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Get operating grants for nonprofits covering essential expenses, staffing, program delivery, and organizational sustainability.
33,000+
Available grants
$9.00B
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$6K
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Florida Department of Health
Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.
The Live Like Bella Pediatric Cancer Research Initiative
The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.
The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:
Research Focus
Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus.
Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.
Funding Information
Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.
Grant Categories
Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding.
The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure
Bella Initiative Grant Categories: Emerging Therapeutics and Technologies
This grant category supports research on emerging therapeutics and technologies used in the diagnosis and treatment of cancer and tobacco-related diseases. Examples include but are not limited to personalized/precision medicine therapies, immunotherapy, gene therapy, repurposing of previously used medications, use of artificial intelligence (AI) in diagnosis and treatment, and comparative effectiveness trials of emerging treatments.
Maximum Duration: 36 months
The Community Foundation for a Greater Richmond
The Community Foundation of Richmond is a philanthropic organization dedicated to improving quality of life across the Richmond region by connecting people, ideas, and resources for lasting community impact. The Foundation manages charitable funds, supports local nonprofits, and leads strategic initiatives that address community priorities such as education, health, economic opportunity, and equity. Through grantmaking, donor services, and community leadership, the Foundation works to strengthen nonprofits, respond to emerging needs, and build a more resilient, inclusive, and thriving Richmond-area community.
Virginia Urology Center Scholarship
The Virginia Urology Center Scholarship Program was established in 1999 to benefit graduating seniors from public and private high schools in communities where Virginia Urology offices are located, including Metropolitan Richmond, the Tri-Cities, Northern Neck, Middle Peninsula and South Hill. The scholarship supports post-secondary study in the fields of science and medicine. Funds awarded will help to cover the costs of tuition, room, board, books and laboratory fees.
Ross Community Foundation
The RCF officially became the first affiliate of the Hamilton Community Foundation in 2022, giving it access to collective investments, administrative support, and decades of philanthropic expertise.
Since its inception, the Ross Community Foundation has returned over $90,000 in total to local organizations serving the Ross community. These grants have been able to support a wide variety of needs in our community. Additionally, the Foundation has been able to serve our local nonprofits with continuing education opportunities and other essential needs.
Each year, our board continues to grow the Community Impact Fund through the Community Harvest Campaign, an annual fundraising effort dedicated to ensuring the Foundation can address the changing needs of the community.
Grants for Nonprofits Serving Ross
Purpose: To enhance the quality of life within the Ross Local School District community
The Ross Community Foundation (RCF) supports nonprofit organizations that enhance the quality of life within Ross Local School District communities including Ross Township, Morgan Township, Hanover Township, St. Clair Township, Fairfield Township, and Millville. The Foundation addresses a broad spectrum of community needs, empowering nonprofits to implement impactful programs and services.
Grants are made possible through generous community members who contributed to the Ross Community Foundation Fund. Established in March 2022, the fund has grown significantly, thanks to the support of individuals and businesses dedicated to the betterment of the Ross community.
Funding Priorities
The RCF grant committee awards grants based on need, impact, and merit and prioritizes projects related to education, food availability, and neighborhood needs. Applicants are encouraged to thoroughly demonstrate a need for funding, potentially filling an existing gap in services in the community. Widespread community impact is desired. Self-sustaining projects are preferred.
Geographic Area: Ross Local School District communities including Ross Township, Morgan Township, Hanover Township, St. Clair Township, Fairfield Township, and Millville.
Grant Review Note: RCF may ask applicants to attend a board meeting, conduct a site visit, or conduct a telephone call to obtain additional information. Site visits will be conducted in a group setting, and the applicant will be notified prior to any visit.
About Us
Mission
We enhance the quality of life for all by working together to collectively address challenges and opportunities throughout West Michigan.
Vision
We advance the well-being of our communities by creating the best places to live, learn, work, give, and engage.
Who We Serve
We serve our entire community, without exception. Our commitment is for every individual, family, and organization who works in, visits, or calls the greater Northern Ottawa County area home.
The GHACF is a welcoming place for all people. We believe all people should:
Grant Application Process
The Coopersville Area Community Foundation:
Coopersville Area Grant Program
To begin the process, contact the CACF team to discuss your proposal. We’ll then review your proposal within two weeks of submission to determine whether the project aligns with our grantmaking priorities, and will respond with next steps.
If eligible the appropriate grant application will be made available to you through the online application portal. Grant applications are reviewed with due diligence and may require a follow-up site visit. Lastly, final grant decisions are made with funding recommendations made by the committee and approved through our Board of Trustees.
Texas Education Agency
The Texas Education Agency is the state agency that oversees primary and secondary public education. It is headed by the commissioner of education. The Texas Education Agency improves outcomes for all public school students in the state by providing leadership, guidance, and support to school systems.
The Division of Governance Interventions supports TEA’s mission and vision by providing exceptional leadership, guidance, and support to school system leadership teams and governing boards. The division collaborates with external field support agents appointed by the TEA Commissioner of Education to build sustainable systems aligned to core TEA initiatives, so that the school system thrives after the release of agency intervention.
Legal Framework
Program Description
The purpose of the 2026–2027 Legal Framework grant is to support statewide access to high quality technical assistance and training related to the legal framework of special education through the provision and maintenance of an updated, web based platform. The platform is designed to assist stakeholders—including school systems, advocates, and parents—in understanding and applying state and federal special education laws and regulations.
The program promotes consistent interpretation and implementation of the Individuals with Disabilities Education Act (IDEA) and related state requirements by providing comprehensive, accessible resources that explain the rights of students with disabilities and the obligations of school systems to provide a free appropriate public education (FAPE) in the least restrictive environment (LRE).
Program goals include increasing educator and administrator knowledge of applicable legal requirements, strengthening local implementation practices, and providing timely, accurate, and reliable guidance to support effective special education decision making statewide.
Community Foundation of the Fox River Valley
The Community Foundation of the Fox River Valley is a collection of individual funds and resources given by local citizens to enhance and support the quality of life in the Fox River Valley of Illinois.
We are a tax-exempt public charity that allows individuals, businesses, and non-profit organizations to establish permanent endowments and temporary funds within the confines of one large foundation.
Foundation funds are used to provide grants to non-profit organizations and scholarships to area students. The Foundation also hosts a Youth Engagement in Philanthropy (YEP) program, which helps high school students learn more about philanthropy and empowers them to make a difference in the community.
The Community Foundation of the Fox River Valley serves the City of Aurora, Kane County, and Kendall County within the State of Illinois.
Richard J. & Irma E. Larson Scholarship Endowment Fund
The Richard J. and Irma E. Larson Scholarship Endowment Fund was established to help Aurora area high school graduates attend colleges and universities to further their education in the fields of law, teaching, Christian ministry and agriculture.
Richard, better known as Dick, and Irma are both graduates of Wartburg College in Waverly, Iowa. Dick received his Juris Doctor Degree from the University of Illinois College of Law. Irma earned her Master’s Degree from Northern Illinois University.
Irma has served on several community boards, including Child Welfare, the Aurora YWCA, P.E.O. Chapter DD, and The Mid-West Early American Pressed Glass Club. After retirement, she volunteered as a Court Appointed Special Advocate (CASA) for nine years.
The monetary value of each scholarship award varies depending upon the amount available in each individual scholarship fund. The most common scholarship award amount is $1,000 for a single year. Scholarships are designated as non-renewable one-year awards or renewable multi-year awards depending upon the scholarship fund criteria, as established by the donor of the scholarship fund.
Operating grants for nonprofits provide essential funding to support day-to-day operations, staff salaries, and infrastructure. The following grants help organizations build capacity, maintain sustainability, and focus on achieving their mission-driven goals.
Explore 8,000+ funding opportunities for operational support, with $3.34B in resources. Instrumentl helps nonprofits secure essential funding by offering grant discovery tools, deadline tracking, and strategic funder analysis to ensure long-term success.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits?
Most grants are due in the first quarter.
What's the typical grant amount funded for Operating Grants for Nonprofits?
Grants are most commonly $32,500.
Nonprofits of all types can apply for operating grants, but they are especially useful for organizations needing flexible funding to support the core work of their mission. Operating grants are ideal for nonprofits involved in general population well-being. Specific sectors include healthcare, education, social services, and the arts. Unlike project-based grants that fund specific initiatives, operating grants help with essential costs like staff salaries, rent, and general admin costs. Funders often look for groups with a clear mission who serve a meaningful purpose and have potential for long-term impact.
Based on Instrumentl’s live grant database for operating, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Operating grants exist to help nonprofits function smoothly and grow effectively. The goal is to give organizations the financial means they need to focus on their mission, serve their communities, and support long-term stability. These grants allow nonprofits to improve everyday operations, invest in staff development, and expand programs. Funders want to see nonprofits thrive, not just survive, and providing operational support is a key element to making that happen.
Funding for operating grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Operating grants are often funded by private foundations like the popular Ford Foundation. Some government agencies offer grants to strengthen nonprofit infrastructure, especially in sectors like health, education, and social services. Corporate giving programs may also support nonprofits that align with their values and create lasting impact.
To improve the chances of getting operating grants, nonprofits should:
For more advice on finding and winning operating grants, check out our step-by-step guide to general operating grants.
Instrumentl simplifies the process of applying for operating grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.
Check out how Habitat for Humanity delivered over 200% ROI within just a few weeks.