Best Large Grants for Nonprofit Organizations

HUD Continuum of Care Grant

Overview

Each year, the U.S. Department of Housing and Urban Development (HUD) offers a national competitive funding opportunity to Continuums of Care (CoCs) working to end homelessness. On June 1st, 2026, HUD released the fiscal year 2026 Notice of Funding Opportunity (NOFO), see NOFO and CoC Program Competition

UCS serves as Johnson County’s CoC (KS-505) lead agency and collaborative applicant and submits the application annually on behalf of local members. In fiscal year 2024, $1,061,657 was awarded to members of KS-505’s CoC to support 7 programs in Johnson County offering permanent supportive housing, rapid rehousing, homeless data management services and CoC planning support.

The CoC Program (24 CFR part 578):

• Promotes community-wide commitment to ending homelessness
• Provides funding for nonprofit providers, states, and local governments to quickly re-house homeless individuals, youth, families, and persons fleeing domestic/dating violence, sexual assault, and stalking
• Promotes access to and effective utilization of mainstream programs
• Optimizes self-sufficiency among those experiencing homelessness

The Richard King Mellon Foundation invites innovative proposals that align with their 2021-2030 Strategic Plan, aiming to invest over $1.2 billion to enhance opportunities in southwestern Pennsylvania. Their funding focuses on conservation, economic development, economic mobility, health and well-being, organizational effectiveness, and social-impact investments. The General Application offers flexibility without deadlines, allowing for a variety of support types, including project-specific and general operating funding, aimed at enriching community vitality and environmental stewardship.

The Roanoke Women's Foundation offers impactful grants starting at $30,000 across various sectors such as Arts & Culture, Education, Environment, and Health & Human Services. Eligible organizations must be 501(c)(3) tax-exempt, based in or serving the defined Roanoke area, and have a history of at least five years without receiving a grant. The selection process includes proposal reviews and a membership vote in autumn, ensuring community-driven funding.

The Emergency Solutions Grant (ESG) Program, offered by the Missouri Housing Development Commission, aims to provide essential housing assistance to homeless or nearly homeless individuals in Missouri. With an anticipated funding of up to $2,858,041, the program prioritizes activities like rapid re-housing, street outreach, and homelessness prevention. The competitive allocation process ensures funds are effectively used to support community initiatives that stabilize housing and prevent homelessness, aligning with HUD regulations.

The Healthy Harbors Fund, launched by Charleston Waterkeeper and the South Carolina Coastal Conservation League with support from Coastal Community Foundation, aims to enhance water quality in the Charleston Harbor area. The fund, bolstered by a $1 million settlement from a pollution lawsuit, will provide grants to local nonprofits focusing on critical issues such as plastics, bacteria, and climate resilience. This initiative encourages community engagement and aims to tackle pressing environmental challenges in the Lowcountry.

Wisconsin Sea Grant

Wisconsin Sea Grant is a statewide program of basic and applied research, education, outreach and technology transfer dedicated to the stewardship and sustainable use of the nation’s Great Lakes and ocean resources.

Headquartered at the University of Wisconsin-Madison, the institute is housed in the Office of the Vice Chancellor for Research’s Aquatic Sciences Center. Wisconsin Sea Grant is part of a national network of 34 university-based programs funded through the National Sea Grant College Program, National Oceanic and Atmospheric Administration, U.S. Department of Commerce and through matching contributions from participating states and the private sector.

Each year, the program scrutinizes the impact it has on coastal communities, serving people and better understanding the Great Lakes ecosystem. Our 2026 program one sheet provides a summary.

Wisconsin Fellowship in Water-Related Environmental Hazards and Public Health

The University of Wisconsin-Madison Aquatic Sciences Center, home to the University of Wisconsin Water Resources Institute and Wisconsin Sea Grant, in partnership with the Wisconsin Department of Health Services, seeks applicants for a fellowship focused on water-related environmental hazards and public health in Wisconsin.

This two-year fellowship provides an opportunity for a recent Master of Public Health graduate or doctoral graduate to apply their technical expertise to real-world public health challenges while gaining valuable experience working alongside professionals in state government. The fellow will be employed by UW- Madison and stationed full-time with the Wisconsin Department of Health Services.

The fellowship is designed to support both professional development and community impact. Community- engaged science and public health rely on building relationships, fostering trust, and working collaboratively to support informed decision-making. Through this role, the Fellow will gain experience working at this interface, developing and implementing approaches that support communities while learning how to translate scientific knowledge into meaningful public health action.

The Aging and Adult Services: Emergency Solutions Grant Program aims to support non-profits and local government agencies in providing services for individuals and families experiencing homelessness or at risk of homelessness in North Carolina. Funded by the NC Department of Health and Human Services, this program focuses on crisis response and housing solutions to ensure homelessness is rare and brief. Activities include improving emergency shelters and offering essential services to those in need.

Essex County Community Foundation

Since 1998, Essex County Community Foundation (ECCF) has proudly served the 34 unique cities and towns of Essex County. What started as an organization solely dedicated to strengthening our region’s nonprofits, has evolved – along with our communities – to an innovative and deeply connected Foundation inspiring system based social change.

Essex County Community Foundation inspires philanthropy that strengthens the communities of Essex County by managing charitable assets, strengthening and supporting nonprofits, and engaging in strategic community leadership initiatives. Our ultimate goal is to improve the quality of life in the 34 towns and cities of Essex County.

• We help donors of all sizes elevate their giving by managing charitable assets, sharing our local expertise and providing philanthropic guidance and education.
• Essex County’s 4000+ nonprofit organizations are doing smart, innovative work. We support their critical efforts with education, resources and funding.
• To solve our region’s most complex social issues, we invest and engage in community leadership initiatives driven by our Systems Philanthropy approach to change.

Essex County Veterans Fund 

The Essex County Veterans Fund aims to build community and increase access to critical support services for the 30,000 veterans that call Essex County home. Through grant-making and capacity-building, the initiative will leverage collective funding to make a significant difference in the quality of life for these local heroes and their families.

Our investments will be focused on multiple areas across two different rounds of grantmaking in 2026: Honoring Our Veterans and Serving Those Who Served Us. 

Grant Round 2 - Serving Those Who Served Us

Focus Areas

• Health and Wellness – strengthening the capacity of organizations to effectively provide mental health, disability, and other health services to veterans with diverse experiences and needs.

• Basic Needs and Economic Opportunity – increased access to food, clothing, supplies, and housing; career counseling and workforce training.

The Desert Conservation Program, administered by the California Wildlife Conservation Board, aims to protect and restore the Mojave and Colorado Deserts, which are vital for biodiversity and cultural heritage. This initiative, established through the California Desert Conservation Act, focuses on land acquisition, restoration, and enhancing public access while also addressing climate resilience and improving air and water quality. Eligible projects include habitat restoration and scientific studies to support endangered species recovery.

The Clean Water Workforce Capacity Development (CWWCD) Block Grant, administered by Watersheds United Vermont, aims to enhance the capabilities of clean water organizations in Vermont. This funding promotes equitable access for under-resourced entities to engage in essential clean water projects. The grant supports activities that foster community engagement, streamline administrative processes, and cultivate a diverse workforce in clean water project management, ultimately leading to increased effectiveness and impact in local clean water initiatives.

City of Newark - Office of Homeless Services

The City of Newark, Department of Health and Community Wellness, Office of Homeless Services (OHS) is now accepting proposals from Newark organizations for inclusion in the City’s 2026-2027 HUD Entitlement Programs. 

The Homeless Emergency Assistance and Rapid Transition to Housing Act of 2009 (HEARTH Act), signed into law on May 20, 2009, consolidates three of the separate homeless assistance programs administered by HUD under the McKinney-Vento Homeless Assistance Act into a single grant program, and revises the Emergency Shelter Grants program and renames it as the Emergency Solutions Grants (ESG) program. The HEARTH Act also codifies into law the Continuum of Care planning process, a longstanding part of HUD’s application process, to assist homeless people by providing greater coordination in responding to their needs.

Emergency Solutions Grant Program

The change in the program’s name, from Emergency Shelter Grants to Emergency Solutions Grants, reflects the change in the program’s focus from addressing the needs of homeless people in emergency or transitional shelters to assisting people to quickly regain stability in permanent housing after experiencing a housing crisis and/or homelessness.

The City of Newark has the responsibility of making use of ESG funds, as part of implementing a “Continuum of Care” to address the issue of homelessness and to coordinate activities with other non-profit service providers and organizations. This Request For Proposal (RFP) seeks to solicit proposals that will improve the quality of existing emergency shelters for the homeless and provide certain essential and preventative services to address homelessness.

The City of Newark’s ESG program provides resources for the following program components:

• Rapid Re-Housing;
• Homelessness Prevention; and
• Emergency Shelter.

The Alternative Water Supply Grant, supported by Governor DeSantis and the Florida Legislature, allocates $230 million since Fiscal Year 2019-20 to enhance Florida's water systems. This funding emphasizes regional projects addressing critical needs and maximizing benefits, such as reclaimed water, aquifer recharge, and water conservation. Local cooperators must collaborate with their Water Management District to propose projects, which, upon approval, will be submitted to the DEP for funding consideration.

The Aquatic Weed Control Program in North Carolina aims to assist local governments and residents in managing noxious aquatic weed infestations. By promoting education and partnerships, the program seeks to mitigate economic and environmental impacts from these invasive species. It offers resources for both public and private lands, including technical assistance and financial support for effective management strategies. Through these efforts, the program strives to enhance the health of North Carolina's waterways.

About National Fish and Wildlife Foundation (NFWF)

The National Fish and Wildlife Foundation (NFWF) works with partners to foster sustainable and impactful conservation solutions so that people and nature thrive together. Chartered by Congress in 1984, NFWF has grown to become the nation’s largest conservation foundation. Since its founding, NFWF has funded more than 23,900 projects that have generated a total conservation impact of more than $12 billion.About Sustain Our Great Lakes Program

Sustain Our Great Lakes is a public–private partnership designed to sustain, restore and protect fish, wildlife and habitat in the basin by leveraging funding, building conservation capacity, and focusing partners and resources toward key ecological issues. The program achieves this mission, in part, by awarding grants for on-the-ground habitat restoration and enhancement.Funding priorities for this program include:

• Habitat Restoration to Conserve Species and Improve Water Quality
• Expand and Maintain Nature-Based Solutions in Great Lakes Communities
• Invasive Species Control to Protect and Enhance Restored Habitat
• Activate Restored Habitats and Natural Areas

The James River Water Quality Improvement Grant Program, managed by the Virginia Environmental Endowment, aims to enhance water quality through targeted investments. The program focuses on riparian buffer installations, agricultural pollution reduction, living shoreline construction, and stream restoration. Eligible applicants include nonprofits and local governments, with funding prioritized for implementation costs. Proposals must align with established priorities to demonstrate effectiveness in improving the James River's water quality.

The Climate Adaptation and Resiliency Grant Program, established by AB109, aims to support conservation projects that enhance resilience against climate impacts in California. With an initial funding of $20 million from the Greenhouse Gas Reduction Fund, this program focuses on protecting ecosystems, assisting land managers, and increasing carbon sequestration, while aligning with statewide climate strategies and priorities. It seeks to promote environmental benefits and enhance the sustainability of natural and working lands.

Illinois Department of Agriculture

Mission Statement: The Illinois Department of Agriculture will be an advocate for Illinois' agricultural industry and provide the necessary regulatory functions to benefit consumers, agricultural industry, and our natural resources. The agency will strive to promote agri-business in Illinois and throughout the world.​

Climate Pollution Reduction Grant Implementation Grant

Description 

The Illinois Department of Agriculture (IDOA) is implementing the agricultural portion of the inaugural Climate Pollution Reduction Grant (CPRG) Program, known as Climate Smart Agriculture Program. The intent of the program is to promote the implementation of no-till and strip-till practices through the Partners for Conservation (PFC) Program and the State of Illinois Priority Climate Action Plan.

Subrecipient applications will be selected on a first come, first served basis, per county, such that the first application per county will be prioritized up to a 3,000-acre cap per application, pending qualification and verification. If there are remaining program funds after the first application per county is verified, the second application per county will be prioritized up to a 3,000-acre cap per application, and so on.

About Us

Our Mission

We promote and inspire community generosity and giving by bringing together passionate people and resources in our collective efforts to make an enduring difference in the community we love.

Funding Opportunities

We fund projects benefiting Branch County or Colon, Michigan. In making grants, the Community Foundation attempts to understand the specific objectives of each grant request and the long-term benefits the community will receive from the initiative. 

Community Good Grants

These grants support projects and programs that benefit Branch County and Colon.

Currently, BCCF has the following priorities for funding identified:

• Enhancing Youth Mental Health Supports
• Accelerating Workforce Development
• Offering English Language Learning Supports
• Improving Childcare Access

One competitive grant cycle per year by application only.

The WNAN Natural History Research Grant supports research in biological natural history within western North America. Grants of up to $2,500 are available for five authors to assist with travel, supplies, and other research-related expenses. This initiative particularly encourages applicants from institutions where research is not the primary focus, aiming to foster diverse contributions to natural history.

The Catalyze Challenge Grant, managed by Catalyze, is an opportunity for organizations to receive funding for innovative solutions that enhance career-connected learning for youth aged 11-22. With over $4 million available in Round 5, finalists can secure up to $300,000 to implement their ideas. The grant seeks proposals that empower underserved learners through hands-on experiences and meaningful employer partnerships, ultimately impacting over 65,000 young people across the U.S.

The Research Foundation is launching community grants to enhance health access and equity in Kansas City, particularly for Jackson County residents. Eligible nonprofit organizations can receive support for programs that align with the foundation's priorities, including a 10% allowance for indirect costs. The focus is on health-centric missions, ensuring the funding promotes care access and workforce retention in the healthcare sector, while adhering to the foundation's guidelines.

Community Foundation for Mason County, MI

At the Community Foundation for Mason County, we work with donors, grantees, and advisors to address key community issues. As a leader in community philanthropy, building a vibrant community with great opportunities for all, we are focused on advancing education, increasing recreation opportunities, and community and economic development.

The mission of the Community Foundation is to engage donors and connect them with opportunities to make a lasting impact, build community endowment, provide leadership on key issues, and make grants that reflect the communities we serve.

Miller Family Scholarship

This scholarship has been made possible by the generosity of Michael K. Miller, who established the Miller Family Scholarship Fund of the Community Foundation for Mason County. This scholarship is presented to instrumentalists graduating from Ludington High School.

The North Carolina Department of Environmental Quality (NC DEQ) is offering funding for projects addressing PFAS contamination in water systems during its Fall 2023 funding round. Eligible applicants include local government units and non-profit water corporations. Funding supports both planning and construction efforts, enabling systems to assess and implement solutions for PFAS issues. This initiative aims to enhance water quality and public health by tackling emerging contaminants effectively.

The Montana Nita M. Lowey 21st CCLC Grant provides essential funding for Local Educational Agencies and community organizations to enhance academic enrichment opportunities for students during out-of-school time. With a minimum award of $50,000 per year for five years, this grant supports programs that reinforce regular academic activities and foster literacy and educational development, ultimately aiming to improve outcomes for students and families in the community.

The Lafayette County Bluebird Society Legacy Fund (LCBS) is dedicated to supporting bird conservation initiatives and educational programs in the Driftless Area of southwest Wisconsin. Managed by the Community Foundation of Southern Wisconsin, the fund prioritizes projects that include Lafayette County and organizations whose main mission aligns with bird conservation. Grant applications are reviewed by a volunteer advisory board, and requests should ideally not exceed $3,500.

The Riparian Buffer Block Grant, offered by the Vermont Department of Environmental Conservation, supports organizations in establishing native riparian woody buffers. This initiative aims to enhance the ecological integrity of Vermont's waterways by providing funding for the implementation of forested buffers along rivers and streams. Projects must maintain a minimum buffer width of 35 feet and a planting density of 300 stems per acre, promoting sustainable land and water management practices.

The BHACF Community Action Grant provides up to $50,000 to nonprofits with an endowment fund at the Black Hills Area Community Foundation. This grant aims to support innovative projects that leverage community partnerships and sustainable practices. Eligible organizations include 501(c)(3) public charities and schools within specific counties. However, requests for capital campaigns or activities that discriminate against protected groups are not allowed. The grant fosters diverse proposals in arts, education, social services, and more.