota Department of Health
State/Local Government
Minnesota
Up to US $225,000
The Rural Primary Care Residency Training Grant Program aims to enhance primary care residency training in rural Minnesota. With funding between $1.5 to $2 million, it supports planning, accreditation, and training. Grants of up to $225,000 per resident per year are available for sustainable projects. To qualify, programs must demonstrate ACGME accreditation and provide evidence of resident training. This initiative is vital for strengthening the rural physician workforce and improving healthcare access in underserved areas.
Aging / Gerontology Children’s Health & Pediatrics Mental Health & Psychiatric Diseases +3 more

THRIVE Grants from the Fund for York County- up to 10,000

York County Community Foundation
Private
York County, Pennsylvania
Up to US $10,000
The THRIVE Grants program, formerly known as Community Grants, offers funding of up to $10,000 to support initiatives that promote economic mobility for low-income individuals in York County. Managed by the York County Community Foundation, these grants prioritize career development, child and youth development, health, housing, and transportation. Eligible applicants include nonprofit organizations and government agencies dedicated to transforming lives and communities through impactful programs.
Workforce Preparation & Job Readiness Poverty Alleviation & Services Child Welfare Services +2 more

Columbus Motion Picture Incentive (CMPI) Grant

Greater Columbus Arts Council
Private
Delaware County, Ohio, Fairfield County, Ohio +5 more
Up to US $30,000

Greater Columbus Arts Council

Our mission: To champion and elevate the arts and cultural expression of Greater Columbus.

The Greater Columbus Arts Council supports artists and arts organizations through a spectrum of grant programs, workshops, networking events and services. GCAC also shares a host of resources such as calls for artists, job opportunities, nonprofit board openings and listings of spaces for rent.

GCAC provides marketing services that support artists and organizations through the ColumbusMakesArt.com event calendar, Artist Directory, and Public Art Database. We also produce the annual Big Arts Night recognizing business and individual contributions to the community and the Columbus Arts Festival, the city’s welcome to summer event that takes place each June.

Columbus Motion Picture Incentive

Purpose

The Columbus Motion Picture Incentive (CMPI) fuels the growth of the film industry in Central Ohio by encouraging productions to hire local talent, utilize regional resources, and film within the area—all while supporting local filmmakers and strengthening the creative economy.

The Columbus Motion Picture Incentive (CMPI) is open to any production company, whether local or international, that spends a minimum of $150,000 in Franklin and surrounding counties.

Film Documentaries Media Arts +1 more

Benton Telecommunications Foundation Grant - Requests under $2,000

Benton Telecommunications Foundation
Private
Benton County, Minnesota
Up to US $2,000
The Benton Telecommunications Foundation offers small grants under $2,000 to support initiatives in healthy living, basic human needs, educational development, and community improvement. The foundation emphasizes values, ethics, and character formation, aiming to make a positive impact on communities, particularly in Benton County, Minnesota. Applications are reviewed monthly, focusing on the potential benefits of proposed activities and the financial need of individuals affected by disasters.
Wellness & Healthy Living Basic Human Needs Education +6 more

Best Buddies Grant

Texas Education Agency
State/Local Government
Texas
Up to US $1,250,000

Texas Education Agency

The Texas Education Agency is the state agency that oversees primary and secondary public education. It is headed by the commissioner of education. The Texas Education Agency improves outcomes for all public school students in the state by providing leadership, guidance, and support to school systems.

The Division of Governance Interventions supports TEA’s mission and vision by providing exceptional leadership, guidance, and support to school system leadership teams and governing boards. The division collaborates with external field support agents appointed by the TEA Commissioner of Education to build sustainable systems aligned to core TEA initiatives, so that the school system thrives after the release of agency intervention. 

Best Buddies Grant Program

Program Description

The purpose of the Best Buddies grant program is to provide support in creating opportunities for one-to-one friendships, integrated employment, and leadership development for Texas middle school and high school students with intellectual and developmental disabilities (IDD).

Academic Success & Enrichment Education - Middle School Education - High School +2 more

Preventing Suicide and Interpersonal Violence Among Youth and Young Adults

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The CDC's National Center for Injury Prevention and Control invites research proposals aimed at reducing suicide and interpersonal violence among youth aged 10 to 24. This funding opportunity encourages the evaluation of pre-existing primary prevention strategies that have not yet been rigorously assessed. Proposed approaches may include community programs and policies designed to enhance social connectedness, mitigate harmful online behaviors, and address technology-facilitated interpersonal violence.
Youth Services Suicide Prevention

Georgia Making the Shade Program Grant

Georgia Forestry Commission
State/Local Government
Georgia (US state)
Up to US $10,000
The Georgia Making the Shade Program Grant aims to enhance elementary school campuses by funding the planting of trees in playground areas. With grants up to $10,000, eligible applicants include schools, PTAs, and community groups. The program promotes healthier environments by reducing UV exposure, improving air quality, and creating shaded spaces for children. It encourages community involvement through local partnerships and aims to foster educational activities around tree planting and maintenance.
Greening & Beautification Forestry

Dementia CAReS Grants for American Indian and Alaska Native Communities

US Dept. of Health & Human Services: Indian Health Service
Federal Government
United States
US $750,000
The Dementia CAReS Grants aim to enhance the lives of American Indian and Alaska Native communities facing dementia challenges. This initiative provides mini-grants, training, and support to foster multi-disciplinary networks and promote local health practices. By documenting success stories and implementing evaluation plans, the program seeks to drive innovation and improve care outcomes across Tribal and Urban Indian settings. Communities are encouraged to engage collaboratively for meaningful impact.
Indigenous Health Systems Native American Services Indigenous Services +1 more

AWWA Scholarship Program - Veolia Water Technologies & Solutions Vernon D. Lucy III Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $5,000
The AWWA Scholarship Program, specifically the Veolia Water Technologies & Solutions Vernon D. Lucy III Scholarship, offers a $5000 award to undergraduate students pursuing careers in the water sector. Established by the American Water Works Association, this scholarship honors the mentorship of Vernon D. Lucy III and aims to support the next generation of water industry professionals. Eligible candidates must demonstrate interest in water-related fields, underscoring AWWA's commitment to fostering future leaders.
Water Resource Management Academic Scholarship Programs

AWWA Scholarships Program - Mueller Water Products Continuing Education Scholarship

American Water Works Association (AWWA)
Association/Society
North America
US $5,000
The AWWA Scholarships Program, led by the American Water Works Association, aims to support the future of the water industry by investing in students. The Mueller Water Products Continuing Education Scholarship awards $5,000 to an undergraduate student employed by a water utility, emphasizing the importance of practical experience in education. This scholarship not only aids financial needs but also encourages students to pursue careers in water supply, fostering growth in this vital sector.
Water Resource Management Academic Scholarship Programs

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.