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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,618 Results based on applied filters

Beavers Heavy Construction Scholarship

Montana State University
State/Local Government
Gallatin County, Montana
Unspecified amount
The Beavers Heavy Construction Scholarship at Montana State University provides financial support for students pursuing a degree in Civil Engineering or Construction Engineering Technology. This scholarship aims to assist those demonstrating outstanding academic records and potential for success in the heavy construction industry. Awards vary, making this opportunity accessible to a wide range of applicants. Students are encouraged to apply and benefit from the resources available at Montana State University to further their educational goals.
Engineering Civil Engineering Academic Scholarship Programs

Jean Wood Preston Grant

First Baptist Church Of Lincoln Foundation Inc
Private
Middlesex County, Massachusetts
Up to US $25,000

About us

With roots in the Unitarian and Congregational traditions, the First Parish in Lincoln (FPL) celebrates many theologies and spiritual beliefs. We advocate inclusion and respect for all people. We gather each Sunday for worship at 10 a.m. During Sunday worship, we offer church school for school-aged children as well as nursery care for toddlers and preschoolers. Following worship, we come together at “coffee hour,” an ideal time to meet the minister and members of the congregation, as well as get information about the church.

Throughout the year, we rejoice in marking the changing seasons. Our celebrations range from a water communion welcoming all in September; winter concerts, solstice and Christmas Eve services, and children’s pageant in December; to the annual publication of a Lenten booklet filled with personal submissions from parishioners and the celebration of Easter in the spring.

The community of First Parish draws many members. Whether encountering friends and neighbors on Sunday, volunteering in the church school, or working on committees and service projects, our members and friends embrace the collective whole, recognizing that we are not alone, that we are part of a strong and supportive community.

Parishioners are instrumental in helping to run the church. While there is a core staff in place to provide the essentials, our members and friends come together to support the church in whatever way they are able. In addition to financial support, this can include arranging flowers for the pulpit, serving on a committee, teaching Sunday School, or helping with a special event.

Jean Wood Preston Grant

The First Parish in Lincoln has the honor of choosing the recipients of annual grants from this fund established by a longtime member of our community. In recent years the grants have been as much as $25,000, and may be used for one-time capital projects or Transformative Innovation initiatives.

Community Services Economic Services & Development Community Development & Revitalization

The Nature Awards Inspiring Women in Science: Scientific Achievement

Springer Nature Limited
Corporate
Afghanistan, Algeria +95 more
Up to US $50,000
The Nature Awards for Inspiring Women in Science celebrate outstanding contributions by women in STEM fields. These awards recognize early-career female researchers who demonstrate exceptional achievements, face challenges, and inspire the next generation through outreach. Winners receive prizes totaling $50,000, mentorship opportunities, and invitations to prestigious ceremonies. This initiative promotes inclusivity and aims to enhance the representation of women in science, thereby supporting a diverse and equitable scientific community.
Engineering Mathematics Science +2 more

Community Planning Technical Assistance (CPTA) Grant

Florida Commerce
State/Local Government
Florida
Unspecified amount

CPTA Grant Program

FloridaCommerce is now accepting grant requests for the Community Planning Technical Assistance (CPTA) Grant Program for State Fiscal Year (SFY) 2026-2027. CPTA grants provide local governments located in Rural Areas of Opportunity (RAOs) and/or rural communities, counties, municipalities and regional planning councils the opportunity to create innovative plans and development strategies to promote a diverse economy, and meet statutory requirements for planning, while also protecting environmentally sensitive areas.

Technical assistance and training will be available to rural local governments awardees to help assist them in best practices relating to comprehensive planning, economic development and land development, as well as strategies to address management and administrative capacity challenges unique to rural local governments. Preference shall also be given to local governments located in a RAO. Understanding that many Florida communities have been impacted by hurricanes, CPTA grants may also be used to assist with disaster recovery, resiliency and economic development planning. 

Project Types

Projects should relate to community planning and economic development strategies that implement the requirements in the Community Planning Act. FloridaCommerce also encourages rural communities to apply for projects related to planning for disaster recovery and community resiliency, especially related to flooding, and that meet the requirements in Chapter 163.3178(2)(f), Florida Statutes. Applicants are encouraged to seek funding for innovative, creative or unique approaches to planning, development and infrastructure in their community.

Urban Planning Emerging Technology Development Technology Access & Digital Literacy

Engineering (ENG): Civil, Mechanical and Manufacturing Innovation (CMMI)

National Science Foundation (NSF)
Federal Government
American Samoa, Guam +4 more
Unspecified amount
The National Science Foundation (NSF) is offering funding through the Engineering (ENG) program, focusing on foundational research in civil, mechanical, and manufacturing innovation. Key areas include advanced manufacturing systems, civil infrastructure, and intelligent dynamic systems. The NSF ENG encourages innovative and transformative proposals that may not require immediate commercial outcomes. Award sizes and durations will vary based on budget availability, aiming to support long-term research advancements.
Engineering Manufacturing Engineering Mechanical Engineering

Froderman Foundation Grant

Froderman Foundation
Corporate
Indiana
Unspecified amount
The Froderman Foundation Grant, established in 1961 by Mr. and Mrs. G. Harvey Froderman, supports qualified applicants focusing on religious, educational, medical, and charitable initiatives. The foundation promotes equity by considering applications without regard to race, creed, or color. Applicants must provide proof of 501(C)3 status and detailed plans for fund utilization, as general operating budgets are not typically funded. This grant aims to enhance impactful community projects.
Education Health & Medicine Community Services +1 more

Teens Active in Grantmaking (TAG)

Community Foundation of the Quincy Area
Private
Adams County, Illinois
Unspecified amount

Community Foundation of the Quincy Area

My Community Foundation (also known as The Community Foundation Serving West Central Illinois & Northeast Missouri) is a tax-exempt 501(c)(3) nonprofit organization dedicated to improving quality of life in the communities it serves by connecting compassionate donors with meaningful causes. The foundation works with individuals, families, businesses, and nonprofit partners to gather charitable contributions, grow those funds through professional investment strategies, and grant the earnings in ways that address local needs now and into the future. It builds and manages permanent endowments tailored to donors’ goals, ensuring their philanthropic visions—whether honoring a loved one, establishing a legacy, or supporting community needs—are realized. Serving a 12-county region across West Central Illinois and Northeast Missouri, the foundation acts as a steward of charitable assets, helping donors make a lasting impact through customized giving opportunities, community grants, and strategic support for nonprofit organizations.

Teens Active in Grantmaking (TAG)

TAG (Teens Active in Grantmaking) is a chance for high school students in Quincy to make real change in their community. From September to May, TAG members meet monthly to explore the world of community leadership, philanthropy, and civic engagement. Through hands-on learning, guest speakers, and team collaboration, members gain a deeper understanding of local issues and how nonprofits make a difference.

Whether you're passionate about mental health, food access, education, or creating more opportunities for youth, TAG gives you the tools (and trust!) to turn ideas into impact.

Community Services Community Development & Revitalization Youth Services

Local Share Account (LSA) – Washington County

Pennsylvania Department of Community and Economic Development
State/Local Government
Pennsylvania
Unspecified amount
The Local Share Account (LSA) funding program in Washington County, administered by the Pennsylvania Department of Community and Economic Development, aims to enhance community and economic well-being. Established by the PA Race Horse Development and Gaming Act, this program allocates portions of local share assessments from licensed gaming facilities to support various local initiatives. Interested applicants should contact the Redevelopment Authority of Washington County for further details on the application process.
Economic Services & Development Community Development & Revitalization

Pennsylvania Strategic Investments to Enhance Sites Program (PA SITES)

Pennsylvania Department of Community and Economic Development
State/Local Government
Pennsylvania
Up to US $250,000
The Pennsylvania Strategic Investments to Enhance Sites Program (PA SITES) aims to provide grants and loans for developing competitive sites, enabling businesses to relocate or expand within the Commonwealth. With a focus on planning and construction grants, the program helps cover development risks and supports strategic investments that enhance site viability. Applications are accepted year-round and are reviewed quarterly, ensuring timely funding for eligible projects that promote economic growth across Pennsylvania.
Economic Services & Development Community Development & Revitalization

Susan Yaw Memorial Scholarship

Community Foundation of North Central Washington
Private
Chelan County, Washington, Douglas County, Washington +2 more
Unspecified amount
The Susan Yaw Memorial Scholarship, established by the North Central Washington UniServ Council, honors the legacy of Susan Yaw, a dedicated advocate for education. This scholarship supports education professionals in Chelan, Douglas, Grant, or Okanogan Counties seeking further education or professional development, including NBCT and Master’s programs. Recipients may renew after three years, encouraging ongoing growth in their educational careers. The scholarship reflects a commitment to enhancing educational opportunities in the local community.
Education Academic Scholarship Programs

Partnership with Common Fund Data Ecosystem Resources

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
US $500,000 - US $1,200,000
The NIH Common Fund Data Ecosystem aims to enhance the reusability of biomedical data through collaboration between Common Fund programs and external data resources. This funding opportunity encourages projects that connect various biomedical data ecosystems, including the HEAL Data Ecosystem and the BRAIN Initiative. By fostering partnerships, the initiative seeks to improve the accessibility and interoperability of valuable datasets, ultimately advancing research efforts. Note that clinical trials are excluded from this funding opportunity.
Health & Medicine Biomedical informatics

Clinical & Translational Science Award TL1 Postdoc Fellowship Training Grant

National Center for Advancing Translational Sciences (NCATS)
Federal Government
United States
Unspecified amount
The Clinical & Translational Science Award TL1 Postdoc Fellowship Training Grant offers comprehensive support for biomedical researchers at Vanderbilt University. This program empowers scholars through career development tools, mentoring opportunities, and participation in national Translational Science meetings. Trainees must hold a doctoral degree and be committed to translational research while pursuing full-time training. This fellowship fosters innovation and collaboration among researchers, enhancing their contributions to the field.
Human Physiology Health & Medicine

Thomas S. Ritter Memorial Scholarship Fund

Greater Kansas City Community Foundation
Private
United States
Unspecified amount

Thomas S. Ritter Memorial Scholarship Fund

The purpose of this scholarship fund is to assist students who are attending or plan to attend a college or university and who have demonstrated a strong work ethic both inside and outside of the classroom.

Award

  • Varies
Civil Engineering STEM / STEAM Education

IMPACT: Quality of Place: Community Assets - Arts, Culture, & Heritage Grants

Erie County Gaming Revenue Authority
State/Local Government
Erie County, Pennsylvania
Up to US $15,000
The IMPACT: Quality of Place Grant Program aims to enhance community well-being, foster civic pride, and stimulate tourism through support for arts, culture, and heritage initiatives in Erie County. With a funding cap of $15,000 per application and a total of $200,000 available each grant cycle, the program encourages projects that enrich community life and support economic development. Eligible applicants include local non-profits and municipalities that meet specific criteria.
Art & Culture Community Culture & Heritage

Elmer Roe Deaver Foundation Grant

The Elmer R Deaver Foundation Idt
Private
Philadelphia County, Pennsylvania
Unspecified amount
The Elmer Roe Deaver Foundation Grant, established in 1947 by Elmer Roe Deaver, supports organizations that aid Philadelphia residents in poverty relief. Managed by Wells Fargo Bank, the foundation awards grants annually to 501(c)(3) exempt organizations focused on community welfare. This ongoing commitment to alleviating poverty underscores the foundation's significant role in enhancing the lives of those in need within the Philadelphia area.
Poverty Alleviation & Services Human & Social Services

Strategic Management Planning Program (STMP)

Pennsylvania Department of Community and Economic Development
State/Local Government
Pennsylvania
Up to US $200,000
The Strategic Management Planning Program (STMP) assists local governments in Pennsylvania by providing grants for hiring financial consultants to develop comprehensive financial and economic strategies. This proactive approach aims to avert fiscal crises and ensure long-term fiscal stability. By facilitating the creation of three to five-year financial plans, STMP empowers municipalities to enhance their managerial and economic development capabilities, ultimately strengthening their financial health and service delivery.
Economic Services & Development Community Development & Revitalization

Clarence FW and Virginia WLC Young Living Trust

Hawai'i Community Foundation
Private
Hawaii County, Hawaii, Honolulu County, Hawaii +1 more
Unspecified amount
The Clarence FW and Virginia WLC Young Living Trust provides scholarship support to Hawaii public high school graduates attending the University of Hawaii. Established in 2015, the scholarship aims to assist students who demonstrate financial need, maintain a GPA of 3.0 or higher, and are pursuing a major in Education. Eligible students must attend full-time at one of the designated University of Hawaii campuses.
Education Academic Scholarship Programs

Dorothy A. Howard Memorial Scholarship

Cumberland Community Foundation, Inc.
Private
North Carolina
Unspecified amount

Cumberland Community Foundation ("CCF") manages more than 60 scholarship endowment funds created by local individuals, families, civic organizations, and corporations who want to provide a path to higher education for future generations. 

Each year, Cumberland Community Foundation announces more than $1,000,000 in college scholarships to students from southeastern North Carolina.

Dorothy A. Howard Memorial Scholarship

Graduating senior from any high school in Cumberland County.

Education Education - Higher Education

PreservINg Main Street Grant

Indiana Office of Community and Rural Affairs
State/Local Government
Indiana
Up to US $2,000,000
The PreservINg Main Street Grant, initiated by the Indiana Office of Community and Rural Affairs, aims to enhance local economies through the preservation of historic properties in Indiana. This program supports eligible communities with funding up to $2 million for downtown revitalization projects, alongside opportunities for capacity building in partnership with Indiana Humanities and Indiana Landmarks. It offers a sustainable approach to historic preservation while fostering community engagement and economic development.
Historic Preservation Community Development & Revitalization

State Library of Ohio Library Services and Technology Act Conservation and Preservation Grant (OH)

State Library of Ohio
State/Local Government
Ohio
Up to US $4,999
The State Library of Ohio offers the Conservation and Preservation Grant, providing up to $4,999 to libraries for conserving unique items or small collections. This initiative aims to support libraries in preserving culturally significant artifacts that reflect Ohio's historic and artistic heritage. Applicants must attend a mandatory workshop to ensure successful grant applications. The workshop covers selection criteria, working with conservators, and treatment documentation, enhancing the applicant's ability to manage preservation projects.
Library Services Historical Records & Archives

Kresge Innovative Projects: Detroit Plus - Cultural Heritage Grants

Kresge Foundation
Private
Wayne County, Michigan
Up to US $100,000

About KIP:D+ Cultural Heritage

Kresge Innovative Projects: Detroit Plus (KIP:D+) funds projects in Detroit, Hamtramck and Highland Park neighborhoods that support the vision and creativity of residents. We support inclusive, collaborative processes that authentically engage community members in planning, design and implementation.

Through project funding, capacity building, and support for transformative initiatives, KIP:D+ enables grantees to foster resilience, collaboration, and meaningful change.

This round of KIP:D+ focuses on Cultural Heritage. We’re funding arts, culture, and community projects that help neighborhoods remember their history, share stories and traditions, and carry forward community legacy.

Art & Culture Community Culture & Heritage

Preckel-McAuley Scholarship Fund

Pittsburgh Foundation
Private
Pennsylvania
US $2,000

The Pittsburgh Foundation

Established in 1945, The Pittsburgh Foundation is one of the nation’s oldest community foundations and as of 2022 is the 18th largest of more than 750 similar foundations across the United States.

As a community foundation, its resources comprise endowment funds established by individuals, businesses and organizations with a passion for charitable giving and fulfilling the Foundation’s mission of improving quality of life for all in the region. The Foundation currently manages about 2,500 individual donor funds and, together with its supporting organizations and its affiliate, The Community Foundation of Westmoreland County, has assets of $1.386 billion (2022). Grantmaking benefits a broad spectrum of basic needs and development opportunities within Pittsburgh and beyond.

Scholarships

The Pittsburgh Foundation and The Community Foundation of Westmoreland County provide scholarship opportunities for local students to pursue their educational goals. Scholarships are available for graduating high school seniors, undergraduates, graduate, medical and professional school students who are attending community colleges, four-year universities and career/technical schools.

Preckel-McAuley Scholarship Fund

The Preckel-McAuley Scholarship Fund was created at The Pittsburgh Foundation to provide scholarships to students pursuing a master's degree in Archives and Information Science at the University of Pittsburgh's School of Computing and Information.

Award Type: Single Year. Previous recipients are encouraged to re-apply in consecutive years.

Education - Higher Education Computer Science & Engineering

ROSES25: C.4 Planetary Science Enabling Facilities

National Aeronautics and Space Administration (NASA)
Federal Government
United States
Unspecified amount
The Planetary Science Enabling Facilities (PSEF) program by NASA invites proposals for research facilities that support the Planetary Science Division. It aims to enhance scientific collaboration and innovation by providing resources to a diverse range of institutions, including emerging and undergraduate colleges. Proposals should highlight the scientific merit and community need for these facilities, ensuring that they serve a broad user base committed to advancing planetary science.
Planetary Science Space Science

Diversity and Inclusiveness Grant Program

American Philosophical Association Inc
Private
Canada, United States
Up to US $20,000
The Diversity and Inclusiveness Grant Program by the American Philosophical Association aims to enhance the participation of underrepresented groups in philosophy. With funding up to $20,000, the program seeks innovative projects that impact diversity across various demographics including women, racial minorities, and LGBTQ+ individuals. Proposals are evaluated on their philosophical quality, feasibility, and potential broader impact, particularly within the US and Canada, making this an essential opportunity for promoting inclusivity in philosophical discourse.
Diversity, Equity & Inclusion Philosophy

Nonprofit Security Grant Program ( WA )

Washington State Military Department
State/Local Government
Washington
Unspecified amount

About Us

The Washington Military Department’s mission is to provide trained professionals and operational forces who are ready to defend our state and nation, respond to emergencies and disasters and enhance resiliency in communities through structured alternative education opportunities for at-risk youth.

Nonprofit Security Grant Program 

NSGP provides funding support for target hardening and other physical security enhancements and activities to nonprofit organizations that are at high risk of terrorist or other extremist attack. The intent is to integrate nonprofit preparedness activities with broader state and local preparedness efforts. It is also designed to promote coordination and collaboration in emergency preparedness activities among public and private community representatives, as well as state and local government agencies.

Domestic / Homeland Security Community / Public Safety

SPRK-ing Interest in Computer Science

American Indian Science and Engineering Society (AISES)
Association/Society
American Samoa, Guam +6 more
Unspecified amount in in-kind support
The AISES SPRK-ing Interest in Computer Science program engages Indigenous K-12 students through fun coding and robotics activities. By utilizing Sphero BOLT and Indi robots, students gain hands-on experience in STEM and computer science, fostering greater interest and competency in these fields. Participating schools receive essential materials and training, promoting a culturally relevant learning experience. Priority is given to middle schools, encouraging greater participation in STEM+CS education among Native students.
Computer Science & Engineering STEM / STEAM Education

The Gunther & Lee Weigel Medical School Scholarship

Elks National Foundation Inc
Private
United States
Unspecified amount
The Gunther & Lee Weigel Medical School Scholarship is an exclusive opportunity for current and former Elks National Foundation scholarship recipients pursuing medical or osteopathic degrees. This scholarship, established in memory of Gunther Weigel, aims to support Elks scholars entering their first year of medical school. The number and amount of scholarships vary annually, reflecting the Foundation's commitment to healthcare education.
Academic Scholarship Programs Health & Medicine

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.