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$9.00B
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About Us
advancing the science of water ®
Who We Are
The Water Research Foundation (WRF) is the leading research organization advancing the science of all water to meet the evolving needs of its subscribers and the water sector. WRF is a 501(c)(3) nonprofit, educational organization that funds, manages, and publishes research on the technology, operation, and management of drinking water, wastewater, reuse, and stormwater systems—all in pursuit of ensuring water quality and improving water services to the public.
5433 - Optimizing Membrane Biofouling Control in Potable Water Reuse Treatment Trains
Grant Information
Main Objective: Evaluate alternative biofouling control chemicals and operational strategies to optimize performance across the potable reuse treatment train while maintaining treatment performance and finished-water quality. Supporting objectives include:
Klamath Water Quality Improvements Grant Program
Interim Measure 11 from the Amended Klamath Hydroelectric Settlement Agreement (KHSA), includes funding to address water quality improvements in the Klamath River via restoration and conservation actions in the Klamath Basin in Oregon. The emphasis of Interim Measure 11 (IM11) is nutrient reduction projects. PacifiCorp, in consultation with the Interim Measures Implementation Committee, developed a list of project categories to be implemented to fulfill the objective of IM11. PacifiCorp has provided funding of up to $6,433,500 for design/engineering and implementation of projects. This funding is administered through the Klamath Water Quality Improvements Grant Program.
After two grant cycles, a total of $4.9 million remains for future restoration and technical assistance projects. The next solicitation for grant applications will be in February 2026.
A Steering Committee, facilitated by the Oregon Department of Environmental Quality (ODEQ), was established to assist OWEB with the program implementation. OWEB is the Fiscal Agent and will award IM11 funds for projects approved by the Steering Committee until the funds are exhausted.
The Steering Committee is comprised of members from the following organizations: Oregon Water Resources Department, ODEQ, Oregon Department of Agriculture, Oregon Department of Fish and Wildlife, National Oceanic Atmospheric Administration, US Fish and Wildlife Service, US Bureau of Reclamation, Yurok Tribe, Karuk Tribe, Klamath Tribes, California Department of Fish and Wildlife, California North Coast Regional Water Quality Control Board and Aquatic Ecosciences.
Funding
The Centers for Structural Biology of HIV and Other Infectious Diseases aims to support innovative frontier science research that establishes new technologies and methodologies to provide insight into the mechanisms of hostpathogen interactions, as well as translational research to inform the development of novel and/or improved preventive interventions, therapeutics, diagnostics, and curative interventions across a broad spectrum of infectious diseases. These Centers focus on understanding the dynamics of molecular complexes, with the intention of informing mechanistically based discovery and/or design of interventions for the prevention, treatment, and cure of HIV and other infectious diseases. The goal is to facilitate the discovery of new therapeutic targets, new classes of interventions ranging from diagnostics, to small molecules and protein therapeutics, to neutralizing antibodies, and novel vaccine candidates, including nanoparticle vaccines, elucidate the mechanisms of action of interventions, and to determine the structural basis for interventional failures, but not support end-to-end preclinical development.
Of particular interest are the components of infectious agents and/or hosts for which sufficiently complete structureshave yet to be determined, including macromolecular complexes of proteins, nucleic acids, carbohydrates, lipid membranes, and/or small molecules. The Centers will be responsible for the validation of structural data using biological, biochemical, and computational methods and artificial intelligence (AI) models to help understand the biological mechanisms and structure-function relationships of these complexes.
Chesapeake Watershed Investments for Landscape Defense (WILD) Program
The Chesapeake Watershed Investments for Landscape Defense (WILD) Grants Program delivered in partnership with the U.S. Fish and Wildlife Service supports efforts to improve the condition and connectivity of habitats for at risk and federally listed species.
The National Fish and Wildlife Foundation (NFWF) is committed to operating in full compliance with all applicable laws, regulations, and Executive Orders. We continuously monitor legal and regulatory developments to ensure our policies, procedures, and operations align with current federal directives. We encourage all applicants to do the same.
The ability and extent to which NFWF is able to make awards is contingent upon receipt of funds from federal agencies and/or other funding partners. Final funding decisions will be made based on the applications received and the level and timing of funding received by NFWF.
The WILD Program Pillars are:
The Chesapeake WILD Grants Program has three distinct tracks:
Texas Health Community Impact
A Department of Community Health Improvement
We invest in community health and well-being through grantmaking and strategic collaborations. From data-driven, home-grown regional strategies to technical assistance, Texas Health Community Impact collaborates with community leaders to offer creative grant opportunities to North Texas organizations with a mutual desire to transform health and well-being in innovative ways.
Texas Health Community Impact Grants (Request for Proposals)
Texas Health Community Impact requests proposals to fund local organizations collaborating on innovative solutions that address barriers to community health and wellbeing. Up to $5 million is available across nine counties for the 2027-2028 grant cycle.
These community health improvement grants are made possible by Texas Health Resources—a faith‑based, nonprofit health system that cares for more patients in North Texas than any other provider.
Key Requirements
Applications must fulfill four key requirements: 1. Propose an innovative approach. 2. Demonstrate a collaborative effort between two or more organizations. 3. Align with strategic priorities. 4. Promote sustainability. Read Grant Key Requirements.
Project Implementation
Applicants must demonstrate the ability to begin implementing activities within four months of the execution of the MOU. Exceptions may be considered on a case-by-case basis.
Prior Applicants
Organizations that applied for a previous Texas Health Community Impact grant cycle and were not awarded are eligible to apply.
Request for Proposals by Region
The Texas Health Community Impact Grant requests proposals by regions: 1) Collin Region; 2) Dallas and Kaufman Region; 3) Denton, Wise and Parker Region; 4) Southern Region; and 5) Tarrant Region.
Texas Health is investing a total of $5 million in grants across its five regions, which spans nine counties. Groups seeking to work collaboratively on innovative upstream approaches to address priorities identified in each region are encouraged to apply for this competitive funding opportunity.
Collin-Specific Content
Problem Statement
Based on extensive community feedback and analysis of data in the 2025 CHNA, as well as input from the Collin Leadership Council, the following non-medical drivers of health (NMODH) have been identified as top concerns in Collin County: Healthcare Access, Navigation & Literacy and Connectedness. Therefore, the Collin Leadership Council will seek innovative proposals to reduce barriers related to NMDOH in Healthcare Access, Literacy & Navigation, as well as Connectedness, through enhanced access to nutrition, chronic disease management, primary care, and social connectedness in 4 high need zip codes: East McKinney (75069), Farmersville (75442), Princeton (75407), and Blue Ridge (75424).
Operating grants for nonprofits provide essential funding to support day-to-day operations, staff salaries, and infrastructure. The following grants help organizations build capacity, maintain sustainability, and focus on achieving their mission-driven goals.
Explore 8,000+ funding opportunities for operational support, with $3.34B in resources. Instrumentl helps nonprofits secure essential funding by offering grant discovery tools, deadline tracking, and strategic funder analysis to ensure long-term success.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Operating grants for Nonprofits?
Most grants are due in the first quarter.
What's the typical grant amount funded for Operating Grants for Nonprofits?
Grants are most commonly $32,500.
Nonprofits of all types can apply for operating grants, but they are especially useful for organizations needing flexible funding to support the core work of their mission. Operating grants are ideal for nonprofits involved in general population well-being. Specific sectors include healthcare, education, social services, and the arts. Unlike project-based grants that fund specific initiatives, operating grants help with essential costs like staff salaries, rent, and general admin costs. Funders often look for groups with a clear mission who serve a meaningful purpose and have potential for long-term impact.
Based on Instrumentl’s live grant database for operating, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Operating grants exist to help nonprofits function smoothly and grow effectively. The goal is to give organizations the financial means they need to focus on their mission, serve their communities, and support long-term stability. These grants allow nonprofits to improve everyday operations, invest in staff development, and expand programs. Funders want to see nonprofits thrive, not just survive, and providing operational support is a key element to making that happen.
Funding for operating grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Operating grants are often funded by private foundations like the popular Ford Foundation. Some government agencies offer grants to strengthen nonprofit infrastructure, especially in sectors like health, education, and social services. Corporate giving programs may also support nonprofits that align with their values and create lasting impact.
To improve the chances of getting operating grants, nonprofits should:
For more advice on finding and winning operating grants, check out our step-by-step guide to general operating grants.
Instrumentl simplifies the process of applying for operating grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.
Check out how Habitat for Humanity delivered over 200% ROI within just a few weeks.