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Best Oconee County Grants for Nonprofits in South Carolina

Looking for grants for 501(c)(3) nonprofit organizations working in Oconee County, South Carolina? Find the perfect grant for your nonprofit on Instrumentl.

9,000+

Available grants

$2.62B

Total funding

$5K

Median grant

9,000+ grants
$2.62B total
$5K median

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9,262 Results based on applied filters

BJA FY 2026 Rural Violent Crime Reduction Initiative

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $250,000
The BJA FY 2026 Rural Violent Crime Reduction Initiative aims to empower local law enforcement in rural areas to combat violent crime effectively. This funding opportunity provides resources for personnel, technology, and data analytics to enhance crime prevention strategies. Eligible applicants can utilize updated equipment and training to address specific violent crime challenges, ensuring safer communities through innovative approaches and strategic resource allocation. Applications are due by November 6, 2026.
Crime & Justice Rural Development Community / Public Safety +1 more

Fiscal Year (FY) 2027 Department of War Multidisciplinary Research Program of the University Research Initiative (MURI)

US DOD: Dept. of the Navy, Office of the Chief of Naval Research
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Fiscal Year 2027 Department of War Multidisciplinary Research Program aims to fund innovative research teams from U.S. universities. Established in 1985, this initiative addresses complex challenges faced by the Department of War, fostering collaboration across various scientific disciplines. By integrating world-class faculty and graduate students, the program seeks to cultivate a skilled workforce poised to enhance the U.S. defense capabilities and contribute to the advancement of the defense industrial base.
Engineering Education - Higher Education Science +1 more

BJA FY 2026 Students, Teachers, and Officers Preventing (STOP) School Violence Program

US DOJ: Office of Justice Programs
Federal Government
American Samoa, Guam +4 more
Up to US $2,000,000
The BJA FY 2026 Students, Teachers, and Officers Preventing (STOP) School Violence Program aims to enhance school safety by funding initiatives that train staff and students, develop threat assessment teams, and implement technology solutions like anonymous reporting systems. This program supports effective strategies to identify and mitigate risks of school violence, ensuring students have the tools necessary to foster a secure learning environment while adhering to the guidelines set forth by the STOP School Violence Act.
Community / Public Safety Violence Prevention School Safety +1 more

State Biomonitoring Cooperative Agreement

Dept. of Health & Human Services: Centers for Disease Control & Prevention
Federal Government
American Samoa, Guam +4 more
US $750,000 - US $900,000
The State Biomonitoring Cooperative Agreement aims to enhance public health laboratories' ability to conduct biomonitoring and assess human exposure to environmental chemicals. This funding opportunity emphasizes community investigations, state-level studies, and emerging chemicals not covered in the National Exposure Report. By improving laboratory capacity and fostering collaboration, the initiative seeks to identify harmful exposures and evaluate intervention effectiveness over a three-year period.
Epidemiology & Public Health Environmental Contamination & Pollution Environmental Health

Research to Improve Rigor, Replicability, and Reproducibility in Biomedical and Behavioral Sciences

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Neurological Disorders and Stroke (NINDS) is collaborating with other NIH institutes to enhance rigor and replicability in biomedical and behavioral research. This initiative aims to support projects focused on assessing the impact of improved research practices, developing frameworks for study selection, and measuring the generalizability of findings. Currently, applications are not being solicited, allowing researchers time to prepare collaborative proposals.
Neurological Diseases & Disorders

John H. Prescott Marine Mammal Rescue Assistance Grant (363929)

DOC NOAA - ERA Production
Federal Government
American Samoa, Guam +4 more
Up to US $150,000
The John H. Prescott Marine Mammal Rescue Assistance Grant supports the recovery and care of sick or injured marine mammals through federal assistance to the U.S. National Marine Mammal Stranding and Entanglement Response Networks. Eligible applicants must provide a Prescott Letter of Eligibility, confirming their participation in the network. This program aims to enhance marine mammal health monitoring and response capabilities across the country, ensuring timely and effective interventions for stranded marine life.
Wildlife Management Marine / Ocean Conservation Environmental Health

BJA FY26 DNA Capacity Enhancement for Backlog Reduction (CEBR)—Competitive Grants Program

US DOJ: OJP Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The BJA FY 2026 DNA Capacity Enhancement for Backlog Reduction (CEBR) Competitive Grants Program aims to enhance the capacity of state and local government crime laboratories for processing DNA samples. This program focuses on using DNA technology to improve forensic efficiency and implement Rapid DNA in booking stations. It targets jurisdictions with operational challenges, ensuring fair access to funding. Eligible agencies can apply for both competitive and formula CEBR funding.
Crime & Justice Community / Public Safety Emerging Technology Development

Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required) (363926)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute of Neurological Disorders and Stroke (NINDS) aims to enhance research on Amyotrophic Lateral Sclerosis (ALS) through intermediate patient population expanded access protocols. These protocols will provide investigational drugs to ALS patients while collecting vital data to inform future treatments and care strategies. This initiative seeks to better understand the disease's biomarkers, patient experiences, and the overall impact of investigational therapies, fostering advancements in ALS research and care.
Neurological Diseases & Disorders Stroke Amyotrophic Lateral Sclerosis (ALS)

Research Scholar Grants (RSG) Summer Cycle

American Cancer Society
Association/Society
American Samoa, Guam +4 more
Up to US $215,000

American Cancer Society

The mission of the American Cancer Society is to improve the lives of people with cancer and their families through advocacy, research, and patient support, to ensure everyone has an opportunity to prevent, detect, treat, and survive cancer.

ACS Research Priority Areas

The American Cancer Society (ACS) has identified these 6 areas to categorize and track the research we fund to help advance our mission. Applicants (except Institutional Research Grants and Professor grants) are asked to select at least 1 of these research areas that aligns with their proposal:

  • Etiology (causes of cancer)
  • Obesity/Healthy Eating and Active Living (HEAL)
  • Screening and Diagnosis
  • Treatment
  • Survivorship
  • Health Equity Across the Cancer Continuum

Research Scholar Grants

Research Scholar Grants (RSG) provide support for independent, self-directed researchers.

Applicants' institutions must provide space and other resources customary for independent investigators.

Grant proposals are investigator-initiated and may pursue questions across the cancer research continuum, as long as they fit within an American Cancer Society (ACS) priority research area.

These grants typically contribute to the cost of salaries, consumable supplies, and other miscellaneous items required in the research. 

Research Scholar Grants are funded up to $215,000 per year (direct costs), plus 10% allowable indirect costs, with a project period up to four years.

Cancer / Oncology

Broad Street Children's Foundation Grant

Broad Street Childrens Foundation
Private
United States
Unspecified amount

Who We Are

Broad Street Children's Foundation is committed to providing financial support to privately funded children's homes caring for the orphaned, abandoned and broken children right here in the United States.

Grant Seekers

Broad Street Children's Foundation supports self-sustaining children's homes across the United States that actively foster the development of strong, well-rounded children in their care.

Since the start of the Foundation, over $1,000,000.00 in grants have been donated to children's homes across the country. Additionally, through the Bill and Jackie Hazelgrove Scholarship Program, we have been able to assist a number of young people to continue their education and work towards a college or vocational degree.

Today, the Broad Street Children's Foundation is continuing the dream of it's original founders through the second generation. Equally as dedicated to changing the lives of children in need across America and striving to break the cycle of abuse and neglect for other children and their families.

Child Welfare Services Vocational & Trade Education Child Abuse & Neglect +2 more

Easement Restoration and Stewardship

USDA: Natural Resources Conservation Service (NRCS)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $5,000,000
The Easement Restoration and Stewardship program, funded by the USDA NRCS, focuses on restoring and managing Wetland and Floodplain Easements. It includes developing restoration plans, conducting assessments, and implementing stewardship activities to enhance ecological health. Awardees will collaborate with NRCS personnel to ensure effective restoration design and maintenance strategies, fostering sustainable landscapes. This initiative addresses critical habitat conditions and promotes long-term environmental benefits for protected lands.
Habitat & Ecosystem Restoration Freshwater Conservation Land / Habitat Conservation +1 more

OJP FY 2026 Special Attorneys Program Round 9

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The OJP FY 2026 Special Attorneys Program provides funding for state, local, Tribal, and territorial prosecuting agencies to hire qualified prosecutors and support staff. These professionals will work under the National Fraud Enforcement Division to investigate and prosecute crimes committed by criminal aliens, as well as drug and human trafficking cases. This initiative aims to enhance law enforcement capabilities, improve intergovernmental coordination, and strengthen the prosecution of fraud and other serious crimes.
Crime & Justice Community / Public Safety Legal Services +1 more

FY 2027 Notice of Funding Opportunity: Infrastructure Investment and Jobs Act (IIJA) FAA Contract Tower (FCT) Competitive Grant Program

Airport Improvement Program Discretionary Grants
Federal Government
American Samoa, Guam +4 more
US $25,000 - US $55,000,000
The FY 2027 Notice of Funding Opportunity for the Infrastructure Investment and Jobs Act (IIJA) FAA Contract Tower Competitive Grant Program offers up to $100 million for airport traffic control tower projects. This initiative aims to support airports in modernizing and repairing aging infrastructure, ensuring safety and efficiency in air traffic management. Eligible projects may involve construction, rehabilitation, or installation of essential air traffic control equipment, enhancing the operational capabilities of the nation's airports.
Aerospace Engineering Community / Public Safety Emerging Technology Development +1 more

DOJ FY 2026 Assisting Neighborhoods and Governments with Enforcement of Laws (ANGEL) Grant Program

Bureau of Justice Assistance
Federal Government
American Samoa, Guam +4 more
Up to US $500,000
The DOJ FY 2026 ANGEL Grant Program aims to enhance public safety by funding state, local, and tribal government initiatives to combat violent crime committed by criminal illegal aliens. This program supports hiring law enforcement personnel, retaining critical staff, and acquiring advanced technology. The objective is to prevent harm to American citizens and support Homeland Security Task Force operations. Applications must be submitted by October 27, 2026, to qualify for funding.
Crime & Justice Community / Public Safety Violence Prevention

Deployed Warfighter Protection FY27

US DOD: Office of the Secretary of Defense
Federal Government
American Samoa, Guam +4 more
US $20,000 - US $1,100,000
The Deployed Warfighter Protection FY27 program aims to safeguard military personnel from disease-carrying arthropods, including ticks and mosquitoes. It seeks innovative research to develop new insecticides, improve existing formulations, and enhance personal protection technologies. The initiative also focuses on effective pesticide application equipment, addressing both current and emerging arthropod threats. This program is crucial for maintaining the health and safety of deployed military forces.
Infectious & Parasitic Diseases Occupational Health & Safety Preventative Healthcare +1 more

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is seeking to enhance the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) through the establishment of a Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC). This initiative aims to improve emergency care outcomes by supporting trials that focus on effective treatments for non-stroke neurological and cardiovascular emergencies. Although applications are not currently being solicited, this notice allows potential applicants to prepare collaborative proposals.
Health & Medicine Cardiovascular Diseases & Systems Neurological Diseases & Disorders

Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institute on Aging (NIA) is inviting applications for the Alzheimer's Drug-Development Program (U01 Clinical Trial Optional). This initiative seeks to support pre-clinical and early-stage clinical development of innovative drug candidates aimed at preventing Alzheimer's disease or treating its symptoms. The program encourages collaboration among researchers and aims to enhance the therapeutic pipeline for AD through targeted approaches. This notice allows potential applicants time to prepare robust projects.
Dementia & Alzheimer’s Disease

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs

National Institutes of Health
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Institutes of Health (NIH) is dedicated to advancing emergency care through the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN). This initiative seeks to establish clinical enrollment hubs that will enhance the network's ability to conduct trials aimed at improving outcomes for patients experiencing neurological and cardiovascular emergencies. Although applications are not currently being accepted, this notice encourages potential applicants to prepare collaborative and impactful proposals.
Health & Medicine Cardiovascular Diseases & Systems Neurological Diseases & Disorders +1 more

Established Clinician Investigator Award to Support Mentoring (KS1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Established Clinician Investigator Award to Support Mentoring (KS1) is designed to provide established clinician investigators with dedicated time for mentoring early-career clinician research scientists. This initiative by the US Dept. of Health & Human Services: National Institutes of Health (NIH) aims to enhance the quality of mentorship, fostering the development of future leaders in clinical research. It supports a sustained commitment to training and guidance, ensuring a robust pipeline of skilled professionals.
Medical Education & Professional Training Tutoring & Mentoring

Mentored Career Transition Award (KT1/R00)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Career Transition Award (KT1/R00) offers a biphasic funding opportunity for up to 5 years, supporting the transition of postdoctoral researchers to independent faculty positions. The first phase provides 1-2 years of mentored career development, while the second phase grants up to 3 years of independent research support, contingent upon satisfactory progress and faculty appointment. This grant aims to enhance the capacity of early-career researchers in achieving research-intensive roles.
Education - Higher Education Tutoring & Mentoring

Mentored Clinician Research Scientist Career Development Award (KC1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Clinician Research Scientist Career Development Award (KC1) from the NIH supports clinician research scientists for up to five years, providing dedicated time for intensive research career development. This award aims to guide candidates with clinical doctoral degrees towards achieving research independence by pairing them with experienced mentors who can help navigate their career paths.
Education - Higher Education Tutoring & Mentoring

Mentored Research Scientist Career Development Award (KR1)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The Mentored Research Scientist Career Development Award (KR1) offers crucial support for researchers aiming for independence. Funded by the US Dept. of Health & Human Services through the NIH, this award allows candidates to engage in intensive research training under a mentor's guidance for up to five years. It is designed for those with research doctoral degrees, facilitating their transition into independent research roles and enhancing their contributions to the scientific community.
Education - Higher Education Tutoring & Mentoring

Rural Health Network Development Planning Program (363581)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $100,000
The Rural Health Network Development Planning Program aims to enhance rural health care by fostering integrated health care networks. It focuses on collaboration among entities to bolster local capacity and improve care coordination in underserved areas. By achieving efficiencies and expanding access to essential services, the program seeks to strengthen the overall rural health system while promoting the use of health information technology and exploring innovative care delivery models.
Rural Health Care Health Care Access & Delivery

Rural Health Network Development Program (363580)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $300,000 - US $500,000
The Rural Health Network Development Program aims to enhance health care access in rural areas by supporting integrated health care networks. It offers two funding tracts: the Network Advancement Tract for established networks to overcome operational barriers and the Network Development Tract for early-stage networks to plan and expand services. Both tracts focus on improving care coordination, health outcomes, and operational efficiency, thereby strengthening the rural health care system.
Rural Health Care Health Care Access & Delivery

Rural Maternity and Obstetrics Management Strategies Program (363582)

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
Up to US $1,000,000
The Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS) aims to enhance access to maternity and obstetrics care in rural areas through collaborative networks. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative focuses on innovative strategies to improve healthcare delivery for mothers and infants in underserved regions, ensuring that quality care is accessible where it is needed most.
Reproductive Health Women's Health Maternal And Perinatal Health +1 more

Radiation Exposure Screening and Education Program

US HHS: Health Resources & Services Administration (HRSA)
Federal Government
American Samoa, Guam +4 more
US $250,000 - US $500,000
The Radiation Exposure Screening and Education Program aims to support organizations in their efforts to screen and educate individuals who have been exposed to radiation from uranium mining and U.S. nuclear weapons testing. This initiative emphasizes the importance of awareness and education in mitigating health risks associated with radiation exposure, ensuring affected communities receive the necessary resources and support for health management.
Environmental Contamination & Pollution Community / Public Safety

Oconee County Grants for Nonprofits Highlights

Looking for Oconee County grants for nonprofits?


Read more about each grant below or start your 14-day free trial to see all Oconee County grants recommended for your specific programs in South Carolina.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Grant Funding Trends in South Carolina

Average Grant Size

What's the typical amount funded for South Carolina?

Grants are most commonly $74,506.

$74,506

Total Number of Grants

What's the total number of grants in Oconee County Grants for Nonprofits year over year?

In 2024, funders in South Carolina awarded a total of 24,410 grants.

2022 21,855

2023 21,722

2024 24,410

Top Grant Focus Areas

Among all the Oconee County Grants for Nonprofits given out in South Carolina, the most popular focus areas that receive funding are Education, Philanthropy, Voluntarism & Grantmaking Foundations, and Human Services.

1. Education

2. Philanthropy, Voluntarism & Grantmaking Foundations

3. Human Services

Funding Over Time

How is funding for Oconee County Grants for Nonprofits changing over time?

Funding has increased by 22.06%.

2022 $1,534,818,247

2023 $1,485,349,233
-3.22%

2024 $1,813,067,383
22.06%

South Carolina Counties That Receive the Most Funding

How does grant funding vary by county?

Greenville County, Richland County, and Charleston County receive the most funding.

County Total Grant Funding in 2024
Greenville County $580,646,902
Richland County $413,417,941
Charleston County $355,724,083
Spartanburg County $325,246,878
Pickens County $159,596,081