Best Large Grants for Nonprofit Organizations

About

Community Foundation of Greenville bridges philanthropy and purpose in Greenville County, helping people make their charitable giving simpler and more powerful for 70 years. We strategically match diverse needs and opportunities in Greenville County with philanthropic resources.

Vision:

Community Foundation of Greenville will be the leading catalyst for developing assets and unlocking potential to meet the needs of an inclusive and equitable community.

Mission:

Community Foundation of Greenville improves the lives of Greenville County residents through strategic philanthropy, community investment, and collaborative leadership.

New Leaf Fund

Community Foundation of Greenville administers grants to preserve parks, open spaces, and historical and cultural assets through the New Leaf Fund.

The New Leaf Fund was established in 2025 by a Greenville native with a passion for conservation.

Established 501c(3) organizations and local municipalities are invited by the New Leaf Fund Committee to apply online through Community Foundation’s website during the spring, summer, and/or winter grant cycles.

The Foundation encourages grant requests that include the protection of land and waterfront areas, increased tree cover and access to green spaces, and the protection and restoration of historical properties, in the City of Greenville, in Greenville County, and, to a lesser degree, in the Upstate.

Every Dream of Parenthood Deserves a Chance

Making dreams of parenthood a reality, one grant and one bundle of joy at a time.

Our Mission

The Samantha and Kyle Busch Bundle of Joy Fund is dedicated to advancing access to IVF care and coverage, increasing awareness and providing support so others don’t have to navigate infertility alone.

Apply for a Grant

Your Journey to Parenthood Begins Here

We distribute grant awards up to three times annually.

Please note that the number of grants and funding amounts fluctuate based on:

1) the unique needs of our applicants, and

2) the success of our fundraising efforts.

Our mission is to help as many people as possible.

About Us

Making a Difference, Together

The Community Foundation of Monroe County (CFMC) builds a thriving, inclusive community through the power of philanthropy. By connecting generous donors with local causes, we help ensure Monroe County remains a place where everyone can thrive. Since our founding, we’ve been a trusted steward of community resources, fostering impactful collaborations and sustainable solutions to address challenges in education, health, poverty, and community development.

Skilled Trades Scholarship

The Greater Milan Area Community Fund is proud to support students pursuing skilled trades and hands-on career pathways that build practical skills, open doors to stable employment, and strengthen our local community.

Scholarship awards are typically paid directly to the accredited trade program or educational institution and are generally non-taxable.

Applications are evaluated two times each year for awarding in the six months after application and selection.

About MOHCD and This Funding Opportunity

Our Mission

The mission of the Mayor’s Office of Housing and Community Development (MOHCD) is to support San Franciscans with affordable housing opportunities and essential services that help build strong communities.

Housing Place-Based Services Request for Proposals

Through this RFP, MOHCD seeks nonprofit partners to provide place-based services that help maintain housing stability and reduce displacement among residents of federally subsidized housing properties. These funds will support effective, accessible, and culturally responsive Housing Place-Based Services that advance individual and collective opportunity, support community resilience, and strengthen housing stability.

Services funded through this RFP shall be delivered on-site to extremely low-income residents of federally subsidized affordable housing developments and/or cooperatives.

The Greater Milwaukee Foundation Grant Cycle 1 supports projects and programs that align with priorities for creating a Milwaukee for all. Funding is available for arts, basic needs, housing, and physical health initiatives. Eligible applicants include 501(c)(3) organizations and governmental agencies, with specific requirements for board diversity. The foundation does not fund individuals, for-profit organizations, or partisan activities. The grant cycle accepts one application per organization.

Environmental Stewardship: Community Grants

FAO, through its Environmental Stewardship Pillar of Prosperity Fund, offers funding opportunities to advance conservation, environmental stewardship and the greater well-being of Appalachian Ohio.

To support locally driven projects that preserve and enhance our natural environment.

Community grants empower local communities to preserve and enhance our natural environment.

We know relatively modest projects can make an outsized difference when they promote environmental stewardship and engage whole communities in conservation. More details about these grants and how to apply can be found on page 5. At least $50,000 is available to support community grants.

The Washington County Community Foundation offers Internship Grants aimed at enhancing the quality of life in Washington County. These grants support nonprofit organizations by providing monetary stipends for student interns engaged in services while enrolled in accredited post-secondary education. With a commitment to philanthropy, the Foundation ensures effective charitable giving, promoting community improvement across various focus areas, including education, health, and arts.

The Atlanta Foundation Grant aims to enhance the welfare of communities in Fulton and DeKalb counties, Georgia. Established in 1921, the foundation focuses on supporting charitable and educational institutions that foster education, scientific research, and community well-being. Grants are available for qualified 501(c)(3) organizations within these counties, emphasizing program grants and operating projects. The foundation is committed to improving the lives of residents, irrespective of their race or creed, ensuring a positive impact on the community.

The Joint Institute for Wood Products Innovation Grant for FY 2025-2026, sponsored by the California Board of Forestry, aims to enhance sustainable forest restoration efforts across California. This grant focuses on projects that support long-term ecosystem sustainability, carbon storage, and innovative wood products. Eligible activities include research and development in biomass utilization and workforce development, with a preference for projects that meet current state needs in advancing wood and biomass utilization.

The Institute of Sacred Music (ISM) Fellowship at Yale University offers long-term fellowships for scholars and artists whose work aligns with the Institute's mission. Each year, a diverse group of fellows engages in interdisciplinary projects, exploring areas from Buddhist chant to African American sacred music. This fellowship provides access to Yale's rich resources, allowing fellows to teach courses and participate actively in a vibrant academic community, fostering the integration of arts and theology.

The Robert C. Hoffman Charitable Endowment Trust offers semi-annual grants to nonprofit organizations benefiting residents of Adams County, PA. The trust aims to promote social welfare by supporting various causes, including education, animal welfare, and assistance for the needy. Eligible applicants must have 501(c)(3) status. Grants are not provided for organizations outside of Adams County unless a clear benefit to local residents can be demonstrated. This initiative strengthens community support and addresses local needs.

The Young Scientists Summer Program (YSSP) at IIASA invites advanced Ph.D. students to apply for research opportunities that address global challenges. This program, running since 1977, supports interdisciplinary projects and offers stipends, typically €1700 monthly plus airfare. Participants will engage with 50 peers and senior researchers, contributing to IIASA's mission of advancing systems analysis. Applicants should ensure their research aligns with IIASA's agenda and be prepared for the program's full three-month duration in Laxenburg, Austria.

The PSEG Foundation provides funding for events and initiatives that enhance community safety and environmental stewardship in areas where they operate, such as New Jersey and New York. Organizations must be 501(c)(3) nonprofits that align with the foundation's focus areas, including sustainable neighborhoods and safety preparedness. The application process is rolling, with a response time of 8 to 12 weeks. Proposals must be submitted online between January 1 and October 31, at least eight weeks before the event.

The Peridot Foundation Grant aims to enhance the welfare of the Hebron, Connecticut community by supporting local charitable organizations. This includes funding for children's programs, public safety initiatives, and community services. Additionally, the foundation promotes medical research activities and provides assistance to various charitable organizations. Through these efforts, the Peridot Foundation seeks to create a positive impact on the lives of residents and foster a spirit of giving within the community.

James H Cummings Foundation

The James H. Cummings Foundation is a charitable, not-for-profit corporation organized in New York State in July, 1962 for the purpose of complying with certain provisions in the will of its founder and namesake. Admired for his unassuming manner, friendly demeanor, and quiet generosity, Cummings was dedicated to giving back to the communities he once called home.

The Foundation’s focus is on funding not-for-profits making strides in medical research, science and post-secondary education in Buffalo, Toronto, and Hendersonville, North Carolina. In addition, we focus on funding programming for vulnerable people of all ages—children to older adults—in Buffalo and Hendersonville.

James H Cummings Foundation Grants

Our Focus

The Foundation focuses on supporting 501 (c)(3) not-for-profit organizations whose missions and services align with our guidelines and mission:

• To advance medical research, science, and post-secondary medical education in Buffalo and Hendersonville, North Carolina.
• To provide services for vulnerable children and children with disabilities that will enhance high school graduation rates with a focus on the quality of out-of-school (before and after school and summer care) for school age children and early care and education programs and initiatives in Buffalo and Hendersonville, North Carolina.
• To assist older adults and vulnerable adults with services that help them maintain independent, healthy, and active lifestyles, remaining in their own homes when possible in Buffalo and Hendersonville, North Carolina.
• To advance medical research in Toronto.

James H Cummings Foundation

The James H. Cummings Foundation is a charitable, not-for-profit corporation organized in New York State in July, 1962 for the purpose of complying with certain provisions in the will of its founder and namesake. Admired for his unassuming manner, friendly demeanor, and quiet generosity, Cummings was dedicated to giving back to the communities he once called home.

The Foundation’s focus is on funding not-for-profits making strides in medical research, science and post-secondary education in Buffalo, Toronto, and Hendersonville, North Carolina. In addition, we focus on funding programming for vulnerable people of all ages—children to older adults—in Buffalo and Hendersonville.

James H Cummings Foundation Grants

Our Focus

The Foundation focuses on supporting 501 (c)(3) not-for-profit organizations whose missions and services align with our guidelines and mission:

• To advance medical research, science, and post-secondary medical education in Buffalo and Hendersonville, North Carolina.
• To provide services for vulnerable children and children with disabilities that will enhance high school graduation rates with a focus on the quality of out-of-school (before and after school and summer care) for school age children and early care and education programs and initiatives in Buffalo and Hendersonville, North Carolina.
• To assist older adults and vulnerable adults with services that help them maintain independent, healthy, and active lifestyles, remaining in their own homes when possible in Buffalo and Hendersonville, North Carolina.
• To advance medical research in Toronto.

The Youth4Climate initiative, led by the Government of Italy and UNDP, empowers young people to drive impactful climate action by providing up to $30,000 for innovative solutions. This funding targets five key areas: Climate Literacy, Sustainable Energy, Food and Agriculture, Nature Assets, and Sustainable Consumption. Successful applicants will gain access to technical support, mentorship, and storytelling platforms, ensuring their projects can thrive and inspire change on a global scale.

The Institute of Sacred Music (ISM) Fellowship offers short-term opportunities for scholars and artists to engage with Yale's rich collections. This fellowship, lasting one to three months, enables fellows to research various aspects of religious thought and practice. It promotes interdisciplinary collaboration across fields such as anthropology, musicology, and theology. Ideal for doctoral students or scholars with terminal degrees, the fellowship supports projects that align with the ISM's mission of fostering the arts in human flourishing.

The Institute of Sacred Music (ISM) Fellowship at Yale University offers postdoctoral associates a unique opportunity to engage in interdisciplinary research and artistic projects. Selected fellows will contribute to the vibrant community of the ISM, collaborating with faculty and students across various disciplines. The fellowship includes financial support ranging from $65,000 to $76,000, with a focus on teaching and scholarly engagement. This program encourages diversity and welcomes applicants from all backgrounds.

The Harvard Radcliffe Fellowship offers a unique opportunity for scholars, artists, and public intellectuals to engage deeply in their projects within a diverse and interdisciplinary community. Each year, 50 fellowships are awarded, encouraging applications from various fields, including humanities, social sciences, and creative arts. The program emphasizes diversity, collegiality, and creativity, welcoming individual or group applications. Fellows benefit from Harvard's extensive resources, allowing them to challenge conventions and explore innovative ideas.

The Eco-Living Fund Grant, managed by the Charlottesville Area Community Foundation, seeks to promote sustainable living through projects that encourage zero-footprint and net-positive practices. Eligible applicants include tax-exempt organizations and government agencies within the foundation's service area. Grants support initiatives that demonstrate measurable outcomes in resource conservation and community engagement. The fund aims for projects that not only enhance environmental sustainability but can also serve as models for broader change, potentially saving costs for participants.

The Fifth Third Foundation in Evansville, IN, focuses on funding programs that foster community development, health services, education, and the arts. Eligible applicants include 501(c)(3) nonprofits serving designated regions, such as Evansville and Chicago. The foundation prioritizes organizations with a history of recent funding. Notably, grants cannot support individuals or certain event sponsorships. This strategic approach aims to create meaningful impacts in communities by aligning resources with local needs.

The Wolpoff Family Foundation Grant seeks to support established organizations in Montgomery County, Maryland, that have been operational for at least five years. This foundation aims to foster community development, education, and medical research, and invites re-applications from previously funded organizations. Grants are available for specific initiatives, with a maximum award of $15,000 for first-time grantees, focusing on measurable impacts and community needs.

The Kirkpatrick Family Fund offers Project Support through small grants aimed at enhancing community quality of life in central Oklahoma. Eligible projects must achieve measurable outcomes within a specific timeframe and align with the organization's mission. The fund prioritizes support for arts, education, health, and community development initiatives. Importantly, it excludes requests for ongoing program support or capital projects, ensuring a focus on impactful, time-limited projects that benefit local communities.

The James A. & Faith Knight Foundation Grant supports nonprofit organizations in Jackson and Washtenaw Counties, Michigan. The foundation values sound financial management, governance practices, and a clear mission, with a focus on gender, diversity, and outcomes. Key funding priorities include general operating support, environmental sustainability, and initiatives benefiting women and girls. Organizations are expected to demonstrate their commitment to these values during the application process, which may include site visits.

The CFES Workforce Development Grant supports programs aimed at enhancing job training and career advancement, particularly for underrepresented groups such as individuals with disabilities and non-traditional students. With a maximum funding of $7,500, the grant prioritizes collaborative efforts that demonstrate a commitment to quality education and workforce development. Eligible applicants include IRS-designated nonprofits and educational institutions serving Maryland's Wicomico, Worcester, and Somerset Counties.

The Greater Milwaukee Foundation's GMF: Cycle 2 - Project Support initiative offers funding for projects that enhance early childhood education, mental health services, and workforce development in the Milwaukee area. With grants of up to $50,000 per year for three years, the foundation prioritizes applications that promote racial equity and support community-led initiatives. Eligible organizations include 501(c)(3) nonprofits and governmental agencies, with a focus on creating equitable opportunities for all residents.