Best Large Grants for Nonprofit Organizations

The Places and Spaces Program aims to enhance neighborhoods in Hampton by funding collaborative projects that improve public spaces. Eligible organizations can apply for grants up to $150,000 for projects like entryway improvements and community enhancements. Emphasis is placed on inclusivity and strategic planning to ensure that projects reflect community priorities. Applications must be submitted 30 days prior to the grant application deadline, ensuring adequate preparation and community involvement.

Ohio Department of Health

The Ohio Department of Health’s mission is advancing the health and well-being of all Ohioans by transforming the state’s public health system through unique partnerships and funding streams; addressing the community conditions and inequities that lead to disparities in health outcomes; and implementing data-driven, evidence-based solutions.

Trauma-Informed Approaches in Health and Public Health- Summer Funding Opportunity

The Ohio Department of Health Bureau of Health Improvement and Wellness is investing in trauma-informed approaches for health and public health agencies across Ohio. Funding will support qualified contractors to provide coaching, training, facilitation, and organizational planning to help agencies implement trauma-informed practices. This initiative is intended to improve staff wellness and retention, strengthen resiliency-informed organizational culture, and enhance support for patients and clients impacted by trauma and adverse childhood experiences (ACEs).

The City of Bellingham Emergency Repairs Grant allocates $50,000 annually for emergency repairs to multifamily housing, including shelters and transitional housing, as outlined in the City's Consolidated Plan. This initiative has supported over 25,000 individuals through various services in a given year. Applications are processed on a first-come, first-served basis, and additional funding may be available for emergency repairs to nonprofit community facilities serving low-income households.

The Thing 123 Foundation's Community Challenge Grant aims to combat hunger in Elmhurst and surrounding areas by matching donations to build a new Community Food Pantry facility. Established in 1999, the Foundation supports organizations dedicated to enhancing children's lives. This grant will match one dollar for every two dollars donated, up to $100,000, to empower local businesses and community leaders in the fight against food insecurity affecting families and individuals in need.

Notice of Funds Available (RFP): Ohio Developmental Disabilities Council

Untapped Potential

People with I/DD and their family members will have access to services and resources so they can participate fully in their communities.

Annually, key stakeholders will receive information on the benefits and resources to hire people with disabilities. This will allow employment and self-employment outcomes to improve for people with disabilities.

In Ohio, state policymakers are committed to ensuring individuals with developmental disabilities have greater opportunities for employment and advancement of their careers. Individuals with developmental disabilities can use their strengths and talents to increase their income, have a sense of accomplishment and create their own social identity. Employer engagement is essential to furthering this progress.

Hiring people with disabilities is good for business. However, many employers are not aware of this untapped resource or how to effectively recruit, retain and advance people with disabilities.

Business associations in Ohio promote the growth and prosperity of a specific community, region, sector or function of business, by supporting businesses, attracting new investment, and creating jobs. They offer various services like networking opportunities, advocacy, and resources to help businesses grow and thrive within the community. They act as a voice for the region or community and work to improve the local economy. These can include Chambers of Commerce, economic development organizations, safety councils, manufacturing associations, Ohio Means Jobs Centers etc.

Business associations could be a valuable resource in reaching employers who are not aware of this untapped resource. The Ohio Developmental Disabilities Council (ODDC) will fund a project to reach business associations across Ohio to inform them of the benefits of hiring people with disabilities.

ODDC will support activities that build capacity and systemic change through outreach, training, research, technical assistance, supporting and educating communities, interagency collaboration and coordination, demonstration of new approaches, informing policymakers and eliminating barriers, and system design and redesign.

ODDC will provide funding as outlined below for each year of the project. Proposals should address each year of the project. Proposals should address, if necessary: transportation, accessibility, use of technology, replication, sustainability, if the project reaches entire state or a specific region, cross-disability, and cultural diversity.

The Georgia Outdoor Stewardship Grant Program, established in 2018, provides funding for parks, trails, and conservation efforts across Georgia. Administered by the Georgia Department of Natural Resources, the program supports projects that protect wildlife and natural resources. Eligible applicants include local governments and conservation-focused organizations. This initiative, backed by strong voter support, aims to enhance outdoor recreation and safeguard critical lands for future generations.

The Dorrance Family Foundation focuses on enhancing community quality of life through education and conservation initiatives. It funds tax-exempt organizations based in Arizona, California, and the Island of Hawai'i, targeting projects in arts, children's health, animal welfare, and sustainable agriculture. The foundation prioritizes organizations with a history of commitment to their mission. They do not support individuals, ensuring grants are directed towards impactful community projects.

Modeling and Monitoring Air Quality and Co-Benefits of Energy Interventions

The purpose of this solicitation is to fund applied research and development projects that inform California's transition to an equitable, zero-carbon energy system that is climate-resilient and meets environmental goals. Applied research supported by this solicitation will improve existing ambient air quality modeling approaches, advance low-cost measurement technologies, and conduct analyses to quantify the air quality implications and related human health impacts of clean energy interventions across energy use sectors. Ultimately, this research will contribute to a foundation for accurate monetization of non-energy impacts of clean energy interventions.

Improvements in air quality and related human health outcomes are important direct benefits of decarbonizing energy sectors that currently rely on fossil fuels. Capturing these impacts is important to motivate investments in decarbonization strategies but is also a challenging task. Robust air quality modeling and field measurements can help to accurately project the air quality-related benefits and ultimately monetize the human health impacts of clean energy interventions such as implementation of Senate Bill (SB) 100 (SB 100, De León, Chapter 312, Statutes of 2018), transportation electrification, and building electrification.

This solicitation addresses public interest research opportunities at the nexus of human health, air quality monitoring and modeling, and California’s decarbonizing electricity system. Existing ambient air quality simulation models require rigorous evaluation for accuracy of estimates, specific tailoring to California’s complex geography and meteorology, and expanded capability to simulate pollutants such as ozone and secondary particulate matter. Additionally, improvements in the spatial resolution and computational efficiency of existing models are critical to illuminate impacts of decarbonization strategies, and applied research is needed related to low-cost air quality sensors for in-situ household pollution measurement. While existing sensors enable collection of abundant data, they can be afflicted by performance issues and associated inaccuracies.

Projects must fall within the following project groups: 

• Group 1: Advancing Ambient Air Quality Modeling Capabilities and Analysis; and
• Group 2: Developing a Low-cost Air Quality Sensor to Assess Household Air Pollution.

New Jersey Department of Health

The scope of work for the public health system is ever-expanding, and the Department is on the frontlines in leading the response to public health challenges. The Department has three primary branches – Public Health Services, Health Systems, and Integrated Health. All work collaboratively toward improving health by strengthening New Jersey’s health system.

Our Mission: Protect the public’s health, promote healthy communities, and continue to improve the quality of health care in New Jersey.

Rural Health Transformation Program: Improving Chronic Disease Outcomes in Rural New Jersey

The Division of Health Promotion, through its Community Health and Wellness Unit (CHWU), announces the availability of funding awarded to the State under the Rural Health Transformation (RHT) Grant Program. This funding opportunity is designed to support innovative and sustainable strategies that improve chronic disease outcomes, increase access to quality healthcare services, address health disparities, and strengthen healthcare systems in rural communities.

The grant seeks to advance community-driven solutions that promote health equity, improve health outcomes, and enhance care coordination across rural health systems.

Purpose and Goals

The purpose of the Rural Health Transformation Grant is to support projects that transform rural healthcare delivery by addressing systemic challenges and community-identified needs. Grant goals include, but are not limited to:

• Improving access to healthcare services in rural and underserved areas
• Strengthening rural healthcare infrastructure and workforce capacity
• Enhancing care coordination and integration of services
• Addressing SDOH impacting rural populations
• Promoting preventive care, wellness, and chronic disease management

Proposed Grant Activities

• Activity 5.2a: NJ Rural Southern Physical Activity and Nutrition Program (NJ R-SPAN)
• Activity 5.2b: Umbrella Hub Organization
• Activity 5.3b: Enhancing Rural Cancer-Focused Healthcare (ERCH)
• Activity 5.3c: Rural Pharmacy Medication Management Therapy Program
• Activity 5.3d: Rural Health Screening and Education
• Activity 5.4b: Safe Communities: Youth Violence Prevention in Rural Communities

Activity 5.3b: Enhancing Rural Cancer-Focused Healthcare (ERCH)

Program Goals: The Enhancing Rural Cancer Healthcare program aims to implement sustainable policy, systems, and environmental change approaches across the rural areas of 8 Regional Chronic Disease Coalitions to reduce the burden of cancer and other chronic and reproductive diseases. There will also be a focus on supporting/providing cancer survivorship care to residents of rural areas. Residents of the rural areas served by this project will receive culturally specific cancer education, outreach, referrals to appropriate screening services, and survivorship care services. These project efforts may reduce cancer incidence and mortality in rural New Jersey.

• Objective 1.1: Reduce cancer mortality and morbidity in New Jersey rural communities.
• Objective 1.2: Establish PSE change strategies to improve the health and well-being of New Jersey rural communities with relation to cancer primary prevention, early detection, and survivorship.
• Objective 1.3: Increased education, outreach, and screening within rural communities related to various cancer, chronic, and reproductive diseases.

The NIHCM Journalism Grants support projects that enhance health reporting and education, targeting critical issues such as healthcare affordability, pharmaceutical pricing, provider market dynamics, and chronic disease management. This initiative emphasizes the importance of informing policymakers and the public on how to improve healthcare quality and access in the U.S. Proposals may also explore the role of artificial intelligence in healthcare delivery. Applications are welcome from journalists, nonprofits, and universities.

The Mid-Atlantic Panel on Aquatic Invasive Species Grant Program invites proposals for funding to tackle aquatic invasive species (AIS) challenges. Key priorities include research on AIS management, innovative control methods, and educational outreach. Eligible applicants range from individuals in government agencies to non-profit organizations. The program seeks to support initiatives that align with the Aquatic Nuisance Species Task Force standards and aims to enhance regional AIS management strategies.

Fairfield County’s Community Foundation

Fairfield County’s Community Foundation works closely with local organizations, nonprofits, businesses, government, and philanthropists to address challenges and identify opportunities to create a stronger, more vibrant region. Informed by three decades of partnering with and serving our community, we have awarded more than $420 million in grants to nonprofits in Fairfield County and beyond.

Fairfield County Food Security Grants

Fairfield County Food Security grants seek to fill unmet needs in underserved communities by strengthening the collaborative efforts of nonprofits and grassroots organizations that are responding to increased demands and community needs. The Community Foundation will award organizations that best demonstrate the potential to make meaningful, measurable changes in our community by centering equity and transforming the systems and structures at the root of inequities. Applications are accepted on a rolling basis, until available funded are expended.

Specifically, the Fairfield County Food Security grants seek to fill unmet needs in underserved communities by strengthening the collaborative efforts of nonprofits responding to the increased demands and community needs, including:  

• Neighborhood food banks and hyperlocal pantry programs (e.g., mutual aid, churches). 
• Grassroots food distribution networks that deliver directly to families and seniors. 
• School and after-school nutrition programs that fill gaps for children and teens. 
• Food pantries at community colleges meet students’ basic needs.
• Services for people reentering the community from incarceration and veterans’ groups expanding food access.
• Local farms and community growers that help supply healthy, culturally relevant foods for underserved communities.
• Advocating for policies related to food access and gaps in food security.

About Us

Mission

The mission of CKCF is Building Stronger Communities Through Charitable Giving. Located in Newton, CKCF is a host foundation to 18 affiliates in the central Kansas region, supporting rural philanthropy.

History

The CKCF based in Newton, Kansas is thriving as a viable community foundation serving Newton while also being host to numerous affiliate community foundations throughout central Kansas. The Central Kansas Community Foundation was originally founded in 1994. Following a stable history serving a tri-county area the foundation merged in 2009 with the well-established Greater Newton Community Foundation. Today, the CKCF continues to demonstrate a commitment to strengthening communities across the entire Central Kansas region.

Wayne Willis Foundation Scholarship Fund

The scholarship was established to provide financial assistance to current graduating high school seniors or college/graduate students who are furthering their careers through a degree in wildlife management or conservation of natural resources.

The Abandoned Mine Drainage Abatement and Treatment Program (AMDATP) is funded by the Marcellus Legacy Fund as established by Act 13 of 2012. This program aims to address the critical issue of Abandoned Mine Drainage (AMD), which significantly impairs over 5,500 miles of Pennsylvania's streams. Eligible projects can receive grants up to $1,000,000, requiring at least a 15% match, focusing on remediation, maintenance, and monitoring of AMD sites.

Partners for Conservation - Illinois Soil and Water Conservation District Grants (FY26)

The Illinois Department of Agriculture (the “Department” or “IDOA”) is issuing this Notice of Funding Opportunity (“NOFO”) to provide grants to cover ordinary and contingent administrative expenses under the Soil and Water Conservation Districts program per the Soil and Water Conservation Districts Act (70 ILCS 405) and Partners for Planning and Conservation 30 ILCS 105/6z-32) Sec. 6z-32.

The Partners for Conservation Program is a long-term, state-supported initiative to protect natural resources and enhance outdoor recreational opportunities in Illinois. Several state agencies share responsibility for administering the Partners for Conservation Fund. The Illinois Department of Agriculture oversees the program's agriculture-related components. Under the Illinois Department of Agriculture, the program implements strategies for maintaining the viability of Illinois' soil and water resources. Soil and Water Conservation Districts assist landowners in natural resource management by providing technical assistance in such areas as soil conservation, water quality protection, wetlands management, flood control, soil erosion control at urban construction sites, stream bank stabilization, recycling, soil interpretation, land use and site suitability, and conservation education.

Local County Soil and Water Conservation Districts in Illinois that provide natural resource management technical assistance to landowners in such areas as soil conservation, water quality protection, wetlands management, flood control, soil erosion, stream bank stabilization, recycling, soil interpretation, land use and site suitability, and conservation education are eligible to apply.

Awards will be made to applicants meeting all eligibility criteria. Applications will be accepted until April 15, 2026. District funding will be awarded on a competitive basis and determined on base operations support and technical training level of District staff according to completion of planner level certification and technical supplemental support. Funding is also established to cover the cost of health insurance. Awards will range from $39,000 to $500,000. The Illinois Department of Agriculture anticipates distributing this amount across 98 awards.

The Pennsylvania Infrastructure Investment Authority Grant Program offers low-interest loans and grants for improvements in drinking water, storm water, and sewage treatment facilities. Eligible entities include municipalities, authorities, and private operators. Total project assistance can reach up to $11 million, or $20 million for multi-municipality projects. Applicants must consult with a PENNVEST Regional Project Specialist prior to submission. This program aims to enhance water management and pollution prevention practices across the state.

Radio Systems Corporation aims to enhance community welfare through its Product Donation Requests program. With over $2 million contributed last year, the initiative focuses on supporting non-profits dedicated to animal welfare and youth education. This year, the goal is to positively impact 14.5 million individuals and pets. The program welcomes applications from eligible organizations, while ensuring that for-profit entities and political campaigns are not considered for donations.

The Environmental Quality Incentives Program (EQIP) supports farmers and ranchers in integrating conservation practices into their operations. It provides financial assistance and resources to enhance agricultural productivity while protecting natural resources. The program particularly focuses on historically underserved groups, ensuring equitable access to USDA services. State priorities include addressing livestock production limitations, soil quality issues, and managing fire risks. Through EQIP, Utah aims to foster sustainable agricultural practices that benefit both the environment and local communities.

The Children's Trust Community Engagement Grant aims to enhance existing programs that support children and families in Miami-Dade County. This funding opportunity encourages organizations to address high-need populations and promote citizen engagement and advocacy. Nonprofits not currently funded by The Children's Trust can apply for grants typically under $20,000 to develop collaborative projects that foster community involvement. The grant focuses on improving access to essential services and empowering local communities.

The Cochran Family Youth Fund Grant aims to enhance the quality of life for children in Winchester and surrounding counties by financing educational, athletic, and community activities. Established by Douglas E. Cochran, this grant emphasizes support for nonprofits dedicated to youth welfare, encouraging projects that demonstrate a history of success in the community. Eligibility is limited to organizations with 501(c)(3) status that serve the local area, excluding sectarian or political uses.

The Ben B. Cheney Foundation Grant supports community improvement projects in areas where Mr. Cheney's lumber company operated. Focused on one-time project grants, the foundation emphasizes sustainability and local support. Eligible applicants include public charities and government units primarily in Washington, Oregon, and California. The foundation prioritizes projects that invest in long-lasting community needs and demonstrate innovative solutions. Since 1975, it has supported over 1,200 organizations, making a significant impact in local communities.

Employ Milwaukee's WIOA In School Youth program aims to connect youth aged 16-24, who are not currently enrolled in school, to employment and educational opportunities. This initiative focuses on providing essential services such as academic tutoring, career planning, and financial literacy to facilitate successful transitions into the workforce. By leveraging community partnerships, the program seeks to create a skilled workforce that meets the needs of local businesses and promotes economic growth in Milwaukee County.

Klamath Water Quality Improvements Grant Program

Interim Measure 11 from the Amended Klamath Hydroelectric Settlement Agreement (KHSA), includes funding to address water quality improvements in the Klamath River via restoration and conservation actions in the Klamath Basin in Oregon. The emphasis of Interim Measure 11 (IM11) is nutrient reduction projects. PacifiCorp, in consultation with the Interim Measures Implementation Committee, developed a list of project categories to be implemented to fulfill the objective of IM11. PacifiCorp has provided funding of up to $6,433,500 for design/engineering and implementation of projects. This funding is administered through the Klamath Water Quality Improvements Grant Program.

After two grant cycles, a total of $4.9 million remains for future restoration and technical assistance projects. The next solicitation for grant applications will be in February 2026.

A Steering Committee, facilitated by the Oregon Department of Environmental Quality (ODEQ), was established to assist OWEB with the program implementation. OWEB is the Fiscal Agent and will award IM11 funds for projects approved by the Steering Committee until the funds are exhausted.

The Steering Committee is comprised of members from the following organizations: Oregon Water Resources Department, ODEQ, Oregon Department of Agriculture, Oregon Department of Fish and Wildlife, National Oceanic Atmospheric Administration, US Fish and Wildlife Service, US Bureau of Reclamation, Yurok Tribe, Karuk Tribe, Klamath Tribes, California Department of Fish and Wildlife, California North Coast Regional Water Quality Control Board and Aquatic Ecosciences.

Funding

• ​Total Remaining Available: $4.9 million
• ​Max Request:​ None
• ​Required Match: 5% Technical Assistance & Restoration (25% is encouraged for Restoration)

Appalachian Regional Commission NOFO

DCA is making available infrastructure funding in Georgia’s Appalachian Regional Commission footprint.  Funding limit per project is $2,000,000 and all applicable match requirements apply.    

Oregon Health Authority

The Oregon Health Authority is at the forefront of lowering and containing costs, improving quality and increasing access to health care in order to improve the lifelong health of people in Oregon.

Mission: Ensuring all people and communities can achieve optimum physical, mental, and social well-being through partnerships, prevention, and access to quality, affordable health care. OHA will transform the health care system in Oregon by: improving the lifelong health of people in Oregon, increasing the quality, reliability, and availability of care for all people in Oregon and lowering or containing the cost of care so it's affordable to everyone.

Traditional Drinking Water Source Protection Grant

The Drinking Water Source Protection Fund (DWSPF) is designed for the protection of drinking water sources. Drinking water sources include watersheds above a public water supply surface water intake and/or the delineated portion of the aquifer supplying water to public water supply wells or springs. 

Traditional Drinking Water Source Protection grants are for projects that promote reducing risks associated within a drinking water source area or the refinement of a drinking water source area. Projects can involve one or more eligible public water systems that are equal partners in the project. 

The Fleishhacker Foundation's Small Arts Grants program offers crucial financial support to small and mid-sized arts organizations in the Bay Area. Designed for nonprofits with budgets between $100,000 and $749,999, this program promotes the presentation of new works by local artists across various disciplines, including theater and visual arts. Grants, typically around $5,000, can be used for a range of operational costs, fostering creativity and cultural expression within communities.

401 Suicide Prevention Call Center EnhancementThe Department of Human Services Division of Behavioral Health and Recovery is seeking to fund the capacity expansion of its Suicide and Crisis Lifelines. Entities applying are expected to answer calls that are geo-routed by county and must be able to respond to text and chat interactions that are routed statewide.

This grant is a performance-based grant. Applicants are expected to demonstrate past performance operating a Suicide and Crisis Lifeline center. For applicants without Lifeline call center experience, proposals must demonstrate the ability to meet the expectations outlined in this Notice of Funding Opportunity (NOFO).Funding Purpose: The general purpose of this program's funding is to Prioritize equitable, efficient, reliable and timely access across call, chat and text for persons experiencing a behavioral health or other crisis. To expand contact center capacity to response to calls, chats and texts in Illinois.