Best Large Grants for Nonprofit Organizations

The Promoting First Relationships-Agency Training Project aims to engage community-based agencies in training models that enhance parent-child relationships. Funded by the Seattle King County Department of Public Health, this initiative supports applications for varying amounts between $2,000 and $20,000. The project is part of the Best Starts for Kids initiative, which focuses on fostering healthy development for children and families in King County, ensuring they thrive in a supportive environment.

Department of Energy and Environment

The Department of Energy and Environment (DOEE) is the leading authority on energy and environmental issues affecting the District of Columbia. Using a combination of regulations, outreach, education, and incentives, our agency administers programs and services to fulfill our mission. We work collaboratively with other government agencies, residents, businesses, and institutions to promote environmentally responsible behavior that will lead to a more sustainable urban environment.

Private Fleet Diesel Electrification and Low-NOx

The Department of Energy and Environment (DOEE) solicits grant applications from eligible entities. The goal of this Request for Applications (RFA) is to improve public health by reducing diesel emissions in the District by replacing class 4+ medium- or heavy-duty diesel-powered vehicles with zero-emission vehicle equivalents. The number and amount of grants will vary depending on DOEE’s evaluation of the applications.

Purpose of the Grant

The purpose of this grant is to select and replace diesel vehicles with zero-emission vehicle equivalents, when these replacements will have a significant community benefit. DOEE will rebate a portion of the cost of vehicle replacements in fleets owned by non governmental organizations, faith-based organizations, universities, or private enterprises.

Maryland Center for School Safety

An independent unit of state government established to promote, support, and enhance school communities that are safe for learning and teaching. 

FY2027 Safe Schools Fund Grant (SSFG)​

About the SSFG Grant

The Safe Schools Fund grant (SSFG) is a non-competitive, State-funded grant program designed for local school systems in Maryland. The primary purpose of the Safe Schools Fund grant is to provide funding for school safety and security-related matters as described under Md. Code Ann., Educ. Art. §7-1512. The grant funds will be applied toward the cost of school safety-related projects and services.

The MI Natural Resources Trust Fund Grants support projects aimed at protecting natural resources and enhancing outdoor recreation in Michigan. A minimum of 25% of the fund is allocated for public land acquisition and development of recreational facilities. Eligible projects include land acquisitions, fishing and hunting facilities, and various recreational developments. Grants range from $15,000 to $400,000 for development projects, with no limits for land acquisition. Applications are assessed based on established criteria.

About John’s Island Foundation (JIF)Mission: The John’s Island Foundation (JIF) provides grant funding for capital needs to nonprofit agencies that serve residents in Indian River County. Agencies eligible for funding are those that serve people in need and whose programs are directed toward meeting needs or assisting with issues related to food, shelter, disabilities, health, aging, abuse, or education.About the Leadership GrantsLeadership Grants are awarded for larger, often multi-year capital projects that are expected to drive significant impact and have lasting benefits in Indian River County. If a request is part of a large-scale project, please email to discuss the leadership grant process. 

CDBG Public Services

Funding Opportunity Details

Approximately $1,210,432 in federal Community Development Block Grant (CDBG) funds are available to cities and counties through the state of Iowa’s Public Services Program. All incorporated cities and all counties in the State, except those designated as HUD entitlement areas, are eligible to apply for and receive funds under this program. The Applicant will establish a subrecipient agreement with the participating nonprofit entity (“Subrecipient Partner”) for implementation of the program. Additionally, all Applicants & Subrecipient Partners must work with a Grant Administrator that complies with IEDA’s Certified Grant Administrator Policy (typically council of government or IEDA-approved consultant) to submit the application and conduct grant administration / project delivery.

The purpose of the Public Service Program is to support essential service providers, Homelessness Service Providers and Food Pantries, that address the most urgent and persistent needs of low- and moderate-income households in Iowa. By focusing resources on these high impact service areas, the program aims to support local safety nets, access to nutritious food, and individuals and families experiencing housing instability to improve community resilience. These investments complement broader CDBG goals by ensuring vulnerable Iowans receive the immediate services necessary to achieve long-term housing, health, and economic stability. 

The Capitol Hill Community Foundation offers Fall and Spring Grants to support local programs in education, youth, arts, social services, and community spaces. Each grant can provide up to $3,000 to nonprofits, schools, and neighborhood groups that enhance the lives of Capitol Hill residents. Since 1989, the Foundation has contributed over $6.6 million to various projects, fostering a stronger and more caring community.

The Manistee Community Foundation Grant Program aims to foster community growth and development in Manistee County. Established in 1987, the Foundation invites proposals that address local needs and inspire innovative solutions. By engaging donors and partners, the program seeks to create lasting impacts through strategic investments. Applicants are encouraged to submit a Grant Inquiry Form to determine eligibility for funding. The Foundation values community input and looks forward to supporting initiatives that enhance the quality of life for all residents.

The 2025-2026 Autism Supports Grant, administered by the Texas Education Agency, aims to enhance the capacity of Texas public schools to support students with autism. By providing subgrants to local educational agencies, charter schools, and nonprofit organizations, this initiative focuses on implementing evidence-based practices that address the unique academic and behavioral needs of students with disabilities, ensuring high expectations are met.

The Fred J. Brunner Foundation Grant supports organizations that aid vulnerable populations, particularly the young and elderly, through education, shelter, and hunger initiatives. Established in 1956 by Fred J., the foundation distributes grants annually in the fall, focusing primarily on recipients in the greater Chicago area, although exceptions are made. The foundation operates without regard to race, creed, or ethnicity, allowing all recipients to reapply each year.

The Forever Idaho Regional Grant Program, managed by the Idaho Community Foundation, connects donors with community needs to foster impactful solutions. Established in 1988, this program supports various initiatives across Idaho, including arts, education, health, and housing stability. Grants are available for diverse operating expenses, allowing nonprofits to address pressing local issues effectively. The program emphasizes community-driven philanthropy and adapts to the evolving requirements of Idaho's communities.

The Forever Idaho Regional Grant Program, managed by the Idaho Community Foundation, supports nonprofit organizations in Eastern Idaho. With grants ranging from $3,000 to $8,000, it prioritizes projects in areas like arts, community benefit, education, environment, health, and housing stability. This initiative fosters collaboration and addresses evolving community needs, ensuring that charitable efforts effectively enhance the quality of life for Idahoans. Organizations in specific counties are encouraged to apply for these impactful grants.

The Season/Series Arts Support Grant is designed to assist arts organizations in Minnesota's Beltrami, Hubbard, Clearwater, Lake of the Woods, and Mahnomen counties. It allows for a single application to fund multiple arts activities, aiming to save time and resources for nonprofits. Eligible proposals include public arts projects, educational performances, and community engagement initiatives that demonstrate a commitment to expanding arts programming and removing barriers to access.

The Indiana County Endowment Grant, established by the Pittsburgh Foundation, aims to address community needs by funding qualified nonprofit organizations in Indiana County, PA. The grant supports initiatives that promote cultural, social, educational, and economic development, encouraging creative engagement among residents. It provides seed money for new projects, event support, and property improvements, enhancing the overall quality of life in the region. However, it does not cover normal operating expenses or commercial enterprises.

Thunderbirds Charities, established in 1986, aims to enhance the quality of life in Arizona communities by supporting at-risk youth, education, and families in need. They provide grants generated from the Waste Management Phoenix Open. Eligible applicants must be 501(c)(3) nonprofits based in the Greater Phoenix area, while ineligible organizations include those with less than three years of 501(c)(3) status and those that discriminate or engage in political advocacy.

The Special Projects Grants, offered by the North Dakota Council on the Arts, open for applications on July 1, 2025. This reimbursement grant program supports art events across various disciplines, providing up to $1,500 for North Dakota groups and individual artists. Applications must be submitted six weeks prior to the activity's start date, with the latest project end date set for June 30, 2026. Don't miss this opportunity to enhance the local arts scene.

The Albrecht Family Foundation, established in 2007, supports organizations in the Greater St. Louis area that promote self-sufficiency through education and training. With a strong family commitment to the region, the foundation values creativity and entrepreneurial solutions. It has previously contributed to local institutions such as St. Louis Children’s Hospital and the University of Missouri, reflecting its dedication to enhancing community welfare and fostering new opportunities.

Massachusetts Department of Environmental Protection (MASSDEP)

MassDEP's mission is to protect and enhance the Commonwealth's natural resources - air, water, and land - to provide for the health, safety, and welfare of all people, and to ensure a clean and safe environment for future generations. In carrying out this mission MassDEP commits to address and advance environmental justice and equity for all people of the Commonwealth, provide meaningful, inclusive opportunities for people to participate in agency decisions that affect their lives; and ensure a diverse workforce that reflects the communities we serve.​

MassDEP Commercial Refrigeration Grant

This program provides financial incentives for retail food businesses, food banks, and nonprofit organizations to install more climate-friendly commercial refrigeration equipment.

Through its Commercial Refrigeration Grant Program, MassDEP is providing financial incentives for voluntary adoption of more climate-friendly, low global warming potential (GWP) refrigerants in commercial refrigeration equipment across the state.

MassDEP will pay your grant funds on a reimbursement basis after you submit invoices and required documentation.

Eligible Projects

Program funding to support projects for ultra-low-GWP systems is available for new or existing retail food locations, food banks, and nonprofit institutions in Massachusetts that plan to install refrigeration systems that contain ultra-low-GWP (<10) refrigerants. Eligible costs for ultra-low-GWP systems include the cost of the refrigeration equipment and its installation.

Eligible Project Types: Type I – New Facilities; Type II – Existing Facilities

Type II – Existing Facilities

Installation of ultra-low-GWP (<10) refrigerant systems

• Full system conversion
• Partial system conversion

The Rutherford County Endowment Grant, offered by The Community Foundation of Western North Carolina, provides funding between $2,500 and $10,000 to nonprofit organizations and public agencies that serve Rutherford County. This grant aims to foster philanthropy and enhance charitable activities, with priority given to projects that demonstrate significant community benefits in areas such as education, health, and the environment. Eligible organizations must have a history of substantial work in the area.

The Vera and Joseph Dresner Foundation supports organizations in Southeast Michigan and Metropolitan Denver focused on improving lives through health, youth, and animal welfare initiatives. They offer grants for project development, capital expenses, and unique circumstances. The foundation prioritizes innovative solutions that address underserved community needs, ensuring sustainable impact and enhanced access to essential services. Applicants must be 501(c)(3) organizations and demonstrate non-discriminatory practices in their operations.

Kansas Department of Transportation 

KDOT delivers transportation that keeps Kansans moving forward.

We maintain thousands of miles of roadways to keep people and goods moving smoothly across the state. Our dedicated team plans, builds, and maintains highways, bridges, and other infrastructure with a focus on safety and innovation.

By working closely with local communities and stakeholders, KDOT aims to enhance the quality of life for all Kansans, support economic growth, and improve travel experiences. 

Kansas Safe Route to School (SRTS) Grants

Grants and funding opportunities are available to support Safe Routes to School planning, programs, and infrastructure improvements. These include the Kansas SRTS Planning Grant, Kansas SRTS Programming Grant, and Transportation Alternatives (TA) Program.

Programming Grants

Programming Grants provide funding over three years to implement education, encouragement, and enforcement (non-infrastructure) strategies identified in a community’s SRTS Plan. A 10% local match is required.

The SRTS Programming Grant is for Kansas communities with an existing SRTS Plan. The Grant is for a three-year period and provides up to $75,000 to support implementation of programming priorities identified in your SRTS Plan. See our completed plans here.

What to Expect if Awarded

Programming Grant recipients should be prepared to work with KDOT SRTS staff to finalize a scope for the program before it begins. KDOT staff will not implement programming. Grant funds can be used to supplement existing staff or hire consultant services through an RFP. The local project lead will meet with KDOT staff throughout the grant period to discuss program progress and outcomes.

The Greater Columbus Arts Council (GCAC) offers the 'Funds for Artists' program to support individual artists in various disciplines, including dance, music, and visual arts. This grant assists with costs for materials, professional development, and marketing, providing up to $750. Eligible applicants must be working artists, residents of Franklin County, and over 18 years old. Notably, those enrolled in undergraduate programs or residing outside Franklin County are not eligible. The initiative aims to foster new artistic creations and enhance skills.

The TCA Texas Arts Create 2 Grant, offered by the Texas Commission on the Arts, aims to support Established Minority Arts Organizations with budgets exceeding $50,000. This grant provides multi-year operational support, allowing organizations to apply for funding covering one year, with potential extension based on available funds. Eligible organizations must be tax-exempt nonprofits and comply with various federal regulations. The program seeks to enhance the creative economy in Texas, fostering a diverse and innovative arts community.

Kansas Department of Transportation 

KDOT delivers transportation that keeps Kansans moving forward.

We maintain thousands of miles of roadways to keep people and goods moving smoothly across the state. Our dedicated team plans, builds, and maintains highways, bridges, and other infrastructure with a focus on safety and innovation.

By working closely with local communities and stakeholders, KDOT aims to enhance the quality of life for all Kansans, support economic growth, and improve travel experiences. 

Kansas Safe Route to School (SRTS) Grants

Grants and funding opportunities are available to support Safe Routes to School planning, programs, and infrastructure improvements. These include the Kansas SRTS Planning Grant, Kansas SRTS Programming Grant, and Transportation Alternatives (TA) Program.

Planning Grants

Planning Grants provide technical assistance to help communities develop SRTS Plans. No local match is required, and KDOT's consultant team works directly with communities to create a plan that guides future SRTS improvements.

What is in a SRTS Plan?

SRTS Plans include an analysis of existing conditions, summary of public outreach, and identification of potential infrastructure and non-infrastructure solutions to help more students walk, bike, and roll to school. See our completed plans here.

How many schools can be included in one plan?

SRTS plans can be developed for one (1) school or up to eight (8) schools within a single school district. Elementary, middle, and high schools are all eligible for SRTS plans. For districts with more than eight schools contact KDOT’s SRTS Coordinator for assistance with selecting schools for the application.

If selected, grantee should be prepared to support plan development by meeting regularly with the project team (KDOT and their consultant), providing information, surveying parents and students (with online tools provided by the consultant team), helping to arrange and publicize public workshops, and participating in identifying local issues and solutions. Additionally, the grantee should be able to demonstrate a commitment to implementing the plan once it is complete.

How to Use Your Completed SRTS Plan

A completed SRTS Plan can be used as a communication and visualization tool for grant applications and to support SRTS programs and activities in your community. It can also be used as a catalyst for broader community conversations about walking, biking, and rolling.

The Carthage Community Foundation Grant supports 501(c)(3) organizations and IRS-approved entities serving the Carthage area. This initiative aims to enhance community life through innovative projects in key areas such as health, education, arts, and nutrition. Applicants must provide a detailed budget and can only apply once for funding. Grants should be utilized within one year, ensuring impactful use of resources for community development.

The Greater Columbus Arts Council's Artist Projects grant supports original, artist-led projects in all disciplines within Columbus. It aims to foster artistic creation and ensures that artists have the freedom to define their project's goals. Eligible artists must be working in various art forms, including dance, film, and visual arts, and demonstrate community value. Awards can reach up to $10,000 for artists and $25,000 for filmmakers, promoting a vibrant arts scene in the city.

The Intervention Research to Improve Native American Health (IRINAH), led by the National Institute on Drug Abuse, focuses on enhancing health outcomes in Native populations. It supports research to identify causes of health issues, develop and test effective interventions, and implement strategies that promote sustainability. Emphasizing community strengths, the initiative aims to rigorously evaluate solutions to reduce health disparities, ensuring interventions can be adapted and shared across diverse communities.