Best Puerto Rico Grants for Nonprofits

The Gabriella Miller Kids First Pediatric Research Program invites applications for whole genome sequencing of pediatric cohorts. This initiative aims to explore the genetic basis of childhood cancers and congenital anomalies, enhancing our understanding of their etiology. Researchers are encouraged to propose sequencing methods, including whole genome and exome sequencing, to investigate genetic contributions and associations with cancer risk. The resulting data will be integrated into the Kids First Data Resource for broader research collaboration.

The Summer Research Education Experience Program (R25) is designed to enhance educational activities in biomedical and clinical research. This program aims to provide high school and undergraduate students, as well as science teachers, with immersive research experiences during summer breaks. Applications for standard and renewal submissions are due on March 18, 2025, and consecutive years thereafter, while AIDS-related applications are due on May 7 in the same years. Letters of Intent are encouraged.

The National Human Genome Research Institute (NHGRI) is set to release a Notice of Funding Opportunity (NOFO) focused on the ethical, legal, and social implications (ELSI) of genomics. This initiative aims to explore how genomics can enhance health and well-being while addressing its broader societal impacts. The NHGRI encourages applications from diverse academic disciplines to promote innovative and replicable research approaches that effectively analyze the consequences of genomic advancements.

The Innovation in Behavioral Health (IBH) Model (the “Model”) is an eight-year, voluntary service delivery and payment model promoting integrated care in behavioral health (BH) settings. The IBH Model will test the impact of a value-based payment (VBP) model aligned across Medicaid and Medicare that supports an integrated care delivery framework in specialty BH organizations and settings for adult Medicaid, Medicare, and dually eligible beneficiaries with moderate to severe mental health conditions and/or substance use disorders (SUDs).The Centers for Medicare & Medicaid Services (CMS), through its Center for Medicare & Medicaid Innovation (Innovation Center), will select up to eight state Medicaid agencies (SMAs) to participate in the Model. Implementation will begin in January 2025 and end in December 2032. The Model will have an eight-year performance period, which will be comprised of a three-year Pre-Implementation Period along with a five-year Implementation Period. Up to $7.5 million dollars in cooperative agreement award funding will be available to each selected Recipient over the course of the eight years. 

The High Priority HIV and Substance Use Research funding opportunity aims to support innovative research that addresses the intersection of HIV and substance use. Researchers are encouraged to submit proposals that include a detailed research plan and preliminary data, exploring new avenues for prevention, treatment, and potential cures for HIV among people who use drugs. Applications are due by 5 PM local time, with optional Letters of Intent recommended 30 days prior.

Bureau of Justice Assistance

The Bureau of Justice Assistance (BJA) was created in 1984 to reduce violent crime, create safer communities, and reform our Nation’s criminal justice system.

BJA strengthens the Nation’s criminal justice system and helps America’s state, local, and tribal jurisdictions reduce and prevent crime, reduce recidivism, and promote a fair and safe criminal justice system. BJA focuses its programmatic and policy efforts on providing a wide range of resources, including training and technical assistance, to law enforcement, courts, corrections, treatment, reentry, justice information sharing, and community-based partners to address chronic and emerging criminal justice challenges nationwide. 

Special Attorneys Program

This program will support state, local, Tribal, and territorial prosecuting agencies in assigning or hiring qualified prosecutors to serve full time as Special Attorneys within the National Fraud Enforcement Division or the Criminal Division or as Special Assistant United States Attorneys (SAUSAs) within a United States Attorney’s Office. These cross-designated prosecutors will investigate and prosecute fraud and other crimes committed by aliens within the United States (hereafter referred to as “criminal aliens”) and will investigate and prosecute crimes involving drug or human trafficking committed within the United States.

This grant program, authorized under Public Law 119-21, Title X, Subtitle A, Part II, Section 100055 (codified at 34 U.S.C. § 61101), is intended to strengthen investigative and prosecutorial capacity, expand intergovernmental coordination, and enhance the ability of jurisdictions to investigate and prosecute fraud and other crimes committed by aliens within the United States and drug and human trafficking crimes. The program is also intended to increase the availability of cross-designated prosecutorial personnel who can pursue these matters in coordination with federal authorities and contribute to the effective enforcement of applicable criminal laws.

The National Institute on Aging is announcing a Notice of Funding Opportunity for the Claude D. Pepper Older Americans Independence Centers (OAICs) award. This initiative aims to establish centers of excellence in geriatrics research and education to enhance the independence of older adults. Applicants are encouraged to identify a research focus that fosters collaboration and education in aging. Though applications are not currently being accepted, this notice allows potential applicants to prepare meaningful projects. The P30 activity code will be utilized.

The National Institutes of Health is inviting applications for feasibility studies aimed at informing the design of future clinical trials. These studies should demonstrate scientific necessity and may involve mixed methods to assess recruitment, randomization, and intervention delivery. While applications are not currently being solicited, this notice encourages investigators with relevant expertise to prepare for potential collaboration on impactful public health trials.

The NIH Blueprint for Neuroscience Research Network aims to enhance foundational research on human consciousness, addressing critical biomedical issues such as coma and dementia. By fostering a collaborative framework among 14 NIH institutes, the initiative seeks to improve diagnosis and treatment of neurological disorders through interdisciplinary approaches. Key objectives include detecting consciousness in minimally responsive patients, enhancing understanding of sleep disorders, and exploring new methodologies. This effort will ultimately strengthen U.S. leadership in neuroscience and improve patient outcomes.

The Rural Opioid Technical Assistance Centers program aims to provide essential training and technical assistance to combat opioid and stimulant misuse in rural areas. With 10 Regional Centers and a National Coordinating Office, the initiative focuses on high-quality prevention, treatment, and recovery support services for substance use disorders. This program anticipates awarding 11 new grants to enhance community health and safety in addressing polysubstance use challenges.

The National Institute of Neurological Disorders and Stroke (NINDS) aims to support innovative research for validating therapeutic targets in Alzheimer's Disease-Related Dementias (ADRD). This initiative focuses on overcoming barriers in treatment development by ensuring well-validated targets linked to disease mechanisms. By employing a phased award mechanism, NINDS seeks to enhance the rigor of target validation, facilitating the transition from basic discoveries to clinical applications, ultimately accelerating the development of effective therapeutic strategies.

The BRAIN Initiative aims to create web-accessible data archives to enhance research on brain science by offering tools for data analysis and visualization. This effort, led by the National Institute of Mental Health in collaboration with other NIH Institutes, seeks to establish a framework for rigorous data sharing and collaboration across various sub-domains. The initiative will enable the scientific community to access standardized and comprehensive data archives to support innovative neurotechnology research.

The Howard Fellowships, administered by the George A. and Eliza Gardner Howard Foundation, support early mid-career artists and scholars with $40,000 awards for independent projects in selected fields. This unrestricted, non-residency fellowship encourages significant creative development and public visibility through exhibitions or publications. Applicants should demonstrate a promising program of work and must currently reside in the U.S. or its territories. Ten fellowships are awarded annually, promoting artistic and intellectual advancement.

The Hanna H. Gray Fellows Program, funded by the Howard Hughes Medical Institute, aims to enhance diversity in the scientific community by supporting early-career researchers. The program provides funding for postdoctoral training and early faculty years, promoting an inclusive academic culture. Fellows receive an initial salary of $80,000 and a $20,000 annual expense allowance. This initiative helps develop future leaders in biological and biomedical sciences, ensuring equitable opportunities for all backgrounds.

The NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Required) invites applications for high-risk clinical trials that involve multiple centers and aim to change clinical practice or public health. Applicants are encouraged to submit Letters of Intent 30 days before the proposal deadline, with various deadlines set from February 2025 to October 2026. Planning activities must be completed before submission, and consultation with NIDDK staff is advised.

The Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (T35) provides funding to domestic institutions for developing research training opportunities for predoctoral students in biomedical, behavioral, and clinical research. This grant supports short-term research training for health professional students and aims to enhance their exposure to health-related sciences, fostering interest in research careers.

The NIDDK High Risk Multi-Center Clinical Study Cooperative Agreement (U01 Clinical Trial Not Allowed) invites proposals for high-risk, multi-center observational studies on diseases relevant to NIDDK's mission. Applicants are encouraged to consult with NIDDK staff and must complete planning activities before submission. Key deadlines for applications span from February 2025 to October 2026, with optional Letters of Intent due 30 days prior to full proposals.

The Engineering Environmental Resiliency (EER) program, funded by the National Science Foundation, promotes innovative research focused on resource and energy conservation while enhancing environmental protection. By advancing technologies in artificial intelligence, biotechnology, and sustainable manufacturing, EER aims to create resilient U.S. manufacturing systems. Key areas of interest include waste reduction, life cycle assessments, and the interaction of nanomaterials with biological systems, all contributing to a sustainable future.

The Engineering Biological and Biomedical Systems (EBBS) program, funded by the National Science Foundation (NSF), aims to advance our understanding of biological systems and improve human health through innovative engineering solutions. It supports research that combines mechanistic insights with experimental techniques to develop novel biomedical technologies, enhance biomanufacturing processes, and explore therapeutic applications. Projects focusing on engineering principles for biological responses and rehabilitation are encouraged, while drug design and clinical trials are outside the program's scope.

The National Meredith Willson Awards provide multi-year operating support to organizations using music for systemic change. The Music Man Foundation will award grants of $50,000 to $500,000 to 5-10 selected organizations in 2026, focusing on their impact through music. Eligible organizations must have 501(c)(3) status, a history of music programming, and a commitment to systemic change. Applications will be evaluated on leadership, organizational capacity, and alignment with grant criteria.

The Community Facilities Grant Program in Puerto Rico provides essential funding to develop community facilities in rural areas. Eligible projects include healthcare, public safety, and educational services. Grants support up to 75% of project costs for communities with a population under 5,000 and low median household incomes. This program aims to enhance the quality of life in rural areas by funding vital services that foster community growth and support local needs.

The NCAA Postgraduate Scholarship for Spring Sports is awarded to exceptional student-athletes who are in their final year of competition and have maintained a minimum GPA of 3.2. Each year, 126 scholarships of $10,000 are provided, split equally between male and female athletes across various sports. This initiative, established in 1964, aims to promote graduate education and recognizes not just athletic excellence, but also academic achievements and community involvement.

The NCAA Division II Degree Completion Award provides financial assistance to student-athletes who have exhausted their athletics eligibility, enabling them to complete their first undergraduate degree. Since its inception in 2001, nearly $9 million has supported approximately 1,875 athletes, with a remarkable 90 percent graduation rate among recipients. The award covers tuition costs up to $15,000 for remaining credits and may be used in the summer term or short terms surrounding the final undergraduate year.

The NIAID Career Transition Award (K22) supports postdoctoral fellows transitioning to independent research positions, fostering their development into successful biomedical scientists. Key deadlines for applications span from February 2025 to June 2027, including specific dates for standard, renewal, and AIDS-related grants. This initiative, funded by the NIH, aims to enhance the career trajectory of emerging researchers in clinical and biomedical fields, ensuring a robust pipeline of innovative scientific talent.

This funding opportunity aims to address the urgent mental health crisis in the U.S. by promoting research that enhances access to evidence-based practices for youth. It encourages applications focusing on interventions for underserved populations, including those facing housing and food insecurities. Researchers are invited to explore strategies for improving service delivery, overcoming workforce challenges, and integrating care into accessible settings, ultimately striving for equitable mental health services for all youth.

The NCI Continuing Umbrella of Research Experiences (CURE) Mentored Clinical Scientist Research Career Development Award (K08) aims to enhance the careers of clinical scientists committed to cancer research. This NIH-supported program provides protected time for research and encourages underrepresented individuals in health-related sciences. With deadlines spanning from 2025 to 2027, the program focuses on training and developing the skills necessary to compete for significant research funding and address health disparities in cancer research.

This initiative aims to support research interventions targeting disparities in liver diseases and liver cancer among underserved populations in the U.S. It encourages innovative approaches to reduce health inequities and improve health outcomes. The funding opportunity is available through various deadlines for both standard and renewal applications, promoting multi-level strategies to address these critical health issues effectively.