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Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.
33,000+
Available grants
$9.00B
Total funding
$6K
Median grant
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Arkansas Department of Agriculture
The Arkansas Department of Agriculture is dedicated to the development and implementation of policies and programs for Arkansas agriculture, forestry, and natural resources to keep its farmers and ranchers competitive in national and international markets while conserving natural resources and ensuring safe food, fiber, and forest products for the citizens of the state and nation.
The Arkansas Department of Agriculture works closely with Arkansas’s 75 conservation districts to protect and manage the state’s natural resources. We provide ongoing support through technical assistance, program coordination, training, and funding opportunities. Our goal is to strengthen each district’s capacity to deliver effective, locally led conservation efforts across the state.
Conservation District Grant Program
The Conservation District Grant Program provides funding to enhance the ability of conservation districts to carry out local conservation efforts. Through this program, the Arkansas Natural Resources Commission offers grant assistance for projects that promote resource protection, enhancement, or restoration.
Applications are reviewed for feasibility, practicability, and potential benefit to the applying district. After review, Department staff will rank each application and make funding recommendations to the Natural Resources Division Director. The director will then present recommended projects to the commission for final approval. Grant awards are made based on the anticipated conservation impact at the district, regional, or statewide level.
Dam Safety and Climate Resilience Local Assistance Program (CA)
The Dam Safety and Climate Resilience Local Assistance Program (DSCR) provides state funding for repairs, rehabilitation, enhancements, and other dam safety projects at existing state-jurisdictional dams and associated facilities that were in service prior to January 1, 2023. Established in 2023, the program has received a new allocation of $464 million in two rounds of funding through Proposition 4 (The Safe Drinking Water, Wildfire Prevention, Drought Preparedness, and Clean Air Bond Act of 2024). As a result of this new funding, the program requires new guidelines and a revised solicitation process..
Program Details
DSCR projects should provide some or all of the following public benefits.
They are listed below in order of priority:
DSCR projects eligible to receive funding under the program include the following:
Alkermes
At Alkermes, we apply our deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders, including addiction, serious mental illness and sleep disorders. With our portfolio of marketed medicines and investigational pipeline candidates, we seek to make a meaningful difference in the way people manage these chronic diseases. Our patient-inspired science, integrated research strategy, sophisticated development capabilities and specialized commercial infrastructure enable us to pursue the development and commercialization of innovative new medicines, including those for people with conditions that have traditionally been overlooked or stigmatized.
Our greatest strengths at Alkermes are our people and our inherent empathy for patients, families and caregivers. Neurological and psychiatric disorders strike people at the core of who they are and impact many facets of their lives. We work with urgency to develop new treatment options for people living with these conditions.
Pathways APN Research Awards
The Alkermes Pathways Advanced Practice Nurse (APN) Research Awards™ program is designed to empower the advanced practice nursing community by offering funding opportunities that recognize their vital role in evidence-based care and the advancement of mental health research.
The Alkermes Pathways APN Research Awards provide opportunities for individual grants of up to $10,000 per project for licensed psychiatric-mental health nurse practitioners who are actively engaged in clinical, academic, and/or community health settings and are committed to advancing research in schizophrenia or bipolar I disorder.
Ohio Water Development Authority
The Ohio Water Development Authority (OWDA) provides financial assistance for environmental infrastructure from the sale of municipal revenue bonds through loans to local governments in Ohio and from the issuance of industrial revenue bonds for qualified conduit projects in Ohio.
Emergency Relief Program
For What: Relief from Construction Repayments of Drinking Water, Wastewater, and Solid Waste Infrastructure
Purpose
For short-term relief from OWDA loan repayments so communities can use their repayment funds to recover from damages to their water, wastewater and solid waste infrastructure resulting from a federal or state declared emergency; OR
For construction of infrastructure to provide water and wastewater services to individual homes relocated due to mine subsidence.
Grant Amount
Disbursement
See the program guidlines for further information.
CDBG Construction Grants
Funding for all Community Development Block Grant programs is provided by the U.S. Department of Housing and Urban Development and administered by the Office of Community and Rural Affairs. The State of Indiana distributes CDBG funds to rural communities to support a range of projects, including infrastructure enhancement, downtown revitalization, improvements to public facilities, and economic development initiatives.
The state CDBG program offers competitive grants to units of local government to support rural areas.
Wastewater and Drinking Water (WDW) Program
Many communities in Indiana struggle with inadequate water supply and failing wastewater treatment. OCRA is committed to improving the quality of water and wastewater in Indiana and assisting in financing appropriate water and sewer infrastructure for communities and counties that have planned and set priorities for long-term development.
The goals of the Wastewater and Drinking Water (WDW) Program are to protect health and the environment, reduce utility rates for low- to moderate-income communities, and improve rural infrastructure for long-term sustainability and growth. General eligible activities include wastewater improvements such as collection lines or treatment plans, or drink water system improvements such as water towers or distribution.
Grant amounts for communities with existing systems are based on the current rates at the time of application. Grant amounts for communities constructing new systems will be based on a verified rate study included in a Preliminary Engineering Report (PER). The amount of CDBG funds granted will be based on a $5,000-cost-per-project beneficiary.
A local match of 20% of the total project cost will be required for consideration of funding.
General types of activities that are eligible for WDW funding:
Midwest Nursing Research Society (MNRS)
The MNRS originally began to provide a place for nurses to collaborate, and collaborate they did! Over time, the founding members began to realize the benefits of having an organization dedicated specifically to nursing research. With some careful attention and a lot of hard work, we have grown into the organization it is today. We're a society where scientists, innovators, and drivers of clinical practice across the career trajectory, come together to share ideas and grow our field through innovative research.
The mission of the MNRS is to generate knowledge, translate evidence into practice, and enhance careers through collaborative engagement, implementation, and dissemination among diverse scholars. Our Vision to be the premier society that advances science, fosters leadership, and drives dissemination to improve health equity for all people.
It is an honor to recognize the important contributions of our nursing colleagues. MNRS accepts nominations for our five very prestigious awards to selected members of the Society who have made significant and notable contributions to the field of nursing through research.
Distinguished Contribution Award
The purpose of the Distinguished Contribution Award is to recognize the scientific contribution of a member who has conducted or promoted research, which has enhanced the science and practice of nursing in the MNRS region.
Illinois Department of Commerce and Economic Opportunity
The mission of the Illinois Department of Commerce and Economic Opportunity (DCEO) is to create equitable economic opportunities across the State of Illinois. By attracting and supporting major job creators, investing in communities, strengthening Illinois’ world-class workforce, fostering innovation, and ushering in the new clean energy economy, DCEO works to fortify Illinois’ reputation as a global economic powerhouse while ensuring Illinois is the best state to live, work and do business.
Illinois Economic Empowerment Centers (EEC) Program
Short Description
Pursuant to 20 ILCS 605/605-503, the purpose of the EEC program shall be to provide training, support, resources and opportunities to minority group members, women, individuals with a disability, dislocated workers, veterans, and youth entrepreneurs.
Objective
The objective is to create an inclusive business ecosystem for communities that have traditionally faced systemic barriers to entry and growth, including those who have been justice-involved. The Department will award grants to eligible applicants who provide Socially and Economically Disadvantaged Individuals (SEDI) business owners, entrepreneurs and/or dislocated workers with technical assistance, training, and access to resources necessary for their start-ups or existing businesses.
Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.
Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?
Most grants are due in the first quarter.
What's the typical grant amount funded for Large Grants for Nonprofit Organizations?
Grants are most commonly $32,500.
Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.
Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.
Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.
To improve the chances of receiving large grants, nonprofits should:
Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.
Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.