Best Large Grants for Nonprofit Organizations

The Business & Workforce Development Grants aim to bolster California's wood products infrastructure, ensuring the sustainability of forests and supporting the communities reliant on them. Funded through California Climate Investments, this initiative promotes diverse projects that enhance business and workforce development in the forestry sector. Key areas include business development, bioenergy, and forest-related workforce training, all contributing to healthier, resilient forests and a stronger economy, particularly in disadvantaged communities.

The Lynch Foundation Grant supports not-for-profit organizations in the Greater Boston area, focusing on education, health care, religion, and culture. The foundation promotes access to quality education, innovative health programs, and cultural engagement to drive social change. With a commitment to integrity and collaboration, the foundation emphasizes long-term support and sustainability in its grant-making. Organizations are invited to submit concept papers through a rolling application process to align with the foundation's mission of fostering meaningful community impact.

The PCC Foundation offers community grants aimed at enhancing the quality of life in Parke County. These grants, available to both new and existing charitable organizations, support various initiatives including education, health services, and community development. Applications are accepted year-round, with quick decisions for smaller requests. This funding opportunity encourages projects that address community needs and build capacity, fostering a stronger, more resilient community.

The NIDDK Disease Research and Translational Core Centers (P30 Clinical Trial Optional) program invites applications to support innovative biomedical research focused on cystic fibrosis, diabetes, and other chronic diseases. These centers foster collaboration, provide essential resources, and mentor early-stage investigators, enhancing the research landscape. Funding will support pilot programs and access to shared services, ensuring efficient use of resources while promoting a robust scientific community dedicated to advancing health outcomes.

Illinois EPA

The mission of the Illinois EPA is to safeguard environmental quality, consistent with the social and economic needs of the State of Illinois, so as to protect health, welfare, property, and the quality of life.

The Illinois EPA works to safeguard natural resources from pollution to provide a healthy environment. By partnering with businesses, local governments, and the public, the Illinois EPA is dedicated to continued protection of the air we breathe, the water we drink, and the land we live on.

Illinois Clean Ports Program - Deployment

Description

This program of projects is funded by a US EPA Clean Ports Program award that will support the deployment of zero-emission freight-handling equipment such as locomotives, trucks, forklifts, and more. There is also funding for on-site solar generation and battery storage.

This Notice of Funding Opportunity (NOFO) is non-competitive and only open to the six entities that IEPA solicited through a public Call for Partners process in 2024 and then worked with the entities to apply for a successful Clean Ports Deployment grant to US EPA.

The following entities are eligible to apply for this NOFO. The eligible amounts align with the amount IEPA was awarded for that entity in IEPA's Clean Ports - Deployment Agreement with US EPA.

After each eligible applicant's name below, the federal amount is the first amount, followed by the eligible applicant's required match.

• Illinois International Port District; $55,528,309; $6,492,598
• Kaskaskia Regional Port District; $7,421,504; $824,612
• Shawneetown Regional Port District; $1,400,000; $140,000
• Upper Mississippi River International Port District; $7,976,800; $1,754,756
• Rock Island County Metropolitan Mass Transit District; $6,000,000; $750,000
• Zeem Solutions; $6,689,567; $2,112,495

Illinois EPA anticipates processing applications as they are received for this non-competitive NOFO.

The WCF Community Grant Program supports capital projects for small nonprofits in the Flathead Valley, enhancing community welfare. Prioritizing initiatives that demonstrate social need, this funding can help organizations gain recognition and possibly participate in the Great Fish Community Challenge. Eligible applicants must be 501(c)(3) nonprofits or equivalent, benefiting local residents and addressing specific categories such as arts, health, and environment.

The Herbert H. and Grace A. Dow Foundation aims to enhance the educational, economic, cultural, and religious lives of Michigan residents. Grants are made exclusively to 501(c)(3) or governmental organizations in Michigan. The foundation seeks proposals with clearly defined objectives and strong management, prioritizing innovative programs that can achieve long-term sustainability. Collaborations that foster synergy towards common goals are encouraged, while support is not extended to discriminatory or political organizations.

The San Marcos Community Foundation offers Regular Grants ranging from $1,500 to $10,000 to nonprofit organizations benefiting the residents of San Marcos. Established in 1987, the Foundation aims to enhance community quality of life through diverse programs in arts, health, education, and more. Eligible organizations must meet specific requirements, including tax-exempt status. The Foundation prioritizes applications with matching funds at its discretion, fostering a collaborative approach to community enrichment.

The SCC - Jeff Byrd Grant, established by Speedway Children's Charities, honors a dedicated leader by providing a $50,000 grant to support exceptional projects benefiting children. This initiative focuses on addressing local needs, encouraging applicants to collaborate with the Bristol Chapter of SCC. Eligible entities include 501(c)(3) non-profits prioritizing children's welfare in designated Tennessee and Virginia counties. The project must exceed $50,000 in value, ensuring lasting impact on the communities served.

The Green Innovation Grant Program (GIGP) in New York State provides funding for projects that enhance water quality and combat climate change through innovative green technologies. Grants cover up to 90% of construction costs, promoting practices such as green stormwater infrastructure and energy efficiency. Projects are evaluated on their potential impact, sustainability, and ability to foster collaboration. This initiative aims to drive environmental innovation while supporting local communities in addressing pressing ecological challenges.

Rotary Club of Dubois County: Community Grants

The Rotary Club of Dubois County is an active social and service club comprised of dynamic and diverse professionals who make a lasting difference in our community and around the world.

Annually the Club raises funds that are put back into the community through a grant process. The grant is awarded to an organization/ project that aligns with the Rotary seven areas of focus and who provide an opportunity for Rotary Club members to participate and be active in the implementation. Rotary’s seven areas of focus include:

• Basic Education and Literacy;
• Maternal and Child Health;
• Peace and Conflict Prevention/Resolution;
• Disease Prevention and Treatment;
• Clean Water, Sanitation and Hygiene;
• Economic and Community Development;
• Improving the Environment

Complete the application linked above to be considered for this partnership and grant funds of up-to $20,000. 

The Iroquois Community Grant Program, established in 2007, aims to enhance the quality of life in communities hosting Iroquois facilities through funding initiatives focused on environmental preservation, passive recreation, historic preservation, and arts and culture. Grants range from $2,500 to $10,000 and are available to local governments and nonprofit organizations. The program prioritizes projects that demonstrate community involvement and alignment with grant objectives, fostering sustainable benefits for the communities served.

The 2026 Vilcek Prizes for Creative Promise in Biomedical Science will award three $50,000 prizes to exceptional young immigrant scientists in the U.S. This prestigious prize recognizes innovative research contributions in biomedical science. Eligible candidates must be under 38 years old, hold a doctoral degree, and have made significant achievements in their field. The Vilcek Foundation aims to highlight the impact of immigrant scientists on the advancement of biomedical research, fostering diversity and excellence.

The Walter C. Rasmussen-Northeast Bank Foundation honors the legacy of its founder by supporting initiatives in education, housing, culture, environment, and health. With a focus on community-building, the foundation aims to empower the economically disadvantaged, particularly children and families, through self-sufficiency programs. It prioritizes effective strategies that address local needs in Hennepin, Ramsey, and Anoka counties, ensuring a lasting impact on the community's well-being and development.

The Karl H. and Wealtha H. Nelson Family Foundation Grant aims to support charitable organizations in Nebraska City, focusing on health care, historical preservation, education, fine arts, and community development. Established by the Nelson family, the foundation prioritizes projects that enhance the local community's well-being and cultural heritage. The board seeks to fund both established organizations and new initiatives that demonstrate a clear commitment to their goals and community relevance.

The Grace Bersted Foundation Grant supports quality educational, human services, and health care programs for underserved populations, particularly children and the disabled, in DuPage, Kane, Lake, and McHenry counties, Illinois. Established in 1986, it prioritizes organizations with local offices and typically funds grants for one year. Applicants are limited to one submission per calendar year to this and similar foundations, ensuring fair distribution of resources.

The Tobacco Valley Community Foundation (TVCF) offers grants to support local organizations in the Tobacco Valley region, including West Kootenai, Eureka, Rexford, Trego, Fortine, and Stryker. Their mission is to enhance community resources, promote equality, and ensure that residents can actively participate in shaping their futures. By investing in arts, culture, and essential services, TVCF aims to preserve the unique qualities of the area for generations to come.

Immanuel Lutheran Church Grants provide financial support to projects that align with the mission priorities of the Trust Fund. The grants are awarded quarterly and prioritize innovative initiatives that foster community involvement, humanitarian efforts, and spiritual growth. Eligible projects include support for youth, educational stipends, and community service programs. The Trust Fund encourages applications from affiliated organizations and individuals, particularly those that can demonstrate matching funds or unique outreach ideas.

The Diane and Bruce Halle Foundation aims to enhance educational opportunities and outcomes for individuals and communities in Arizona. They focus on funding initiatives that increase access to quality education, especially for low-income students. The foundation prioritizes innovative programs that promote student achievement, college access, and leadership development. Eligible organizations must have 501(c)(3) status, a minimum annual budget, and demonstrate strong management and community engagement.

The Pasadena Community Foundation's Arts & Culture Grants support local nonprofits that enrich the community through arts and culture. Established in 2023, this program focuses on ongoing needs and responses to the Eaton Fire, emphasizing innovation, technology, audience engagement, and collaboration. Eligible organizations must be located within the Pasadena Unified School District and have a record of effective service. Applications are prioritized based on their potential to foster community impact and inclusivity.

The Thomas C. Ackerman Foundation Grant supports K-12 educational programs in San Diego, focusing on mathematics, sciences, arts, and music. Established in 1991, it aims to assist local non-profits in becoming self-sustaining. Organizations eligible for funding must have operated for over a year without prior funding from the Foundation in the last 24 months. The Foundation seeks to address funding challenges faced by local groups while fostering economic development in the community.

Texas Education Agency

The Texas Education Agency is the state agency that oversees primary and secondary public education. It is headed by the commissioner of education. The Texas Education Agency improves outcomes for all public school students in the state by providing leadership, guidance, and support to school systems.

Every Student Succeeds Act (ESSA)

The Every Student Succeeds Act (ESSA) is a federal K–12 education law. ESSA was signed into law in 2015, replacing No Child Left Behind, and reauthorizing the original Elementary and Secondary Education Act (ESEA), which was signed into law in 1965 by President Lyndon Baines Johnson.

ESSA requires every state to measure performance in reading, math, and science. Every school must inform parents about their standards and their results. 

ESSA requires every state to provide parents important information on test performance in reading, math, and science. The report cards must also provide data on graduation rates, suspensions, absenteeism, teacher qualifications, and many other areas. Texas provides maximum transparency for parents and publicly shares performance information on TXschools.gov and in data reports on the Performance Reporting pages.

Every Student Succeeds Act (ESSA) Consolidated Federal Grant

The Every Student Succeeds Act (ESSA) Consolidated Federal Grant includes: 1) Title I, Part A Grants; 2) Title I, Part C Grants; 3) Title I, Part D, Subpart 1 Grants; 4) Title I, Part D, Subpart 2 Grants; 5) Title II, Part A Grants; 6) Title III, Part A ELA Grants; 7) Title III, Part A Immigrant Grants; and 8) Title IV, Part A, Subpart 1 Grants.

Title I, Part D, Subpart 2 

Program Purpose, Goals, and Objectives

[ESSA, Section 1421]

The purpose of Title I, Part D, Subpart 2, is to do the following:

• To carry out high-quality education programs to prepare children and youth for secondary school completion, training, employment, or further education;
• Provide children and youth with the services needed to make a successful transition from institutionalization to further education or employment; and
• To operate programs in local schools, including schools operated or funded by the Bureau of Indian Education for children and youth returning from correctional facilities and programs that may serve at-risk children and youth.

Intended beneficiaries are school systems with high numbers or percentages of children and youth residing in locally-operated (including county-operated) correctional facilities for children and youth. 

The Philadelphia DAO Forfeiture Fund aims to utilize forfeited funds to support community organizations addressing food insecurity, housing instability, and anti-crime initiatives. This fund prioritizes grassroots groups with smaller budgets that help Philadelphians avoid crime and poverty. Eligible organizations must be 501(c)(3) nonprofits based in Philadelphia and have a proven track record of relevant programming. Grants cannot be used for capital projects, and preference is given to programs supporting food access and housing resources.

The Goldman Sachs Community Development Grants Program aims to strengthen low- and moderate-income communities through funding for nonprofits. This initiative includes multi-year unrestricted grants and one-time grants for homeownership initiatives. Eligible organizations must focus on community development, particularly in New York City and parts of New Jersey and Utah. The program emphasizes affordable housing, small business development, and neighborhood revitalization, aligning with the urgent community needs identified through extensive partner consultations.

The John T. & Lois "Sonny" Velkas Child Welfare Fund prioritizes initiatives that enhance the welfare of children in Hancock and Harrison counties. It supports community service, child welfare, education and youth programs, and health and wellness initiatives, aiming for impactful partnerships. Organizations are encouraged to align their proposals with the fund's goals, while noting that lobbying, fundraising events, and administrative costs are ineligible for funding. The fund seeks to foster meaningful community impacts.

The Extension Risk Management Education (ERME) Competitive Grants focus on underutilization of crop insurance projects to enhance agricultural producers' economic viability. This initiative, backed by the Northeast ERME Center and others, provides funding to deliver education in various risk management areas. Grants up to $100,000 are available for projects running from April 2026 to September 2027, with plans to support 7-10 new projects based on quality applications and funding availability.

The Community Fund for Carmel Valley (CFCV) provides grants to nonprofit organizations that support the communities of Carmel Valley, Cachagua, and Jamesburg. It aims to enhance community resources, focusing on community development, youth and senior programming, and educational initiatives. Eligible applicants include 501(c)(3) organizations, public programs, and those with fiscal sponsors. Special consideration is given to local organizations addressing basic needs and emergency responses, ensuring sustainable community benefits.