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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,629 Results based on applied filters

Pat Shinobu Scholarship Fund

Hawai'i Community Foundation
Private
United States
Unspecified amount
The Pat Shinobu Scholarship Fund, established in 2015 by the Hawai‘i Community Foundation, aims to support students from Hawai‘i pursuing higher education. Eligible applicants must be full-time undergraduate students with a minimum GPA of 2.7, demonstrate financial need, and provide a recommendation letter. Preference is given to public high school graduates from Hawai'i Island and previous recipients who maintain eligibility. This fund fosters educational opportunities and equity within the community.
Academic Success & Enrichment Academic Scholarship Programs

Danville/Pittsylvania Academy of Medicine Alliance Scholarship

The Community Foundation Of The Dan River Region
Private
Danville City, Virginia, Pittsylvania County, Virginia
Unspecified amount

About

The Community Foundation of the Dan River Region is an independent, public charity established in September 1996 by a steering committee of local civic leaders to gather permanent funds to support our area.

The Foundation’s service area now includes Danville, Pittsylvania and Halifax counties in Virginia as well as Caswell County, NC.

Scholarship Information

Currently, The Community Foundation administers 75 separate endowed scholarship funds. Established by individuals or organizations, these funds help area students achieve their academic and career-oriented goals.

Scholarships through the Community Foundation support individuals of all ages who reside within the Dan River Region – Danville, VA; Pittsylvania and Halifax counties, VA; and Caswell County, NC. In 2025, we awarded more than $370,000 to 152 students.

Danville/Pittsylvania Academy of Medicine Alliance Scholarship

Open applications for Danville and Pittsylvania County graduates who are pursuing medical fields of study.

Education - Higher Education Medical Education & Professional Training

Aurand Harris Grants & Fellowships

Children's Theatre Foundation of America (CTFA)
Private
United States
US $2,000 - US $3,000
The Aurand Harris Grants & Fellowships support children’s theatre by funding projects that foster artistic growth and promote diversity, equity, and inclusion. Eligible applicants include 501c3 nonprofit theatres and individual artists. The grants cover various expenses, such as fees for artists and equipment costs, while prioritizing projects that align with the values of the Children's Theatre Foundation of America. Notably, funding will not cover general operating support or projects already in progress.
Theater

Warren MacKenzie Advancement Award

Northern Clay Center
Private
United States
Up to US $2,000
The Warren MacKenzie Advancement Award supports students and emerging ceramic artists in the U.S. to enhance their skills and knowledge through research and education for up to twelve months. Eligible applicants include current students and recent graduates in ceramics. The award offers a maximum of $2,000 for travel, education, or research, enabling recipients to explore new techniques, collaborate with mentors, and attend workshops, thereby fostering professional growth in the field of ceramics.
Fine Art

African American Cultural Heritage Action Fund Grants

National Trust for Historic Preservation
Private
United States
US $50,000 - US $150,000
The African American Cultural Heritage Action Fund Grants support the preservation of historic sites that reflect African American cultural heritage. Grants ranging from $50,000 to $150,000 assist projects in areas like Capital Projects, Organizational Capacity Building, Project Planning, and Programming. Eligible applicants include public agencies, accredited colleges, and nonprofits. The program emphasizes themes such as activism, innovation, and historically significant sites, aiming to foster a deeper understanding and appreciation of African American history.
Black American Culture & Heritage

Non-Profit $2,000 Promotional Event Grant (FL)

Franklin County Tourist Development Council
State/Local Government
Franklin County, Florida
US $2,000
The Non-Profit $2,000 Event Promotions Grant by the Franklin County Tourist Development Council supports eligible 501c non-profits and governmental organizations in promoting one-day events. This reimbursement grant aims to help local organizations effectively market their events through various promotional activities, including media outreach. Eligible applicants must have been operational for at least two years and conduct events in Franklin County, ensuring community-focused engagement and visibility.
Tourism

RCF: Summertime Kids Grants

Richland County Foundation
Private
Richland County, Ohio
US $250 - US $2,500
The Richland County Foundation offers Summertime Kids Grants, aimed at nonprofit agencies to provide engaging and safe summer activities for children in Richland County. Established in 1945, the foundation is dedicated to improving community life through strategic philanthropy. While funding supports direct programming, it does not cover regular staffing or operational costs. This initiative ensures that children have access to enjoyable summer experiences, fostering growth and development in a supportive environment.
After School / Summer Educational Programs

Harvard Allston Partnership Fund (Up to $10,000)

President And Fellows Of Harvard College
Private
Suffolk County, Massachusetts
Up to US $10,000
The Harvard Allston Partnership Fund offers annual grants of up to $10,000 to non-profit organizations and community groups that serve the Allston-Brighton community. Established in collaboration with local stakeholders, the fund aims to support neighborhood improvement, cultural enrichment, and education projects. With a total of $200,000 available, priority is given to initiatives that demonstrate a measurable impact and address local needs, including youth programs and public health initiatives.
Community Culture & Heritage Education Community Development & Revitalization

The Health Foundation: Challenge Grants

The Health Foundation
Association/Society
Wilkes County, North Carolina
Unspecified amount
The Health Foundation's Challenge Grants aim to enhance health and well-being in Wilkes County, North Carolina, by promoting community-driven solutions that tackle health equity and social determinants of health. These grants support organizations in developing sustainable fundraising programs to meet identified healthcare needs. Eligible applicants include non-profits and governmental entities, while funding is not available for religiously affiliated services. The program encourages innovative approaches to health improvement in the local community.
Health Disparities & Social Determinants of Health Nonprofit Growth & Development

Traditional Grant for Schools

Edward E. Ford Foundation
Private
United States
US $25,000 - US $100,000
The Edward E. Ford Foundation offers Traditional Grants to independent schools in the U.S. for projects that enhance educational opportunities. With over $118 million granted since its inception, the Foundation emphasizes the importance of matching funds, requiring a dollar-for-dollar commitment from schools. Eligible institutions must serve grades 9-12, be NAIS members, and have a qualified Head of School. Applications are considered during the June and November Agendas, supporting diverse educational initiatives.
Education - High School

Fairs Capital Improvement Grant Program

Commonwealth of Pennsylvania
State/Local Government
Pennsylvania
Up to US $25,000
The Fairs Capital Improvement Grant Program in Pennsylvania offers grants up to $25,000 for certified agricultural fairs to improve their fairgrounds. Projects must include a dollar-for-dollar cash match from the fair, ensuring that funds are used for permanent improvements such as construction, renovation, and utility upgrades. This program aims to enhance the facilities that support the agricultural community, promoting sustainability and improving visitor experiences at fairs.
Agriculture Parks & Public Spaces

IN Agricultural Conservation Easement Program (ACEP): Wetland Reserve Easements (WRE)

USDA: Natural Resource Conservation Service of Indiana
State/Local Government
Indiana
Unspecified amount
The IN Agricultural Conservation Easement Program (ACEP) offers financial and technical support to private landowners and Indian tribes for restoring and protecting wetlands through various easement options. These include permanent and 30-year easements, where NRCS covers most costs including easement values and restoration. Benefits include improved wildlife habitats, enhanced water quality, and resilience to climate change. This program is available year-round, ensuring ongoing support for eligible landowners.
Land / Habitat Conservation

Small Business Development Grant (WI)

Wisconsin Economic Development Corporation (WEDC)
State/Local Government
Wisconsin
US $50,000 - US $250,000
The Small Business Development Grant (SBDG) in Wisconsin aims to enhance local economies by providing financial support to small business development organizations. With awards ranging from $50,000 to $250,000, the program targets local and regional Economic Development Organizations, municipalities, tribal governments, and counties to foster innovative support for small businesses. This initiative addresses the ongoing challenge of accessing capital, encouraging diverse and rural business growth while ensuring community involvement in program development.
Business Development

Retail Food Safety Regulatory Association Collaboration CAP (356048)

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $4,000,000
The Retail Food Safety Regulatory Association Collaboration CAP aims to enhance retail food protection in the U.S. by renewing a cooperative agreement that promotes collaboration among non-profit organizations and educational institutions. This initiative focuses on reducing food-borne illnesses through research and the advancement of best practices in retail food safety. By leveraging local and state resources, the program seeks to effectively mitigate food safety risks and improve public health outcomes.
Food Safety

Washington Recreational Trails Grant Program

Washington State Recreation and Conservation Office
State/Local Government
Washington
Up to US $150,000
The Washington Recreational Trails Grant Program funds the rehabilitation and maintenance of trails, ensuring a backcountry experience free from human development. It supports diverse trail activities including hiking, biking, and motorized recreation. Typical projects involve clearing trails, repairing damage from natural events, and enhancing trail facilities. Grants are available up to $150,000, with a commitment to maintain facilities for 25 years. This initiative promotes environmental compliance and is open to various agencies and organizations.
Trail Creation & Maintenance

Animal Food Regulatory Program Standards Implementation Development and Maintenance, with Mutual Reliance Initiatives

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $10,600,000
The Animal Food Regulatory Program Standards Implementation Development and Maintenance initiative aims to foster a cohesive national animal food safety system. This funding opportunity supports state programs in implementing the Animal Feed Regulatory Program Standards (AFRPS) and encourages mutual reliance between federal and state regulatory efforts. Key outcomes include enhanced operational standards and improved integration of regulatory processes, ultimately contributing to a safer food supply and better animal health across jurisdictions.
Animal Food & Drug Safety

Federal Recreational Trail Program

Minnesota Department of Natural Resources
State/Local Government
Minnesota
US $2,500 - US $150,000
The Federal Recreational Trail Program, managed by the Minnesota Department of Natural Resources, aims to enhance motorized and non-motorized trails through financial support. Eligible projects include trail maintenance, development, and educational programs. A 25% match is required for funding requests ranging from $2,500 to $150,000, with completion deadlines set for June 30, 2025. This initiative prioritizes projects involving local partnerships and environmental sustainability.
Trail Creation & Maintenance

Lebbeus F. Bissell Scholarship Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $4,000
The Lebbeus F. Bissell Scholarship Fund, established in 1971 by Lebbeus F. Bissell, offers scholarships to graduating high school seniors from Rockville, Ellington, and Tolland, Connecticut. Managed by the Hartford Foundation for Public Giving, which has awarded nearly $30 million since 1945, this fund aims to support local students in their pursuit of higher education. Typically, 3-4 awards are granted annually, focusing on those with financial need and strong community involvement.
Education - Higher Education Academic Scholarship Programs

Laurel M. Cohn Scholarship Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $5,000
The Laurel M. Cohn Scholarship Fund, established by the Hartford Foundation for Public Giving, supports scholarships for graduating high school seniors in the Greater Hartford area. Candidates must pursue a degree in business, economics, or a related field at an accredited four-year institution. With a history of awarding nearly $30 million in scholarships since 1945, this fund aims to empower motivated students with financial needs to achieve their educational goals.
Education - Higher Education Academic Scholarship Programs

Paul Keyes Memorial Scholarship

Community Foundation for the Fox Valley Region
Private
Wisconsin
US $500
The Paul Keyes Memorial Scholarship honors a dedicated individual who participated in various sports and served in the Navy. Established by his family, this scholarship supports students pursuing careers in skilled trades, reflecting Paul's belief in the importance of trade professions. A single, non-renewable award of $500 will assist with educational costs for students enrolled in accredited programs in Wisconsin. This initiative aims to inspire future generations to excel in their trades.
Vocational & Trade Education Academic Scholarship Programs

KJ Foster Memorial Scholarship Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $1,000 - US $1,500
The KJ Foster Memorial Scholarship Fund, established by the Hartford Foundation for Public Giving, honors Kerry "KJ" Foster, Jr., a promising student lost to gang violence. The scholarship supports high school graduates from the Greater Hartford region who demonstrate academic potential, financial need, and community involvement. Since 1945, the Hartford Foundation has awarded nearly $30 million in scholarships, helping local students pursue higher education and achieve their academic goals.
Education - Higher Education Academic Scholarship Programs

Michael J. O’Brien Scholarship

Community Foundation for the Fox Valley Region
Private
Brown County, Wisconsin, Dane County, Wisconsin +12 more
US $700
The Michael J. O’Brien Scholarship honors the legacy of Dr. Michael O’Brien, a dedicated educator and author from Green Bay, WI. This $700 non-renewable scholarship supports students pursuing degrees in history, political science, or international relations at a UW institution. Eligible candidates must maintain part-time or full-time enrollment. The scholarship, established in memory of Michael by his family, aims to recognize individuals with outstanding character and leadership, reflecting his commitment to education and mentorship.
History Political Science Academic Scholarship Programs

The Coolidge Scholarship

Calvin Coolidge Presidential Foundation
Association/Society
United States
Unspecified amount
The Coolidge Scholarship is a prestigious, full-ride scholarship for undergraduate students in the U.S., covering tuition, room, board, and expenses for four years. It is open to high school juniors from all backgrounds, promoting academic excellence and interest in public policy. Recipients are selected through a rigorous process involving interviews at the Coolidge Historic Site. The program also includes a senators' summit for top applicants, fostering connections among high-achieving students.
Education - Higher Education Academic Scholarship Programs

Junior League Of Collin County Agency Assistance Fund

Junior League Of Collin County
Private
Collin County, Texas
Unspecified amount
The Junior League of Collin County Agency Assistance Fund supports local non-profits and government agencies in Collin County by providing financial assistance for short-term program support and emergency needs. Eligible organizations must be 501(c)(3) certified and established for at least two years. The fund prioritizes requests addressing critical human needs and those from agencies that have not previously received assistance this fiscal year, fostering community impact through collaboration and volunteerism.
Basic Human Needs Disaster Relief / Humanitarian Aid

Families First Community Grants

Tennessee Department of Human Services
State/Local Government
Tennessee
Unspecified amount
The Families First Community Grants, administered by the Tennessee Department of Human Services, aim to empower low-income families by facilitating access to employment and essential support services. Through collaboration with local non-profits, this initiative seeks to enhance independence and self-sufficiency among families across Tennessee, fostering a stronger community. Organizations that align with this mission are encouraged to apply and partner in this transformative effort.
Family Services Poverty Alleviation & Services

Public Water Access Sites - Partnership Funding

Minnesota Department of Natural Resources
State/Local Government
Minnesota
Unspecified amount
The Public Water Access Sites Partnership Funding program offers essential financial and technical support for public water access and state water trail projects. This initiative prioritizes repairs, rehabilitation, and the development of new facilities, including access sites and state water trail campsites. Eligible applicants include local government units such as counties and townships, enhancing public access to water resources across Minnesota.
Recreational Water Use & Boating

Animal Food Regulatory Program Alliance

US Department of Health & Human Services: Food and Drug Administration (FDA)
Federal Government
United States
US $600,000
The FDA/ORA's Cooperative Agreement Program aims to enhance the national food safety system through collaboration among federal and state agencies. Key objectives include building an integrated animal food safety system, sharing best practices, and promoting training programs for animal food safety. This initiative supports the Animal Food Regulatory Program Standards (AFRPS) and ensures ongoing improvements to meet modern regulatory needs. Eligible applicants must represent state animal food regulatory programs at a national level.
Animal Food & Drug Safety

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.