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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$9.00B

Total funding

$6K

Median grant

32,000+ grants
$9.00B total
$6K median

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32,423 Results based on applied filters

Streicker Fund for Student Research

Yale University
Private
Asia, Australia and New Zealand +26 more
US $1,600 - US $4,000
The Streicker Fund for Student Research at Yale University offers financial support for academic projects requiring international travel, primarily aimed at students conducting research under faculty supervision. These projects may include field research and interviews, and must occur during school breaks. The fund targets various destinations based on expense levels, ensuring accessibility for a broad range of students. This initiative emphasizes the importance of educational travel while maintaining academic commitments.
Law Academic Success & Enrichment

Robert A. & Geneva K. Deveney Engineering Scholarship

Armstrong County Community Foundation (The Community Foundation Serving the Heart of Western Pennsylvania)
Private
United States
Unspecified amount

Armstrong County Community Foundation

The Armstrong County Community Foundation, a public nonprofit corporation,

  • Gives grants, scholarships, and organizational support to address the needs of our community.
  • Builds a permanent endowment to help our donors create a legacy through this endowment.
  • Promotes informed philanthropy to increase and sustain charitable resources for the region.
  • Provides leadership and builds partnerships to identify and solve community issues.

Robert A. & Geneva K. Deveney Engineering Scholarship

This scholarship was established to provide funds for graduating seniors from Armstrong County high schools planning to study engineering.

Scholarship Details

  • Available to High School Seniors
  • Nonrenewable

All ACCF Scholarships are merit based.

Engineering Education - Higher Education

Micro Grants Program

The Community Foundation of Jackson Hole
Private
Teton County, Idaho
Up to US $2,000
The Micro Grants Program, offered by The Community Foundation of Jackson Hole, provides timely funding to 501(c)(3) nonprofits and government entities serving Teton County, Wyoming. Applications are accepted from the 1st to the 15th of each month, allowing for project proposals that address immediate community needs. These grants aim to support impactful initiatives, while funds cannot be used for operating expenses or projects already completed. For further details, contact grants@cfjacksonhole.org.
Community Services Environment

ABE Opportunity Grants

American Bar Endowment
Private
American Samoa, Guam +4 more
Up to US $25,000
The American Bar Endowment's Opportunity Grant Program provides funding for innovative, boots-on-the-ground initiatives that address urgent legal needs of the public. This grant focuses on increasing access to justice for underserved populations, improving the justice system, and enhancing public understanding of legal rights. Eligible applicants include public charities and organizations directly impacting local communities, with a strong emphasis on projects that leverage technology and address immediate legal challenges.
Law Legal Services

Abandoned Mine Land Economic Revitalization Program

Virginia Department of Energy
State/Local Government
Virginia
Unspecified amount

About Virginia Energy

Virginia Energy is the state agency charged with advancing Virginia's energy, mining, and mineral policies and initiatives. Our mission is to lead the Commonwealth to a safe, reliable and responsible energy future by:

  • Providing for safe and environmentally sound stewardship of Virginia's mineral and energy resources;
  • Encouraging economic development through the sound stewardship of Virginia's energy, mineral, land and water resources; and
  • Successfully pursuing federal funding and implement the Virginia Energy Plan to ensure the Commonwealth has abundant, reliable, affordable and increasingly clean energy.

Abandoned Mine Land Economic Revitalization Program

Virginia Energy is one of nine states and tribal programs chosen by Congress to receive funding in Fiscal Year 2025 to develop and repurpose Abandoned Mine Lands with economic and community development end uses. The 2025 Abandoned Mine Land Economic Revitalization Program (AMLER) funding is made available as a direct payment by the federal Office of Surface Mining Reclamation and Enforcement (OSMRE), in accordance with the Full Year Continuing Appropriations Act, 2025 (Public Law No. 119-4). Virginia has received an average of $10.48 million per year since 2017. Virginia's payment in FY2025 is $11 million.

Projects must follow eligibility and other guidelines set forth in OSMRE's AMLER Guidance document and adhere to Virginia Energy's terms and conditions. Applicants are encouraged to submit projects with the greatest potential to achieve the economic and community development goals of the AMLER Program.

Energy Renewable/Sustainable Energy Energy Efficiency & Conservation +2 more

Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $190,000 - US $500,000
The R21 Clinical Trial Not Allowed funding opportunity invites innovative research to develop and enhance research models and biological materials vital for studying human health and diseases. It emphasizes the need for new approach methodologies (NAMs) to improve the identification of confounding factors in biomedical research. Projects should have broad applicability across multiple NIH Institutes, focusing on various body systems and disease categories, ensuring relevance to a wide range of health issues.
Biology Health & Medicine Emerging Technology Development

The Reuter Scholarship Fund

Community Foundation for Palm Beach and Martin Counties
Private
United States
Unspecified amount

Scholarships support aspiring college students who hold the promise of tomorrow’s progress.

Together, our competitive grants and scholarships help our region rise thanks to the vision and generosity of our donors.

The Reuter Scholarship Fund

  • Interested in pursuing a career in engineering, science or technology
  • Based on good moral character and student’s overall performance as to academic ability and standing, extracurricular activities, success in dealing with life’s challenges in individual circumstances and financial need
Engineering STEM / STEAM Education

Thomas D. Buckley Trust Grant

Thomas D. Buckley Trust
Corporate
Cheyenne County, Nebraska, Deuel County, Nebraska +2 more
Unspecified amount
The Thomas D. Buckley Trust Grant, established by Thomas D. Buckley, supports nonprofit organizations focusing on education, religion, and community programs primarily in the Western Panhandle of Nebraska and Northeast Colorado. Following Buckley's passing in 1979, the Trust was formed and has since provided grants to tax-exempt organizations that demonstrate sound financial management and adhere to eligibility requirements, with monthly reviews of grant requests.
Community Services Education Religion & Spirituality

Sylvia Shugrue Award for Elementary School Teachers

National Science Teachers Association
Association/Society
California
Up to US $1,500
The Sylvia Shugrue Award for Elementary School Teachers recognizes outstanding educators who create interdisciplinary, inquiry-based lesson plans. This prestigious award, funded by the National Science Teachers Association, includes a $1,000 grant and additional funding for attending the NSTA National Conference on Science Education. Eligible applicants must be full-time elementary teachers with a minimum of five years of experience and must be NSTA members in good standing. This initiative aims to enhance science education in elementary schools.
Science Teacher Development & Training

Eda Camphausen Law Scholarship

Erie Community Foundation
Private
Middlesex County, Massachusetts
Unspecified amount
The Eda Camphausen Law Scholarship, awarded by the Erie Community Foundation, supports first-year law students at Harvard University who are residents of Erie County. Applicants must have achieved the highest LSAT score for their admission year. In 2023, the foundation provided over $800,000 in scholarships to more than 500 deserving students, emphasizing its commitment to enhancing educational opportunities in the community.
Law Academic Scholarship Programs

Bank of America Boston Marathon Official Charity Program

Boston Athletic Assoc
Private
Middlesex County, Massachusetts, Norfolk County, Massachusetts +1 more
Unspecified amount in in-kind support
The Bank of America Boston Marathon Official Charity Program supports non-profit organizations by providing invitational entries to the marathon. These organizations recruit athletes who pledge to raise funds for their causes. The B.A.A. prioritizes groups focused on building healthy communities, particularly those benefiting the local areas along the marathon route. Eligibility requires organizations to be registered 501(c)(3) and not religious or political. The program emphasizes diversity, inclusion, and sustainability.
Community Services Wellness & Healthy Living

Creative Community Solutions Grant Program

Bush Foundation
Private
North Dakota
Up to US $300,000
The Creative Community Solutions Grant Program, launched by the Bush Foundation in partnership with Strengthen ND, seeks innovative solutions to community challenges in North Dakota. Grants up to $300,000 are available for projects that develop, test, and spread impactful ideas. This initiative empowers diverse local voices through a Grantmaking Committee, ensuring funds are allocated to initiatives that enhance community well-being. Importantly, it focuses on collaborative efforts and does not provide operational support for organizations.
Community Culture & Heritage Community Services

Hugh M. Nelson Engineering Scholarship

Erie Community Foundation
Private
Erie County, Pennsylvania
Unspecified amount
The Hugh M. Nelson Engineering Scholarship, funded by the Erie Community Foundation, supports Erie County residents who are sophomores or juniors enrolled in an ABET-accredited BS Engineering Program at Penn State Behrend or Gannon University. Over $800,000 was awarded in 2023 to help deserving students pursue their educational goals. Selection is based on academic standing, faculty recommendations, involvement in college activities, and financial need.
Academic Scholarship Programs Engineering

Build OC Fund

Samueli Foundation
Private
Orange County, California
Up to US $1,000,000
The Build OC Fund, under the Samueli Foundation, aims to enhance community well-being in Orange County, California, by funding capital projects for nonprofit organizations. Grants of up to $1,000,000 support facility acquisition, construction, renovation, or equipment purchases, helping organizations deliver essential services. Eligible applicants must demonstrate site control and a commitment to the community, with a focus on realistic projects that align with the foundation's mission. Prioritization is given to projects nearing completion.
Community Services Historic Preservation Nonprofit Growth & Development

Deihl Humanities Grants

Greater Manhattan Community Foundation
Private
Riley County, Kansas
More than US $10,000
The Deihl Humanities Grants, established by the Greater Manhattan Community Foundation, aim to support community and public arts or humanities projects that enhance the quality of life in Manhattan and Riley County, Kansas. With a focus on proposals exceeding $10,000, these grants encourage initiatives that bring humanities to life through public programming, fostering community engagement and connections among individuals.
Humanities & Social Science Public / Community Art

Constitution Day Grants - Mini Grants

Louisiana Endowment for the Humanities
Private
Louisiana
Up to US $1,400

Louisiana Endowment for the Humanities 

The Louisiana Endowment for the Humanities acts as a steward and supporter of Louisiana’s diverse and vibrant culture and history.

To that end, we are dedicated to ensuring access to the humanities, offering and broadening pathways for a lifetime of learning for people of every generation and from every walk of life. We champion the humanities to enrich the lives of all Louisianans in all 64 parishes. 

Our Mission: The Louisiana Endowment for the Humanities’ mission is to partner with communities, institutions, and individuals to explore Louisiana’s past, reflect on our present, and imagine our future.

Constitution Day Grants

Mini grants to institutions supporting existing or developing Constitution Day programming. 

Humanities & Social Science Community Culture & Heritage

Palmer Community Foundation Grant Program

The Alaska Community Foundation
Private
Matanuska-Susitna Borough, Alaska
US $1,000 - US $5,000
The Palmer Community Foundation Grant Program, an affiliate of The Alaska Community Foundation, aims to enhance the quality of life for Palmer area residents by supporting diverse community projects. Funded by a growing endowment, the program prioritizes health, education, outdoor activities, arts, and community development. Eligible applicants include tax-exempt organizations and projects must be completed within a year. Preference is given to new applicants with measurable outcomes and broad community impact.
Community Services Environment

Community Planning Technical Assistance Program (C-TAP)

Pennsylvania Department of Community and Economic Development
State/Local Government
Pennsylvania
Unspecified amount

Community Planning Technical Assistance Program (C-TAP)

Overview The Community Planning Technical Assistance Program (C-TAP) helps local and county governments, along with municipal partner organizations, plan, prepare, and implement strategies that support long-term growth and development. 

The Community Planning Technical Assistance Program (C-TAP) helps local and county governments, along with municipal partner organizations, plan, prepare, and implement strategies that support long-term growth and development. Whether updating ordinances, scoping a larger study, or moving a completed plan into action, eligible applicants receive hands-on, tailored support from experienced planners. C-TAP helps communities move confidently from idea to implementation, with up to 400 hours of technical assistance available per project.

Funding

This program does not provide funding. C-TAP helps communities move confidently from idea to implementation, with up to 400 hours of technical assistance available per project.

Urban Planning Emerging Technology Development

C. Warren Barry Perpetual Foundation Grant

Barry C Warren Fdn Ta
Private
Lake County, Florida
US $1,000 - US $2,500
The C. Warren Barry Perpetual Foundation Grant supports charitable, educational, and religious causes, primarily within Lake County, Florida. Established in the late 1970s by Mr. Barry, the foundation exclusively funds organizations recognized under IRS Section 501(c)(3). Types of support include program funding, general operating expenses, and scholarships. However, it does not provide grants for capital improvements, ensuring that resources are directed towards immediate community needs.
Education Community Services Religion & Spirituality

Chris Marshall Endowed Presidential Scholarship

William Wayne Justice Center for Public Interest Law
Private
Texas
US $3,000 - US $6,000
The Chris Marshall Endowed Presidential Scholarship, established by the William Wayne Justice Center for Public Interest Law, supports outstanding third-year law students committed to public service in Texas. Eligible applicants must have a GPA of 3.44 or higher and demonstrate a strong intent to work in nonprofit, government, or legislative positions post-graduation. This scholarship not only aids students financially but also fosters a commitment to increasing access to justice through public interest lawyering.
Law Legal Services

Bob Kelly Scholarship

The San Diego Foundation
Private
San Diego County, California
Up to US $10,500

Bob Kelly Scholarship

During his 20 years as President and CEO of San Diego Foundation (SDF), Bob Kelly built an enduring legacy that has seen SDF become the regional leader for information about charitable giving and a strong voice for civic engagement. Among a number of significant achievements as President and CEO, Bob was instrumental in building the Community Scholarship Program which is now the largest scholarship provider in San Diego County outside of the university system.

When establishing his own scholarship, Bob wanted to recognize the important role that both San Diego City College and UC San Diego play in the education of so many San Diegans. His hope is to provide a unique scholarship opportunity to those students who may not have been the top of their class, but have since taken advantage of their own “second chance” and are on the path to success.

This scholarship may be used for tuition, books, fees, room & board, and other educational expenses.

The scholarship may be renewable (depending upon available funds) for up to two years of undergraduate coursework at UC San Diego provided the student maintains a minimum GPA of 2.5 on a 4.0 scale, good citizenship, and continues to have financial need.

  • Average number of awards: 2
  • Average amount: $3,500
Education - Higher Education Community Services

County-Wide Basic Needs Grants

The Community Foundation of Marquette County
Private
Marquette County, Michigan
Up to US $10,000

County-Wide Basic Needs Grants

The Basic Needs Grant Cycle provides funding to organizations addressing urgent and foundational needs within local communities. This grant is designed to strengthen the safety net for individuals and families experiencing hardship by supporting programs that deliver food, clothing, essential items, and safe shelter. 

Applicants may request up to $10,000 in funding. Partial awards may be granted based on project need, available funds, and proposal strength. 

Funding Priorities 

Priority will be given to projects and programs that:

Address Immediate or Chronic Food Insecurity: Including food pantries, meal programs, weekend backpack programs, or other efforts ensuring access to nutritious food. 

Provide Essential Clothing: Programs supplying seasonal clothing, winter gear, or everyday clothing in emergency situations for individuals and families. 

Meet Critical Essential Needs: Initiatives providing hygiene products, household essentials, baby items, transportation assistance, or other core necessities. 

Support Access to Safe Shelter: Emergency shelter, transitional housing, homelessness prevention, and programs improving safety or stability for people without housing. 

Use of Funds 

Allowable costs may include, but not limited to: 

  • Food purchases or meal program costs 
  • Clothing purchases, supplies, or storage needs 
  • Hygiene kits, diapers, and essential household items 
  • Emergency shelter operations or upgrades 
  • Outreach and distribution costs 
  • Personnel time directly tied to program implementation 
Basic Human Needs Community Services

Donald W. F. Ching Memorial Scholarship Fund

Hawai'i Community Foundation
Private
United States
Unspecified amount
The Donald W. F. Ching Memorial Scholarship Fund honors Donald Ching, a dedicated Hawaiian Airlines employee. This scholarship is aimed at students in Hawaii who demonstrate financial need and maintain a minimum GPA of 2.0. Preference is given to first-generation college students and those with a GPA of 3.0 or higher. Applicants must be pursuing a degree in Aviation at an accredited institution in the U.S. The fund supports educational advancement for future aviation professionals.
Academic Scholarship Programs Aviation

NIAID Physician-Scientist Pathway to Independence Award (K99/R00 Independent Clinical Trial Not Allowed) (345300)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $249,000
The NIAID Physician-Scientist Pathway to Independence Award (K99/R00) aims to support new independent physician-scientists by facilitating their transition from postdoctoral research to tenure-track faculty positions. This program provides essential research funding to help awardees establish their careers in biomedical research, addressing the national shortage of physician-scientists. Applicants must propose research that does not lead an independent clinical trial, but may include mentorship in clinical trials.
Medical Education & Professional Training Science

Farmington Greater Together Community Fund Grant

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $500 - US $5,000
The Farmington Greater Together Community Fund, established by the Hartford Foundation for Public Giving, offers up to $7,500 for projects that promote civic engagement and community ownership. This fund supports organizations classified as 501(c)(3) or those using a fiscal agent. Eligible projects must benefit all residents without discrimination and may include broader community initiatives by religious organizations. A final report is required upon project completion.
Community Services Civic Engagement & Education

Jeffrey A. Trail Memorial Fund

Dekalb County Community Foundation
Private
United States
Unspecified amount

Scholarship amounts vary depending on the scholarship applied for. Applicants are encouraged to apply for as many awards as they are eligible to increase the likelihood of receiving one or more awards.

Scholarships can be used for cost of attendance, direct education expenses, including tuition, books, and/or other school-related fees.

If you receive an award, be sure to complete your scholarship acceptance form (online portal). Scholarship awards are paid directly to the academic institution by the end of August.

Jeffrey A. Trail Memorial Fund

Created in memory of Lt. Jeffrey A. Trail in honor of his military service and accomplishments, this Fund offers scholarships to DeKalb County residents who are graduating seniors and continuing their education immediately following high school graduation at an accredited two-year or four-year college or university studying aviation technology (a.k.a. professional flight or similar degree) for pilot training only; or at an independent certified flight training program working toward flight/pilot certifications.

Education - Higher Education Aviation

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.