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Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.
32,000+
Available grants
$8.25B
Total funding
$6K
Median grant
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Healthy Living in Rural Delaware: Diabetes Wellness Program
Overview
The State of Delaware Department of Health and Social Services, Division of Public Health, seeks professional services to provide up to 500 rural Delaware residents with diabetes will receive continuous glucose monitoring (CGM) devices, when not otherwise covered by insurance, to support real-time monitoring and timely adjustments in health behaviors and medication use.
Montana Department of Public Health and Human Services
At the Montana Department of Public Health and Human Services (DPHHS), we are dedicated to our mission of serving Montanans in their communities to improve health, safety, well-being, and empower independence. As the largest executive branch agency in the state, our broad reach allows us to provide essential, community-based support where and when it matters most. Our DPHHS team is passionate about improving our clients’ lives and helping them build a more secure and independent future.
Funding Opportunities for Healthcare Professionals
Join us in a funded project and improve patient care, clinical outcomes, and staff knowledge. DPHHS has a wide variety of available grant opportunities for health improvement that fit any clinic or hospital work schedule. Interested in more than one? We can work with health systems to create an outline of activities to align grants and receive additional funding.
Diabetes Funding Opportunities: Family Healthy Weight Program Implementation; DSMES-Accreditation Recognition; Chronic Kidney Disease (CKD) QI Project; Diabetes Retinopathy QI Project; Diabetes Support Program- Walk With Ease Project; Access to Care Project; Diabetes Support Program Implementation.
Access to Care Project
Increase screening for health-related social needs and build partnerships to address health disparities. With a focus on patients who have diabetes, hypertension, and high cholesterol.
Disabled Veterans National Foundation
The Disabled Veterans National Foundation (DVNF) was established in 2007 to support veterans facing challenges that traditional systems could not fully address. From its earliest days, DVNF has been focused on closing critical gaps in care and providing resources that help veterans rebuild their lives with dignity and stability.
Guided by this commitment, DVNF developed its Health & Comfort programs, offering emergency financial assistance, housing transition support, food assistance, comfort kits, and wellness initiatives. These programs are designed to meet veterans where they are and to provide practical solutions that restore hope and stability. Today, DVNF continues to grow as a trusted national nonprofit. Every day, our team works with a clear purpose: to change lives for the men and women who have served our country.
Homeless To Housing Program - Household Comfort Support
DVNF is dedicated to assisting disabled and at-risk veterans in their transition from homelessness to permanent housing. Recognizing that securing a home is a significant milestone, DVNF understands that true stability is achieved when a house becomes a home, furnished with essential items that provide comfort and functionality. We help cover essential costs related to securing and creating comfortable housing for at-risk veterans.
The H2H Program offers comprehensive support to veterans by providing: Household Comfort Support of up to $2,000 worth of essential household items to ensure veterans have a stable, safe, and comfortable living environment.
For Financial Assistance: Payments are processed through two payment cycles each month, around the 15th and 30th. For Furniture Assistance: Once the List of Items form is completed, DVNF staff will purchase the requested items, which should arrive within 7-10 business days.
Clean Water Iowa
Iowans working together to improve & protect water quality
Iowans have a long history of working together to improve and protect water quality, and conservation work is accelerating and expanding at a record pace across the state. Today, more than 450 public & private partners are working alongside farmers, landowners, municipalities and other stakeholders throughout Iowa to improve soil health and water quality on their land as well as downstream.
IDALS Expanded Cattle and Conservation Working Lands Program
The Iowa Department of Agriculture and Land Stewardship (IDALS) is expanding its popular Cattle and Conservation Working Lands program to support cattle producers in the Greater Des Moines watershed. The program provides cost-share to help farmers and landowners convert underperforming or highly erodible acres of row crops into pasture or hay ground. This provides land and forage to support the growth of the U.S. beef herd while reducing soil erosion, filtering nitrates and improving water quality.
Montana Healthcare Foundation: Rural Health Small Grants
The Montana Healthcare Foundation offers Rural Health Small Grants for organizations located in and serving rural Montana. Through a simplified application, rural Montana organizations can apply for grants of up to $10,000 to help address a health issue in their community.
Communities face many challenges that impact health. We encourage projects that support work addressing a broad range of issues. Projects may focus on any health-related issue, for example, mental health, housing, food, child or elder care, public health, or cultural connection.
This grant initiative is intended to be a low-barrier opportunity for organizations in rural Montana that may have fewer staff and resources, making it difficult to compete for larger grants. Therefore, preference may be given to applications from organizations that are not under the umbrella or network of a larger entity. We also prioritize applications from smaller communities and those located in particularly remote areas of the state. We may also prioritize applications from communities in which MTHF has provided relatively little funding to date.
The Spaulding Foundation
The Spaulding Foundation was established in 1998 by Ruth E. Spaulding, who was born in Northside and remained a lifelong resident of Greater Cincinnati. During her life, many people were touched by her benevolent and charitable giving. This private foundation is funded by her estate.
The Spaulding Foundation focuses its grant-making in the areas of mental health, physical and mental disabilities, substance abuse/chemical addiction, and domestic violence, rape and abuse. In addition, The Foundation has continued Mrs. Spaulding’s close relationship with The Cincinnati Zoo & Botanical Garden.
The Foundation welcomes opportunities to partner with organizations sharing our common goals.
Mission
Protect. Promote. Prosper.
We safeguard Oregon's agriculture, natural resources, working lands, economies, and communities through assistance, compliance, and market support.
Fertilizer Research Program Request for Proposal
The Oregon Department of Agriculture (Department) and the Fertilizer Research Committee are soliciting grant applications for the distribution of research funds collected by the Department’s Fertilizer Program.
Funding for fertilizer research is administered by the Department to provide grants addressing the interaction of fertilizers, agricultural amendments, agricultural minerals, or lime products with ground or surface water (ORS 633.465 (3)). Funding for this specific purpose is derived from an inspection fee based on tons of fertilizer, agricultural mineral, agricultural amendment and lime products distributed into Oregon. Grant awards are made annually subject to the availability of fertilizer research funds.
Research Focus
Projects funded by this Request for Proposals must further the understanding of the interaction of fertilizers, agricultural amendments, agricultural minerals, or lime products with the protection of ground or surface water quality in Oregon. Project outcome must be transferable to industry advisors, consultants, and the end users of fertilizer, agricultural amendment, agricultural mineral, or lime products.
The Walser Foundation
Every car you buy or service at Walser fuels something bigger.
A portion of every sale supports the Walser Foundation, funding post-secondary education, career training, and workforce development initiatives. These programs help shape the next generation of innovators and change-makers in the communities we serve.
The Walser Foundation invests in brighter futures through grants, scholarships, and select sponsorships that empower generations with the stability and mobility to shape their own futures and the community around them.
Community Partners Grant
The Walser Foundation accepts grant applications from designated 501(c)3 organizations based in Minnesota and Kansas that focus on post-secondary education and workforce development.
Funding Priorities
The Walser Foundation is focused on existing grant partners in 2026. We are unable to accept new applicant inquiries until 2027. As we shift our giving focus to post-secondary education and workforce development, 2026 is a transition year dedicated to exiting and returning partners. Our giving will be directly aligned with the following areas:
Coachella Valley Mountains Conservancy
Our mission is to protect the natural and cultural resources of the Coachella Valley: the scenic, wildlife, cultural, geologic, and recreational resources that make this such a splendid place for people and all the other life forms with which we share this special place.
The Coachella Valley Mountains Conservancy is a state agency established in 1991 to pursue this mission, and is directed by a 20-member governing board. The Conservancy is an exceptional example of local communities, state elected officials, non-profit organizations, and business and environmental interests working together for the good of all. Since its inception, the Conservancy and its partners have conserved over 106,000 acres.
Proposition 4 Grant Program
The objectives of the Safe Drinking Water, Wildfire Prevention, Drought Preparedness, and Clean Air Bond of 2024 (“Proposition 4”) are to target the most urgent climate needs by investing in preventing devastating wildfires, providing clean, safe drinking water, and boosting water supplies, and protecting California’s iconic landscapes. Proposition 4 project investments aim to assist communities that have been historically underserved by allocating a minimum of 10 percent of available funds to severely disadvantaged communities and a minimum of 40 percent of available funds to disadvantaged communities.
The Conservancy has approximately $11 million available for local assistance grants over the life of its Proposition 4 Grant Program. The minimum local assistance grant amount is $50,000 for implementation projects.
Helpers Community Grants
Helpers Community cares deeply about nonprofits that enrich the lives of individuals with developmental disabilities. Helpers Community is dedicated to supporting nonprofit agencies and individuals that help those who provide residential care, recreation, and job training programs to Adults with developmental disabilities. Helpers Community grants fund 501(c)(3) organizations that serve individuals with developmental disabilities, with priority given to those in the state of California.
Organizations that qualify through their commitment to serve Adults with developmental disabilities can apply for grants for infrastructure and materials for specific programs or projects, including facility improvement projects, but not for general operating support and/or salaries.
The amount of funding requested, keeping in mind our typical grant awards range from $15,000 to $25,000, and if any other potential funders have been approached or have committed to fund a portion of this infrastructure need.
Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.
Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.
How common are grants in this category?
Quite common — grants in this category are more prevalent than in others.
Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?
Most grants are due in the first quarter.
What's the typical grant amount funded for Large Grants for Nonprofit Organizations?
Grants are most commonly $34,887.
Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.
Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.
Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.
Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.
Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.
To improve the chances of receiving large grants, nonprofits should:
Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.
Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.