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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,618 Results based on applied filters

Women Giving Together Grants

Community Foundation of White County (CFWC)
Association/Society
White County, Indiana
Unspecified amount

About Us

Community Foundation of White County

Your community foundation is a philanthropic, nonprofit 501c3 organization that partners with visionary donors who believe that philanthropy has power to positively transform our White County community … forever.

To strengthen and transform our White County community by fostering charitable giving, philanthropic aspirations, and leadership.

Grants Available

Women Giving Together Grants

Grant are available to non-profit organizations serving White County women and children. This year's cycle will have an added focus on early childcare initiatives.

Women & Girl Services Child Welfare Services Art & Culture +5 more

St. Ignace Area Community Foundation: CTE Technical Scholarship

St. Ignace Area Community Foundation
Association/Society
United States
Unspecified amount

St. Ignace Area Community Foundation: CTE Technical Scholarship

The St. Ignace Community Fund annually awards scholarships assisting students with higher education, technical training, vocational training or retraining based largely on acknowledgement of student responsibility, community service, and civic involvement. These Scholarships are made possible through the generosity of donors to the various accounts within the St. Ignace Area Community Fund. Some accounts specifically are awarded to recognize higher education in the areas of special education, vocational/technical careers, teaching, law enforcement, and health care.

Vocational & Trade Education Nursing Special Needs Education +2 more

Les Paul Foundation Grant

Les Paul Foundation
Private
United States
US $1,500 - US $2,000
The Les Paul Foundation Grant supports innovative music education and medical research related to hearing loss. Eligible organizations must be U.S.-based public charities under 501(c)(3) and avoid religious, political, labor, or business affiliations. The foundation prioritizes projects that enhance music production, performance, and STEM/STEAM initiatives, particularly those benefiting individuals in challenging situations. Proposals must detail how they will share Les Paul's legacy in their work.
Music Education STEM / STEAM Education Hearing Disorders & Audiology

Environmental Initiative- Planning Grants

Laura Jane Musser Fund
Private
Alleghany County, North Carolina, Ashe County, North Carolina +25 more
Up to US $8,000
The Environmental Initiative Grant Program by the Laura Jane Musser Fund aims to support public and nonprofit entities in enhancing the ecological integrity of open spaces. It promotes community involvement in planning and implementing projects that improve quality of life and public health while protecting ecosystems. Grants range from $8,000 for planning to $35,000 for implementation, targeting projects in specific states, fostering sustainability, and ensuring active local participation.
Habitat & Ecosystem Restoration Land / Habitat Conservation Parks & Public Spaces

Hutsell, Alan Scholarship Fund

Noble County Community Foundation
Private
United States
US $500

Hutsell, Alan Scholarship Fund

For a high school senior from Central Noble, East Noble, Wawasee, West Noble or homeschool (homeschooled student must live in Noble County) who will be pursuing advanced education in emergency services involving fire, police, criminal justice and/or EMS.

Awards Per Year:

  • 1 scholarship

Applicant High School:

  • Central Noble, East Noble, Homeschooled, Wawasee, West Noble

Colleges:

  • Any accredited college or university

Areas of Study:

  • Criminal Justice, Emergency Medical Services, Emergency Services, Emergency services involving fire, police, criminal justice and/or EMS.

Education - Higher Education Emergency Medical Care & Services Criminal Justice System Reform +1 more

Modesto Rotary Club Foundation Community Grant

Modesto Rotary Club Foundation
Private
Stanislaus County, California
Unspecified amount

The mission of The Modesto Rotary Club Foundation (MRCF) is to support local organizations and projects through charitable contributions. 

Grants

The Modesto Rotary Club Foundation’s aim is to help organizations stretch and have bigger impact in Modesto.

The Modesto Rotary Club Foundation will support game-changing work across all program areas, and we especially encourage initiatives that support:

  • Health and wellness
  • Youth enrichment
  • Community beautification
  • Assist vulnerable families

Successful applications will demonstrate community need, and yield tangible and measurable results. Funds are available for program development/expansion, innovation, technology and equipment. 

Award amounts will be based on:

  • Proposed project budget
  • Scope of project
  • Capacity of organization to successfully execute the project

Wellness & Healthy Living Health Disparities & Social Determinants of Health Youth Development & Leadership +2 more

Scotiabank Corporate Giving Program: ScotiaRISE

Scotiabank
Corporate
Antigua and Barbuda, Aruba +29 more
Unspecified amount
The ScotiaRISE initiative by Scotiabank aims to foster economic resilience among disadvantaged groups over ten years, with a budget of $500 million. By focusing on enhancing educational opportunities, facilitating employment for newcomers, and removing barriers to career advancement, ScotiaRISE seeks to create a more inclusive society. This program highlights the importance of collective efforts in supporting individuals and communities to thrive, ensuring everyone has the chance to rise above challenges and contribute positively to their environments.
Economic Services & Development Education - High School Educational Access & Equity +1 more

Clinical Repurposing Research to Impact Veterans/Military

Cures Within Reach
Private
United States
Up to US $75,000

Cures Within Reach

Cures Within Reach is the philanthropic leader in drug, device and nutraceutical repurposing research, which has the potential to transform the lives of patients with unsolved diseases by delivering treatments that can be used in the near-term. Our focus: we find and fund proof-of-concept clinical trials that, once successful, de-risk and catalyze follow-on funding, building the clinical evidence required for regulatory approval or to support off-label use by patients everywhere.

Clinical Repurposing Research to Impact US Veterans/Military

This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from US-based research institutions using already approved treatments to address unmet and high-priority medical needs of US veterans and/or active US military, such as mental health, post-traumatic stress disorder (PTSD) and brain injuries. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials. Eligible trials may be conducted at accredited US-based academic, nonprofit and governmental research institutions and/or health systems involved with medical research, including Veterans Administration (VA) health systems and hospitals. 

Repurposed therapies must be approved and/or generally recognized as safe for human use by some regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and may include drugs, devices, nutraceuticals or diagnostics, as well as combination therapies. These repurposed therapies must be tested in a new indication for which they are not already approved or used widely in clinical practice as standard of care. Repurposed therapies also may be added to current standard of care to improve patient outcomes and/or quality of life.

Mental Health & Psychiatric Diseases Post-Traumatic Stress Disorder Brain Injuries +2 more

PLTW Engineering - New Program (Intel Foundation)

Project Lead the Way inc.
Private
Arizona, New Mexico +1 more
US $20,000

Each PLTW Engineering course engages students in interdisciplinary activities like working with a client to design a home, programming electronic devices or robotic arms, or exploring algae as a biofuel source. These activities not only build knowledge and skills in engineering, but also empower students to develop essential skills such as problem solving, critical and creative thinking, communication, collaboration, and perseverance.

Through this partnership, Intel Foundation has committed funds to support PLTW grants to schools interested in starting or expanding PLTW programs beginning in the 2027-2028 academic year.

Program Requirements: 

  • Grantee must offer at least one PLTW Engineering course in the 2027-2028 academic year and must offer one additional course each academic year of the grant period (two different courses in two years). 
  • Schools may implement any PLTW Engineering courses of their choosing. 
  • Grantee must complete two years of Grant reporting. 

Grant Award and Distribution Schedule:

  • Total Award: $40,000
    • 2027-2028: $20,000
    • 2028-2029: $20,000

Workforce Preparation & Job Readiness Career / College Preparation STEM / STEAM Education

Black Mountain-Swannanoa Valley Endowment Fund

The Community Foundation of Western North Carolina
Private
Buncombe County, North Carolina
US $2,500 - US $10,000
The Black Mountain-Swannanoa Valley Endowment Fund supports charitable organizations in the Swannanoa Valley, focusing on health, education, and wellness. Grants range from $2,500 to $10,000 for innovative projects and programs. Eligible organizations include 501(c)(3) entities and governmental bodies within the Owen School District. The Fund emphasizes projects that can be completed within a year but prioritizes requests for ongoing support less favorably. Endorsements are required if another organization benefits.
Health & Medicine Education Art & Culture +3 more

PLTW Biomedical Science - New Program (Launching STEM Atlanta)

Project Lead the Way inc.
Private
Cherokee County, Georgia, Clayton County, Georgia +8 more
US $35,000

About PLTW Biomedical Science

PLTW Biomedical Science students have experience with state-of-the-art tools and techniques that are used by professionals in hospitals and labs every day.  By immersing students in activities like practicing suturing and constructing body structures from clay, PLTW Biomedical Science empowers students to build knowledge and skills in biomedical science, as well as in-demand, transportable skills like problem solving, critical and creative thinking, communication, and collaboration.Public schools, including charter schools, that meet the 10-county geographic requirement that do not yet offer PLTW Biomedical Science are eligible for consideration to support program implementation. PLTW will disburse grant funds over two years and require two years of reporting from awarded schools. Program Requirements

  • Grantee must offer at least one PLTW Biomedical Science course in the 2027-2028 academic year and must offer one additional course in the 2028-2029 academic year (two different courses in two years)
  • Grantee may implement any PLTW Biomedical Science courses of their choosing.

Grant Award and Distribution Schedule:

  • Total Award: $35,000
    • 2027-2028: $20,000
    • 2028-2029: $15,000
Biomedical informatics Career / College Preparation Workforce Preparation & Job Readiness

Collective Impact Grant

Parkview Legacy Foundation
Private
Riverside County, California
Approximately US $100,000

Parkview Legacy Foundation

The Parkview Legacy Foundation was created in July of 2019 by the sale of Parkview Community Hospital Medical Center (a non-profit hospital) to AHMC (a for-profit hospital group). With the sale, the State of California required that the proceeds of the non-profit hospital be put to use for the benefit of the community through the creation of non-profit public charity or private foundation. The Parkview Legacy Foundation is the result of that transaction, and Parkview Legacy Foundation now exists as an independent Public Charity serving the Riverside region. With the funds endowed to the foundation, we are honored to invest back into the local community with a broader scope of ensuring the equitable probability of wellness through social determinants of health.

Parkview Legacy Foundation is committed to support organizations, collaborations, and initiatives that directly address the root causes which negatively affect the four focus areas of housing stability, social mobility, whole health accessibility, and integrated solutions, and therefore, prevent residents of the Inland Region from achieving wellness and stability. 

Collective Impact Grant

Parkview Legacy Foundation’s Impact Grants Program is driven by our core values and intended to support organizations seeking to make transformational progress in addressing needs and seizing opportunities in our four focus areas throughout the Riverside region.   

Collective Impact funding is intended to support the advancement of efforts toward specific and stated objectives (goals, outcomes, and/or impacts) being carried forth by strategically coordinated and operated multi-sector collaborations and initiatives involving multiple organizations and/or institutions. Examples of ways the Collective Impact Grant may be used include:

  • funding the operations of a backbone organization for the effort,
  • providing participation funding to the participating organizations to help sustain the effort, and
  • paying consultants or partner organizations to accomplish specific tasks on behalf of the effort.  
Health Care Access & Delivery Wellness & Healthy Living Equitable & Affordable Housing +1 more

MFi Legacy Fund grant

Medfield Foundation Inc.
Private
Norfolk County, Massachusetts
Unspecified amount
The MFi Legacy Fund grant, managed by the Medfield Foundation Inc., aims to enrich the lives of Medfield residents through community initiatives. Eligible applicants must be registered non-profits or associated with town departments, focusing on programs that exclusively serve Medfield. The grant process involves submitting an application to participate in the Pitch It! event, where successful applicants present their projects. Grants are awarded based on these presentations, fostering a stronger community through collaborative efforts.
Art & Culture Youth Services Recreation +7 more

Quinnipiac River Fund Grants

Community Foundation for Greater New Haven
Private
Fairfield County, Connecticut, New Haven County, Connecticut
Unspecified amount
The Quinnipiac River Fund Grants, founded in 1990, aim to enhance the environmental quality of the Quinnipiac River and New Haven Harbor. Annually, over $100,000 is allocated to projects focusing on pollution reduction, ecological research, public education, and habitat restoration. Eligible applicants include tax-exempt organizations and their fiscal agents. Priority is given to local nonprofits. This fund supports initiatives that significantly improve the health of the river and its surrounding watersheds.
Ecology Freshwater Conservation Environmental Contamination & Pollution +1 more

New Jersey Competitive Integrated Employment (CIE)

New Jersey Department of Labor and Workforce Development
State/Local Government
New Jersey
Approximately US $260,005

Department of Labor and Workforce Development

The New Jersey Department of Labor and Workforce Development is dedicated to protecting our workforce, strengthening our businesses, and promoting the dignity of work.

The Division of Workforce Development is responsible for New Jersey’s workforce services, including vocational rehabilitation services, veteran’s services, and more. The division oversees the One-Stop Career Centers throughout the state, which offer a variety of programs and services to help employers meet their need to secure talented workers.

New Jersey Competitive Integrated Employment (CIE): Implementation & System Advancement (Phase II)

Grant Overview

Grant funds will be awarded to successful applicants who were previously awarded NJCIE Pilot Program grant funds from the NJCIE Pilot Program launched in 2024. Building on the success of the initial NJCIE Pilot launched in 2024, this next phase focuses on advancing participant outcomes and strengthening employer partnerships through more structured, outcome-driven service delivery models. This Phase II opportunity supports community rehabilitation providers in refining and scaling strategies that connect career pathway development, industry-recognized credential attainment, and competitive integrated employment. The program places an increased emphasis on measurable outcomes, including retention, wage progression, and long-term employment stability, while continuing to support the transition toward fully integrated employment opportunities statewide.

The purpose of the NJCIE program is to provide an opportunity for community rehabilitation providers to strengthen organizational capacity and pilot innovative employment and training services for people with disabilities that are intended to lead to competitive integrated employment. 

Disability Care & Services Workforce Preparation & Job Readiness Employment Services

RFP: RHTP Healthcare Workforce Retention Program

Minnesota Department of Health
State/Local Government
Minnesota
US $150,000 - US $183,000

Minnesota Department of Health

Mission: Protecting, maintaining and improving the health of all Minnesotans.

Vision: The vision of MDH is for health equity in Minnesota, where all communities are thriving and all people have what they need to be healthy.

Rural Health Transformation Program: Healthcare Workforce Retention Program

Program Description

Minnesota’s RHTP covers a broad range of initiatives designed to transform the state of the rural health system by improving health outcomes and access to care for rural Minnesotans, strengthening partnerships between providers to expand service delivery in rural communities, and stabilizing rural provider financial health through strategic investments.

This RFP seeks proposals to understand systemic factors leading to provider/clinician burnout; develop, pilot and scale responsive solutions to decrease burnout; and link the solutions to improved working conditions to improvements in provider retention and patient experience and/or outcomes. 

Health Disparities & Social Determinants of Health Rural Health Care Workers’ Rights +1 more

Chisholm Community Foundation Grants

The Saint Paul & Minnesota Foundation
Private
St. Louis County, Minnesota
Unspecified amount
The Chisholm Community Foundation Grants support innovative projects that benefit the Chisholm and Balkan communities in various sectors, including arts, education, and environmental conservation. The foundation prioritizes projects with matching funds, encourages volunteer involvement, and seeks initiatives that demonstrate new solutions to community challenges. Eligibility is limited to 501(c)(3) nonprofits and government agencies, while restrictions apply to operating expenses, endowments, and individual grants.
Environmental Stewardship Art & Culture Economic Services & Development +3 more

CLCF Opportunity Grant

Central Louisiana Community Foundation
Private
Allen Parish, Louisiana, Avoyelles Parish, Louisiana +10 more
US $250 - US $2,000
The CLCF Opportunity Grant supports eligible organizations in Central Louisiana with grants ranging from $250 to $2,000. Applications are accepted quarterly, focusing on areas such as literacy, arts, culture, and community development. The program aims to enhance the quality of life by connecting local donors with projects they care about, promoting charitable giving, and addressing community needs effectively.
Literacy Art & Culture Historic Preservation +3 more

National Parks Business Plan Internship

US Department of the Interior: National Park Service (NPS)
Federal Government
American Samoa, Guam +4 more
Up to US $1,700,000
The National Parks Business Plan Internship aims to enhance the operational health of national parks through a graduate-level program that trains students in business management and NPS operations. Participants will engage in substantive analysis, gain insights into park management, and promote federal careers in conservation. This initiative seeks to involve underrepresented graduate students from disciplines such as business administration and public policy, fostering a commitment to stewardship of public lands.
Education - Higher Education Environmental Education Workforce Preparation & Job Readiness +1 more

Seymour Siegel Youth Achievement Award

Jewish Community Foundation
Private
United States
Unspecified amount
The Seymour Siegel Youth Achievement Award, offered by the Jewish Community Foundation, provides financial support for high school students pursuing post-secondary education or vocational training. Open to applicants of the Jewish faith, this award prioritizes those from single-parent households, orphans, or foster children. Interested candidates must submit a personal narrative detailing their qualifications. The foundation, established in 1979, is a leading community resource in South Jersey, managing over $35 million in assets.
Education - Higher Education Education - High School Academic Scholarship Programs +2 more

Howe Foundation Grant

Howe Foundation 45871100
Private
United States
Approximately US $5,000
The Howe Foundation, established by Thomas E. Howe in Clark County, Nevada, supports U.S. charitable organizations focused on education, medical advancements, and game hunters associations. Grants are administered by Wells Fargo Bank, with applications reviewed annually in September. Eligible organizations must be 501(c)(3) exempt under the Internal Revenue Code, ensuring support for meaningful community initiatives.
Education Health & Medicine Wildlife Management +1 more

Educational Funding

Syndax Pharmaceuticals, Inc
Corporate
United States
Unspecified amount

Syndax Pharmaceuticals, Inc.

At Syndax, we are determined to realize a future in which people with cancer live longer and better than ever before. We believe that it takes a community to build a great medicine, and that is why we are working to set the new standard for developing medicines in the field of oncology – one that revolves around collaboration, shared learning, and excellence.

Syndax’s mission is to obtain regulatory approval and commercialize drugs that extend and improve the lives of cancer patients by drawing on the newest scientific research and advances, collaborating with determined problem solvers, and identifying value in overlooked aspects of science.

Educational Funding

At Syndax, we are committed to the goal of supporting objective, balanced and scientifically rigorous education that furthers improvements in science, medicine, and patient care. We accomplish this goal, in part, by providing grants for independent medical education (IME) programs. These can include live, online, and/or enduring programs that educate healthcare providers (HCPs), patients, or caregivers. Programs that are funded via Syndax medical education grants must be primarily dedicated, in both effort and time, to medical, health or scientific topics that are objective, balanced, unbiased, and scientifically rigorous. Medical education grants must never be made with the intent to directly or indirectly reward, influence or encourage the recipient to prescribe, purchase, sell or arrange for any Syndax product.

Cancer / Oncology Medical Education & Professional Training Leukemia

ESHPF Disaster Relief Assistance Grant Program

The Virginia Department of Historic Resources
State/Local Government
Albemarle County, Virginia, Appomattox County, Virginia +35 more
Unspecified amount
The ESHPF Disaster Relief Assistance Grant Program, administered by the Virginia Department of Historic Resources, has received $2,000,000 from the NPS to document historic resources in areas affected by Hurricane Helene. This program aims to support community-driven efforts for surveying architectural and archaeological sites in 37 localities across Virginia. Eligible projects may include preservation planning and nominations for the National Register of Historic Places, ensuring the protection and recognition of Virginia's rich cultural heritage.
Landscape Architecture Land / Habitat Conservation Historic Preservation

OAHSTRIDES Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $250 - US $5,000

About the Hartford Foundation for Public Giving

Greater Hartford Gives Foundation, formerly known as the Hartford Foundation for Public Giving, is the largest community foundation in Connecticut. We serve 800,000 residents across 29 towns that make up Greater Hartford. Community is at the heart of what we do. We want to make this region a more inclusive and equitable place to live, work, and start a family.

OAHSTRIDES Fund

The Greater Hartford Gives Foundation is pleased to announce that it is accepting applications for grants through the OAHSTRIDES Fund. OAHSTRIDES is the philanthropic arm of Orthopedic Associates of Hartford, PC. They work with under-resourced populations in the Greater Hartford Community to provide the support needed to build essential life skills and live healthier lifestyles. Their Mission is to improve physical, emotional, and mental health with an emphasis on movement and mobility.

For the 2026 grant cycle, OAHSTRIDES is focused on supporting veterans in the Greater Hartford community through adaptive physical activity, mental wellness initiatives, and opportunities for meaningful community connection and reintegration. We recognize that many veterans carry visible and invisible impacts of service, including physical injuries, chronic pain, mobility challenges, post-service transition difficulties, and social isolation.

Through this funding opportunity, OAHSTRIDES seeks to partner with organizations that honor veterans’ experiences and are committed to empowering them through movement-based and wellness-centered programs. We aim to support initiatives that foster resilience, restore confidence and connection, and promote lifelong health and well-being for those who have served.

Programmatic and project-specific requests are strongly encouraged.

Military & Veterans Services Wellness & Healthy Living Physical Therapy +2 more

International Development & Education Award

Conquer Cancer Foundation
Corporate
Afghanistan, Albania +138 more
Unspecified amount
The International Development and Education Award (IDEA) supports early-career oncologists in low- and middle-income countries, enhancing their expertise through mentorship and participation in the ASCO Annual Meeting. Recipients benefit from long-term professional relationships and access to resources such as the Journal of Clinical Oncology. Additionally, the IDEA-PC program focuses on medical education in palliative care, fostering knowledge sharing and collaboration to improve cancer care in their home countries.
Cancer / Oncology Palliative Care Medical Education & Professional Training

Utah Outdoor Recreation Grant (UORG): Mini-Grant

Utah Division of Outdoor Recreation
State/Local Government
Utah
US $5,000 - US $30,000

Utah Outdoor Recreation Grant

The Utah Outdoor Recreation Grant (UORG) is for new outdoor recreation infrastructure projects and helps communities build recreation amenities that support local economic development, tourism, and quality of life improvements for Utah’s residents.

Introduction

The Utah Division of Outdoor Recreation (DOR) is committed to ensuring every Utahn can live a healthy and active lifestyle through outdoor recreation and access to natural space. The DOR focuses on four key areas: expanding recreational access, promoting safety and education, ensuring responsible stewardship and sustainable visitation, and driving economic growth through outdoor recreation.

With our grant programs, we support local communities in achieving these goals and are thrilled to offer five grants under the Utah Outdoor Recreation Grant (UORG) Program in 2026.

Mini Grant

Ideal for smaller projects

Outdoor Recreation Tourism Outdoor Equity +2 more

NAAF Grant - General

Native American Agriculture Fund
Private
United States
Unspecified amount
The Native American Agriculture Fund (NAAF) offers grants to support Native farmers and ranchers through business assistance, agricultural education, technical support, and advocacy services. Established from the Keepseagle v. Vilsack settlement, NAAF is committed to providing essential resources to eligible organizations, including 501(c)(3) nonprofits, educational institutions, and tribal governments. Special focuses include inflation assistance and market access, ensuring a holistic approach to agricultural support.
Livestock & Ranching Farms & Farming Indigenous Sovereignty & Rights +1 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.