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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

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$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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The Alan Jutzi Residential Fellowship for Non-Traditional Scholars

The Huntington Library, Art Museum, and Botanical Gardens (The Huntington)
Private
Los Angeles County, California
US $3,500 - US $7,000
The Alan Jutzi Residential Fellowship supports independent scholars for one to three months of research at The Huntington. With a monthly award of $4,000, it encourages diverse scholarship and creativity. Open to scholars of any nationality, it requires applicants to commit to their fellowship period and articulate their research goals clearly. This fellowship is ideal for those without academic affiliations, fostering transformative educational experiences.
Architecture Urban Planning Writing & Literature +5 more

Pott Foundation Grant

The Pott Foundation
Private
Missouri
Unspecified amount

The Pott Foundation

The Pott Foundation was established in 1963 by Herman T. Pott. The grant making process is overseen by an Advisory Committee made up of seven members. This Committee, four of whom are descendants of Herman and Phenie Pott, determines how the funds will be distributed to accomplish the mission of the trust.

The Advisory Committee of the Pott Foundation honors the values that were important to Herman T. Pott and Phenie R. Pott; children, education and health and human services. Most of the grant recipients are located in Herman Pott's adopted city of St. Louis, Missouri. The Foundation distributes approximately $1.5 million annually to over 100 charities.

Grant Guidelines and Helpful Hints

The following information will be useful for organizations inquiring about grants from the Pott Foundation.

The fiscal year of the Foundation is January 1 - December 31.

 

Health & Medicine Child Welfare Services Academic Scholarship Programs +4 more

Mitsui U.S.A. Foundation Grant

Mitsui U.S.A. Foundation
Private
Cook County, Illinois, Davidson County, Tennessee +7 more
Unspecified amount
The Mitsui U.S.A. Foundation, established in 1987, focuses on supporting educational and community welfare initiatives across the U.S. It prioritizes qualified 501(c)(3) organizations that enhance the quality of life, particularly through international education and U.S.-Japan exchanges. With over 50 active programs, the Foundation promotes good corporate citizenship and encourages employee volunteerism while avoiding support for individuals, political groups, or non-monetary requests. Collaboration with local Mitsui offices is preferred.
Disability Care & Services Child Welfare Services Youth Services +7 more

Cullum Foundation Grant

Cullum Foundation
Private
Georgia (US state)
Unspecified amount
The Cullum Foundation Grant supports qualified 501(c)(3) organizations primarily in Augusta, Georgia, and Richmond County. Established in memory of Henry C. Cullum, the foundation aims to alleviate suffering, support education for youth, and maintain churches. Organizations seeking funding must submit applications online and demonstrate their alignment with the foundation's mission to improve the welfare of individuals in need, focusing on health, education, and human services.
Education - K through 12 Education - Higher Education Poverty Alleviation & Services +6 more

CNPS Student Research Grants Program

California Native Plant Society
Association/Society
California
Up to US $1,500
The CNPS Student Research Grants Program supports research on California's native flora, aiming to protect these vital plants and their habitats. Founded in 1983, it encourages diverse applicants, including underrepresented groups in science. Grants are awarded based on alignment with CNPS's mission and the significance of the research in areas like conservation and ecology. The program honors several awards, including the Doc Burr and Hardman Native Plant Research Awards, to promote innovative botanical studies.
Horticulture & Gardening Forestry Botanical Conservation +1 more

HRBT Foundation Grants

Hudson River Bank & Trust Company Foundation
Private
Columbia County, New York
Unspecified amount
The HRBT Foundation offers grants to support various community-focused projects, emphasizing areas like health care, education, and environmental protection. Organizations recognized as tax-exempt by the IRS can apply for funding, with a streamlined process for requests under $1,000. The foundation prioritizes specific project funding over general support and does not accept multiple requests from the same organization within a calendar year.
Historic Preservation Art & Culture Education +6 more

Mathews CF - Community Impact Grants

The Community Foundation for a Greater Richmond
Private
Mathews County, Virginia
Unspecified amount
The Mathews CF Community Impact Grants support local nonprofits to enhance cultural vibrancy, economic prosperity, educational success, and health and wellness in Mathews County. Funded by generous donors, the program focuses on impactful projects that yield positive, lasting changes. Eligible organizations include 501(c)(3) charities, which may apply once a year. This initiative fosters collaboration with grantees to achieve essential community goals and adapt to evolving needs.
Art & Culture Economic Services & Development Community / Public Safety +6 more

Tama County Grants

Community Foundation of Northeast Iowa
Private
Tama County, Iowa
More than US $1,000
The Tama County Community Foundation, an affiliate of the Community Foundation of Northeast Iowa, aims to enhance the quality of life in Tama County through strategic grantmaking. By supporting local nonprofits and encouraging community engagement, the foundation fosters vibrant communities and addresses key local needs. With a focus on opportunity, health, safety, and youth empowerment, the foundation guides its funding priorities to ensure impactful and sustainable community development. Together, they strive to create a thriving region for all residents.
Youth Development & Leadership Rural Development Health Disparities & Social Determinants of Health +5 more

The Arras Foundation: Healthy Community Grant

The Arras Foundation
Private
Chester County, South Carolina, Lancaster County, South Carolina
Unspecified amount
The Arras Foundation's Healthy Community Grant supports community nonprofits in Fort Lawn, Great Falls, and Lancaster County. The grant aims to promote healthier communities through collaboration and innovative solutions that leverage community assets. Interested applicants must complete pre-proposal steps, including workshops and exploratory meetings, before submitting their Letter of Inquiry. The Foundation invites eligible organizations to join their mission of fostering positive change and enhancing community well-being.
Economic Services & Development Health Care Access & Delivery Human & Social Services +4 more

Alaska Nita M. Lowey 21st Century Community Learning Centers

Alaska Department of Education & Early Development
State/Local Government
Alaska
US $50,000 - US $900,000
The Alaska Nita M. Lowey 21st Century Community Learning Centers grant aims to enhance student learning beyond school hours. With approximately $3.7 million available annually, the program focuses on students from high-poverty schools, fostering academic achievement through community learning centers. These centers provide academic support and enrichment activities, such as STEM, arts, and counseling, while encouraging partnerships with local organizations to improve program quality and sustainability. Grants will be awarded for a five-year period, starting in 2025.
Academic Success & Enrichment Educational Access & Equity Education - K through 12 +6 more

Sherwood Foundation: Operating Grants

The Sherwood Foundation
Private
Nebraska
Unspecified amount

Mission

The Sherwood Foundation® promotes equity through social justice initiatives enhancing the quality of life in Nebraska.

Vision

We believe social justice is the proactive reinforcement of policies, practices, attitudes, and actions that all produce equitable power, access, opportunities, treatment, impacts, and outcomes for all.

Who We Fund

The Sherwood Foundation limits grants to organizations that are tax-exempt under section 501(c)(3), government entities, schools, or churches that are serving Nebraska. These organizations must be in good standing with the Internal Revenue Service. 

What We Fund

The Sherwood Foundation limits grants to nonprofit 501(c)(3) organizations that predominately benefit those that are serving Nebraska and must address one of our categories:

Urban Community Partnerships

Our work in Nebraska’s urban communities focuses on family stability and child wellbeing with an overarching emphasis on community context. Using a two-generation approach, we are interested in the relationship between direct service provision and the greater systems that impact a community. Applicants are wise to cite specific research that influences a service model or approach to solving a community challenge.

Omaha Public Schools

Guidelines: 

  • OPS employees must obtain approval from the District before submitting an application. 
  • Applications lacking such documentation will not receive consideration.
  • For assistance, please contact the OPS Grant Coordinator at 531.299.9653.

Greater Nebraska Initiatives

Through these grants, The Sherwood Foundation promotes equity and inclusion as pathways for creating the good life for all in Nebraska.  Core areas of work include child welfare, immigrant inclusion, housing, advocacy & civic engagement, leadership, and community infrastructure. Requests from communities outside of the Omaha and Lincoln metro areas are considered during standard grant cycles.

Early Childhood Education

The Sherwood Foundation supports early childhood education on a regional and national basis through The Buffett Early Childhood Fund.

What the Sherwood Foundation Values

 The Sherwood Foundation has strongly held values regarding civil liberties, equality and fairness with a particular focus on women and people oppressed because of their race, sexual orientation, and/or religion or lack-thereof.

  • We respect that not all nonprofit organizations share the same values as the Foundation.
  • We don’t ask nonprofits to change values for us or for funding.
  • We do ask that nonprofits leaders respect our values and save everyone time and energy by not seeking funding if our organizational values aren’t aligned.

Equal rights.

We believe all humans are created equal. We work to eliminate government and social barriers to equality.

Access to civic life.

We are proud to live in a democracy and believe that the rights provided to individuals in the United States should be protected and the best way to protect those rights is to ensure equal access to the voting polls. 

Reproductive justice.

We support a woman’s right to self-determination about reproductive health choices. We expect our grantees serving women and girls to ensure access and education to all health care options, including abortion. 

Opportunity to thrive.

We believe a zip code should not determine the outcome of a life. We see how government institutions and laws have historically and do presently oppress and suppress opportunity, particularly for people of color but also other minority populations and women. We work with our community to undo systemic oppression and build systems that meet the needs of citizens and do not further oppress. We seek economic justice for our neighbors and the opportunity that lies therein.

Access to services.

We expect grantees to ensure that clients have access to services and that service providers work to remove barriers rather than create barriers to care and compassion. A service provider’s religious belief system should not be imposed upon those who seek their services, whether through proselytization, coercion, guilt, or an unspoken quid-pro-quo expectation to participate in faith-based classes or religious services.

Operating Grants

The Sherwood Foundation® believes that providing operating support can make all the difference to nonprofit organizations by providing flexible funding to cover the ongoing costs of day-to-day operations (administrative/overhead). This type of support can free nonprofits to become more strategic about how they address community issues, craft internal solutions to enhance effectiveness, and build organizational infrastructure.

Education - Preschool / Early Learning Civic Engagement & Education Civic Leadership Development +8 more

WKCF: Urgent Needs Fund Grants

Western Kansas Community Foundation
Private
Finney County, Kansas, Grant County, Kansas +13 more
Up to US $3,500
The WKCF Urgent Needs Fund provides immediate financial support to nonprofit organizations facing urgent challenges, including lost revenue and increased programming due to crises like COVID-19. This fund operates without set application deadlines, allowing for continuous access to funding. Organizations can apply multiple times, with a maximum funding limit of $3,500 per year. The fund excludes certain requests, such as individual grants, capital campaigns, and projects that discriminate based on personal characteristics.
Food Delivery & Distribution Services Supportive Housing & Shelters Health Care Access & Delivery +3 more

UniBank Community Giving

Unibank Charitable Foundation Inc
Private
Middlesex County, Massachusetts, Worcester County, Massachusetts
Unspecified amount
UniBank Community Giving is dedicated to enhancing local communities through charitable contributions. With over $750,000 allocated annually, it supports initiatives in youth development, community development, affordable housing, and environmental concerns. Established in 2018 with a foundation of $2 million, UniBank aims to fortify its commitment to community service. Organizations with proven success and collaboration efforts are encouraged to apply, ensuring timely funding decisions for impactful projects.
Environmental Conservation Community Development & Revitalization Equitable & Affordable Housing +4 more

MCF: Equity Fund Grant

Maine Community Foundation
Private
Maine
Up to US $10,000
The MCF: Equity Fund Grant, established by the Maine Community Foundation, aims to strengthen LGBTQ+ organizations in Maine through general and project grants. Eligible applicants include nonprofit organizations, municipalities, and public agencies that engage LGBTQ+ individuals in their leadership and services. This grant prioritizes initiatives that enhance healthcare access, reduce disparities, and promote respect. The fund, which became permanent in 2000, continues to support community-based efforts that align with its mission.
Civil Rights Social Justice / Human Rights Health Care Access & Delivery +4 more

Generous Acts Grant Program

Adirondack Foundation
Private
Clinton County, New York, Essex County, New York +6 more
US $2,500 - US $30,000
The Generous Acts Grant Program, backed by the Adirondack Foundation, supports nonprofits and community organizations in the Adirondack Region. Since 2014, it has allocated over $1 million to initiatives addressing basic needs, educational pathways, and economic vitality. Grants range from $2,500 to $30,000, focusing on underserved populations and promoting collaboration for a more inclusive future. Applicants are encouraged to align their proposals with the program's mission to tackle racial and economic disparities.
Senior Services Early Childhood Development Basic Human Needs +6 more

Human Service Fund (HSF) : Small Grants

United Community Services Of Johnson County Inc
Private
Johnson County, Kansas
Up to US $5,000
The Human Service Fund (HSF) offers small grants aimed at 501(c)(3) organizations in Johnson County with annual budgets under $400,000. This initiative supports programs that enhance self-sufficiency and well-being among residents. In 2026, HSF allocated $473,880 to 19 programs, providing vital services to over 65,000 individuals. Eligible applicants can request up to $5,000 to develop specific services for 2027, fostering community resilience and addressing local needs.
Homelessness Services Mental Health & Psychiatric Diseases Family Services +6 more

Wawa Foundation: Financial Grants (Grants over $2,500)

Wawa Foundation
Corporate
Delaware, District of Columbia +5 more
More than US $2,500
The Wawa Foundation offers financial grants exceeding $2,500 to 501(c)(3) non-profit organizations in its six-state market, focusing on health, hunger, and supporting everyday heroes. Applications are accepted in January, April, July, and October, with grant requests reviewed prior to the next submission window. Eligible organizations include those working to improve lives through health initiatives, hunger relief efforts, and support for community heroes. For more details, visit the Wawa Foundation's official site.
Food Access & Hunger Health & Medicine Police & Law Enforcement +5 more

Art & Culture Grant

Community Foundation of Broward
Private
Broward County, Florida
Unspecified amount
The Art & Culture Grant aims to enhance community well-being through the arts, highlighting their importance in fostering connection and creativity. The Community Foundation of Broward supports nonprofits in expanding access to diverse cultural programs that engage all residents, including marginalized groups. The initiative seeks to revitalize the arts sector, which has faced economic challenges, by funding projects that promote healing, dialogue, and the celebration of cultural heritage across Broward County.
Art & Culture Community Culture & Heritage Art Education +7 more

Human Service Fund (HSF) : Regular Grants

United Community Services Of Johnson County Inc
Private
Johnson County, Kansas
US $5,000 - US $60,000

About UCS

Since 1967, United Community Services has been a catalyst and resource to ensure that the human service system meets the needs of Johnson County, Kansas, residents. UCS is part of United Way of Greater Kansas City’s Impact 100 and provides information, trends analysis and documentation to enhance community-wide planning and decision-making. By promoting upstream, proactive approaches, UCS supports sustainable solutions that improve the long-term well-being of the entire community.

Overview

The Human Service Fund (HSF) is a pool of general tax dollars from local municipalities and County government that invest their support in area non-profit agency programs that help avoid, defer, or reduce costs that would otherwise be incurred by city or County governments. UCS provides local governments with a structured accountable system through which non-profit agencies competitively apply for and access funds to serve Johnson County residents. 

Initiated by County Commissioners in 1980, cities joined the partnership in 1990. In 2026, $473,880 was awarded to 19 programs that promote self-sufficiency and build well-being for Johnson County residents. In 2025, HSF grantees provided over 243,000 units of service – including medical and dental appointments, nights of shelter, job training and more – to nearly 65,000 Johnson County residents. 

Human Service Fund (HSF) : Regular Grants

501(c)(3) applicants who are current HSF grantees or are new applicants with an annual budget greater than $400,000 or seeking a grant amount of $5,000 or up to $60,000 for specific program(s)/service(s) to be delivered in 2027 that meet HSF Funding Priorities.

Homelessness Services Mental Health & Psychiatric Diseases Family Services +6 more

LCRA Community Grants

Lower Colorado River Authority
State/Local Government
Aransas County, Texas, Austin County, Texas +71 more
Up to US $100,000
The LCRA Community Grants program supports local communities with financial assistance of up to $50,000 for capital improvement projects aimed at enhancing community assets. Established in 1995, it prioritizes projects that benefit the broader community, particularly in economically challenged areas. Eligible applicants include nonprofit organizations and local governments located within LCRA's service area. Noteworthy projects may qualify for additional funding, emphasizing wildfire response and energy conservation.
Community Development & Revitalization Firefighting & Fire Prevention Water Resource Management +2 more

Family & Neighborhood Stability Grant

McNeely Foundation
Private
Ramsey County, Minnesota
Unspecified amount
The Family & Neighborhood Stability Grant by the McNeely Foundation aims to enhance the economic vitality and stability of youth and low-income families in East Side St. Paul. The foundation prioritizes organizations that provide financial literacy, supportive housing services, and employment training. It welcomes applications from tax-exempt non-profits and public agencies, focusing on programs that foster community development and individual empowerment. Grants are awarded primarily for program support, with a strong emphasis on data-driven strategies and community partnerships.
Financial Literacy Real Estate & Housing Supportive Housing & Shelters +3 more

GA Arts: General Operating Support Grant

Georgia Council for the Arts
State/Local Government
Georgia (US state)
US $10,000
The GA Arts: General Operating Support Grant, provided by the Georgia Council for the Arts, aims to support nonprofit arts organizations in Georgia. This grant facilitates the growth of community engagement through various art forms, including performing, visual, and media arts. Eligible organizations must have a primary arts mission and offer significant arts-based programming. By fostering creativity and cultural expression, this grant helps enhance the vibrancy of Georgia's communities.
Art & Culture STEM / STEAM Education Writing & Literature +9 more

Progress Alliance of Washington Grant - Core Grants

Washington Progress Fund
Private
Washington
US $25,000 - US $100,000
The Progress Alliance of Washington Grant focuses on empowering organizations that build political power, particularly for Black, Indigenous, and People of Color communities. Through strategic investments, the grant aims to strengthen a diverse and inclusive progressive movement in Washington. The funding prioritizes long-term relationships, impactful policy solutions, and tools that enhance movement capacity. Core Grants are awarded to partners committed to fostering civic engagement and ensuring democracy works for everyone.
Black American Services Indigenous Sovereignty & Rights Indigenous Services +6 more

RAF Better Communities Grants: Fall Focus Areas

Rochester Area Foundation
Private
Olmsted County, Minnesota
US $10,000 - US $20,000
The RAF Better Communities Grants focus on enhancing quality of life in the Rochester area through unrestricted funding for nonprofits. With a commitment to equity, these grants support historically marginalized communities and basic needs, promoting growth and resilience. Organizations can apply for funding between $10,000 and $20,000 annually, with a particular emphasis on operational support. This initiative aims to empower nonprofits and strengthen community infrastructure, ensuring sustained impact and collaboration.
Basic Human Needs Social Justice / Human Rights Disability Care & Services +7 more

Water Project Fund - New Mexico Unit Fund Pilot Cycle II

New Mexico Financing Authority
State/Local Government
Catron County, New Mexico, Grant County, New Mexico +2 more
Unspecified amount
The Water Project Fund in New Mexico is inviting applications for the planning and design of water utilization projects aimed at addressing supply demands in the southwestern region. This initiative, supported by the New Mexico Finance Authority, will focus on promoting water conservation, developing sustainable water delivery systems, and enhancing watershed health. Applications for construction funding are anticipated to be available soon, with the Interstate Stream Commission overseeing award determinations.
Water Resource Management Freshwater Conservation Environmental Engineering +1 more

AstraZeneca Young Health Programme Impact Fellowship

One Young World
Private
Countries
US $10,000 - US $50,000

Young Health Programme

The Young Health Programme (YHP) is a global disease prevention initiative, aiming to provide education for young people to feel empowered to make informed choices about their health and catalyse a global, youth-led advocacy movement.

The programme operates in over 40 countries and partners with more than 60 non-profit organisations, including UNICEF and Plan International. The YHP combines community programmes, research, advocacy, and the development of young leaders, with a focus on underserved communities.

Since its launch in 2010, the YHP has directly reached over 23 million young people, trained over 1 million, and engaged more than 23,000 AstraZeneca employees, who have volunteered their time with more than 140,000 hours.

The YHP aims to prevent the most common non-communicable diseases (NCDs), including cancer, diabetes, heart disease and respiratory disease, by addressing five main risk factors: tobacco use, unhealthy diet, physical inactivity, harmful use of alcohol, and air pollution. Additionally, the programme tackles climate-health impacts to build healthier communities, recognising, as projected in the IPCC Sixth Assessment Report, that children born after 2010 will be the first generation to enter adulthood in a world where the average temperature will reach 1.5°C above pre-industrial levels, and are expected to experience a +2°C rise within their lifetime.1

AstraZeneca Young Health Programme Impact Fellowship 2026

AstraZeneca is looking for passionate, driven young leaders to join their 2026 Young Health Programme (YHP) Impact Fellowship. The Fellowship supports young advocates to create actionable change to: 

  • Advance health equity – with a focus on acting early to prevent non-communicable diseases among young people, or supporting young people living with rare diseases.
  • Take action on climate and nature – advocating for the mitigation of the harmful effects of climate change on the health and well-being of young people.
  • Build health systems resilience – contributing to stronger health systems that prioritise earlier intervention to meet today’s needs and mitigate tomorrow’s disease burden.

Benefits

The selected Fellows will gain access to networks, funding and development opportunities, enabling them to drive a global health movement led by and for young people:

A fully-funded scholarship to attend the 2026 One Young World Summit in Cape Town, South Africa (3–6 November 2026) as well as access to the One Young World Ambassador Network and the Young Health Programme (YHP) Alumni group of other young changemakers working to improve youth health.

Structured learning and development offerings to enable them to scale their impact, including both self-directed and live learning. This includes access to the One Young World Academy, an award-winning mini-MBA programme, mentorship from AstraZeneca colleagues and professional training.

Each selected Fellow will receive a grant of either USD $10,000 or USD $50,000 (if selected as the Lead2030 winner** for Sustainable Development Goal 3, for which applicants will be automatically considered) from AstraZeneca, through their non-profit organisation. Fellows are expected to use the grant to implement a project focused on either (1) advancing health equity (2) taking action on climate and nature (3) building health systems resilience.

Health & Medicine Rare Diseases Health Care Access & Delivery +4 more

Hulston Family Foundation Grant

Hulston Family Foundation
Private
Barton County, Missouri, Bates County, Missouri +19 more
Up to US $25,000
The Hulston Family Foundation Grant supports initiatives aimed at enhancing health, education, and welfare for children and families, while addressing hunger and homelessness. The foundation prioritizes funding for organizations based in West Central and Southwest Missouri, with a focus on effective management and measurable community impact. Grants are capped at $25,000 and typically not extended beyond two consecutive years, ensuring a sustainable approach to funding community-based projects.
Education Homelessness Services Food Access & Hunger +5 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.