Best Operating Grants for Nonprofits

Workforce Innovation and Opportunity Act Title I - Dislocated Worker Program Services

The Montana Department of Labor & Industry (MTDLI), in compliance with the Workforce Innovation and Opportunity Act (WIOA), is seeking applications from experienced and qualified organizations to execute essential workforce development through the WIOA Title I - Dislocated Worker Program.

In doing so, the Department is seeking applicants who:

• Implement service deliver strategies that align with the 406 JOBS initiative and America's Talent Strategy, including:
  • use of apprenticeship and pre-apprenticeship training models,
  • training in Industry Recognized Credentials,
  • employer engagement to ensure industry-driven strategies, and
  • outreach to hard to reach populations.
• Coordinate with WIOA core partners.
• Deliver strong performance outcomes with respect to employment, wages, credential attainment, and skill gains.

The Healthy Kids Initiative Grant aims to enhance child health and development from before birth through young adulthood. Launching in 2026, it focuses on Healthy Start, Healthy Families, and Healthy Schools. The initiative supports maternal and infant health, access to pediatric care, and school-based health services. It seeks to create nutritious environments and promote active living, addressing behavioral health care needs to foster lifelong well-being for children and their families in Michigan.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS) health equity

Help with healthcare costs for multiple sclerosis (health equity)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

Health Equity Funds offer help to eligible patients living in areas identified as having increased social and financial needs, as well as higher rates of chronic conditions. Eligibility is determined in part by home address zip code. 

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

The THRIVE Grants program, formerly known as Community Grants, offers funding of up to $10,000 to support initiatives that promote economic mobility for low-income individuals in York County. Managed by the York County Community Foundation, these grants prioritize career development, child and youth development, health, housing, and transportation. Eligible applicants include nonprofit organizations and government agencies dedicated to transforming lives and communities through impactful programs.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Multiple sclerosis (MS)

Help with healthcare costs for Multiple sclerosis (MS)

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the insulating covers of the nerve cells in the brain and spinal cord are damaged. MS is a chronic disease that affects the nervous system.

The ATV/UTV Safety Enhancement Funding, provided by the Wisconsin Department of Natural Resources, supports nonprofit organizations in promoting safe and responsible use of all-terrain and utility-terrain vehicles. This biennial funding, with a minimum of $297,000, is aimed at enhancing education and safety measures related to ATV/UTV operations. Eligible organizations must focus on environmental stewardship, comply with relevant laws, and actively support ATV/UTV clubs, thereby fostering community involvement and responsible recreation.

Career and Technical Education

The goal of the South Dakota Department of Education is for all students to graduate college, career, and life ready. The Division of College, Career and Student Success provides support for students' preparations for postsecondary education and the workforce. Services are connected to approved Career & Technical Education (CTE) programs, work-based learning, student organizations and more. In-line with the department's aspiration, DCCSS works to ensure students not only graduate from high school, but that they are prepared to navigate the transitions and life events that come after high school.

Workforce Education Grants

In 2013, the South Dakota Legislature established the Workforce Education Fund through SB 235. Part of that fund was designated to provide grants for Career & Technical Education (CTE) programs in secondary schools.

The Workforce Education Grants provide school districts and private, nonprofit entities who provide specialized training in South Dakota the opportunity to make transformative change in career and technical education programs. High quality CTE programs give students the knowledge, skills and experiences to be well prepared for postsecondary education and the workforce. Partnerships among secondary education, postsecondary education, and business & industry lay the foundation for modern CTE programs.

Grant Purpose & Eligibility

The Workforce Education Grants are designed to demonstrate alignment to postsecondary education and South Dakota workforce needs, developing the state's talent pipeline for workforce development and economic growth. Projects must provide work-readiness training, including technical training. Projects cannot include adult basic education, English learner services, or high school equivalency training programs.

Eligible applicants are private, nonprofit entities that provide specialized career and technical services and education as referenced in SDCL 13-13-89. The entities that are awarded grants will serve as fiscal agents through the completion of their projects. All applications must demonstrate commitment by all grant partners to the grant project and its sustainability following the conclusion of the grant.

The Local Public Health Overdose Fatality Review Teams Grant Program, administered by the New Jersey Department of Health, aims to enhance public health responses to overdose fatalities. This initiative will provide $75,000 to 20 local health departments to support their established review teams. These teams will analyze overdose cases, identify systemic gaps, and devise strategies to mitigate future overdoses, ultimately working towards reducing overdose-related deaths in their communities.

The Sidney J. Harris Trust Grant supports organizations in Middlesex County, New Jersey, focusing on services for senior citizens, children's health and education, and public health projects. Established in memory of Mr. Harris, the trust has been providing grants since 1988, typically ranging from $10,000 to $20,000. Eligible applicants must be 501(c)(3) organizations located in Middlesex County and cater to specific community needs.

CDC Foundation

The CDC Foundation helps the Centers for Disease Control and Prevention (CDC) and the public health system save and improve lives by unleashing the power of partnerships to protect the health, safety and security of all communities, everywhere. The CDC Foundation is authorized by Congress to mobilize philanthropic partners, corporations, organizations and individuals to support the critical health protection mission of CDC and the public health system.

The CDC Foundation manages hundreds of programs each year aimed at protecting communities across the country from a variety of health threats—from chronic disease conditions including cardiovascular disease and cancer, to infectious diseases like malaria and HIV to emergency responses, such as Ebola and Zika.

Contractor for Implementation and Evaluation of Healthy Native Babies Project Materials

This RFP request proposals from Tribes, Tribal Serving Organizations (TSOs) and Urban Indian Organizations (UIOs) [T/TSOs/UIOs] to implement and evaluate the updated Healthy Native Babies Project (HNBP) materials within their service areas. This initiative aims to strengthen culturally relevant infant safe sleep education, increase community awareness and support Native families in reducing sleep related infant deaths. Selected T/TSOs/UIOs will adapt, disseminate and assess the use of HNBP materials in ways that reflect the cultural, linguistic and community-specific needs of the Native populations they serve. 

This project is a rapid turnaround project to support T/TSOs/UIOs in:

• Implementing HNBP materials in clinical, community, and family setting
• Training staff and community partners
• Evaluating reach, effectiveness, and community feedback
• Identifying barriers, facilitators, lessons learned, and best practices for future replication

The Pasadena Community Foundation offers Animal Welfare Grants on even years to support nonprofits focused on wildlife welfare and habitat conservation in the greater Pasadena area. Grants range from $5,000 to $15,000 for organizations that create conservation corridors, protect species, and enhance biodiversity. Eligible applicants must be tax-exempt and serve areas defined by the Pasadena Unified School District. This initiative aims to foster a compassionate community for all animals through impactful projects.

About Patient Advocate Foundation

Patient Advocate Foundation is the nation’s most comprehensive nonprofit dedicated to helping patients navigate, access, and afford the care they need—while improving the healthcare system for all.

Who we are and our impact

Patient Advocate Foundation provides financial assistance to help patients afford treatment and cost of living needs, personalized case management to navigate complex healthcare and social needs challenges, and a wide array of resources to empower people to take charge of their health. Since our founding in 1996—and joining forces with the PAN Foundation in 2026—we have helped 3.8 million patients navigate and access care, granted over $7 billion in financial assistance, served 350,000 people through personalized case management and elevated the patient’s voice to drive improvements in the healthcare system.

Eosinophilic esophagitis

Help with healthcare costs for eosinophilic esophagitis

This TotalAssist fund helps you pay for out-of-pocket healthcare costs, including medication copays, coinsurance, and deductibles, health insurance premiums, and other expenses.

About the disease

Eosinophilic Esophagitis (EoE) is a disorder of the esophagus and is increasingly recognized as a major cause of swallowing difficulties in children and adults. It is a chronic disease of the immune system and can be triggered by a food allergy, acid reflux, or an airborne allergy. An allergic trigger causes the immune system to overact which causes many white blood cells, or eosinophils, to collect in the esophagus. This causes the esophagus to become inflamed and not contract properly. The esophagus can also narrow and develop rings or abscesses. This condition can become worse over time.

Regional Conservation Partnership Program - Wisconsin

Benefits

RCPP encourages partners to join in efforts with producers to increase the restoration and sustainable use of soil, water, wildlife and related natural resources on regional or watershed scales. Through RCPP, NRCS and its partners help producers install and maintain conservation activities in selected project areas. Partners leverage RCPP funding in project areas and report on the benefits achieved. The Secretary of Agriculture may also designate up to eight critical conservation areas to focus RCPP assistance.

Funding

Funding for RCPP is allocated evenly to projects in two different categories, state/multi-state and critical conservation areas. Conservation program contracts and easement agreements are implemented through the Agricultural Conservation Easement Program (ACEP), Environmental Quality Incentives Program (EQIP), Conservation Stewardship Program (CSP) or the Healthy Forests Reserve Program (HFRP). NRCS may also utilize the authorities under the Watershed and Flood Prevention Program, other than the Watershed Rehabilitation Program, in the designated critical conservation areas.

The Regional Conservation Partnership Program brings together a wide array of local and national partners, including Indian tribes, nonprofit organizations, state and local governments, private industry, conservation districts, water districts, universities and many others. So far, more than 2,000 partners are engaged in locally-led conservation efforts through RCPP.

The most successful RCPP projects share four common characteristics: they innovate, leverage additional contributions, offer impactful solutions and engage more participants.

The K12 Strong Workforce Program Grant, initiated by California's legislature in 2018, aims to enhance career technical education (CTE) for K-12 local education agencies (LEAs). It fosters collaborations between K-12 schools and community colleges to create effective CTE pathways, ensuring students gain essential skills for successful transitions into higher education and the workforce. The initiative allocates $150 million annually to support innovative CTE programs, driving regional workforce development and addressing labor market demands.

The Rural Maternity and Obstetrics Management Strategies Program (Rural MOMS) aims to enhance access to maternity and obstetrics care in rural areas through collaborative networks. Funded by the US HHS: Health Resources & Services Administration (HRSA), this initiative focuses on innovative strategies to improve healthcare delivery for mothers and infants in underserved regions, ensuring that quality care is accessible where it is needed most.

The CAUSE High School Internship & Nonprofit Grant offers a unique opportunity for local high school students in La Plata County, Colorado, to engage in a hands-on, paid summer internship. This program pairs students with local nonprofits, providing them with mentorship from marketing professionals. Interns will work directly with nonprofit staff to develop social media campaigns and gain valuable skills. Nonprofits will receive an operational grant to support these marketing efforts, fostering a collaborative community environment.

About

Mission

To promote, protect, and improve the health and safety of all Hoosiers.

Vision

Every Hoosier reaches optimal health regardless of where they live, learn, work, or play.

Chronic Disease Screenings and Treatment Services

County: LaGrange

The LaGrange County Health Department will be issuing funds for chronic disease screenings and treatment services. The screenings should be for individuals residing in LaGrange County who are lawful citizens of the United States, with treatment services offered to those meeting screening thresholds. (Core Public Health Services: Chronic Disease Prevention; Access & Linkage to Care)

Division of Early Childhood

The Department of Human Services Division of Early Childhood (DEC) was established as a standalone IDHS division in 2021 to help strengthen and centralize the state's existing child care, home visiting, and early intervention programs, as well as operationalize and create administrative capacity to establish sustainable infrastructure needs in order to streamline services.

Working hand-in-hand with local communities throughout Illinois, the Division of Early Childhood provides low-income, working families with access to quality, affordable child care; administers community-based prevention and intervention programs; and helps all children between the ages of birth to three with disabilities or delays, to learn and grow.

480-50-3708 Migrant and Seasonal Head Start

Description

Scope of Work

Provide a full-day, comprehensive Head Start child development program to children, ages six weeks to six years, from migrant and seasonal farm-worker families. Program includes early childhood education, school readiness, developmental assessment, mental health screening, field trips, project work, immunizations, nutritious meal service and medical and dental examinations, completion of dental and medical treatment for children who need it, social-service referrals and transportation services.

Announcement Type: Renewal

The Merrimack County Savings Bank Foundation, established in 1997 with a $1 million endowment, focuses on improving community life in its service areas in New Hampshire. It allocates 5% of its endowment annually to support non-profit organizations, particularly in civic, arts, social services, and health sectors. The Foundation prioritizes local needs and considers requests from 501(c)(3) organizations, while excluding individuals and lobbying entities from funding.

The Nick Van Pernis Scholarship Fund, established in memory of Nick Van Pernis, supports students from Hawaii's west side pursuing degrees in Marine Science, Biotechnology, Health Sciences, or Early Childhood Education. Eligible applicants must demonstrate financial need, maintain a minimum GPA of 2.0, and engage in community service. Preference is given to prior recipients who continue to meet requirements. This fund aims to empower students to positively impact the lives of Hawaii residents through their chosen careers.

The Bradley Henry Barnes and Leila Upson Barnes Memorial Trust Grant supports health and well-being initiatives for Southington residents through 501(c)(3) nonprofit organizations. Grants typically range from $25,000 to $100,000, with funding priorities including healthcare for the aging population, mental health, and access to healthy food. Organizations must demonstrate a connection to Southington and adhere to eligibility criteria. Funding requests are accepted biannually, ensuring collaborative community efforts.

The Kei Lin Foundation Grant, established in 2012 by Margaret Tsai, honors her mother, Kei Lin. This grant supports charitable organizations that provide essential services such as housing, food, and medical assistance to senior citizens and veterans. Priority is given to tax-exempt organizations under 501(c)(3) status. Applicants must adhere to specific guidelines and provide regular reports on fund usage to ensure transparency and accountability in their operations.

Department of Mental Health and Addiction Services

The Department of Mental Health and Addiction Services (DMHAS) promotes and administers comprehensive, recovery-oriented services in the areas of mental health treatment and substance abuse prevention and treatment throughout Connecticut.

While the Department's prevention services serve all Connecticut citizens, its mandate is to serve adults (over 18 years of age) with psychiatric or substance use disorders, or both, who lack the financial means to obtain such services on their own. DMHAS also provides collaborative programs for individuals with special needs, such as persons with HIV/AIDS infection, people in the criminal justice system, those with problem gambling disorders, substance abusing pregnant women, persons with traumatic brain injury or hearing impairment, those with co-occurring substance abuse and mental illness, and special populations transitioning out of the Department of Children and Families.

Evidence Based Practices Crisis Intervention Team Training Provider

Program Overview

The State of Connecticut, represented by DMHAS, in its effort to successfully implement a comprehensive CIT Statewide Model including CIT training, collaboration and partnerships with community members, requests proposals from qualified CIT trained entities to provide submissions that effectively describe a plan to provide CIT Training statewide to law enforcement officers, first responders and behavioral health clinicians.

The statewide CIT Statewide Model and Training is designed to equip law enforcement officers, first responders, dispatch/911, mental health professionals, and other relevant stakeholders with the knowledge, skills, and resources necessary to effectively respond to individuals in crisis.

The Community Charter Network Scholarship, provided by the Central Indiana Community Foundation, assists students from Fall Creek Academy or University Heights Preparatory Academy in covering post-secondary educational expenses. This scholarship aims to support those who demonstrate financial need and excel academically. Eligible applicants include former students of these institutions or residents within the IPS district. Awards vary based on available funds and may cover tuition, fees, and other educational costs.

The AWWA Scholarship Program, specifically the Charles 'Chick' Roberts Scholarship, offers $5,000 to a Pennsylvania student pursuing studies in water technologies. This initiative by the American Water Works Association underscores the importance of nurturing future professionals in the water industry. AWWA, the largest organization for water supply experts, is dedicated to supporting students who aim to make significant contributions to this vital field.

Esther Edie Environmental Scholarship

In 1972, Esther Edie brought together several small environmental protection groups from around the state to form the South Dakota Resources Coalition (SDRC). SDRC’s mission was to preserve and enhance our environment, protect our natural resources, and encourage citizens and businesses to adopt sound environmental practices. In its 40-year existence, SDRC fulfilled its mission through education, legislative advocacy, and litigation. Esther Edie was an effective leader in SDRC’s many projects until she died in 2006.

To provide financial support to students attending a college or university in South Dakota, who is pursuing a career in one of the following areas: Environmental Science, Environmental Geography, Environmental Sociology, Natural Resource Management, or Environmental Law.