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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,618 Results based on applied filters

Russell E. Train Fellowships: WWF Food Systems Fellowship

World Wildlife Fund
Private
Belize, Bhutan +32 more
Up to US $60,000
The WWF Food Systems Fellowship aims to promote environmental sustainability and equitable food distribution by supporting researchers and practitioners in graduate studies. It fosters understanding of food systems' complexities at local and global levels, addressing climate change, biodiversity, and human health. The fellowship encourages innovative solutions through diverse partnerships, focusing on governance, technology, and community engagement. Eligible applicants from specific countries can apply for funding to enhance their expertise and contribute to transformative food system practices.
Sustainability Food Access & Hunger Climate Change Resilience & Equity +1 more

Geoffrey Michael Chan Wing Au Scholarship Fund

Hawai'i Community Foundation
Private
Hawaii
Unspecified amount
The Geoffrey Michael Chan Wing Au Scholarship Fund, established in memory of a beloved science teacher and viola player, supports college juniors, seniors, and graduate students pursuing degrees in Science. Eligible applicants must be Hawaii residents, maintain a GPA of 3.0, and demonstrate financial need. Preference is given to students involved with the Hawai’i Youth Symphony or engaged in cancer research. This scholarship embodies a commitment to fostering academic excellence in the sciences.
Science Academic Scholarship Programs Cancer / Oncology +1 more

Marshall Community Foundation: Impact Grant

Marshall Community Foundation
Private
Calhoun County, Michigan
More than US $25,000

Marshall Community Foundation: Impact Grant

The Marshall Community Foundation reviews/awards grants quarterly and yearly based upon the size of the grant request. Grants are awarded to agencies across Calhoun County that benefit residents of the City of Marshall and surrounding townships. Grants are intended to be a flexible local funding opportunity that can respond to community needs.

Requests will only be considered for:

  • Capacity Building
  • New Major Projects
  • Challenge Grants
Community Services Youth Services Poverty Alleviation & Services +2 more

Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
United States
Up to US $1,750,000
The Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) award aims to assist federally recognized AI/AN Tribes, Tribal colleges and universities, and Tribal health organizations in creating or enhancing Institutional Review Boards (IRBs). This initiative is crucial for ensuring ethical research practices within Tribal communities, fostering cultural sensitivity in research, and protecting the rights of AI/AN participants. Applications must be submitted by 5:00 PM local time of the applicant organization.
Indigenous Health Systems Native American Services Indigenous Sovereignty & Rights +4 more

Electric School Bus Grant Program

State of New Jersey Department of Environmental Protection
State/Local Government
New Jersey
Up to US $350,000
The Electric School Bus Grant Program in New Jersey aims to transition the state's school bus fleets to electric, addressing the health impacts of fossil fuel-powered buses. With a funding limit of $15 million annually for three years, the program supports individual school districts and contractors in acquiring electric buses and charging infrastructure. Eligible applicants include school districts and bus contractors, with a focus on those serving Overburdened Communities. The program also offers reimbursement options for upfront costs of new buses and chargers.
Renewable/Sustainable Energy Public Transportation & Mass Transit Systems Emerging or Other Renewable Energy Sources +3 more

WMU Department of History: History Fellowship Award

Western Michigan University
Private
Michigan
US $1,000
The WMU Department of History offers a renewable $1,000 History Fellowship Award for newly admitted full-time freshman students majoring in history or related fields. Applicants must have a minimum 3.5 high school GPA and maintain the same GPA while enrolled. The fellowship is renewable for up to four years, ensuring continued support for students who maintain their academic standing. Applications are due by March 15, and underrepresented groups are particularly encouraged to apply.
Humanities & Social Science History Education +4 more

The Environmental Fellows Program

Harvard University
Private
Middlesex County, Massachusetts
Up to US $97,000
The Environmental Fellows Program at Harvard University provides recent PhD recipients the opportunity to engage in interdisciplinary research addressing complex environmental challenges. With a two-year fellowship, participants benefit from a competitive salary, health insurance, and allowances for relocation and professional expenses. This program aims to foster collaboration across diverse academic fields, enhancing innovative solutions to climate issues. Candidates with a wide range of academic backgrounds are encouraged to apply, ensuring a diverse cohort of scholars committed to impactful research.
Environment Climate Change Resilience & Equity Environmental Policy +1 more

Disputanta Volunteer Fire Department Joshua A. Culler Memorial Scholarship Endowment

John Randolph Foundation Inc
Private
Prince George County, Virginia, Southampton County, Virginia +1 more
Up to US $1,000
The Disputanta Volunteer Fire Department Joshua A. Culler Memorial Scholarship Endowment supports students from Prince George County pursuing higher education in medical fields or emergency services. Established in 2012 to honor Joshua A. Culler, a dedicated volunteer firefighter, the scholarship prioritizes applicants who volunteer with the department or are dependents of volunteers. Eligible students must demonstrate academic achievement and community involvement, ensuring a commitment to service and education.
Education - Higher Education Community Services Youth Services +3 more

Don and Bern Holcomb Memorial Scholarship

Cattaraugus Region Community Foundation
Private
United States
Unspecified amount

Don and Bern Holcomb Memorial Scholarship

This scholarship was created in memory of Don and Bern Holcomb and is for high school students from any school in Cattaraugus or Allegany county who plans to attend an accredited post-secondary institution, with a preference for a student majoring in an agricultural or conservation-related field or a female pursuing an engineering degree.

Education - Higher Education Engineering Farmland Preservation +1 more

Geneseo Foundation Grant

Geneseo Foundation
Private
Henry County, Illinois
Unspecified amount
The Geneseo Foundation Grant, established by George B. Dedrick in 1961, provides financial support to nonprofit organizations with 501(c)(3) status. The foundation aims to enhance the community of Geneseo, Illinois, by funding charitable, educational, and civic initiatives. Applications are reviewed monthly, with a commitment to allocate 5% of the foundation's annual market value. This grant serves as a vital resource for organizations that assist the sick, aged, and underprivileged, promoting both human knowledge and alleviating suffering.
Volunteerism & Philanthropy Civic Affairs Education +6 more

Sophia Smrz Memorial Scholarship

Marshfield Area Community Foundation Inc.
Private
United States
Unspecified amount

About Us

Marshfield Area Community Foundation, Inc. is a public, 501-C-3 charity. There are 30 community foundations in Wisconsin and more than 750 in the nation. The purpose of all community foundations is to accumulate charitable dollars that impact a specific geographic region in areas such as education, the arts, economic development, recreation, environmental protection, health care, and social services. They may be relatively small, as we are (assets of $14 million), or very large, as is the Greater Milwaukee Foundation (assets over $400 million).

Most people are familiar with private foundations, established by individuals, families, or corporations. Typically, in order to establish a private foundation, one has to have considerable wealth. You could say Community Foundations are much more democratic. We are, in a sense, an umbrella foundation containing many small foundations. We call those small foundations “funds.”

Marshfield Area Community Foundation Scholarships

The mission of the Marshfield Area Community Foundation is “Connecting people who care with causes that matter to enrich the quality of life in the Marshfield area”. Education is a valuable tool and a cause that matters to all of us. Through assisting students with financial support to receive an education, not only do students and the families of those students benefit, but also our community benefits, which further allows us to achieve our mission of enriching the quality of life in the Marshfield area.

Sophia Smrz Memorial Scholarship (2025)

Education - Higher Education Educational Access & Equity Science +3 more

PADDC Community Grants Program

Pennsylvania Developmental Disabilities Council (PADDC)
State/Local Government
Pennsylvania
Up to US $20,000

PADDC Community Grants Program

Our Community Grants Program brings together people, with and without disabilities, in a local community initiative to influence social change and improve the lives of everyone in the community. We support ideas that develop generic change, providing benefits to people with disabilities in settings that are the same as those available to community-at-large. If necessary, projects also change that generic community to meet the needs of people with disabilities, affirming the status of people with disabilities as full and equal members.

The Pennsylvania Developmental Disabilities Council (PADDC) uses the federal definition of developmental disabilities, as it appears in Developmental Disabilities Assistance and Bill of Rights Act of 2000 (The DD Act). This definition is based on substantial physical or mental impairment function in three or more major areas of life activity and the age of onset when the disability occurred.

Community Services Disability Care & Services Children With Disabilities +2 more

Genesis Mission Graduate Fellowship Pilot

United States Department of Energy (DOE)
Federal Government
American Samoa, Guam +4 more
US $12,000,000 - US $25,000,000
The Genesis Mission Graduate Fellowship Pilot aims to empower American scientists and engineers in the super intelligence (SI) revolution by inviting applications from U.S. higher education institutions. This initiative focuses on developing innovative doctoral training programs integrating SI with other scientific disciplines. Participants will gain valuable research experience through collaborations with DOE National Laboratories and industry, preparing them as the next generation of skilled Ph.D. scientists and engineers to tackle pressing national science and technology challenges.
Education - Higher Education Workforce Preparation & Job Readiness Emerging Technology Development +2 more

Missouri Building Entrepreneurial Capacity: Project Support Grant

Missouri Corporation For Science And Technology
Private
Missouri
US $150,000 - US $500,000
The Missouri Building Entrepreneurial Capacity (MOBEC) program, led by the Missouri Technology Corporation, aims to foster innovation and entrepreneurship. By providing targeted project support grants, MOBEC facilitates the growth of high-tech companies in Missouri. This initiative strengthens the state's innovation economy and supports entrepreneurs in commercializing new technologies. The funding is strictly allocated to specific projects, ensuring that resources are used effectively to enhance the entrepreneurial ecosystem and promote sustainable economic development.
Entrepreneurship Emerging Technology Development Economic Services & Development +2 more

Alfred P. Sloan Foundation Research Fellowship

Alfred P Sloan Foundation
Private
Canada, United States
US $75,000
The Alfred P. Sloan Foundation Research Fellowship supports innovative and fundamental research by early-career scientists across various fields. This prestigious two-year fellowship offers $75,000 in a lump sum, allowing recipients to allocate funds towards research-related expenses. Eligible candidates must hold a Ph.D. and be tenure-track faculty at U.S. or Canadian institutions. The fellowship aims to nurture the next generation of leaders in research and academia.
Evolutionary Biology Economics Mathematics +6 more

Armando "Frank" Quaglia Veteran's Scholarship

Grand Rapids Community Foundation
Private
United States
US $2,000 - US $5,000
The Armando "Frank" Quaglia Veteran's Scholarship, offered by the Grand Rapids Community Foundation, supports full-time graduate or upper-level undergraduate students from Kent or Ionia County pursuing healthcare or engineering degrees. With a minimum 3.0 GPA, preference is given to veterans and their families. This scholarship aims to eliminate barriers to education, fostering academic success and connecting students to opportunities in West Michigan's inclusive community.
Education - Higher Education College Success / Persistence Educational Access & Equity +3 more

Community Resilience Centers Round 2: Implementation Grant

California Strategic Growth Council
State/Local Government
California
US $1,000,000 - US $10,000,000

Community Resilience Centers Round 2

The California Strategic Growth Council (SGC) is pleased to announce the availability of approximately $55 million in funding from the Safe Drinking Water, Wildfire Prevention, Drought Preparedness, and Clean Air Bond Act of 2024 for Round 2 of the Community Resilience Centers (CRC) Program through this Notice of Funding Availability (NOFA). 

Program Summary

The CRC Program will offer Planning Grants and Implementation Grants. Unlike Round 1, the CRC Program will not offer a separate Project Development Grant type. Instead, Round 2’s Implementation Grant will offer a new, funded “Pre-Development Phase” that will support Lead Grantees’ project readiness before implementation. The Pre-Development Phase will last no more than one year from grant execution.

Implementation Grants

Grant Purpose

Implementation Grants will fund new construction and retrofits of facilities to serve as Community Resilience Centers, as well as programs and services that build overall community resilience.

Examples of Eligible Activities

Construction, retrofits, and other upgrades to the CRC Facility itself; Campus Amenity improvements; programs and services; community engagement.

Project Area

CRC applications must be community focused. All CRC Implementation Grant applicants are required to define a Project Area. The Project Area must encompass the physical location of the CRC Facility (the CRC Site), Campus Amenities connected to the CRC Facility, Partner Sites and any programs and services based out of the CRC Facility or Partner Sites.

Climate Change Resilience & Equity Disaster Preparedness Public Infrastructure +1 more

Cathern Tufts Memorial Scholarship

The Confederated Tribes of Siletz Indians
Federal Government
United States
Unspecified amount

Confederated Tribes of Siletz Indians

The Confederated Tribes of Siletz Indians is a sovereign nation and has three main branches of government – Judicial, Executive, and Legislative. One of our most important resources is our people.

Education

The Confederated Tribes of Siletz seeks to provide opportunities for Tribal members to reach potential, establish independence and improve quality of life through lifelong learning and education.

Cathern Tufts Memorial Scholarship

Cathern Tufts, affectionately known as “Cat” in the offices of the CTSI administrative offices and Tribal elder woodcuts, was the Tribal Attorney for fourteen and a half years until she passed in 2018 following a short illness. She was a Siletz Tribal member who graduated from Arizona State University School of Law. She served an internship in Washington D.C. prior to going to work as an attorney. Her parents and friends wished to honor her life and achievements through this memorial scholarship. This scholarship is for students in pre-law, law, or in a natural resource field.

Native American Services Law Education - Higher Education +1 more

Leo Zupin Memorial Scholarship

Grand Haven Area Community Foundation
Private
Michigan
Unspecified amount
The Leo Zupin Memorial Scholarship, offered by the Grand Haven Area Community Foundation, honors the legacy of a dedicated math educator. Open to Tri-Cities students, this scholarship emphasizes the importance of motivation over past academic performance. It seeks applicants facing adversity and pursuing vocational training or a degree in mathematics. Eligible candidates must submit transcripts and other required documents to apply. This scholarship serves as a tribute to Leo Zupin's commitment to education and the community.
Education - Higher Education College Success / Persistence Educational Access & Equity +3 more

Title V Senior Community Service Employment Program - Competitive

Illinois Department on Aging (IDoA)
Federal Government
Illinois
US $100,000 - US $3,030,248

About the Illinois Department on Aging

The mission of the Illinois Department on Aging is to serve and advocate for older Illinoisans and their caregivers by administering quality and culturally appropriate programs that promote partnerships and encourage independence, dignity, and quality of life.

Title V Senior Community Service Employment Program - Competitive

Description

The Senior Community Service Employment Program (SCSEP) is a program administered by the US Department of Labor (USDOL) and the Illinois Department on Aging (IDoA) that serves unemployed low-income persons who are 55 years of age and older and who have poor employment prospects by training them in part-time community service assignments and by assisting them in developing skills and experience to facilitate their transition to unsubsidized employment.

Placing older individuals in community service positions strengthens the ability of the individuals to become self-sufficient, provides needed support to organizations that benefit from increased civic engagement, and strengthens the communities that are served by such organizations.

Grantees will administer SCSEP in assigned geographic areas within Illinois per the requirements of the IDoA and USDOL.

Senior Services Employment Services Workforce Preparation & Job Readiness +1 more

AAAE Diversity, Equity & Inclusion Scholarship

American Association of Airport Executives
Association/Society
Canada, United States
Up to US $5,000
The AAAE Diversity, Equity & Inclusion Scholarship, provided by the AAAE Foundation, supports ethnic diversity students pursuing aviation studies in the U.S. or Canada. With two awards of $5,000 each, recipients are chosen based on their academic achievements, financial need, and community involvement. Eligible applicants include college juniors, seniors, or graduate students with a minimum GPA of 3.0. This scholarship aims to foster future leaders in the aviation industry, enhancing diversity and inclusion.
Diversity, Equity & Inclusion Aviation Asian / Pacific Island Culture & Heritage +3 more

Russell Family Foundation Grant

The Charles and Carolyn Russell Family Foundation
Private
Minnesota
US $1,000 - US $5,000
The Russell Family Foundation Grant, established in 2007 in Duluth, Minnesota, supports charitable causes in the areas of arts, education, environment, health, human services, public benefit, and religion. This private foundation awards grants exclusively to organizations that qualify under Section 501(c)(3) of the Internal Revenue Code, with a focus on those primarily located in Duluth. Their mission emphasizes fostering community welfare through diverse initiatives.
Art & Culture Education Environmental Conservation +8 more

The Arthur and Lila Weinberg Fellowship for Independent Researchers

The Newberry Library
Association/Society
Cook County, Illinois
US $3,000
The Arthur and Lila Weinberg Fellowship for Independent Researchers offers a $3,000 monthly stipend for one month, targeting writers, artists, and humanists. This fellowship encourages applicants working outside traditional academic settings, welcoming scholars of all nationalities. The Newberry Library provides a rich collection for research, focusing on projects that promote social justice. Ideal candidates include independent and early-career scholars, particularly those from the Chicago metropolitan area.
Performing Arts Visual Arts Humanities & Social Science +3 more

Major Capital Requests

McInerny Foundation
Private
Hawaii
More than US $500,000
The McInerny Foundation, one of Hawaii's largest charitable organizations, supports major capital requests for projects exceeding $500,000. These grants can fund equipment purchases, renovations, and environmental land protection. The foundation emphasizes collaboration, requiring organizations to secure 100% board financial contributions and 75% of their funding goal before applying. By fostering community involvement and ensuring financial accountability, the foundation aims to enhance the impact of its contributions across various sectors, including arts, education, and health.
Art & Culture Education Community Services +5 more

28-0343-04 State Agency Racial Profiling (RP) Program

Illinois Department of Transportation
State/Local Government
Illinois
US $1,500,000
The 28-0343-04 State Agency Racial Profiling Program aims to support the collection and evaluation of racial profiling data in Illinois. It focuses on enhancing agency compliance and reducing racial profiling in traffic stops through effective data management and outreach. Eligible applicants include state agencies with enforcement duties. The program seeks to promote transparency and public awareness regarding traffic stop statistics, ultimately contributing to safer interactions for all citizens on the road.
Public Transportation & Mass Transit Systems Police & Law Enforcement Automotive Safety +1 more

Aspire Grant Program

Conservation Action Research Network (CARN)
Private
Cameroon, Central African Republic +6 more
Up to US $5,000
The Aspire Grant Program, initiated by CARN, offers up to $5,000 USD in research grants for African graduate students and early career professionals. Focused on biodiversity, conservation, and environmental sustainability in the Congo Basin, it aims to support innovative research addressing critical ecological challenges. By fostering local expertise, this initiative encourages young researchers to remain in their home countries and contribute to conservation efforts amidst growing environmental threats.
Sustainability Environmental Conservation Ecology +1 more

Bradley-Turner Foundation Grant

Bradley-Turner Foundation Inc
Private
Chattahoochee County, Georgia, Harris County, Georgia +3 more
Approximately US $50,000
The Bradley-Turner Foundation Grant focuses on supporting initiatives in Columbus, Georgia, and the Chattahoochee Valley. With an average grant size of $50,000, it funds strategic capital campaigns, scholarships for students in need, and community initiatives tackling systemic challenges. The foundation prioritizes partnerships and considers requests tied to broader programs. However, it does not support annual funds, personal loans, or organizations lacking 501(c)3 status, aiming instead for impactful, one-time gifts.
Community Services Academic Scholarship Programs Public Infrastructure +4 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.