Upcoming Webinar
Instrumentl Fall Launch: Grant Work, Leveled Up.
Thu, Oct 29 or Wed, Nov 4 @ 2PM ET

Skip to main content
Main content

Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$8.25B

Total funding

$6K

Median grant

33,000+ grants
$8.25B total
$6K median

Skip the search. Get matched with grants that fit your non-profit.

Skip the search.

Get matched with grants that actually fit.

Smart recommendations based on your profile — in minutes.

Find me grants

Filters

32,600 Results based on applied filters

Harry M. & Edel Y. Ayers Scholarship Fund

Community Foundation of Northeast Alabama
Private
Alabama
Unspecified amount
The Harry M. and Edel Y. Ayers Scholarship Fund, established by the Community Foundation of Northeast Alabama, honors the founders of Consolidated Publishing Company, Inc. This scholarship supports individuals pursuing associate or bachelor's degrees, as well as approved workforce training programs in Alabama. It is a one-time award available for part-time and full-time students at accredited institutions in the U.S., covering tuition, housing, supplies, and fees based on available assets.
Education - Higher Education Workforce Preparation & Job Readiness Academic Scholarship Programs +3 more

The Alice M. Ditson Fund: Organizational Support - Spring Deadline

The Alice M. Ditson Fund
Association/Society
American Samoa, Guam +4 more
Unspecified amount
The Alice M. Ditson Fund provides organizational support for professional performing ensembles and institutions committed to advancing the work of younger and relatively unknown living American composers. Grants are available for general operating or project support, emphasizing contemporary American classical concert music. Eligibility includes organizations without non-profit status if sponsored by a 501(c)(3) entity, while projects featuring American music are prioritized. This funding opportunity encourages innovative performances and fosters greater recognition of emerging talents in the classical music sphere.
Classical Music Opera Dance

Health Care Foundation of the Oranges (HCFO) Grant

The Health Care Foundation Of The Oranges
Private
Essex County, New Jersey
Unspecified amount
The Health Care Foundation of the Oranges (HCFO) addresses critical public health challenges in East Orange, Orange, Irvington, and West Newark. By supporting local nonprofits focused on mental health, food security, and health education, HCFO aims to promote wellness and eliminate barriers to healthy living for vulnerable communities, including the elderly and those in financial distress. Their commitment ensures that everyone has the opportunity to thrive, regardless of their circumstances.
Disability Care & Services Mental Health & Psychiatric Diseases Poverty Alleviation & Services +2 more

See, Test & Treat Grants

College Of American Pathologists Foundation
Private
United States
US $8,000 - US $50,000
The See, Test & Treat Grants, offered by the College of American Pathologists Foundation, aim to enhance community health by providing free breast and cervical cancer screenings. Since 2011, nearly 9,000 women have benefited from these programs, which will expand in 2026 to reach more underserved populations. This initiative empowers pathologists to reduce healthcare disparities through accessible screenings and follow-up care, ensuring prompt results and comprehensive health education for participants.
Breast Cancer Preventative Healthcare Gynecological Cancers

Competitive Grant- Sunbury Fund

Community Giving Foundation
Private
Northumberland County, Pennsylvania, Snyder County, Pennsylvania
Unspecified amount
The Competitive Grant - Sunbury Fund, established by the Community Giving Foundation, aims to address various charitable needs in the Sunbury area. Since 2005, it has focused on health-related goals, encouraging nonprofit and governmental organizations to apply for funding. Eligible projects include those targeting children's health, early childhood development, oral health, issues affecting the working poor, and coronary care. All funds must be used within the Sunbury Hospital service area, ensuring local impact.
Children’s Health & Pediatrics Early Childhood Development Education - Preschool / Early Learning +4 more

Jim and Margie Fegley Orchestral String Scholarship Fund

Berks County Community Foundation
Private
Pennsylvania, United States
Unspecified amount
The Jim and Margie Fegley Orchestral String Scholarship Fund, established in 2013 by Marjorie Fegley, honors her late husband, James E. Fegley. This fund supports Berks County residents pursuing music education, particularly in orchestral strings. Applicants must maintain a GPA of 3.0 or higher and have participated in music programs. The Berks County Community Foundation manages this fund, which contributes significantly to the local arts and education landscape, fostering musical talent in the community.
Education - Higher Education Symphony / Orchestra Academic Scholarship Programs

Women’s Fund of Hawaii Grants

Women's Fund of Hawaii
Private
Hawaii
Up to US $10,000
The Women’s Fund of Hawaii provides grants to programs that empower women and girls across the state. With a focus on financial security, leadership, and addressing barriers such as homelessness and health issues, the fund aims to uplift the community. Prioritizing projects that reflect its core values, the fund supports initiatives led by women for women, ensuring that diverse voices are heard and represented. This commitment fosters a supportive environment for growth and self-determination in Hawaii.
Women & Girl Services Domestic Violence LGBTQIA+ Services +4 more

Valley Water Standard Grants - Stewardship Grants

Santa Clara Valley Water District
State/Local Government
Santa Clara County, California
US $10,001 - US $150,000
The Valley Water Standard Grants - Stewardship Grants program provides $1.87 million in funding for projects aimed at enhancing safe, clean drinking water, water conservation, and environmental stewardship in Santa Clara County. This initiative supports diverse community efforts including pollution cleanups, habitat restoration, and educational programs, requiring a 15% matching contribution. Open to public agencies and nonprofit organizations, it empowers local communities to tackle pressing water and environmental challenges effectively.
Sanitation & Clean Drinking Water Environmental Contamination & Pollution Environmental Conservation +1 more

The Kadel & Gerhardt Internships

Point Foundation
Private
United States
Up to US $7,000
The Kadel & Gerhardt Internships, funded by the Point Foundation, aim to enhance the representation of LGBTQ+ individuals in HIV/AIDS research and advocacy. These internships support academically talented students pursuing unpaid opportunities in the summer of 2025, addressing the critical need for culturally competent care within the community. By investing in future leaders, the program seeks to combat the stigma surrounding HIV and increase access to essential services for those affected.
HIV / AIDS Sexuality & LGBTQIA+ Rights

Cletus Vetter Memorial Scholarship Fund

Defiance Area Foundation Inc.
Private
Defiance County, Ohio
US $1,000
The Cletus Vetter Memorial Scholarship Fund honors the legacy of Cletus Vetter, a dedicated farmer and conservationist. This $1,000 scholarship is awarded to a resident of Defiance County pursuing education in conservation, natural resources, or agriculture. It aims to inspire the next generation to appreciate and engage in vital resource conservation efforts, ensuring that Cletus's passion for nurturing the land continues through future advocates of sustainability.
Agriculture Environmental Conservation Natural Resources +2 more

Housing and Urban Development- Community Development Block Grant (CDBG)

Louisville-Jefferson County Metro Government
State/Local Government
Jefferson County, Kentucky
Unspecified amount
The Housing and Urban Development Competitive Grant from the Louisville-Jefferson County Metro Government aims to support non-profit organizations in their efforts to reduce homelessness. Funded through federal sources such as CDBG, ESG, and HOPWA, this initiative has allocated over $3 million in the past year to enhance services for individuals facing homelessness or living with HIV/AIDS. Organizations are encouraged to propose funding solutions that align with these critical community needs.
Equitable & Affordable Housing Homelessness Services Supportive Housing & Shelters

Pittsburgh Foundation Economic Mobility Grants: Entrepreneurship

Pittsburgh Foundation
Private
Allegheny County, Pennsylvania
US $10,000 - US $75,000
The Pittsburgh Foundation's Economic Mobility Grants: Entrepreneurship aim to support low-income families and communities by enhancing access to entrepreneurship opportunities. Established in 1945, the foundation prioritizes funding for organizations that serve communities disproportionately affected by poverty. Grants typically range from $10,000 to $150,000, with a focus on interventions that promote financial security and economic growth through business ownership and career advancement.
Entrepreneurship Business Development Educational Access & Equity +1 more

Soil & Water Conservation Program

Lower Platte North Natural Resources District (LPNNRD)
State/Local Government
Nebraska
Up to US $12,500
The Soil & Water Conservation Program by the Lower Platte North NRD offers significant cost-share assistance to landowners for implementing conservation practices. Eligible activities include establishing grasslands, constructing terrace systems, and managing irrigation. Funding can cover up to 90% of costs in priority watersheds, ensuring support for sustainable farming and environmental stewardship. This initiative is open to all landowners within the district, promoting eco-friendly practices across various agricultural landscapes.
Water Resource Management Land / Habitat Conservation

Mibor Realtor Foundation Grant

Mibor Foundation Inc
Private
Boone County, Indiana, Brown County, Indiana +10 more
Unspecified amount
The Mibor Realtor Foundation Grant, offered by the Mibor Foundation Inc, aims to combat homelessness in central Indiana by funding 501(c)(3) non-profits. Since its inception, the Foundation has allocated over $3 million to support organizations that provide permanent housing solutions. Eligible entities can request funding up to $20,000, with typical awards ranging from $5,000 to $15,000. The Foundation prioritizes proven housing-based solutions linked with comprehensive support services.
Disaster Relief / Humanitarian Aid Disaster Preparedness Homelessness Services +4 more

NJ Forest Service Urban & Community Forestry Program (NJUCF) Green Communities

State of New Jersey Department of Environmental Protection
State/Local Government
New Jersey
US $5,000 - US $20,000
The NJ Forest Service Urban & Community Forestry Program (NJUCF) Green Communities aims to support local governments in creating a Community Forestry Management Plan (CFMP) and conducting necessary inventories. This initiative, funded by the USDA Forest Service and the New Jersey Shade Tree Fund, offers grants up to $5,000 for a CFMP alone or $20,000 for both the CFMP and inventory. Eligible entities include municipal and county governments.
Forestry Environmental Conservation

Statewide Capital Projects Initiative Grant

United Way of Marshall County
Private
Indiana
US $50,000 - US $1,500,000
The Statewide Capital Projects Initiative Grant provides essential funding to nonprofit organizations in Indiana, aiming to enhance health and human services. With a total of $80 million available in matching capital grants, the initiative supports projects that improve community facilities. It offers two funding tiers, catering to varying project complexities and encourages partnerships for successful implementation. All applicants must demonstrate a commitment to delivering vital services, ensuring that resources are allocated effectively to benefit local communities.
Basic Human Needs Education - Preschool / Early Learning Child Care Services +2 more

Patagonia’s Grassroots Collaborative Program

Patagonia Org
Corporate
Argentina, Australia +20 more
US $5,000 - US $20,000
Patagonia’s Corporate Grant supports grassroots organizations focused on bold, direct-action campaigns that address the root causes of environmental issues. The program emphasizes equity, inclusivity, and long-term change, targeting communities affected by environmental exploitation. Grants are awarded to innovative groups within the US and Canada, fostering civic engagement and measurable objectives. Patagonia prioritizes funding for initiatives that confront systemic bias and promote environmental justice, ensuring that diverse voices are represented in the environmental movement.
Habitat & Ecosystem Restoration Environmental Health Environmental Justice & Advocacy

Altrusa International Grant

Madison Community Foundation
Private
Dane County, Wisconsin
US $1,000 - US $5,000
The Altrusa International Grant, managed by the Madison Community Foundation, supports projects that empower children and youth in education, aid workforce reintegration, and encourage lifelong learning. Established in 1942, the foundation has a mission to foster a generous community through impactful charitable giving. Grants range from $1,000 to $5,000, with an average of $1,200, aimed at making a meaningful difference in the lives of individuals in Madison and Dane County.
Youth Services Educational Access & Equity Workforce Preparation & Job Readiness +2 more

Special Wildlife Funds - IL Habitat Fund

Illinois Department of Natural Resources
State/Local Government
Illinois
US $10,000 - US $300,000
The Illinois Habitat Fund offers competitive grants for preserving and maintaining high-quality habitat lands, aimed at not-for-profit organizations and governmental entities. This initiative, part of the Special Wildlife Funds Grant Program, supports projects aligned with the Illinois Wildlife Action Plan. Successful proposals typically demonstrate reasonable costs, feasible methods, and public access, contributing to targeted ecological goals across Forest, Farmland, and Wetland Campaigns.
Habitat & Ecosystem Restoration Wildlife Management Land / Habitat Conservation

Green Acres State Land Acquisition Program

State of New Jersey Department of Environmental Protection
State/Local Government
New Jersey
Unspecified amount
The Green Acres State Land Acquisition Program, managed by the New Jersey Department of Environmental Protection, focuses on acquiring land for open space from property owners. It aims to preserve areas designated for recreation and conservation, integrating these lands into state parks, forests, and wildlife management areas. The program collaborates with various DEP divisions to ensure effective land management, and it accepts donations and bequests to enhance public access to natural resources.
Forestry Environmental Conservation

WMU Graduate College: Martin Luther King/César Chavez/Rosa Parks Future Faculty Fellowship

Western Michigan University
Private
Michigan
Approximately US $33,000
The Martin Luther King/César Chavez/Rosa Parks Future Faculty Fellowship at Western Michigan University aims to support academically or economically disadvantaged doctoral candidates in their final dissertation stage. Established in 1986, this fellowship provides financial aid averaging around $33,000 to help students complete their degrees. Recipients must fulfill a three-year teaching or administrative obligation at a postsecondary institution in Michigan, ensuring a commitment to education and community service.
Teacher Development & Training Education - Higher Education Disability Care & Services +6 more

Climatetech Testing and Demonstration Assets (TDA) Program

The Massachusetts Clean Energy Center (MassCEC)
State/Local Government
Massachusetts
US $1,000,000 - US $5,000,000
The Climatetech Testing and Demonstration Assets (TDA) Program, offered by the Massachusetts Clean Energy Center (MassCEC), aims to enhance climatetech innovation in Massachusetts. It provides capital grants ranging from $1.5M to $5M to Entrepreneur Support Organizations (ESOs) for shared infrastructure and equipment development. This initiative addresses gaps in the climatetech ecosystem, promoting commercialization and economic growth, while positioning Massachusetts as a leader in clean energy solutions.
Carbon / Greenhouse Gas Reduction Green Economy & Jobs

Local Arts Support Grant

New York State Council on the Arts (NYSCA)
State/Local Government
Kings County, New York
US $2,500 - US $5,000
The Local Arts Support Grant, funded by the New York State Council on the Arts, empowers Brooklyn's artists and arts organizations by providing funding for community engagement projects. Designed for nonprofit organizations and artist-nonprofit partnerships, it supports diverse artistic disciplines and does not require matching funds. In 2025, it distributed $265,000 to 63 projects, enhancing local cultural initiatives through performances, exhibitions, and workshops that foster community involvement and enrich the arts landscape.
Arts / Culture Access & Participation Public / Community Art Writing & Literature +6 more

Kentucky Agricultural Development Fund (KADF) – County Agricultural Investment Program (CAIP) (KY)

Kentucky Agriculture Department
State/Local Government
Kentucky
Up to US $5,000
The Kentucky Agricultural Development Fund (KADF) offers the County Agricultural Investment Program (CAIP) to support agricultural producers in enhancing their farm operations. This program provides cost-share assistance up to $5,000 for various agricultural enterprises, including livestock, horticulture, and energy efficiency initiatives. CAIP aims to improve the diversity and sustainability of farming practices across Kentucky, benefiting producers through financial support for innovative agricultural practices.
Livestock & Ranching Agricultural Crops Farms & Farming +2 more

TC Energy’s Social Impact Program - Build Strong

Tc Energy Foundation
Private
Arizona, Arkansas +38 more
US $2,500 - US $25,000
TC Energy’s Build Strong program supports vital organizations in communities near its operations. By providing grants, scholarships, and in-kind support, the program aims to enhance safety, education, environmental protection, and community well-being. Eligible applicants include non-profits and community groups addressing local needs. Ineligible activities include operational expenses and for-profit endeavors. The program prioritizes projects demonstrating measurable community impact, fostering a collaborative relationship between TC Energy and local stakeholders.
Environmental Conservation Environment Food Security +2 more

Ornis Birding x Lost Birds Expedition Grant

Ornis Birding Expeditions
Corporate
Africa, Asia +3 more
Up to US $5,000
The Ornis Birding x Lost Birds Expedition Grant aims to inspire skilled young birders, aged 18-30, to explore remote regions and rediscover species that have evaded scientific detection for over a decade. Funded by Ornis Birding Expeditions, this grant offers up to $5,000 for innovative expeditions, encouraging participants to submit detailed observations and engage with local communities. The initiative seeks to fill critical gaps in ornithological knowledge while promoting conservation and ecotourism.
Ornithology Adventure Travel & Expeditions

T32 Postdoctoral Fellowship in Mental Health Services Research

Kaiser Permanente
Private
Alameda County, California, Wayne County, Michigan
Unspecified amount
The T32 Postdoctoral Fellowship in Mental Health Services Research is a two-year program supported by the National Institute of Mental Health. It trains emerging researchers in health systems research focusing on mental health and suicide prevention. The fellowship emphasizes mentorship, research methods, and professional development, preparing fellows to secure independent funding. Candidates with PhDs, MDs, or equivalent degrees, especially those from underrepresented backgrounds, are encouraged to apply. More information is available through the program's website.
Mental Health & Psychiatric Diseases Suicide Prevention

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.