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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,565 Results based on applied filters

ISF Social Justice Short Film Grant

Islamic Scholarship Fund
Association/Society
United States
Up to US $10,000
The ISF Social Justice Short Film Grant supports emerging Muslim filmmakers in creating impactful short narrative or documentary films that address social justice issues. Launched in 2014 by the Islamic Scholarship Fund, this program aims to raise awareness and provoke dialogue about inequality and oppression. With a total of $625,000 awarded, the grant offers funding along with mentorship and networking opportunities to enhance storytelling and community impact.
Social Justice / Human Rights Film Documentaries +1 more

Melinda Henning Scholarship

Community Foundation Of Mahoning Valley
Private
United States
Unspecified amount

About Us

Leadership. Collaboration. Impact.

The Community Foundation of the Mahoning Valley helps philanthropists support the causes closest to their heart while connecting local residents to the resources they need for a better quality of life.

Our Mission

To serve as a leader and advocate for strategic philanthropy, partnering with donors to anchor a permanent and growing endowment and making investments in the Mahoning Valley that improve the quality of life for all residents.

Scholarship Opportunities

Your Community, Your Support System

Our community members support hundreds of local students every year through various scholarships facilitated by the Community Foundation of the Mahoning Valley.

Established in memory of Melinda “Mindy” Henning.

Education - Higher Education Environmental Education Recreation +2 more

AMA Foundation Section Involvement Grant Program

American Medical Association Foundation
Private
United States
Up to US $1,500
The AMA Foundation Section Involvement Grant Program supports local campus section leaders at medical schools in enhancing student recruitment and engagement. Grants can provide up to $1,500 per year, with specific allocations for recruitment and community service activities. Examples of supported activities include organization fairs, public health lectures, and community workshops. This initiative aims to foster student involvement and empower local AMA sections to address important health topics within their communities.
Medical Education & Professional Training Epidemiology & Public Health Community Health Education +2 more

Stoughton Area Community Foundation Grants

Stoughton Area Community Foundation
State/Local Government
Dane County, Wisconsin
US $300 - US $5,000
The Stoughton Area Community Foundation Grants support local organizations and individuals, enhancing community life through charitable funding. Grants range from $300 to $5,000 and focus on areas such as arts, education, health, and community development. Established in 1998, the foundation aims to connect donors with causes that matter, fostering collaboration and volunteerism to address local needs. Applications are reviewed annually, with deadlines set for September 15th.
Human & Social Services Art & Culture Community Development & Revitalization +7 more

CCWC Cultural Coalition Grant

Oregon Cultural Trust
Private
Washington County, Oregon
US $1,000 - US $3,000
The CCWC Cultural Coalition Grant supports nonprofit arts, heritage, and humanities organizations in Washington County. Through the Community Cultural Participation Grant Program, it aims to promote public awareness, support diverse cultural activities, and increase access to arts education. Grants range from $1,000 to $3,000, encouraging projects that enhance community engagement and cultural tourism. This initiative fosters cultural diversity and partnerships, enriching the region's cultural landscape.
Community Culture & Heritage Arts / Culture Access & Participation Art & Culture +4 more

Scioto Foundation Regular Grant

The Scioto Foundation
Private
Scioto County, Ohio
Unspecified amount

Scioto Foundation

The Scioto Foundation is a community foundation serving the people of the Scioto County area. Since 1975, SF has awarded approximately $30 million in grants and distributions to local non-profit organizations, schools, and local governments. 

Regular Grant 

Typically, the Foundation funds projects in the following areas: education, healthcare, community development, economic development, arts and culture, social services, and civic benefit.

  • The Foundation is interested in those organizations that can demonstrate they have planned their projects in light of overall community needs. Similar projects by other organizations should not duplicate the proposed services.
  • The Foundation will look favorably at those projects that promise to affect a broad segment of the population of the Scioto County area or that tend to help a segment of the citizenry not being adequately served by other resources in the community.
  • The Scioto Foundation is especially interested in supplying the “seed money” for new and dynamic projects. Grants will be made to existing groups moving in new directions or to new organizations.
  • As a rule, the Scioto Foundation prefers projects that occur in a one-year time frame.

The board will review applications for the regular grant rounds quarterly.

Educational Access & Equity Economic Services & Development Community Development & Revitalization +4 more

Community Development Block Grant (CDBG) - Neighborhood Revitalization (CDBG-NR)

North Carolina Department of Commerce
State/Local Government
Alamance County, North Carolina, Alexander County, North Carolina +94 more
Up to US $5,000,000

GRANT PERIOD AN

North Carolina Department of Commerce

Our mission is to improve the economic well-being and quality of life for all North Carolinians.

To do that, the North Carolina Department of Commerce works closely with local, regional, national and international organizations to propel economic, community and workforce development for the state.

Community Development Block Grant Neighborhood Revitalization Program (CDBG-NR)

The Community Development Block Grant Neighborhood Revitalization Program (CDBG-NR) will offer a non-entitlement municipality or county the opportunity to tailor a project to meet the housing and community development needs specific and most critical to their locality. The CDBG Neighborhood Revitalization Program incorporates several previous Rural Economic Development Division (REDD) Community Development Block Grant (CDBG) programs and activities such as Scattered Site Housing and Supportive Housing.

The CDBG Neighborhood Revitalization Program will support the three livability principles that help guide sustainability and resiliency throughout areas that receive funding. Regardless of the program activity or activities local governments pursue, CDBG Neighborhood Revitalization Program projects must incorporate at least one of the following three livability principles as an area of focus:

NC Neighborhood Revitalization 3 Livability Principles

  • Promote equitable, affordable housing. Expand location and energy-efficient housing choices for people of all ages, incomes, races, and ethnicities to increase mobility and lower the combined cost of housing and transportation.
  • Support existing communities. Target federal funding toward existing communities - through strategies like transit-oriented, mixed-use development, and land recycling - to increase community revitalization and the efficiency of public works investments and safeguard rural landscapes.
  • Value communities and neighborhoods. Enhance the unique characteristics of all communities by investing in healthy, safe, and walkable neighborhoods - rural, urban, or suburban.
Community Development & Revitalization Equitable & Affordable Housing Economic Services & Development +1 more

Benjamin A. Black Charitable Trust for Children Grant

Benjamin A. Black Charitable Trust for Children
Private
Nebraska
US $1,000 - US $5,000
The Benjamin A. Black Charitable Trust for Children provides essential support to economically deprived children in central Nebraska. Established in 1990, it honors Benjamin A. Black's legacy by funding programs that offer necessities and joy, such as Christmas gifts. Grants are targeted towards public charities that directly benefit children, with a focus on areas outside Omaha and Lincoln. Applications are accepted year-round, with a deadline of March 31 for annual review.
Poverty Alleviation & Services Child Welfare Services Basic Human Needs +4 more

Community Development Block Grant: Disaster Recovery (CDBG-DR) — Oklahoma

Oklahoma Department of Commerce
State/Local Government
Carter County, Oklahoma, McClain County, Oklahoma +2 more
Unspecified amount

Oklahoma Department of Commerce

Here at the Department of Commerce, our job is to bring employment, investment, and economic prosperity to the state of Oklahoma. Through dynamic partnerships and innovative collaborations with companies, universities, not-for-profit organizations, and government leaders, we are building a business environment that supports business growth and shared community prosperity.

Community Development Block Grant Programs

The Community Development Block Grant (CDBG) program enables rural Oklahoma communities to finance a variety of public infrastructure and economic improvements and helps promote job growth as a result of these improvements. CDBG funds are provided by the federal government (U.S. Department of Housing and Urban Development) and managed by the Oklahoma Department of Commerce to help ensure Oklahoma’s most critical needs are addressed.

CDBG Disaster Recovery Program (CDBG-DR)

The Community Development Block Grant Disaster Recovery Program (CDBG-DR 2023/2024) grants are intended to support communities affected by the DR-4706 and DR-4776 disasters. Eligible counties are Carter, McClain, Murray, and Osage County. 

Introduction

On behalf of the Oklahoma Department of Commerce Community Development Division (ODOC/CD), we appreciate the opportunity to partner with eligible communities and applicants as recovery and rebuilding efforts continue following recent federally declared disasters. The CDBG-DR program is intended to support long-term recovery, infrastructure restoration, housing stabilization, and community resiliency in accordance with federal disaster recovery requirements established by HUD.

Disaster Relief / Humanitarian Aid Public Infrastructure Community Development & Revitalization +1 more

R.C. Smith Foundation Grants

R C Smith Foundation Inc
Private
Chenango County, New York
Unspecified amount
The R.C. Smith Foundation Grants support community initiatives in Chenango County, focusing on 501(c)(3) organizations that benefit local residents and programs. Established in 2005, the foundation prioritizes contributions to religious groups, youth programs, and food pantries. With a dedicated board that meets quarterly, the foundation ensures a thoughtful review of grant applications, promoting the welfare of the community through strategic funding efforts.
Catholicism Youth Services Food Delivery & Distribution Services +1 more

CFNI: Neighborhood Grants Program

Community Foundation of Northern Illinois
Private
Boone County, Illinois, Ogle County, Illinois +2 more
Unspecified amount
The CFNI Neighborhood Grants Program encourages community engagement by funding resident-led projects that enhance local quality of life. It supports initiatives such as community gardens, crime prevention, and beautification projects, focusing on partnerships among residents and organizations. Eligible applicants include 501c3 non-profits and neighborhood associations within specific counties in Illinois. The program aims to strengthen neighborhoods by leveraging local assets and fostering civic pride.
Greening & Beautification Crime & Justice Horticulture & Gardening +2 more

Jack and Judy Schiller Dyslexia Fund

Ottawa County Community Foundation Inc
Private
Ottawa County, Ohio
Unspecified amount
The Jack and Judy Schiller Dyslexia Fund supports initiatives that promote dyslexia awareness and facilitates identification and remediation for children with dyslexia. Grants are exclusively awarded to non-profit organizations with 501(c)(3) tax-exempt status, focusing on projects that address dyslexia and reading disabilities in Ottawa County. This funding aims to enhance educational outcomes and provide necessary resources for affected students.
Education Neurological Diseases & Disorders Special Needs Education +2 more

MCCF Yearly Grant Program

Mahaska County Community Foundation
Association/Society
Mahaska County, Iowa
Unspecified amount
The Mahaska County Community Foundation (MCCF) Grant supports local 501(c)(3) nonprofits and governmental bodies in Mahaska County. With an emphasis on arts, education, health, and youth development, the foundation aims to enhance community quality of life through innovative projects. No minimum or maximum grant amounts are specified, encouraging diverse applications. Notably, MCCF does not fund completed projects or ongoing operational support, ensuring that resources are directed toward new initiatives with community impact.
Educational Access & Equity Arts / Culture Access & Participation Recreation +2 more

W. W. Burgiss Charities Grant

W. W. Burgiss Charities, Inc.
Private
Greenville County, South Carolina
Approximately US $12,000
The W. W. Burgiss Charities Grant supports initiatives focused on religion, education, and assistance for the needy in Greenville County, South Carolina. Established by W. W. Burgiss in 1925, the foundation prioritizes capital needs and one-time special projects, aiming to create measurable impacts. Eligible organizations must be 501(c)(3) exempt and demonstrate financial sustainability. With an average grant size of $12,000, the foundation aims to uplift the sick and underprivileged, ensuring local community enhancement through targeted funding.
Religion & Spirituality Education Volunteerism & Philanthropy +4 more

Innovative Research to Improve Native Hawaiian and Pacific Islander (NHPI) Health Outcomes (R34 - Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Minority Health and Health Disparities (NIMHD) is offering funding for innovative research aimed at improving health outcomes for Native Hawaiian and Pacific Islander populations. This grant will support preparatory and pilot activities that focus on understanding health disparities, testing interventions for chronic diseases, and promoting health behavior changes in collaboration with community partners. Projects should address critical health issues such as cancer, diabetes, and maternal health.
Health & Medicine Indigenous Health Systems Native American Services +2 more

Specialty Crop Community Orchard Grant

North Dakota Department of Agriculture
State/Local Government
North Dakota
More than US $40,000

About Us

Welcome to www.ndda.nd.gov, the website of the North Dakota Department of Agriculture.

Agriculture is the dominant sector of our state's economy. Our 26,000 farmers and ranchers lead the nation in the production of more than a dozen important commodities, among them wheat, durum, barley, flax, canola, pulse crops and more.

Agriculture Commissioner Doug Goehring and the Department staff are committed to promoting a healthy economic, environmental and social climate for agriculture and the rural community through leadership, advocacy, education, regulation and other services. We believe that a strong agricultural economy is vital to the long-term well-being of North Dakota, our country and the world.

Specialty Crop Community Orchard Grants

The North Dakota Department of Agriculture (NDDA) has a grant opportunity to support the creation of permanent community orchards in underserved regions to increase community access to and consumer education of specialty crops. The funds for these grants come from the USDA Specialty Crop Block Grant program.

Eligible organizations can ask for $40,000 or more to establish a new community orchard.

Horticulture & Gardening Greening & Beautification Agricultural Crops +3 more

ISF Distribution Grant

Islamic Scholarship Fund
Association/Society
United States
Up to US $5,000
The ISF Distribution Grant, offered by the Islamic Scholarship Fund, aims to support emerging Muslim filmmakers in distributing completed narrative and documentary films. Launched in 2014, the program fosters positive storytelling about the Muslim community. Grant recipients receive funding, mentorship, and networking opportunities to enhance their projects. With over $625,000 awarded to date, this initiative emphasizes the importance of showcasing diverse narratives through festival submissions and digital platforms, ensuring broader audience engagement.
Film Documentaries Islam & Islamic Culture +1 more

Margaret Frans Brady Scholarship for Arts

Juneau Community Foundation
Private
Sitka City and Borough, Alaska, Skagway Municipality, Alaska
Up to US $10,000
The Margaret Frans Brady Scholarship for Arts, established by the Juneau Community Foundation, aims to support arts and education initiatives in Skagway and northern Southeast Alaska. This fund assists students and artists by providing scholarships to enhance their creative skills across various disciplines, including writing, music, and visual arts. Grants of up to $10,000 may be awarded to help participants attend arts-related programs, camps, or educational institutions.
Education Writing & Literature Performing Arts +4 more

Arts Alive! Organizational Grants

The Weld Community Foundation
Private
Weld County, Colorado
Up to US $3,000
The Arts Alive! Organizational Grants, funded by the Weld Community Foundation, support innovative projects that enhance the arts in Weld County. These grants aim to expand artistic access, promote cultural diversity, and foster community engagement through the visual, performing, and literary arts. Ideal proposals should serve underserved populations, offer measurable outcomes, and have a positive impact on local artistic endeavors, ensuring a vibrant cultural landscape in the community.
Visual Arts Conceptual Art / Performance Art Writing & Literature +4 more

MSCRF Validation Program RFA

Maryland Stem Cell Research Fund
State/Local Government
Maryland
Up to US $250,000
The Maryland Stem Cell Research Fund (MSCRF) Validation Program aims to accelerate the transition of innovative stem cell technologies from research labs to the commercial sector. With funding of up to $250,000, the program supports projects that address unmet medical needs, fosters collaborations between academic and private sectors, and emphasizes the development of new medical strategies for human diseases. This initiative is vital for advancing stem cell research and enhancing healthcare outcomes in Maryland.
Cell Biology Genetics & Genomics Entrepreneurship +4 more

NTCA Event Funding

North Tahoe Community Alliance (NTCA)
Private
Placer County, California
Unspecified amount
The North Tahoe Community Alliance (NTCA) is offering event funding for 2025, supporting initiatives that enhance economic health, community vitality, and environmental stewardship. Applications open on December 13, with a deadline of January 10. Events must promote public engagement and sustainability while being open to all. Funding priorities include community enhancement, environmental stewardship, and workforce housing, ensuring that events positively impact the region's economy and community spirit.
Economic Services & Development Community Development & Revitalization Volunteerism & Philanthropy +2 more

Chicago Fund for Safe and Peaceful Communities Grants

The Chicago Community Trust
Private
Cook County, Illinois
US $1,000 - US $10,000
The Chicago Fund for Safe and Peaceful Communities Grants, initiated by the Partnership for Safe and Peaceful Communities in 2016, aims to reduce violence during summer months. It supports community-based organizations that foster safety and cohesion. This Fund provides rapid-response grants to empower local initiatives, addressing immediate needs while complementing broader violence prevention efforts. By targeting neighborhood-based groups, it seeks to deliver timely support to those actively working for a safer Chicago.
Community / Public Safety Violence Prevention Peacebuilding +1 more

Stein Family Charitable Trust Grant

Stein Family Charitable Trust
Private
Tarrant County, Texas
US $10,000 - US $20,000
The Stein Family Charitable Trust Grant supports charitable organizations in Tarrant County, Texas, dedicated to aiding children with physical or mental disabilities. Established by the Stein sisters, this trust prioritizes organizations that provide necessary relief and treatment. Grants typically range from $10,000 to $20,000, and applicants must wait one year after receiving a grant to reapply. This ensures ongoing support for local initiatives focused on the welfare of children in need.
Children’s Mental Health Children With Disabilities Education +1 more

The Giants Foundation Grant

Giants Foundation Inc New York Football Giants
Private
Connecticut, New Jersey +1 more
Unspecified amount
The Giants Foundation Grant supports nonprofit organizations focused on community issues, health improvement, and youth empowerment. Established in 1993 by the New York Giants, the foundation aims to provide financial assistance to eligible organizations in the NY, NJ, and CT areas. Eligible applicants must be 501(c)(3) nonprofits and either youth organizations or those using funds for youth-related programming in health, education, fitness, or football. This grant fosters positive impacts in the community.
Youth Services Children’s Health & Pediatrics Physical Fitness +3 more

Newtown Savings Bank Foundation: Donation/Sponsorship Request

Newtown Savings Bank Foundation
Private
Fairfield County, Connecticut, Litchfield County, Connecticut +1 more
Unspecified amount in in-kind support
The Newtown Savings Bank Foundation supports community nonprofits with a focus on affordable housing, economic development, and financial education. Established as a 501(c)(3) organization, it prioritizes requests from organizations that serve local communities and demonstrate innovative solutions to financial need. Applications are accepted year-round, with funding directed towards initiatives that create lasting impact. The foundation encourages submissions at least 30 days before an event to ensure timely consideration.
Human & Social Services Equitable & Affordable Housing Education +3 more

State of Ohio Security Grant (OSG)

Ohio Emergency Management Agency
State/Local Government
Ohio
Up to US $125,000
The State of Ohio Security Grant (OSG) provides funding to nonprofit organizations, houses of worship, chartered nonpublic schools, and licensed preschools for security improvements. Authorized by House Bill 33, eligible organizations can apply for funding up to $125,000 per site, with a maximum request of $250,000. This grant aims to enhance security measures against potential acts of terrorism, ensuring safety and preparedness in the community.
Domestic / Homeland Security First Responders Community / Public Safety +2 more

Nancy J. Seavy Memorial Scholarship Endowment

John Randolph Foundation Inc
Private
Charles City County, Virginia, Chesterfield County, Virginia +8 more
Up to US $3,000
The Nancy J. Seavy Memorial Scholarship Endowment supports students in education and the arts, offering scholarships to those who demonstrate financial need, strong academics, and community involvement. Established in honor of Nancy J. Seavy, who championed the arts, the scholarship aims to empower individuals from the City of Hopewell and surrounding areas. Applicants must submit required documents, including transcripts and letters of recommendation, to be considered for this opportunity.
Art & Culture Writing & Literature Education +4 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.