Upcoming Webinar
Instrumentl Fall Launch: Your Grant Operating System Has Leveled Up.
Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$9.00B

Total funding

$6K

Median grant

32,000+ grants
$9.00B total
$6K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

32,423 Results based on applied filters

Collins C. Diboll Private Foundation Grant

Collins C. Diboll Private Foundation
Private
Orleans Parish, Louisiana
US $1,000 - US $250,000
The Collins C. Diboll Private Foundation, established in 1984, focuses on charitable and educational initiatives for the New Orleans community. It provides grants ranging from $1,000 to $250,000 annually to 501(c)(3) organizations that address societal issues and promote arts, education, and health. While primarily supporting local organizations, it may consider applications from other areas. However, it does not fund scholarships, grants to individuals, or for-profit entities.
Education - Higher Education Art & Culture

Roots & Resilience Artist Grant

The Doan Foundation
Association/Society
Imperial County, California, Kern County, California +8 more
US $1,000

About

THE DOAN FOUNDATION is a 501(c)(3) nonprofit dedicated to uplifting the overlooked—underserved youth, emerging creatives, and grassroots cultural organizations. Through scholarships, artist grants, and cultural sponsorships, we provide access, resources, and recognition to those too often unseen. By investing in creativity as a force for healing, identity, and community, we ensure that the arts remain vital, visible, and accessible across Southern California.

Roots & Resilience Artist Grant

This grant provides artists or arts & culture organizations from Southern California with $1,000 each to bring impactful projects to life – projects that address social issues, mental health, uplift underrepresented voices, and inspire healing and connection within communities. By investing in these creatives, The Doan Foundation aims to preserve powerful stories, strengthen cultural understanding, and drive change.

The Roots & Resilience Artist Grant Program reflects our commitment to empowering artists as changemakers, using their craft to inspire and unite us all.

Together, we’re building a brighter future through the transformative power of art.

Art & Culture Arts / Culture Access & Participation

IAC Arts Project Support Grant

Indiana Arts Commission
State/Local Government
Indiana
Up to US $4,000
The IAC Arts Project Support Grant offers funding for Indiana 501(c)3 nonprofits and public entities to carry out specific arts projects or activities. Applicants can propose diverse projects like art events, performances, exhibitions, or workshops that foster public engagement, especially in underserved communities. This initiative, supported by the Indiana Arts Commission, aims to enhance access to quality arts experiences and support local artists, enriching Indiana's cultural landscape without a match requirement.
Art & Culture Arts / Culture Access & Participation

Mary Josephine Bloder Scholarship Fund

Hawai'i Community Foundation
Private
Hawaii
Unspecified amount
The Mary Josephine Bloder Scholarship Fund, established by a dedicated teacher, supports Lahainaluna High School boarding students who excel in science. This renewable scholarship aims to assist those in financial need while maintaining a minimum GPA of 2.0. Eligible applicants must submit two letters of recommendation, including one from a science teacher at the school, ensuring that past recipients can reapply if they continue to meet the criteria.
Science Academic Scholarship Programs

Quiet Inspiration Award

Santa Fe Community Foundation
Private
Mora County, New Mexico, Rio Arriba County, New Mexico +2 more
Unspecified amount
The Quiet Inspiration Award, presented by the Santa Fe Community Foundation, recognizes nonprofits in northern New Mexico that have quietly made impactful contributions to their communities over at least three years. The award celebrates organizations that build trust and support among diverse groups while aligning with the Foundation's funding priorities. Nominations are open until May 8, 2026, inviting all community members to honor these vital contributors.
Community Services Economic Services & Development

Monroe County Bar Association Scholarship

Community Foundation of Monroe County
Private
Monroe County, Michigan
Unspecified amount

Scholarship Opportunities

We award over 120 scholarships each year to Monroe County residents. Whether you’re heading to college, pursuing a technical career, or furthering your education as an adult, there’s a scholarship for you.

Monroe County Bar Association Scholarship

For Monroe County graduates attending an accredited law school in the United States.

Academic Scholarship Programs Law

Dream Big Technology Grant

Kindcause Inc.
Private
United States
Unspecified amount
The Dream Big Technology Grant by KindCause.org aims to empower registered 501(c)(3) organizations by funding the implementation of Salesforce CRM. This initiative enhances nonprofit operations, enabling better donor management and campaign efficiency. With automated workflows and integrated tools, nonprofits can improve fundraising efforts and save valuable resources. Successful applicants will receive tailored technology roadmaps and potential funding for essential packages, ensuring they maximize their impact in the community.
Emerging Technology Development Cyberinfrastructure

Judge Paul Rosenblatt Scholarship

Arizona Community Foundation
Private
Arizona
Unspecified amount

Arizona Community Foundation

For more than four decades, the Arizona Community Foundation has worked in tandem with generous individuals, families, and organizations to address some of the biggest challenges facing our state.

Scholarships

In partnership with our generous donors, we award millions of dollars annually to help students achieve their educational goals. Through our online system, students complete one application and are matched with available scholarships, based on their eligibility requirements.

Judge Paul Rosenblatt Scholarship

The Judge Paul Rosenblatt Scholarship is open to any law student at the University of Arizona from Yavapai County.

Education - Higher Education Law

ISF Law Scholarship Program

Islamic Scholarship Fund
Association/Society
United States
US $5,000 - US $10,000
The ISF Law Scholarship Program, established by the Islamic Scholarship Fund, aims to improve access to justice for Muslims in America. Since 2009, it has provided scholarships ranging from $5,000 to $10,000 to support students in law and public interest fields. The program seeks to enhance American Muslim representation in policy-making and media, ensuring their voices are heard. Eligible applicants include full-time students or part-time students working in ISF-supported fields, maintaining a minimum GPA of 3.0.
Public Policy Law

Medical Scientist Training Program (MSTP)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Medical Scientist Training Program (MSTP) aims to cultivate skilled clinician-scientist leaders to meet the nation's biomedical research demands. It supports domestic organizations in developing dual-degree training that integrates clinical and research education, leading to both a clinical degree (e.g., M.D., D.O.) and a Ph.D. Through comprehensive mentoring and career development, MSTP prepares trainees for impactful careers in health-related research, ensuring a robust pipeline of qualified scientists.
Science Medical Education & Professional Training

Amgen Foundation Grants

The Amgen Foundation Inc
Corporate
Alameda County, California, Contra Costa County, California +18 more
Unspecified amount
The Amgen Foundation, established in 1990, focuses on enhancing science education and strengthening communities. It supports nonprofit organizations that align with its mission, emphasizing teacher development and hands-on science experiences. Grants are awarded annually, with a commitment of $180 million to impactful programs. Eligible organizations include public schools and libraries, while ineligible requests involve individual support, religious organizations, and political activities. This approach aims to inspire the next generation of innovators through quality educational opportunities.
STEM / STEAM Education Community Services

Getty Scholars Program at the Villa

Getty Foundation
Association/Society
Los Angeles County, California
More than US $21,500
The Getty Scholars Program at the Villa supports distinguished researchers in arts and humanities, allowing them to conduct advanced research on antiquity's cultural heritage. Scholars engage with the Getty's extensive collection and a vibrant community of professionals while enjoying a residence of three to six months. The program includes a stipend, research support, and housing, fostering intellectual exchange in a world-renowned setting. Applications are welcome from qualified individuals globally, enhancing the exploration of ancient Mediterranean art.
Humanities & Social Science Art History

The Shell Science Teaching Award

National Science Teachers Association
Association/Society
Philadelphia County, Pennsylvania
US $10,000
The Shell Science Teaching Award, a collaboration between Shell USA, Inc. and the National Science Teaching Association (NSTA), honors an exceptional K-12 classroom teacher who significantly influences students, their school, and the community through outstanding science education. The award offers a $10,000 prize and includes an expense-paid trip to the NSTA National Conference on Science Education for the recipient and finalists, along with certificates for semifinalists.
Science Teacher Development & Training

Fellowships for Faculty- Career Enhancement Fellowship

Institute for Citizens & Scholars
Private
United States
Up to US $35,000
The Career Enhancement Fellowship, offered by Citizens & Scholars, supports junior faculty from diverse backgrounds in the humanities and humanistic social sciences. With stipends up to $35,000, funding for research, and travel support, this program nurtures academic diversity and enhances campus perspectives. Since 2001, over 400 fellows have advanced their careers while fostering a rich academic community. The fellowship promotes innovative scholarship and leadership roles, contributing to a more inclusive academic environment.
Humanities & Social Science Art & Culture Religion & Spirituality

Newington Community Fund (Previously Newington Greater Together Community Fund Grant)

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
Unspecified amount
The Hartford Foundation for Public Giving has launched the $100,000 Greater Together Community Fund Grant for Newington. This initiative aims to empower local communities by fostering ownership of their needs, promoting inclusive civic engagement, and strengthening the Foundation's presence in towns. Eligible applicants include any 501(c)(3) nonprofit organization serving West Hartford residents, regardless of their base. The GTCF Committee will facilitate a process to identify community needs and ensure impactful grantmaking.
Community Services Civic Engagement & Education

Robert W. Lukens Scholarship

The Columbus Foundation
Private
Franklin County, Ohio
US $2,500

The Columbus Foundation

In 1943, during the darkness of World War II, a group of passionate citizens, led by Columbus businessman Harrison M. Sayre, envisioned a way to improve the well-being of the community and the quality of life in central Ohio. With little more than this sound idea and faith, The Columbus Foundation was established.

Our Mission

To assist donors and others in strengthening and improving our community for the benefit of all its residents.

Robert W. Lukens Scholarship

The scholarship honors the namesake, who was a 1940 engineering graduate from The Ohio State University and inspired generations of family engineers. The purpose is to helps students pay for college expenses.

Education - Higher Education Engineering

David E. Hyre Memorial Scholarship Fund

Community Foundation of Randolph County
Private
Indiana
Unspecified amount

Community Foundation of Randolph County

Our mission is to bring people and resources together to strengthen the quality of life, both now and in the future, for the residents of Randolph County.

The Community Foundation’s work falls into three major categories: grant-making, donor service, and community convening. Our most visible activities are the grants and scholarships we award each year. Most of these awards come from income earned from permanently endowed funds. Scholarships and other grants come from funds that donors have established for specific purposes.

David E. Hyre Memorial Scholarship Fund

The David E. Hyre Memorial Scholarship was created by Mr. Hyre’s daughters in his memory. David Hyre, born in 1943, graduated Winchester High School in 1961. He also attended Purdue University (Mechanical Engineering Bachelors), University of Michigan (Mechanical Engineering Masters), and Michigan State University (M.B.A.). He was a part of the Chrysler Institute of Engineering (CIE Program). He worked as an engineer and a manager during his 35 years at Chrysler until he retired in 2001. David was very active with Habitat for Humanity and ushered at the Maddie Kelly Center for the Arts in Niceville, FL. He was also an election poll volunteer and Special Deputy for Okaloosa County, FL. His favorite hobby was collecting watches; he was a member of the National Association of Watch and Clock Collectors and participated in shows across the country.

This is a four-year scholarship for a student graduating from a Randolph County high school attending Purdue University studying engineering.

Education - Higher Education Engineering

The Greater Mount Hope Community Fund

Beckley Area Foundation
Private
Fayette County, West Virginia
Up to US $41,000
The Greater Mount Hope Community Fund, initiated in 2007 by dedicated citizens, aims to revitalize the historic Mt. Hope area through community-driven programs and fundraising. Managed by the Beckley Area Foundation, this endowment supports local initiatives that enhance the quality of life for residents. With a commitment to sustainable giving, the fund has engaged in various successful activities, including selling local calendars and organizing fundraising campaigns, ensuring a lasting impact on the community.
Community Services Economic Services & Development

AF: Grants - $5,001 and Above - Community Development, Religion & Other

Ashtabula Foundation
Private
Ashtabula County, Ohio
More than US $5,001
The Ashtabula Foundation offers grants of $5,001 and above to support community development, religious initiatives, and other charitable efforts in Ashtabula County. Eligible organizations must possess a 501(C)(3) status and serve the local community. This foundation prioritizes human services but considers various requests based on available funding and community impact. Applications are limited to one per organization annually, ensuring focused support for each initiative.
Community Development & Revitalization Religion & Spirituality Community Services

Suffield Community Fund at Greater Hartford Gives

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $500 - US $7,500
The Suffield Greater Together Community Fund Grant, established by the Hartford Foundation for Public Giving, offers financial support to enhance community ownership and engagement in Suffield. With grants ranging from $250 to $7,500, the fund encourages initiatives that benefit local residents and foster civic participation. Eligible organizations must be 501(c)(3) exempt or use a fiscal sponsor, ensuring that funding directly supports community-driven projects.
Community Services Civic Engagement & Education

Ackerman Foundation Grant (Columbia County, NY)

Ackerman Foundation Inc.
Private
Columbia County, New York
Up to US $2,500
The Ackerman Foundation Grant supports non-profit organizations in Columbia County, NY, aiming to enhance the quality of life for people and animals. Grants of up to $2,500 are awarded based on merit, alignment with mission, and community impact. Applicants must be tax-exempt under 501(c)3 or utilize a Fiscal Agent. The foundation emphasizes transparency and competition in its granting process, ensuring that those who serve their communities effectively receive assistance.
Community Services Animal Welfare - General Human & Social Services

CFOV: Stealey Community Fund

Community Foundation for the Ohio Valley
Private
Tyler County, West Virginia
Unspecified amount
The CFOV: Stealey Community Fund, overseen by the Community Foundation for the Ohio Valley, supports educational, religious, and community organizations that benefit Middlebourne, WV residents. Established by Ruth Stealey Green in memory of her family, the fund prioritizes projects enhancing local quality of life, such as library and recreational services. Eligible organizations must be 501(c)(3) tax-exempt or similarly exempt government entities. Grant applications are welcomed from those with impactful project ideas.
Education Religion & Spirituality Community Services

Community One Stop for Growth

Commonwealth of Massachusetts
State/Local Government
Massachusetts
Unspecified amount

The One Stop is a single application portal and collaborative review process that allows applicants to access a series of grant programs that support community economic development. The Executive Office of Economic Development (EOED) partners with the Executive Office of Housing and Livable Communities (EOHLC) and Massachusetts Development Finance Agency (MassDevelopment), to make targeted grant investments based on a Development Continuum. 

Community Services Economic Services & Development

Faerie L. Angle Memorial Scholarship Fund

The Foundation for Enhancing Communities
Private
United States
Unspecified amount
The Faerie L. Angle Memorial Scholarship Fund, established by the Foundation for Enhancing Communities, provides scholarships to aspiring lawyers from Franklin County, PA. Eligible candidates must have been accepted into a three-year J.D. program, maintain a minimum GPA of 3.0 to 3.5, and demonstrate financial need. This initiative aims to support local talent in pursuing legal education and fostering community engagement through the legal profession.
Law Education - Higher Education

River Falls Community Foundation Big Idea Grants

St. Croix Valley Foundation
Private
Pierce County, Wisconsin, St. Croix County, Wisconsin
Up to US $25,000
The River Falls Community Foundation Big Idea Grants aim to enhance the quality of life in River Falls, Wisconsin. With grants up to $25,000, this program seeks innovative projects that support community pride, assist underserved citizens, and address environmental concerns. Open to qualified non-profit organizations, the initiative is driven by a volunteer board dedicated to ensuring that donations effectively improve the community's future well-being. Applications are accepted every other year.
Community Services Environment

ACF: Emergency Helping Hands Grant

Anaheim Community Foundation
Private
Orange County, California
US $500 - US $2,500
The ACF Emergency Helping Hands Grant, offered by the Anaheim Community Foundation, provides support to non-profit organizations facing one-time challenges. Established in 1984, the Foundation fosters community enrichment through various programs. Special consideration is given to organizations serving youth and at-risk populations, addressing critical needs such as poverty and mental health. Applications are accepted year-round, with a focus on community resilience and volunteerism.
Community Services Youth Services

Pangburn Foundation Grant

Pangburn Foundation
Private
Texas
Up to US $150,000
The Pangburn Foundation Grant supports charitable, religious, educational, or scientific organizations in Texas. This private foundation, administered by JPMorgan, funds only nonprofit organizations recognized under section 501(c)3 of the IRS tax code. Individuals are not eligible to apply for this grant. For more information about the application process, please visit the foundation's finder link provided by JPMorgan.
Religion & Spirituality Science Education

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.