Best Operating Grants for Nonprofits

The Mother Cabrini Health Foundation's Access to Healthcare Grant Program aims to enhance equitable access to healthcare across New York State. By addressing barriers faced by underserved populations, the foundation supports initiatives that ensure all individuals receive necessary health services. Grants typically begin at $75,000, focusing on direct service programs that align with the Catholic Church's ethical principles. This funding is crucial for organizations dedicated to improving healthcare outcomes for disadvantaged communities.

The National Institute of Allergy and Infectious Diseases (NIAID) is funding research to enhance drug susceptibility testing (DST) for mycobacteria. This initiative aims to improve testing for tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections, which are on the rise. Current methods are slow and ineffective against drug-resistant strains, making rapid DSTs essential for effective treatment and reducing transmission rates. Innovative approaches, including rapid genotypic and phenotypic methods, will be supported to address these challenges.

The Region One Athletic Fund for Individuals Grant supports students in grades 7-11 in the Region 1 School District, enabling them to enhance their athletic skills and experiences. The Fund prioritizes projects that go beyond traditional funding to develop sportsmanship, teamwork, and discipline. Eligible applicants include students, teachers, and community members proposing initiatives like coaching, training camps, and equipment purchases. Preference is given to programs benefiting students who intend to remain in the Region 1 schools.

The Resilient and Connected Appalachians Grant Program, offered by The Nature Conservancy, provides up to $100,000 for projects that acquire land and easements throughout the Appalachian region. This program emphasizes equitable conservation, aiming to support historically marginalized communities and enhance access to nature while addressing climate change impacts. Projects must demonstrate community engagement and align with the program's goals to protect vital habitats and foster resilience in the face of environmental challenges.

The Bachelor of Science Nursing Loan Repayment Program (BSNLRP) aims to enhance California's healthcare workforce by offering loan repayments to registered nurses who serve in medically underserved areas. Funded through a nominal surcharge, the program provides up to $15,000 in loan repayment for a 12-month service commitment, thereby supporting the delivery of essential healthcare services in qualified facilities across the state.

The Lotte Lenya Competition, established in 1998 by the Kurt Weill Foundation for Music, honors the legacy of renowned actress Lotte Lenya. This unique contest blends acting and vocal skills, targeting performers aged 19-32 from diverse backgrounds. Celebrating its 25th anniversary in 2023, the competition has increased its prize offerings, with over $1.6 million awarded to more than 800 singers. It's a prestigious platform that has propelled many winners to successful careers in musical theater and opera.

The Albertsons Foundation - Southwest supports nonprofit organizations that enhance local communities in the Southwest, focusing on health, hunger, education, veterans, and diversity. Grants typically range from $1,000 to $5,000 for first-time applicants, with higher amounts considered for established organizations. Eligible applicants must have a valid 501(c)(3) designation and serve the community. The foundation does not fund individuals, political or religious organizations, or events.

The National Fish Passage Program (NFPP) offers vital assistance for removing barriers to aquatic life, enhancing safety, and promoting local economies. By investing in projects like culvert replacements and floodplain restorations, the program not only supports native fish populations but also delivers significant economic benefits, estimated at $1.5 million for every $1 million invested. With a recent allocation of $15 million, including $5 million for specific restoration initiatives, NFPP continues to advance aquatic connectivity nationwide.

The Florida Blue Foundation's Driver of Health: Food Security Grants aim to enhance food security for families in vulnerable communities. By improving access to affordable, nutritious food, the initiative seeks to mitigate health risks associated with food insecurity. Eligible applicants include nonprofit organizations and community agencies in Florida, focusing on educational programs that promote self-sufficiency. Priority will be given to areas with high food insecurity, ensuring that targeted populations receive essential support.

The Florida Fish and Wildlife Conservation Commission provides annual funding through the Invasive Plant Management Section to support research and outreach projects aimed at managing invasive plant species. Eligible projects can include studies on herbicide efficacy, seed bank viability, and the development of biological control methods. Collaboration with other agencies is encouraged, and funding typically ranges from $20,000 to $40,000, with a maximum administrative overhead of 10%. This initiative is crucial for maintaining Florida's ecosystems.

The Cooperative Endangered Species Conservation Fund supports habitat conservation through land acquisition grants. Established in 1997, this program aims to minimize conflicts between listed species conservation and land use. The U.S. Fish and Wildlife Service provides matching grants to state agencies for projects that ensure the long-term protection of habitats. By acquiring land or conservation easements, this initiative facilitates species recovery and helps prevent future listings under the Endangered Species Act, enhancing overall ecosystem health.

The North Carolina Forest Service Urban and Community Forestry Financial Assistance Program aims to empower municipalities in achieving sustainable urban and community forestry management. By providing financial support and expertise, the program enhances community living quality through effective forestry practices. It uses specific standards to classify community management levels, fostering progress and celebrating achievements. This initiative encourages collaboration among stakeholders to further urban forestry goals and improve local environments, ultimately contributing to healthier, greener communities.

The Vons Foundation, part of Albertsons Companies, supports nonprofit organizations in Southern California that enhance community health, education, and diversity. Grants typically range from $1,000 to $5,000 for first-time recipients. The foundation prioritizes organizations with a valid 501(c)(3) designation and those that serve local communities. Importantly, the foundation maintains a strong commitment to nondiscrimination in all activities, ensuring an inclusive environment for all stakeholders.

The Mortenson Family Foundation is dedicated to expanding opportunities for children and families living in poverty by promoting equitable access to education, social development, and mental health resources. By partnering with nonprofit organizations and public schools, the foundation aims to empower communities through culturally relevant learning practices and strong engagement with families. Their focus on racial equity and sustained support for children from prenatal to 18 years ensures a holistic approach to overcoming the barriers faced by underserved populations.

The ICWA Fellowship Program offers young professionals a unique opportunity to study global cultures through independent writing fellowships abroad. Over two years, fellows engage in cultural immersion, producing monthly dispatches that contribute to public understanding of foreign affairs. The program seeks candidates who demonstrate promise and curiosity, focusing on enriching public life in the U.S. through understanding of lesser-known topics. Ideal applicants are expected to design compelling projects that enhance local knowledge while adhering to the fellowship's immersive nature.

The Integrated Pest Management Program Grants, awarded by the New Hampshire Department of Agriculture, Markets & Food, aim to promote sustainable pest management practices. Since 1998, these grants support projects that incorporate biological, cultural, and chemical tactics to minimize environmental risks. The program is open to various applicants, including private citizens and organizations, focusing on education and reducing pesticide use to enhance public health and environmental quality. Priority is given to diverse applications, including educational initiatives and urban projects.

The Texas Department of Housing and Community Affairs (TDHCA or the Department) announces a NOFA in HOME funds for single family housing programs under the general set-aside utilizing a reservation system. These funds will be made available to HOME Reservation System Participants after a Reservation System Participation (RSP) Agreement has been ratified. The following activity types are eligible uses of HOME funds awarded under this NOFA: (1) Homeowner Reconstruction Assistance (HRA), and (2) Tenant-Based Rental Assistance (TBRA). 

Johnson County Community Development Office

The mission of the Johnson County Community Development Office is to secure federal, state and local funding for community development activities, to provide leadership in coordinating these activities, and to ensure continued funding through accountable, efficient and effective use of these funds in serving low- to moderate-income residents in Johnson County.

Community Development Block Grant

The Community Development Block Grant (CDBG) program provides annual grants on a formula basis to states, cities, and counties to develop viable urban communities by providing decent housing and a suitable living environment, and by expanding economic opportunities, principally for low- and moderate-income persons. The program is authorized under Title 1 of the Housing and Community Development Act of 1974.

Federal Objective

The primary objective of Title I of the Housing and Community Development Act of 1974, as amended, is to promote “development of viable urban communities, by providing decent housing and a suitable living environment and expanding economic opportunities, principally for persons of low and moderate income.” The Code of Federal Regulations, 24 CFR 570 Subparts A through O, govern how this objective is to be carried out.

Johnson County’s Priority Objectives

The primary goal of the program is to provide federal financial assistance to eligible applicants for the purpose of community development. In pursuit of this goal, the County has identified several strategies in the Plan that applicants should consider when applying. A unit of local government may also use local goals and/or objectives in support of a specific activity for which funds are requested. As stated in the 2025-2029 Consolidated Plan, the priority needs are: Non-Housing Community Development; Affordable Housing; and Homelessness.

The CDBG program includes funding for: 1) Housing Projects; 2) Public Facilities Projects 3) Public Services Projects; and 4) Economic Development Projects

Housing Projects

Eligible Activities

Once the National Objective is determined then the activity must be an eligible housing activity defined at 24 CFR 570.202. 

• Homeowner Rehabilitation: General programs aimed at rehabilitation of existing structures, including substantial rehabilitation programs, which typically bring the property up to local codes and standards. Special purpose programs, including: Energy efficiency programs aimed at improving the energy efficiency of homes; Handicapped accessibility programs; Emergency repair programs that provide for the repair of certain elements of a housing unit in emergency situations; Weatherization programs aimed at improving a home’s ability to withstand the elements
• Home Purchase Activities: CDBG funds may be used to provide direct homeownership assistance to LMI households in two ways.
• Rental Housing Activities: CDBG funds may be used for acquisition of property for an eligible rental housing project. CDBG may also be used to rehabilitate rental housing
• New Construction: Generally, new construction of housing is not eligible under the CDBG program. However, the regulations allow for certain eligible entities to carry out this activity on behalf of the grantee (570.204(c)), known as Community Based Development Organization or CBDO. 
• Services in Connection with Housing may qualify under several eligibility categories of the CDBG regulations

The Texas Department of Housing and Community Affairs (the Department) announces a NOFA of approximately $1,000,000 in HOME funds for single family housing programs under the Contract for Deed (CFD) set-aside under a Reservation System. These funds will be made available to HOME Reservation System Participants with a current Reservation System Participation (RSP) Agreement. 

The Bobby Owen Memorial Scholarship Endowment supports students in Prince George County pursuing careers as firefighters, police officers, or emergency medical providers. Established in 2003 in memory of Bobby Owen, the scholarship aims to assist those who have volunteered in these roles or wish to pursue related training. Eligible applicants must demonstrate financial need and maintain a GPA of 3.0 or higher. All documents must be submitted online by the deadline to be considered.

The Workforce Innovation Opportunity Act (WIOA) Youth Funding aims to support marginalized youth aged 18-24 facing barriers to education, training, and employment. Managed by the Office of Workforce Development in collaboration with local organizations, this grant provides funding for up to three years to create a coordinated system that helps youth transition into career-oriented opportunities. Key focus areas include evidence-based policies, partnerships, and access to essential services to ensure successful outcomes for participants.

Ending Epidemics Education, Training and Technical Assistance Services

The intent of this Request for Applications is to support a comprehensive statewide training initiative to strengthen the capacity of local public health agencies, hospitals, community-based organizations, healthcare providers, peer workers, educators, and other partners to improve outcomes for the AIDS Institute’s strategic health priorities. The goal is to reduce health inequities by implementing training and education interventions, such as in-person or virtual trainings, conferences, seminars, digital learning tools, and capacity building initiatives that will prepare providers with the knowledge and skills to mount an effective response to the syndemics of HIV, viral hepatitis, sexually transmitted infections, and substance use disorders. Building upon a foundation of health equity, other priorities for training include the health concerns of the LGBTQAI+ population, the concerns of persons living with HIV across the lifespan (noting the diversity in needs depending on age-related concerns), as well as training around legal and policy initiatives for these syndemic health issues and populations at risk. 

Ending Epidemics in New York State

In June 2014, NYS announced a three-point plan to end the AIDS epidemic in NYS.12 This plan provided a roadmap to significantly reduce HIV infections to a historic low by the end of 2020, with the goal of achieving the first ever decrease in HIV prevalence. The plan also aimed to improve the  health of all HIV positive New Yorkers and was the first jurisdictional effort of its kind in the U.S.

The three points highlighted in the plan are:

• Identify persons with HIV who remain undiagnosed and get them linked to care;
• Link and retain persons diagnosed with HIV in health care to maximize viral suppression;
• Increase access to Pre-Exposure Prophylaxis (PrEP) for persons who are HIV negative.

New York State has been laying groundwork for ending the AIDS epidemic since the disease emerged in the early 1980s. New York State’s response to the HIV/AIDS epidemic has involved the development of comprehensive service delivery systems that evolved over time in sync with the evolution of AIDS from a terminal illness to a manageable chronic disease. This strategy enabled the state to implement new technologies as they were introduced, including new treatments, new diagnostic tests and, more recently, PrEP (pre-exposure prophylaxis). Due to the historic and robust State response over the last 36 years, New York State has bent the curve on the HIV epidemic, reversing the decades-long increase in the number of people in New York State that are diagnosed with HIV. 

Available Funding

Up to $3,094,000 annually in New York State and HRI funding is available to support programs funded through this RFA (total of $15,470,000 in New York State and HRI funding for five (5) years). 

The Tree Fund: Ohio Chapter ISA Education Grant Program, established in 2012, supports arboricultural education initiatives across Ohio. This annual $5,000 grant aims to enhance public awareness and knowledge in arboriculture and urban forestry, benefiting communities and the environment. Eligible applicants include non-profit organizations and educational institutions that serve individuals aged 16 and older, with projects needing hands-on components and solid evaluation metrics to measure impact.

The Jane Bruckel Early Career Investigator Award in Axial Spondyloarthritis, offered by the Spondylitis Association of America, aims to support MDs and PhDs at the Instructor or Assistant Professor level in the US and Canada. This annual $30,000 research grant promotes innovative research in ankylosing spondylitis and enhances patient care by encouraging emerging researchers to contribute to this important field.

The ACWA Scholarship, established by the Association of California Water Agencies in 1961, aims to support innovative students pursuing education in water resources-related fields. This scholarship offers two awards of $3,500 each for qualified undergraduate students, helping to cover tuition and fees for the upcoming academic year. Eligible applicants must be California residents, enrolled in an accredited university, and committed to full-time studies, ensuring the future of California’s water quality management.

About VHFA

Vermont Housing Finance Agency (VHFA) was established in 1974 to finance and promote affordable, safe and decent housing opportunities for low- and moderate-income Vermonters. Each U.S. state has a housing finance agency.

Since its inception, Vermont HFA has helped 31,000 primarily first-time home buyers and their families purchase homes. VHFA provides financing, development and management support, subsidy administration, and tax credits for approximately 9,600 affordable apartments statewide.   

First-Generation Homebuyer Assistance

First-generation homebuyers may be entitled to VHFA grants, which can be used to pay down payments and closing costs. 

These first-time home buyer programs Vermont will remain available until they are used up on a first-come-first-served basis. The funds can be combined with the loan received from the ASSIST program.

$15,000 grant for down payment and closing costs

May be combined with VHFA ASSIST and down payment assistance from other sources

Borrowers and non-borrowing spouses must have NEVER owned a home before and have less than $20,000 combined liquid assets

At least one person taking title must EITHER: have been placed in foster care at some point in their life, OR have parents or legal guardians who never owned or lost their home to foreclosure and have not owned again

Available exclusively with VHFA MOVE, MOVE MCC, or ADVANTAGE. Borrowers and non-borrowing spouses must meet eligibility requirements for selected VHFA Program. Other credit and property eligibility requirements apply. To pre-qualify and apply contact a VHFA Participating Lender!