Best Large Grants for Nonprofit Organizations

The Lead-Safe Homes Program (LSHP) invites local partner organizations to apply for grant funding aimed at reducing lead hazards in homes across Wisconsin. With up to $4 million available from October 1, 2025, to September 30, 2026, the program seeks to protect children and pregnant women eligible for Medicaid or BadgerCare. Organizations will be selected based on their ability to coordinate and execute lead hazard reduction efforts, ensuring safe environments for vulnerable populations.

The Rob Schorling Fund, managed by the Greater Salina Community Foundation, offers financial support for individuals and families facing expenses related to leukemia and lymphoma treatments. This fund aims to alleviate the burden of medical costs and travel for residents within a 25-mile radius of Saline County, Kansas. Grants are awarded on a first-come, first-served basis, ensuring timely assistance for those in need.

The Schrafft Charitable Trust focuses on the growth of underserved youth (ages 6-21) through neighborhood-based education and economic independence programs in Boston and New Bedford. Eligible nonprofits can apply for Program or General Operating Grants, emphasizing community representation and impactful youth development initiatives. Returning grantees from the past three years may submit a full proposal directly. The Trust does not fund capital expenditures or scholarships, ensuring resources are directed towards meaningful educational opportunities.

The Tri-City Community Foundation Grant aims to enhance the quality of life in Foley, Gulf Shores, and Orange Beach by funding local nonprofits. Established in 2018, this grant supports initiatives in arts, mental health, education, and economic opportunity. Eligible organizations must be IRS-recognized 501(c)(3) entities serving the Tri-City community. The Foundation prioritizes proposals that demonstrate community support and articulate measurable outcomes, with a total of $25,100 available for the grant cycle.

The Southern Oklahoma Memorial Foundation Grant supports non-profit organizations in southern Oklahoma by providing funding for healthcare, education, and social services. Established in 1950, this foundation plays a vital role in enhancing community welfare. Eligible applicants must be recognized 501(c)(3) organizations operating within a 50-mile radius of Ardmore. Grant applications are accepted quarterly, with deadlines on December 1, March 1, June 1, and September 1. This initiative aims to improve the quality of life for area residents.

Hawai‘i State Foundation on Culture and the Arts

The mission of the Hawai‘i State Foundation on Culture and the Arts (SFCA) is to promote, perpetuate, and preserve culture and the arts in Hawai‘i. SFCA funding is provided by the State of Hawai‘i and the National Endowment for the Arts.

Community Arts Grant Program

The Community Arts Grants program (previously called Biennium Grants) supports eligible nonprofit 501(c)3 arts and culture organizations throughout the state. The grant awards funding to organizations supporting programs and projects that advance the arts, culture, and the humanities in the lives of the people of Hawaiʻi.

The legal provisions of the Community Arts Grants are in Sections 9-11 through 9-18 of the Hawaiʻi Revised Statutes. Each fiscal biennium grant budget is contingent on the State fiscal biennium and appropriations from the Hawaiʻi State Legislature and the National Endowment for the Arts. Grants awarded are subject to available funding for the fiscal year.

Grant Categories

Applicants may submit an application for a project to one of the following categories that align with the SFCA Strategic Priorities 2019-2023. Applicants can apply for one or both fiscal years, and the category and project can be the same or different for each year.

• Heritage/Preservation: Heritage and Preservation (Culture) projects are well grounded in the history of Hawaii and the living cultures in Hawaii. Amplify Hawaiian cultural arts, history, and heritage and support communities to advance cultural knowledge, build cultural capacity, and preserve cultural legacies.

• Community Arts, Community Development, Arts and Healing: Community Arts, Community Development, Arts & Healing (Engagement). Art-based community development projects that increase the creative capacity of rural communities and enhance opportunities to experience culture and the arts statewide and within rural communities and underserved populations.

• Arts Education: Arts Education (Education) provides educational opportunities in any arts discipline for arts in the school environment, out-of-school learning, Early Childhood Development, adult life-long learning, and professional development.

• Presenting & Performing Arts: Literacy Arts, Visual Arts, Media Arts, Performing Arts (The Arts). Projects support programs or activities of organizations that present artists in performances, exhibitions, in-residency settings, online format, and televised broadcasts. 

A Community Arts Grant can be requested in the amount of $5,000, $10,000, or $15,000. A 1:1 match is required. This is a reimbursement grant program.

The Mayer and Morris Kaplan Foundation Environment Grant aims to support initiatives that combat climate change, prioritizing efforts to reduce fossil fuel consumption and enhance climate education for young adults. The foundation emphasizes innovative solutions and partnerships to address both immediate and long-term environmental challenges. Areas of focus include climate and clean energy policy, as well as providing scientifically accurate climate change education. By leveraging data and research, the foundation seeks to empower organizations dedicated to creating impactful change.

The Foundation for Health Equity (F4HE) focuses on combating food insecurity in Northwest Philadelphia by supporting tax-exempt organizations. Grants aim to address immediate needs and systemic inequities, funding programs that provide food assistance and promote healthy aging. F4HE prioritizes nonprofits that exemplify both direct service and systemic change, ensuring a fair opportunity for all community members to achieve optimal health. This initiative seeks to empower local organizations and enhance community resilience against hunger.

The Enterprise Mobility™ Philanthropic Giving program focuses on enhancing community engagement through grants aimed at supporting health, education, arts, and disaster relief initiatives. Only Enterprise Mobility team members and their spouses or domestic partners who volunteer with a nonprofit can apply for funding. The program prioritizes sustainable projects that uplift local communities and address pressing social issues, fostering a culture of responsibility and giving back to society.

The Women & Girls’ Fund, established by the Main Street Community Foundation in 2001, supports organizations that empower women and girls in Connecticut. With a focus on senior services, confidence building, and mental health, the fund prioritizes projects that enhance self-sufficiency and promote leadership skills. Collaborations among organizations are encouraged, fostering community connections and addressing critical needs. Grants are available for program and capacity-building initiatives that align with these goals.

The Municipal Sewer Connections Grants, offered by the Montana Department of Natural Resources & Conservation, aim to protect water resources by funding projects that facilitate the transition from individual septic systems to municipal sewer connections. This program, which operates on a first-come, first-served basis, is designed to alleviate the financial burden of such transitions for homeowners, thereby promoting improved water quality and sustainability in Montana.

The MMS Giving Foundation Grant aims to enhance the lives of individuals and communities in the Pacific Northwest through support for education, arts, and community programs. Focused on the Puget Sound region, the Foundation prioritizes funding specific tasks or projects that address pressing needs. Eligible applicants include 501(c)(3) public charities in good standing that are located in King County or neighboring areas. The Foundation does not fund religious or political activities.

The Cletus Vetter Memorial Scholarship Fund honors the legacy of Cletus Vetter, a dedicated farmer and conservationist. This $1,000 scholarship is awarded to a resident of Defiance County pursuing education in conservation, natural resources, or agriculture. It aims to inspire the next generation to appreciate and engage in vital resource conservation efforts, ensuring that Cletus's passion for nurturing the land continues through future advocates of sustainability.

The Dr. John M. Anderson Excellence in Mental Health Award recognizes outstanding mental health professionals in the St. Louis area who significantly contribute to reducing stigma and promoting mental health in the African American community. This award, presented by the St. Louis County Children’s Service Fund, honors individuals who demonstrate a commitment to improving access to mental health services and advocate for the well-being of children and families. Nominations are evaluated through a rigorous scoring process.

The Black Giving Collective (BGC) champions Black-led initiatives in the eight-county region of Rochester, New York, addressing systemic disparities within the Black community. Guided by the 2024 State of Black Rochester report, BGC provides grants ranging from $5,000 to $15,000, focusing on program support, capacity building, technology, and community engagement. Organizations must have Black leadership or membership to apply, ensuring that funding directly impacts and uplifts the community.

The Bono Brothers Memorial Trust Grant supports needy children in Marin County, California, through Catholic charitable organizations. Established in 1962 by Joseph Bono, the Trust awards an average of four grants annually to eligible 501(c)(3) organizations. The funds are intended for the care, support, maintenance, and education of these children, ensuring they receive necessary assistance and resources for a better future.

The Blanche Davis Moore Foundation Grant Program aims to support non-profit organizations that adhere to historic Judeo-Christian principles, particularly those benefiting children under 18 in Nueces County and surrounding areas. Established in 1993, this private foundation primarily funds public charities recognized as tax-exempt by the IRS. Grants are provided for religious, educational, and charitable purposes, with a focus on enhancing the rights of private property and minimizing government intervention.

The Research and Development Grant Program by the Ohio Water Development Authority (OWDA) supports innovative projects in wastewater, water management, solid waste, and energy resource development. Eligible applicants include local government agencies and higher education institutions. Priority is given to proposals that enhance water quality, technology, equity, and resilience. Grants are contingent upon available funding, and applicants are advised to review the Participation Agreement before applying.

TC Energy’s Build Strong program supports vital organizations in communities near its operations. By providing grants, scholarships, and in-kind support, the program aims to enhance safety, education, environmental protection, and community well-being. Eligible applicants include non-profits and community groups addressing local needs. Ineligible activities include operational expenses and for-profit endeavors. The program prioritizes projects demonstrating measurable community impact, fostering a collaborative relationship between TC Energy and local stakeholders.

The Kansas City Royals Foundation Grants Program has distributed over $25 million since 2001, focusing on Literacy and Education, Healthy and Active Communities, and Military and Veteran Support. Key initiatives include scholarships for underrepresented students, youth engagement through sports, and veteran recognition at games. Organizations within the greater Kansas City area are encouraged to apply, particularly those with budgets under $5 million. The foundation prioritizes projects aligning with its strategic pillars, fostering community growth and support.

The KTGF Fellowship Programs, funded by the Klingenstein Third Generation Foundation, offer $100,000 over two years to support post-doctoral and junior faculty research on ADHD and depression in children, particularly from low-income and under-resourced backgrounds. This initiative aims to foster promising early-career scientists while producing impactful research that benefits affected children and families. Applications are accepted from September 1 to December 15, with specific eligibility criteria outlined for candidates.

The Science Policy Fellowship, offered by the American Chemical Society, provides a unique opportunity for trained scientists to engage in public policy. This program enhances understanding of the policy-making process, allowing Fellows to work alongside experienced Government Affairs staff. The Fellowship focuses on key areas such as federal research funding, education in STEM, and environmental policies. Candidates with a strong background in chemical sciences or engineering are encouraged to apply, regardless of holding a doctorate.

The Willamette Health Council offers Community Event Sponsorships to enhance local initiatives in the Marion-Polk region. Grants typically range from $500 to $2,500. Organizations may receive one sponsorship per calendar year, provided their events align with the Council's mission to improve community health. Applications are accepted on a rolling basis, with specific deadlines for review. This funding supports efforts to tackle health disparities and promote equity in healthcare access.

The Green Acres Nonprofit Grant in New Jersey supports tax-exempt organizations aiming to enhance public access to open space for recreation and conservation. This grant fosters the development of outdoor recreational facilities and the stewardship of natural resources. Eligible nonprofits can receive matching funds to acquire land, develop parks, or manage conservation projects, thus ensuring a lasting impact on community well-being and environmental sustainability.

The Substance Abuse Recovery Grant aims to combat substance abuse in collaboration with local entities like the City of Huntington and County Health Department. It supports prevention, education, intervention, and recovery initiatives, including Moral Reconation Therapy and transportation for recovery homes. This grant is available to non-profits and government organizations focused on helping individuals affected by substance abuse. By fostering a supportive environment, the grant seeks to improve community health and reduce substance-related issues.

The Harris and Eliza Kempner Fund's Core Grants Program focuses on Empowered Youth, aiming to address significant challenges faced by Galveston's youth. With a commitment to enhancing mental health support, promoting civic engagement, and ensuring equitable access to resources, the fund seeks to empower young individuals, particularly those from marginalized backgrounds. Through targeted funding, the Kempner Fund strives to create a thriving community where every young person can reach their full potential.

About the DNR

Preserving and enhancing the natural resources of Wisconsin

In keeping with our mission, the DNR is dedicated to working with Wisconsinites while preserving and enhancing the natural resources of Wisconsin. In partnership with individuals and organizations, DNR staff manage fish, wildlife, forests, parks, air and water resources while promoting a healthy, sustainable environment and a full range of outdoor opportunities.

Notice of Intent/Discharge Cost-Share Grants

Eligibility & Purpose:

The DNR and the Department of Agriculture, Trade and Consumer Protection (DATCP) offer cost-share funding grants to governmental units working with owners and operators of livestock operations to meet pollution control requirements imposed by the DNR.