Best Large Grants for Nonprofit Organizations

The Overdose Fatality Review (OFR) Team Development and Implementation Grant by the Minnesota Department of Health aims to enhance the state's response to overdose fatalities. This initiative seeks to provide communities with resources, support, and guidance to effectively establish or improve their OFR processes. Collaboration among local public health and safety organizations is essential, and applicants must submit letters of support to demonstrate commitment. This funding aims to reduce overdose deaths and improve overall public health outcomes.

The Community Funds Grant by the Marshall County Community Foundation supports local organizations with 501(c)(3) status, focusing on charitable initiatives. Grants typically range from $5,000 and are awarded biannually. Eligible projects include start-up costs for new programs, one-time needs, and other specific requests identified by the foundation. However, individuals and projects for sectarian purposes or long-term funding are not eligible. This grant aims to foster philanthropy and enhance community impact.

The Richmond County Savings Foundation, established in 1998, is dedicated to enhancing the Staten Island community through philanthropic efforts. It provides grants up to $5,000 to local nonprofit organizations for program support, event sponsorship, and more. The Foundation focuses on enriching lives by supporting food pantries, education, healthcare, and cultural initiatives. By fostering community growth and ensuring nonprofits are well-supported, RCSF plays a vital role in improving local services and opportunities.

The American Heart Association is inviting proposals for research on the effects of GLP-1 and GIP agonists in individuals with cardiovascular, kidney, and metabolic diseases. This initiative aims to explore how these medications can alleviate the CKM burden. Researchers with expertise in causal inference, machine learning, and cardiovascular research are encouraged to apply, particularly those working in multidisciplinary teams and leveraging various data sources.

The William Penn Foundation's RFP aims to increase the percentage of certified teachers in Philadelphia public schools, addressing the critical shortage of diverse educators. With a focus on pre-k-4 teachers, the initiative promotes effective pathways for pre-service and in-service teachers, including recruitment, improved preparation programs, and support for current teachers. This effort is essential to align the racial and ethnic makeup of educators with the diverse student population, fostering better educational outcomes in the community.

The Advocacy for Child-Serving Systems RFP by the William Penn Foundation aims to enhance educational equity in Philadelphia by increasing the number of certified, diverse teachers. This initiative addresses the significant gap between the racial demographics of students and teachers. By funding strategic outreach and educational efforts, the foundation seeks to mobilize stakeholders to advocate for improved funding in early childhood and K-12 education, ensuring that all children have access to quality education and support.

The Mildred P. McCrystal Memorial Scholarship, established by the Erie County Community Foundation, supports graduates from Erie County high schools pursuing Fine Arts with a focus on Music Performance or Education. Eligible candidates must have completed two years at an accredited university or community college. This scholarship can be renewed for up to three additional years, providing vital financial assistance to continue their educational journey and contribute to the artistic community.

The Gender-Specific Services Grant, offered by the New Jersey Department of Law & Public Safety, aims to support programs that address the unique challenges faced by girls and gender-expansive youth. This initiative fosters safe, inclusive environments where participants can heal from trauma and build confidence. By promoting trust, creativity, and leadership, the grant seeks to empower young people to connect with role models, express their identities, and envision a brighter future.

The Workforce and Economic Development Network of Pennsylvania (WEDnetPA) Grant offers funding for training programs aimed at enhancing the skills of new and existing employees. This initiative is a collaboration between community colleges and educational institutions, designed to address the workforce needs of Pennsylvania's business sector. Applications are accepted year-round, with quarterly approvals, ensuring ongoing support for workforce development.

The NIHCM Foundation's Local Media Award honors outstanding local journalism that enhances understanding of health care issues in the U.S. It aims to recognize reports that improve health care affordability, accessibility, and quality. A $15,000 prize is awarded to the winner. Eligible entries must be published in 2025 and focus on local markets, offering insights relevant to health plans and policymakers. This award encourages innovative reporting that addresses the complexities of the health care system.

Momentum Grants are designed to empower individuals facing poverty in Douglas County, Kansas, by supporting projects that provide educational opportunities and essential resources. These grants focus on helping applicants transition from crisis to stability, fostering community collaboration. Eligible proposals must come from recognized organizations and demonstrate a commitment to inclusivity. The foundation seeks innovative solutions that address local challenges while adhering to strict ineligibility criteria, ensuring funds are allocated effectively for community enhancement.

What We Do

Since our creation by Congress in 1984, NFWF has grown to become the nation’s largest private conservation foundation. We work with both the public and private sectors to protect and restore our nation’s fish, wildlife, plants and habitats for current and future generations.

NFWF supports conservation efforts across all 50 states and U.S. territories. Since our founding, we've funded over 23,300 rigorously evaluated projects, awarded to both large environmental organizations and small local initiatives. We do not fund advocacy or litigation, and do not conduct membership campaigns. Instead, we focus on achieving results and building a better future for our world.

Northern Great Plains Program

The National Fish and Wildlife Foundation (NFWF) is soliciting proposals to voluntarily conserve and restore grasslands and wildlife species in the Northern Great Plains. The goal of the Northern Great Plains program is to maintain and/or improve interconnected grasslands in focal areas to sustain healthy populations of grassland-obligate species while fostering sustainable livelihoods and preserving cultural identities including tribal cultures and food sovereignty. Major funding partners include the U.S. Fish and Wildlife Service, U.S. Forest Service, Natural Resources Conservation Service (NRCS), Bureau of Land Management, Bezos Earth Fund, Marathon Oil, Altria Group, Occidental Petroleum Corporation, and Margret A. Cargill Philanthropies.

Montana State University

Montana State University (MSU), the state’s largest public research university, serves as Montana’s premier land-grant institution dedicated to education, research, and service. Founded in 1893 in Bozeman, MSU provides high-quality, accessible learning opportunities while advancing discoveries that address the needs of Montana, the nation, and the world. With more than 16,000 students and a strong commitment to hands-on, experiential learning, MSU integrates academic excellence with real-world problem-solving across fields such as agriculture, engineering, health, science, and the arts.

Guided by its land-grant mission, MSU prioritizes student success, community engagement, and research that strengthens Montana’s economy and quality of life. The university strives to foster innovation, expand opportunity, and support thriving communities by preparing graduates who are equipped to lead, serve, and contribute meaningfully to society.

Hugh Hastings Memorial Scholarship

This scholarship supports Montana residents with sophomore status who are pursuing a degree from either the College of Agriculture or the College of Arts and Architecture, alternating by year. Applicants must maintain a minimum 2.7 cumulative GPA. Award amounts vary, and the scholarship falls under the Agriculture and Arts and Architecture scopes.

Berkshire Taconic Community Foundation

Since 1987, we have strengthened communities through philanthropy and leadership. We channel generosity where it is needed, bringing together resources and passion to tackle our region’s most pressing issues and create lasting change.

The Region We Serve

Berkshire Taconic Community Foundation serves Berkshire, Columbia, northeast Dutchess and northwest Litchfield counties. This unique area where New York, Connecticut and Massachusetts meet contains 2,200 square miles of natural beauty and small-town charm that is home to nearly 230,000 people.

Fund for Columbia County: General Operating Support Grants

Introduction

Berkshire Taconic Community Foundation established the Fund for Columbia County (FCC) in 1998 to help strengthen communities and improve the quality of life for everyone in Columbia County. The fund serves as a resource for organizations that make life safer, healthier, and more equitable for all residents of the county.

Grants for General Operating Support

Through its General Operating Support Grants, FCC supports organizations that have a deep, lasting, and positive impact on the residents of Columbia County, with particular emphasis on low-income and underserved adults and children.

FCC’s primary focus areas include:

• Youth development
• Education
• Services for the elderly
• Health and social services
• Civic and community engagement through arts, culture, and education

These Grants provide flexible general operating support, which may include:

• Personnel and overhead costs
• Planning and implementation of programs
• Technology, equipment, or material costs
• Strategic planning, staff/board development, and/or succession planning
• Investments to increase organizational capacity
• Other annual operating expenses

Berks County Community Foundation

Berks County Community Foundation was founded in 1994 to help individuals, families, organizations and businesses achieve their charitable objectives. Since that time, the foundation has grown to manage hundreds of charitable funds. Each year, the funds distribute millions of dollars in scholarships and grants to support local students and nonprofit organizations and causes.

The Innovation Fund

The Innovation Fund provides grants to projects focused on improving environmental health and climate resiliency in Berks County. Projects that include collaboration across sectors and/or opportunities for partnership building will be prioritized. 

Projects can include but are not limited to:

• New approaches to strengthen environmental health and climate resiliency, including research into new approaches.
• Small-scale implementation/construction of environmental best management practices (e.g. planting trees and native shrubs, community gardens, etc.)
• Support to obtain state or federal funding
• Education and outreach
• Project planning and development

Welcome Home Community Housing Fund 

This opportunity will be available only to developments already awarded CHF or HOME funds, with the goal of reducing planned 60% AMI units to 50% AMI units or below.

Clark County is making a BLM-owned site available for the development of affordable rental housing. 

Funding Goals and Scope

The goal of this funding round is to reduce the projected number of 60% AMI units (and 65% AMI units in limited instances) in the development pipeline to 50% AMI, and below, to meet the very low- and extremely low-income housing demands of the Las Vegas valley housing market. The COUNTY will determine eligibility for funding by population served and targeted income level(s), number of units impacted, financial capacity, the APPLICANTS ability to creatively maximize use of the additional CHF funds in combination with other funding sources, project readiness, and project feasibility. All project commitments outlined in the original application must remain, such as sustainability features, project amenities, unit amenities, overall design of the project, etc. All developments will be for affordable housing for households below 80% of AMI; any units above 80% will not be funded by CHF. Projects with market rate units will be required to show how those units will be funded on the FFS without using CHF funds. Though the COUNTY will provide a scoring preference for projects with higher numbers of units at or below 30% and 50% of AMI, the maximum amount of below 30% AMI, units allowed in any one project is 50% of the total. Projects that include between 10% and 50% of their units at 30% AMI or below may request additional CHF funds in order to reduce long-term debt and support higher operating costs; however, construction costs per unit must remain competitive. Projects with over 20% of the units at 30% AMI must have additional sources of long-term operating income to ensure that the project can sustain such deep rental subsidies. 

Illinois Department of Commerce and Economic Opportunity

The mission of the Illinois Department of Commerce and Economic Opportunity (DCEO) is to create equitable economic opportunities across the State of Illinois. By attracting and supporting major job creators, investing in communities, strengthening Illinois’ world-class workforce, fostering innovation, and ushering in the new clean energy economy, DCEO works to fortify Illinois’ reputation as a global economic powerhouse while ensuring Illinois is the best state to live, work and do business.

State Small Business Credit Initiative (SSBCI) Technical Assistance (TA) Grant Program – Loan TA Program – Region 4: North 

The Illinois Department of Commerce and Economic Opportunity (the “Department” or “DCEO”) is issuing this Notice of Funding Opportunity (“NOFO”) to seek application proposals from qualified technical assistance providers to deliver assistance to businesses owned by socially and economically disadvantaged individuals (SEDI1) or very small businesses (VSBs2) participating in, or seeking assistance from the state’s State Small Business Credit Initiative (SSBCI) funded programs. The technical assistance providers will provide support to eligible beneficiaries of the SSBCI Technical (TA) Grant Program located in Region 4: North. Specifically, the Illinois SSBCI Technical Assistance Grant Program will be delivered via two programs: the Venture Capital TA Program and the Loan TA Program.

The primary focus of this NOFO is the Loan TA Program which will assist eligible small businesses in applying for SSBCI funding and other government small business programs. The Loan TA Program will prioritize services that promote equitable economic opportunities for participating businesses across the state by enhancing their awareness and readiness to apply for and acquire capital, in addition to fostering entrepreneurial growth, and enhancing financial and business management skills.

The Venture Capital TA Program will be offered via a separate NOFO.

Native Forward awards are allocated based on the financial aid information provided by the institution’s Financial Aid Office. Awards can vary, ranging from $100 to $30,000 per academic year.

Native Forward Scholars Fund members of federally and state-recognized Tribes as well as first and second-generation descendants. However, Native Forward Scholars Fund scholarship opportunities have different Tribal eligibility requirements and can be determined by submitting a Tribal Eligibility Certificate.

Land Conservation and Indigenous Languages Scholarship

The purpose of the Land Conservation and Indigenous Languages Scholarship is to provide financial assistance to eligible American Indian and Alaska Native undergraduate and graduate students enrolled full-time at an accredited institution and pursuing degrees with a focus in Indigenous languages, natural resources, land management, and conservation or cultural preservation. 

This opportunity is a need-based award.

The Clifford Angell Memorial Scholarship, provided by the Elk Grove Regional Scholarship Foundation, supports students pursuing careers in Fire Science, Natural Resources, Conservation, or Wildlife Management. The scholarship is open to full-time and part-time students at four-year universities, community colleges, or vocational schools. Financial need is preferred but not mandatory. This initiative aims to empower local students in their educational and career pathways, fostering community engagement and support.

The Katma Award, established by the American Ornithological Society in 2003, honors innovative research that challenges existing theories in avian biology. This award encourages submissions of research articles, commentaries, or short communications published within the last two years. Nominees are expected to uphold high ethical standards, and the award includes a $2,500 prize and a certificate. Ideal submissions include papers authored by one or two researchers, with self-nominations also accepted.

The AOS-Sponsored Student Memberships provide one year of free membership to students globally interested in ornithology. Awardees gain full access to AOS membership benefits and are encouraged to participate in various opportunities, including the annual meeting and travel grants. This initiative aims to foster the next generation of ornithologists by supporting their academic and professional growth while upholding high ethical standards aligned with the AOS Code of Conduct.

The Florence Merriam Bailey Award, presented by the American Ornithological Society, honors outstanding articles published by early career members in AOS journals within the last two years. Awarded annually, it includes a $1,500 cash prize to the lead author. Papers recognized alternate between the journals 'Ornithology' and 'Ornithological Applications'. Nominees must adhere to high ethical standards as outlined in the AOS Code of Conduct.

The Frederick FEED Grant, administered by The Community Foundation of Frederick County, aims to enhance food equity and emergency distribution in the community. Open from December 1 to December 21, 2025, it supports existing food banks, pantries, and nonprofits in Frederick County. Grants can be utilized for expanding food distribution efforts and acquiring necessary equipment, thereby addressing critical food insecurity issues and fostering a healthier community for all.

The Miller Indigenous Economic Development Fellowship, established by the Native Forward Scholars Fund, provides financial assistance to American Indian and Alaska Native doctoral candidates engaged in economic research impacting Native communities. This fellowship supports costs associated with data collection, analysis, and travel. It aims to enhance the representation of Native scholars in economics, addressing the current underrepresentation in the field. Eligible candidates are encouraged to apply to further their research and contribute to their communities.

The Rosenberg Foundation is dedicated to dismantling systemic barriers to equity and opportunity for Californians. Through its grantmaking, it focuses on areas such as leadership development, criminal justice reform, and immigrant rights. The foundation supports innovative initiatives, including the 2022-2024 Leading Edge Fellows, who tackle pressing social issues. By fostering civic engagement, the foundation aims to empower underrepresented communities and ensure their voices are heard in policy discussions, ultimately striving for a more just society.

The SAF National Awards Program recognizes excellence in forestry through various awards, including the Award in Forest Science. This award acknowledges significant research contributions in quantitative, economic, managerial, and social sciences, promoting advancements in forestry. Recipients receive a $1,000 honorarium, a complimentary SAF convention registration, and travel expense support. Established in 1996, this award highlights the importance of innovative research that impacts both national and international forestry practices.

The SAF National Awards Program recognizes excellence in forestry through various awards, including the Barrington Moore Memorial Award in Biological Science. This award honors individuals for significant contributions to biological research that advances forestry practices. It includes a $1,000 honorarium, convention registration, and travel support. The award celebrates leaders in forest ecology, soil science, and other related fields, promoting innovation and collaboration in forestry research.