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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,565 Results based on applied filters

James A Wharton Scholarship

Community Foundation of North Central Washington
Private
United States
Unspecified amount
The James A Wharton Scholarship, established by the Community Foundation of North Central Washington, supports students from Chelan and Douglas Counties pursuing trade education, particularly in collision repair. Open to graduating seniors and nontraditional students, this scholarship encourages enrollment in vocational programs, emphasizing a commitment to learning. Recipients may renew their scholarships by reapplying competitively, ensuring continued support for those dedicated to advancing their skills in the trades.
Mechanical Engineering Vehicle Restoration Automotive Safety +4 more

Jetton Charitable Fund Grant

Omaha Community Foundation
Private
Adair County, Iowa, Adams County, Iowa +10 more
More than US $20,000
The Jetton Charitable Fund Grant aims to enhance youth cultural education in Omaha through performing and visual arts, and natural sciences. Grants of $20,000 and more support organizations with a minimum of 5 years as 501(c)(3) nonprofits, serving over 1,000 students annually. Eligible programs focus on broad community engagement and educational initiatives. Special considerations may extend funding to organizations in Lincoln and across Nebraska and Southwest Iowa, emphasizing programmatic support with some capacity building exceptions.
Environmental Education Art Education Youth Involvement in the Arts +4 more

Frankenthaler Climate Initiative: Scoping Grants

Helen Frankenthaler Foundation Inc
Private
American Samoa, Guam +4 more
Up to US $25,000
The Frankenthaler Climate Initiative provides funding for energy efficiency projects in visual arts museums, addressing climate change through innovative cultural leadership. Grants up to $25,000 support institutions in evaluating energy mitigation opportunities, enhancing efficiency, and reducing emissions. Eligible applicants include museums and visual arts schools across the U.S. The initiative encourages sustainable practices while assisting organizations in understanding their energy needs and planning for effective interventions within a project timeline of 18 months.
Climate Change Resilience & Equity Renewable/Sustainable Energy Museums & Cultural Institutions +2 more

Frankenthaler Climate Initiative- Implementation Grants

Helen Frankenthaler Foundation Inc
Private
American Samoa, Guam +4 more
Up to US $100,000
The Frankenthaler Climate Initiative offers implementation grants aimed at enhancing energy efficiency in visual arts museums, addressing climate change through innovative projects. With deadlines extended for those affected by the LA Fires, eligible institutions can apply for funding ranging from $50,000 to $100,000. This initiative supports museums of all sizes, helping them reduce emissions and operational costs while promoting sustainable practices in the arts sector.
Climate Change Resilience & Equity Renewable/Sustainable Energy Museums & Cultural Institutions +2 more

California Career Technical Education Incentive Grant

California Department of Education
State/Local Government
California
Unspecified amount
The California Career Technical Education Incentive Grant (CTEIG) aims to enhance career technical education for students from kindergarten through grade twelve. This initiative, supported by the California Department of Education, focuses on equipping students with essential skills for employment and further education. By fostering collaboration among educators and community partners, CTEIG seeks to improve educational outcomes and workforce readiness, ensuring that students thrive in a diverse and interconnected society.
Workforce Preparation & Job Readiness Career / College Preparation Education +1 more

GMF: Cycle 2 - Capital Support

Greater Milwaukee Foundation Inc
Private
Milwaukee County, Wisconsin, Ozaukee County, Wisconsin +2 more
Up to US $150,000
The Greater Milwaukee Foundation's GMF: Cycle 2 - Capital Support grant offers funding to 501(c)(3) organizations and governmental agencies that promote community impact, focusing on racial equity and inclusion. With a maximum of $50,000 available per year for three years, this initiative supports projects in early childhood education, mental health, and workforce development, all aimed at enhancing economic mobility and addressing systemic disparities in the Milwaukee area.
Employment Services Job Creation Health Disparities & Social Determinants of Health +2 more

Arizona SFY25 AmeriCorps State Formula Grant

Arizona Governor's Office of Youth, Faith and Family
State/Local Government
Arizona
US $100,000 - US $500,000
The Arizona SFY25 AmeriCorps State Formula Grant, managed by the Governor's Office of Youth, Faith and Family, offers between $100,000 and $500,000 to support programs engaging AmeriCorps members in impactful community services. Eligible applicants include local governments, non-profits, and educational institutions. This program addresses critical needs in areas such as disaster services and education, with approximately $4 million available in total funding. Note that the next grant request is expected in Winter 2027.
Education Military & Veterans Services Disaster Relief / Humanitarian Aid +4 more

Anna Paulina Grant

Anna Paulina Foundation
Private
Michigan
US $100,000 - US $300,000
The Anna Paulina Foundation, established in 1961, is dedicated to supporting public charities in Michigan, particularly in the Flint area. With a focus on the arts, youth leadership, urban beautification, and human services, the Foundation aims to make a positive impact on the community. Grants range from $100,000 to $300,000, with larger awards available in special cases, ensuring support for specific programs and projects.
Music Youth Development & Leadership Youth Involvement in the Arts +2 more

North Dakota Community Development Block Grant (CDBG) (ND)

North Dakota Department of Commerce
State/Local Government
North Dakota
More than US $75,000
The North Dakota Community Development Block Grant (CDBG) Program provides essential financial support to local governments for public facilities, housing rehabilitation, and economic development projects aimed at assisting very low and low-income individuals. Projects funded may include housing rehabilitation, public facility improvements, and economic initiatives that create job opportunities. Ensuring compliance with national objectives, the program promotes community development and addresses urgent needs while enhancing the living conditions of residents.
Community Development & Revitalization Economic Services & Development Public Infrastructure +1 more

Stand Together Foundation Grant

Greater Green Bay Community Foundation
Private
Brown County, Wisconsin, Kewaunee County, Wisconsin +1 more
Up to US $225,000
The Stand Together Foundation Grant, funded by the Greater Green Bay Community Foundation, aims to support nonprofit organizations in their efforts to alleviate poverty. The grant prioritizes projects that enhance housing stability, education, workforce development, and human services. Eligible applicants must serve the greater Green Bay area and demonstrate a commitment to non-discrimination. Innovative proposals addressing root causes of poverty will be highly considered, with multiyear requests also welcome.
Real Estate & Housing Basic Human Needs Poverty Alleviation & Services +2 more

Amicus Foundation Grant

Amicus Foundation
Private
Montana
Unspecified amount
The Amicus Foundation, established in 2015, is dedicated to supporting non-profit organizations that focus on families, faith, conservation, health, veterans, and education. Through matching grants, the foundation aims to maximize impact by aligning financial resources with effective charitable initiatives. Their mission is to foster a healthy family environment, which they believe is essential for the success of the nation. The foundation emphasizes strategic investments to ensure positive outcomes for communities.
Military & Veterans Services Environmental Conservation Religion & Spirituality +4 more

Massachusetts Manufacturing Accelerate Program (MMAP)

Massachusetts Technology Education Engineering Collaborative
Private
Massachusetts
Up to US $300,000
The Massachusetts Manufacturing Accelerate Program (MMAP) aims to support small- and medium-sized manufacturers in modernizing their operations and adopting new technologies. This initiative, managed by the Mass Tech Collaborative, provides grant funding and accelerator support to help eligible businesses navigate the challenges of a rapidly evolving manufacturing landscape. By conducting thorough assessments, the program identifies effective capital investments to meet the specific needs of participating manufacturers, fostering economic growth and job creation in Massachusetts.
Workforce Preparation & Job Readiness Robotics Artificial Intelligence (AI) +1 more

Elisabeth Severance Prentiss Foundation Grant

E S Prentiss Foundation
Private
Cuyahoga County, Ohio, Geauga County, Ohio +3 more
Unspecified amount
The Elisabeth Severance Prentiss Foundation Grant supports healthcare initiatives in the greater Cleveland area, focusing on medical research, public health promotion, and assistance to local hospitals. The foundation prioritizes grant requests from private sector organizations and favors projects with a duration of three years or less. It does not fund national campaigns, individual scholarships, or endowment contributions. Eligible projects must align with the foundation's commitment to enhancing health services for all, particularly low-income populations.
Health & Medicine Epidemiology & Public Health Surgery +2 more

Edward J. Byrne Memorial Justice Assistance Grant, Maryland

Maryland Governor’s Office of Crime Prevention, Youth, and Victim Services
State/Local Government
Maryland
US $10,000 - US $100,000
The Edward J. Byrne Memorial Justice Assistance Grant in Maryland supports vital criminal justice initiatives aimed at enhancing community safety. It provides essential funding to address gaps in services related to violent crime, victim assistance, law enforcement, and rehabilitation. Managed by the Governor's Office of Crime Prevention, Youth, and Victim Services, this grant encourages public input on its draft application, fostering community involvement in shaping effective crime prevention strategies.
Gun Violence Prevention Violence Prevention Community / Public Safety +3 more

Louder Than Words Grant Program

Finish Line Youth Foundation Inc
Corporate
United States
Up to US $10,000
The Louder Than Words Grant Program, supported by the Finish Line Youth Foundation, focuses on empowering diverse and underserved communities in Indianapolis and beyond. With grant cycles addressing areas like health, workforce development, and safe communities, organizations can request up to $10,000 to support impactful programming. Eligible applicants must be 501(c)(3) organizations dedicated to fostering positive change, particularly for communities of color, ensuring equitable access to resources and opportunities.
Healthy Habits & Behaviors Wellness & Healthy Living Community / Public Safety +1 more

The Talegaonkar Medical Scholarship Endowment

John Randolph Foundation Inc
Private
Chesterfield County, Virginia, Hopewell City, Virginia +1 more
Up to US $1,500
The Talegaonkar Medical Scholarship Endowment, established by Dr. Talegaonkar in 2001, aims to support aspiring Registered Nurses and Physicians in Virginia. This scholarship helps cover tuition and educational costs for students attending higher learning institutions, particularly Virginia Commonwealth University. Applicants must demonstrate financial need and maintain a GPA of 3.5 or above. The scholarship committee reviews applications annually, ensuring a fair selection process while encouraging local students to pursue essential healthcare careers.
Chemistry Physics Biology +4 more

Gerald A. & Darlene R. Schaffer Fund

Sheridan County Community Foundation
Association/Society
Sheridan County, Kansas
Unspecified amount

Sheridan County Community Foundation

The Sheridan County Community Foundation is an Affiliate Foundation of Greater Northwest Kansas Community Foundation with all funds managed by GNWKCF.

The Foundation became an affiliate of GNWKCF in 2012. An affiliate is a collection of community funds to increase philanthropic giving in a geographic area. Both endowed and non-endowed funds are developed to provide financial support to 501(c)(3) and other qualifying nonprofit organizations and for charitable purposes to benefit area residents. The mission of Sheridan County Community Foundation is to encourage, prudently manage, and distribute charitable contributions to improve the quality of life in Sheridan County residents, now and in the future.

Gerald A. & Darlene R. Schaffer Fund

The Gerald A. & Darlene R. Schaffer Fund provides grant support to assist organizations or community projects that benefit Hoxie and/or Sheridan County in the following categories or entities as specified: Healthcare needs in Sheridan County; Education in Sheridan County (Hoxie Schools specific); Music, arts, and entertainment opportunities (Hoxie specific); City of Hoxie Golf Course; Hoxie Elks Projects; St. Frances Cabrini Catholic Church; and St. Frances Catholic Cemetery. Grantmaking decisions are overseen by the Sheridan County Community Foundation Board of Directors.

Community Development & Revitalization Health Disparities & Social Determinants of Health Educational Access & Equity +3 more

Radio Systems Corporation Grant

Radio Systems Corporation
Corporate
Anderson County, Tennessee, Blount County, Tennessee +6 more
Unspecified amount
The Radio Systems Corporation Grant aims to enhance animal welfare and support youth development by allocating a portion of corporate profits to charitable organizations. Eligible applicants must be located in Knox County and the surrounding eight counties in Tennessee. The grant prioritizes shelters, rescues, and training centers, focusing on initiatives that benefit both animals and young people in the community. This commitment reflects Radio Systems Corporation's dedication to giving back and fostering a positive impact.
Animal Welfare - Domestic Animals & Pets Education - Higher Education Education - High School +3 more

David W. Moore Memorial Scholarship

Stanislaus Community Foundation
Private
United States
US $2,500

Stanislaus Community Foundation provides scholarship opportunities for students in order to help them achieve their educational and career goals. We believe that by investing in our students, we are investing in a brighter future for Stanislaus. 

David W. Moore Memorial Scholarship

Open to graduating seniors from Atwater, Golden Valley and Oakdale pursuing a degree in agriculture, ag-related fields, animal science or teaching or primary healthcare. Students must demonstrate financial need, community involvement and have a 2.5+ GPA.

Award Amount:

  • $2,500
Education - Higher Education Career / College Preparation Education +3 more

ESC IDEA-B and State Dyslexia and Related Disorders Coordinators

Texas Education Agency
State/Local Government
Texas
Unspecified amount
The Texas Education Agency (TEA) is offering the 2025-2026 ESC IDEA-B and State Dyslexia and Related Disorders Coordinators grant to provide essential technical assistance and training for dyslexia services across 20 Regional Education Service Centers in Texas. This initiative aims to ensure compliance with federal and state regulations, including the Individuals with Disabilities Education Act (IDEA) and Texas Education Code 38.003, enhancing educational support for affected students.
Education Speech-Language Learning & Disorders Educational Access & Equity +1 more

Hartford Area Community Foundation Grant

Sioux Falls Area Community Foundation
Private
Minnehaha County, South Dakota
Unspecified amount

Sioux Falls Area Community Foundation

Founded in 1984, we are a 501(c)(3) public charity. Today, we manage more than 1,000 charitable funds, serving as the trusted stewards for more than $390 million in assets.

Our Community Investment team works with local nonprofits, schools and community leaders to identify gaps, assess critical needs and explore opportunities and possibilities.

Our Philanthropy team works with individuals, families, advisors, businesses, and nonprofits, offering deep and broad experience and expertise in philanthropic strategy, charitable and organizational endowments, and legacy planning.

As a Foundation, we connect donors with causes that inspire them. We invest and steward their gifts to amplify their generosity and create an even greater impact.

We’re proud to say that in collaboration with our donors, we've granted more than $350 million to nonprofits and causes throughout our area since our founding.

Hartford Area Community Fund

The Hartford Area Community Fund is a charitable endowment established to enhance the vibrancy of our community and improve the quality of life for those who call this special place home. Gifts to the fund grow over time thanks to the benefit of a pooled investment that generates long-term asset growth.

Each year, the board awards grants in support of local nonprofits and community-based projects and ideas. Organizations who serve our youth and senior citizens, as well as those dedicated to important causes such as education, the arts, cultural enrichment, health and safety, and more are all made stronger thanks to support from the Hartford Area Community Fund.

Senior Services Youth Services Educational Access & Equity +3 more

ESC IDEA-B Sensory Impairments

Texas Education Agency
State/Local Government
Texas
US $1,415,000
The 2025-2026 ESC IDEA-B Sensory Impairments program, administered by the Texas Education Agency, aims to enhance support for local educational agencies. It focuses on improving educational outcomes for students with visual impairments, including those who are blind or deafblind. The program provides essential technical assistance and training for educators, as well as funding for certified interpreters, ensuring effective communication and access to resources for teachers at the Texas School for the Deaf.
Education Educational Access & Equity Children With Disabilities +2 more

Abandoned Mine Land Economic Revitalization (AMLER) Program

Ohio Department of Natural Resources
State/Local Government
Ohio
US $100,000 - US $2,000,000
The Abandoned Mine Land Economic Revitalization (AMLER) Program, administered by the Ohio Department of Natural Resources, addresses abandoned mine lands in Appalachia. This initiative provides crucial funding for reclamation efforts that promote both environmental restoration and local economic development. Since 2017, Ohio has received over $100 million to revitalize communities affected by mining. The program targets areas with significant unfunded AML issues, fostering sustainable growth and enhancing community well-being.
Economic Services & Development Environmental Contamination & Pollution Waste Management +1 more

OKC Living Classroom Grant Program

Oklahoma City Zoo
Private
Canadian County, Oklahoma, Cleveland County, Oklahoma +8 more
Up to US $1,500
The OKC Living Classroom Grant Program aims to combat the decline of monarch butterflies, which have seen an 80% population drop due to habitat loss. This initiative, led by the Oklahoma City Zoo and partners, provides funding and resources to K-12 schools in the Oklahoma City metro area to create gardens that include essential milkweed and nectar plants. Schools will receive professional development, financial support, and curriculum materials to foster environmental education and conservation efforts.
Entomology Botanical Conservation Horticulture & Gardening +2 more

WCGMF Rapid Response Grants

William Caspar Graustein Memorial Fund
Private
Connecticut
Up to US $10,000
The WCGMF Rapid Response Grants are designed to support organizations and individuals in Connecticut who confront systemic oppression through community-building and education. These grants aim to foster healing and inclusion while opposing hatred and divisiveness. Funding will be allocated swiftly to aid local groups in their advocacy efforts, ensuring timely support for critical initiatives that promote equity and well-being.
Social Justice / Human Rights Racial / Ethnic Justice & Rights Women's Rights & Equality +2 more

Oconomowoc Area Foundation Grants

Oconomowoc Area Foundation
Private
Waukesha County, Wisconsin
Unspecified amount
The Oconomowoc Area Foundation, established in 2002, supports local charitable initiatives within the Oconomowoc Area School District. It prioritizes programs for children and youth, elderly support, environmental preservation, and community enrichment through arts and culture. Eligible organizations include nonprofits, schools, and municipal agencies providing services to local residents. The foundation aims to foster community well-being and sustainable development by funding impactful projects that enhance educational outcomes and support those in need.
Environmental Conservation Disaster Relief / Humanitarian Aid Child Care Services +2 more

Fiscal Year 2026 Flood Mitigation Assistance

US Department of Homeland Security: Federal Emergency Management Agency (FEMA)
Federal Government
American Samoa, Guam +4 more
US $20,000,000 - US $260,000,000
The Fiscal Year 2026 Flood Mitigation Assistance (FMA) program offers federal funds aimed at reducing flood risks for buildings insured by the National Flood Insurance Program. This initiative supports states, U.S. territories, and local governments in implementing various flood mitigation activities, thereby lessening the financial burden on the NFIP. FEMA prioritizes applications that enhance multistate or regional capabilities, contributing to a safer infrastructure and community resilience against flooding.
Environmental Conservation Community Development & Revitalization Climate Change Resilience & Equity +1 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.