Best Myrtle Beach Grants for Nonprofits in South Carolina

The Myelodysplastic Syndromes (MDS) Research Fund Grant, established by the Vera and Joseph Dresner Foundation, aims to enhance research and treatment of MDS and related blood disorders. This fund supports innovative projects addressing etiology, biology, genetics, prognosis, treatment, symptom management, and quality of life. It offers up to $125,000 for Early Career Awards and $250,000 for Established Investigator Awards, facilitating significant advancements in the field.

The SC Ministry Foundation provides annual grants aimed at supporting nonprofit organizations aligned with the mission of the Sisters of Charity of Cincinnati. These grants can be used for core programs, planning, and program expansion. Eligible organizations must demonstrate financial sustainability and avoid duplication of services. The application process starts with a pre-application survey, and funding decisions are typically made by June 30. Priority is given to projects in education, healthcare, and social services.

Stealth Biotherapeutics offers grants and sponsorships aimed at enhancing healthcare education for providers and patient communities. These funding opportunities focus on innovative programs that address rare genetic disorders, neurodegenerative conditions, and ophthalmic disorders. To apply, requests must be submitted 60 days prior to the funding start date, ensuring alignment with the therapeutic interests of the organization while providing valuable insights for healthcare professionals.

Stealth Biotherapeutics is dedicated to supporting innovative programs that enhance disease awareness and therapeutic management. Their charitable contributions focus on accredited institutions, promoting educational initiatives for health care providers and patient communities. Funding is prioritized for unique and cost-effective projects that align with their therapeutic interests, including rare genetic disorders, neurodegenerative diseases, and ophthalmic conditions. By fostering community awareness, they aim to make a significant impact in the healthcare landscape.

Who We Are

The Unitarian Universalist Funding Program (UUFP) is a denominational grantmaking program of the Unitarian Universalist Association. Inspired by the richness and diversity of our liberal religious tradition, the mission of the UUFP is to promote the influence of Unitarian Universalist principles through grantmaking.

With funds generously provided by the Unitarian Universalist Veatch Program at Shelter Rock, the UUFP awards grants to Unitarian Universalist (UU) and non-UU projects and organizations. Grants are made that:

• Support the work of social justice.
• Strengthen Unitarian Universalist institutions.
• Transform gratitude for being into generosity of living.

Get Out The Vote - 2026

The Fund for UU Social Responsibility has increased funding for grants to UU congregations and organizations working to Get Out The Vote in 2026. Grants of up to $1,000 will be made on a rolling basis until funds are depleted.  

Please note that funds must go to a UU congregation or organization for the work by UUs of the organization. The funds may not be passed through to another organization. Collaboration and partnerships are encouraged.

UU congregations and organizations frequently support the democratic process in an election cycle in a non-partisan* manner by participating in voter registration drives, organizing to stop voter suppression, providing non-partisan educational materials or forums for voters, or by volunteering to help registered voters get to the polls on election day.

The Officers’ Research Grants on Reducing Inequality support studies aimed at understanding and addressing inequalities affecting youth ages 5-25 in the U.S. This initiative funds descriptive, intervention, and measurement development studies focused on academic, social, behavioral, and economic outcomes. The William T. Grant Foundation encourages research that identifies specific inequalities and explores effective programs or policies to mitigate these disparities while addressing systemic issues such as racism and structural inequality.

The McKnight Endowment Fund for Neuroscience offers Scholar Awards to early-career neuroscientists focusing on learning and memory disorders. The awards provide up to $225,000 over three years, emphasizing research that could lead to significant clinical advancements. Eligible candidates must work as independent investigators at U.S. non-profit institutions, hold an Assistant Professor position for less than four years, and demonstrate their research program's potential. The program aims to foster innovative solutions in neuroscience.

The JA Community Foundation focuses on funding solutions that address the needs of the Japanese American and broader Asian American communities. They prioritize programs that enhance senior health, promote history, arts, culture, and support youth. Eligible applicants must be registered 501c3 organizations and can apply from all 50 states. However, organizations with open grants cannot submit new applications until their current grants are closed.

Grants

Through our grantmaking, we support nonprofits that serve South Carolina at local, regional and state levels to address root causes of poverty while honoring the dignity of every South Carolinian.

Starting in 2026, our grants focus primarily on systems change in the areas of

• economic mobility,
• housing security and
• health care (with health care systems change grants by invitation only).

By focusing our efforts and going deeper on these three issues, we aim to have an even greater impact on the nonprofits and communities we serve.

Systems Change Grants

Systems Change Grants fund organizations and coalitions that are working to change the policies, power structures and mindsets that cause and reinforce poverty in South Carolina. These grants specifically fund systems change that supports economic mobility and housing security.

Through these grants, we aim to generate a larger impact through more intentional funding, highly focused work and alignment across our Foundation’s activities.

What Systems Change Grants Support

• Organizations that are actively working on systems change that impacts people experiencing poverty and addresses economic mobility or housing security. To see how the Foundation defines these terms, visit our Strategic Plan webpage.
• Organizations that are seeking to change systems at the local, regional or state level. Systems Change Grants provide up to $75,000 annually for local or regional work.
  • State-level grants have a $100,000 maximum each year. 
• Organizations addressing systems change in at least one of the following ways:
  • Participating in advocacy and lobbying
    • Focus on changing policies, practices, processes, rules or laws
    • Impacting resource flows (i.e., reallocated and/or new funding streams)
    • Holding systems accountable to their intended purpose through the above as well as through litigation
  • Addressing unequal power
    • Focus on changing the distribution and dynamics of privilege, relationships and tradition
    • Organizing and building connections and coalitions that center community voices and perspectives
    • Civic engagement
  • Affirming the dignity of people experiencing poverty
    • Focus on changing the narrative around poverty
    • Focus on changing attitudes, mindsets, values, belief systems, norms, mental models and paradigms
  • Implementing big impact, scalable, or innovative solutions
    • Focus on changing results, especially for groups experiencing inequitable outcomes as a result of historic and current marginalization

All grants are for one year, with the possibility of renewal up to three years based on meeting reporting requirements and the availability of funding.

The Delta Dental of Missouri Grant Program aims to improve oral health in Missouri by funding initiatives that reduce oral disease, enhance access to quality dental care, and raise awareness, particularly among underserved populations. Grants range from over $5,000 to $100,000 and are awarded for one year, focusing on projects that increase access to care and demonstrate matching funds from other sources.

Delta Dental of Missouri's Community Donation Program aims to enhance community health through charitable contributions, focusing on organizations that serve Missouri and South Carolina. Preference is given to those with an oral health component. Eligible organizations must be 501(c)(3) registered, address the needs of at-risk populations, and be represented by an authorized member for support requests. This initiative underlines Delta Dental's commitment to community well-being and support.

Charlie's Heart Foundation Annual Grant Program supports small nonprofits focusing on mental well-being for families in underserved communities. Grants between $5,000-$30,000 are available, prioritizing organizations based in North Carolina. Eligible applicants must be 501(c)(3) tax-exempt and demonstrate alignment with the Foundation's mission, organizational need, and program sustainability. The Foundation does not fund individuals, private foundations, or religious organizations, ensuring a strong focus on impactful community programs.

Nikon USA is dedicated to supporting innovative initiatives that align with its marketing strategies and community impact. They seek sponsorship proposals that demonstrate unique ideas, enhancing brand engagement and consumer reach. However, applicants must be over 18 and submit requests at least six months prior to their program. Nikon prioritizes USA-based entities and cannot support individual projects or certain causes. For more details, please submit your request through their designated online form.

The True Inspiration Awards, established by Chick-fil-A in 2015, recognizes nonprofit organizations that significantly impact their communities. In 2025, the program will distribute $6 million in grants, ranging from $30,000 to $350,000, to sixteen selected organizations. Categories include Caring for People, Caring through Food, Community, and Caring for our Planet, with a focus on educational initiatives, food security, housing services, and environmental stewardship, honoring the legacy of founder S. Truett Cathy.

The Covenant Foundation's Signature & Ignition Grants celebrate excellence in Jewish education by funding innovative projects that enhance educational practices. The Foundation supports diverse institutions across North America, inviting applications for creative programs that can adapt and disseminate effective practices. While Signature Grants may reach up to $150,000 over three years, Ignition Grants focus on untested ideas with funding up to $20,000 for one year. One application per cycle is permitted.

The Wadsworth Golf Charities Foundation Program Grants aim to promote self-discipline, culture, and etiquette through golf, enriching lives and fostering charity. The foundation focuses on providing grants exclusively to 501(c)3 organizations, ensuring that only one application per organization is accepted each year. By encouraging youth and individuals of all ages to engage with the game, the foundation aspires to instill valuable life lessons and a sense of community, making golf a powerful teacher.

The Barbara McDowell and Gerald S. Hartman Foundation Grant supports social justice litigation in the U.S. by providing funding to organizations involved in systemic legal cases. Since 2009, the foundation has awarded over $1.4 million to 49 organizations, enhancing the lives of disadvantaged groups through impactful legal advocacy. The foundation prioritizes cases that align with its focus areas, including children's rights, discrimination, and homelessness, ensuring comprehensive support for societal improvement.

The Life Comes From It Grant, funded by the Tides Foundation, supports grassroots initiatives focused on restorative, transformative, and indigenous justice. It prioritizes projects led by communities of color, emphasizing alternatives to incarceration and community-led solutions. Applicants must be 501c3 organizations based in the United States. This grant fosters a collaborative approach to healing and justice, aiming to shift power dynamics and promote inclusive practices across generations.

The Humanity United Grant focuses on addressing human exploitation and violent conflict through a strategic approach. It emphasizes support for registered charities and initiatives globally, particularly in regions like Asia-Pacific and South Sudan. The grant fosters collaboration among partners to promote human dignity, racial justice, and peacebuilding. Interested organizations are encouraged to align their proposals with the outlined themes and engage with the funder for potential support.

The Native American Agriculture Fund (NAAF) offers grants to support Native farmers and ranchers through business assistance, agricultural education, technical support, and advocacy services. Established from the Keepseagle v. Vilsack settlement, NAAF is committed to providing essential resources to eligible organizations, including 501(c)(3) nonprofits, educational institutions, and tribal governments. Special focuses include inflation assistance and market access, ensuring a holistic approach to agricultural support.

The Security and Preparedness (SAP) Program, supported by the National Science Foundation, promotes fundamental research addressing global and national security issues. It emphasizes intellectual merit and broader impacts, encouraging projects that are methodologically sound and empirically driven. Research areas include international relations, political violence, and peace science, among others. The program also fosters undergraduate research experiences and methodological innovations, while strictly avoiding applied research.

The Civic Engagement Microgrant Grant Program, funded by Research!America, aims to enhance public engagement skills among early-career scientists. By providing financial support for innovative projects, this initiative encourages collaborations across various STEM disciplines. Grantees will develop essential skills in communication and policy-making to strengthen community ties and promote science as a national priority. This program addresses the critical need for scientists to connect with local communities and policymakers to ensure the relevance and impact of scientific research.

The Rachael Ray No-Kill Excellence Grants, funded by the Rachael Ray Foundation, support Best Friends Network partners in maintaining a 90% Save Rate for animals. These grants encourage innovative projects that enhance community partnerships and mentorships, helping organizations achieve sustainable lifesaving outcomes. Eligible organizations can apply for grants up to $60,000, with a focus on scalable programs that benefit animals and promote no-kill initiatives across the United States.

The Brave Heart Foundation Grant aims to uplift underserved populations, focusing on children and families through education, health, and community action. With a commitment to funding impactful programs in Indiana, the Foundation prioritizes organizations that demonstrate clear community benefits. Larger funding requests are accepted from previously funded agencies, ensuring continuity and accountability. This grant serves as a vital resource for initiatives that enhance the well-being of those in need, fostering positive change within local communities.

The Monsignor Leo Adamiak Trust Grant provides financial assistance to Ukrainian Catholic parishes in the U.S. and Ukraine, aiming to support their educational and operational needs. Eligible organizations must demonstrate a commitment to community service with a history of at least three years. The trust favors projects with measurable impacts and sustainable outcomes, while not supporting general operating costs or for-profit entities. Interested parishes should contact for application materials, as online applications are not accepted.

The NALAC Fund for the Arts offers organization grants focused on supporting Latinx artists and arts organizations in the U.S. and Puerto Rico. This funding initiative has invested over $6 million in the arts community, nurturing creativity and social change. Eligible applicants include organizations with a mission centered on Latinx arts. The program aims to enhance artistic excellence and community engagement, making it a vital resource for cultural production and social justice efforts.

The Science of Science: Discovery, Communication, and Impact (SoS:DCI) program fosters research that enhances the public value of scientific endeavors. It invites proposals that explore mechanisms of scientific discovery, improve understanding of communication outcomes, and assess societal benefits of science. Emphasizing interdisciplinary approaches, the program prioritizes proposals that broaden participation in science, engage diverse teams, and support America's leadership in global scientific innovation. The goal is to create impactful, evidence-based policies and advance the science of science.