Best Large Grants for Nonprofit Organizations

New York State Environmental Facilities Corporation

The mission of the Environmental Facilities Corporation is to assist communities throughout New York State to undertake critical water quality infrastructure projects by providing access to low-cost capital, grants and expert technical assistance. A primary goal is to ensure that these projects remain affordable while safeguarding essential water resources. We support this mission by consistently using an innovative approach to developing and advancing new financing strategies to maximize the funding that can be made available to our clients, aiding compliance with Federal and State requirements, and promoting green infrastructure practices.

EFC has broad knowledge and a breadth of experience as a national leader in the municipal bond market. Our distinction gives our partners significant advantages in funding projects: Low cost of capital through grants, low interest rates and reduced bonding costs; Multiple funding options to fit your needs through project planning to construction and completion; Expert support to guide you through the application process and help you comply with state and federal requirements. We ensure the participation of minority-, women-, and service-disabled, veteran-owned businesses through every stage of the construction process. We also partner with a wide variety of professional organizations

Strengthening Essential Cybersecurity for Utilities and Resiliency Enhancement (SECURE) Implementation Grant

EFC is offering $2.5 million dollars to strengthen cybersecurity readiness and resilience and support operational continuity for eligible water and wastewater systems across New York State. The SECURE program will provide funding for projects that enhance cyber protections, modernize digital infrastructure and reduce vulnerabilities for critical drinking water and wastewater systems. This strategic initiative expands upon Governor Hochul’s commitment to safeguard essential services, improve risk management practices, and support communities meeting evolving cybersecurity expectations. Funding is available for both cybersecurity assessments and implementation based on best practices and regulatory requirements. 

The SECURE Implementation Grant will fund deployment and enhancement of cybersecurity controls, technologies, and response capabilities identified during the assessment phase. The funded activities will be in response to a submitted cybersecurity assessment of the system. Completion of a prior assessment using a SECURE Assessment Grant is not required to apply; however a comparable assessment of the system’s cybersecurity needs must have been completed prior to applying for a SECURE Implementation Grant. A municipality may apply for up to 20% of net eligible costs, up to $100,000. 

The RMEF Grant Program lies at the core of advancing our mission.

RMEF established the program in 1986 to provide financial and logistical support to projects that align with our priorities and goals. Grant funds raised by RMEF members, volunteers and generous donors from across the country translate into significantly more conservation accomplishment when matched with partner funds. The RMEF Grant Program also aims to build recognition for RMEF’s work, grow engagement, and boost local fundraising efforts.

Governed by clear guidelines and criteria, the RMEF Grant Program seeks to foster meaningful collaborations and long-term impacts in the conservation of natural resources and outdoor traditions. Grant project partners include federal, state, local, and tribal wildlife and land management agencies, private landowners and local stakeholders, sportsmen and women, and conservation organizations, universities, foundations and the outdoor industry. Eligible projects primarily focus on habitat stewardship, land conservation and access, wildlife management, and hunting heritage.

We support organizations recognized by the Internal Revenue Service (IRS) as a 501(c)3 entity, federal, state, local, or tribal government entities, sportsmen’s organizations, or educational institutions. All applicants must have a Federal Employer Identification Number (EIN) issued by the IRS. RMEF does not offer grants to individuals.

Hunting Heritage

Ensuring our hunting heritage is central to RMEF’s mission. Hunters—America’s first conservationists—remain the driving force behind wildlife conservation. RMEF funds hunting heritage and conservation education to help more people experience the outdoors, learn the skills of hunting, and carry forward the traditions that define big game country, including outdoor skills programs/events, hunter or conservation outreach, mentored hunts, and other similar activities.

The Community Foundation of Abilene offers the Future Fund Grants to support 501(c)(3) nonprofit organizations in Abilene that serve children and youth. Since 1985, the foundation has awarded over $100 million in grants, aiming to enhance the quality of life in the region. Eligible organizations must comply with previous grant reporting requirements and can propose innovative projects that align with the foundation's mission to uplift the community.

The New Mexico Department of Game and Fish's Share with Wildlife Program, established in 1981, aims to support wildlife species lacking other funding sources through tax-deductible donations. It finances projects focusing on research, habitat enhancement, education, and rehabilitation, primarily funded by state income tax check-offs and donations. This program maximizes support for New Mexico's wildlife by leveraging matching federal funds and promoting awareness through license plate sales.

The Nicholas B. Ottaway Foundation offers grants through its Education Committee to support programs enhancing educational opportunities for economically disadvantaged students. These grants focus on initiatives like tutoring, college preparation, and internship programs. To qualify, organizations must be tax-exempt under 501(c)(3). Preference is given to projects that provide ongoing support to students post-graduation, particularly in specific geographic areas such as San Diego County and the New York Metropolitan Area.

The Memorial Foundation for Children Grant Program aims to enhance the lives of children in the Richmond Metropolitan Area by funding nonprofit organizations focused on Education and Health and Wellness. Prioritizing evidence-based programs, it supports initiatives that demonstrate long-term impact and serve low-income families. Grants are awarded biennially, emphasizing collaboration among organizations to tackle significant issues affecting children from birth to age 21. The program seeks to ensure that all children can reach their full potential.

2025 Urban & Community Forestry Natural Disaster and Recovery Supplement

The scope of this program is designed to improve and reestablish urban forests in 56 peninsular Florida counties that were negatively impacted by Hurricanes Idalia, Helene, and Milton. These efforts will emphasize not just tree planting but also pruning and efforts to enhance urban forest resiliency through strong planning methods. The primary purpose is to not just replace lost canopy, but to ensure that the urban forest is more resilient to future storms, enhancing the likelihood of long-term recovery. The State of Florida anticipates an allocation of $1,500,000 to applicants through this funding opportunity.

The Ottauquechee Health Foundation Community Grants aim to enhance health and well-being for residents in core towns through financial assistance and support. Grant applications are accepted on a rolling basis, focusing on mental health, food insecurity, and community care. Organizations eligible for funding include nonprofits with 501(c)(3) status or public entities. By addressing wellness needs, these grants foster partnerships that improve healthcare access and promote lasting community health.

Charter Oak Federal Credit Union's Community Giving Grants Program supports non-profit organizations focused on economic development and social well-being in New London and Windham counties. Grants prioritize initiatives in education, health, human services, housing, community development, and the arts. Eligible organizations must be 501(c)(3) tax-exempt entities serving these communities. The program reviews applications quarterly, with funding awarded to projects that demonstrate a significant community impact and address critical local needs.

The Valley View Foundation Grant aims to enhance the health and wellness of residents in Ada and Pontotoc County, Oklahoma. Funded projects may include hospital infrastructure, immediate health needs, and healthcare education. However, grants are not available for individuals, endowments, or direct scholarships. The foundation particularly prefers organizations focused on community health initiatives, ensuring a positive impact on local residents' well-being.

The New Jersey Highlands Coalition offers emergency funding grants up to $5,000 for grassroots organizations working to protect the region's vital natural and cultural resources. These grants support projects that enhance the Highlands Regional Master Plan, advocate for environmental protection, and educate the public on conservation. Organizations with an operating budget under $200,000 and current Coalition membership are eligible to apply, ensuring support for impactful local initiatives.

The New Jersey Highlands Coalition offers Small Grants up to $5,000 for grassroots organizations focusing on enhancing and protecting the natural and cultural resources of the New Jersey Highlands. These grants support projects that contribute to the Highlands Regional Master Plan, promote environmental protection, and raise public awareness. Organizations applying must have an operating budget under $200,000 and be current Coalition members. The aim is to foster sustainable resource management and community engagement in the Highlands.

About the Indiana Department of Veterans Affairs

The Indiana Department of Veterans Affairs (IDVA) is a state agency dedicated to serving. Its mission is to Support, Serve, and Advocate for the Indiana Veterans Community. IDVA aims to make Indiana the choice for veterans to Live, Work, and Thrive. 

Grants for Veterans’ Services (GVS)

The Indiana Department of Veterans Affairs is seeking applications for the Grants for Veterans’ Services program. This solicitation is open to non-profit organizations registered with the Indiana Secretary of State.

The grant amounts will be between $10,000 and $75,000, depending on each applicant’s need for funds, the availability of funding, and the volume of eligible applicants.

All applications, procedures, and documentation should follow the Indiana Code, Indiana Administrative Code, and Indiana Department of Veterans Affairs’ policies.

Grants for Veterans’ Services may be utilized to provide the following services to caregivers and family members:

• Programs focused on eliminating homelessness, preventing near-term homelessness, and providing safe and secure living conditions.
• Assisting veterans in moving from public housing assistance programs to:
• home ownership, or
• stable, long-term rental status.
• Assisting veterans or an eligible person in finding and using available federal and state resources.
• Providing therapeutic services.
• Providing job training and job search assistance.
• Preventing veteran suicide or the suicide of an eligible person.

The Charlotte Martin Foundation prioritizes funding for rural BIPOC organizations focused on youth programs, emphasizing education, athletics, and cultural expression for ages 6-18. Grants support initiatives that enhance access to diverse experiences, educational opportunities, and sports programs. The foundation is committed to addressing inequities in funding distribution, ensuring resources reach non-dominant communities. Organizations must be based in the Western states and demonstrate a commitment to racial equity and diversity in their leadership and programming.

The Anne Arundel County Forestry and Forested Land Protection Grant Program, in partnership with the Chesapeake Bay Trust, aims to fund forestry projects and land protection initiatives in Anne Arundel County. This program focuses on cost-effective reforestation and greening efforts to enhance protected forested land, improve soil and water quality, reduce erosion, and provide essential ecological services. By supporting these initiatives, the program contributes to environmental sustainability and climate resilience.

The Residential Septic System Education & Maintenance Program, initiated by the Western Montana Conservation Commission, aims to enhance water quality in Western Montana by reducing pollutants from septic systems. This program provides grants for education, outreach, and best practices in septic maintenance. Eligible applicants include government entities and non-profits that meet specific criteria. Projects must focus on outreach, education, and community involvement to foster long-term behavior change regarding septic system care and water quality preservation.

Indiana Office of Community and Rural Affairs

The Indiana Office of Community and Rural Affairs works with Indiana communities to build relevant and economically thriving places where people want to live, work and grow.

Mission: The Indiana Office of Community and Rural Affairs works with local, state and national partners to provide resources and technical assistance to aid communities in shaping and achieving their vision for community and economic development.

CDBG Planning Grant - Environmental Assessment Plan

The Planning Grant Program leverages Community Development Block Grant (CDBG) funding from the U.S. Department of Housing and Urban Development to encourage communities to plan for long-term, holistic improvement. The Office of Community and Rural Affairs (OCRA) seeks applications from local units of government for programs funded through the State CDBG program. Eligible local units of government are counties, cities, or incorporated towns not located within an entitlement community. Unincorporated areas must apply through the county in which they are located. Eligible planning activities consist of all costs associated with data gathering, study, analysis, and preparation of plans and the identification of actions to implement such plans.

Environmental Assessment Plan evaluates potential environmental impacts of proposed projects and identifies measures to avoid, minimize, or mitigate adverse effects on air and water quality, biodiversity, land use, and community well-being. 

The Empowering Adair County Grant supports community betterment projects in Adair County, focusing on tourism, public services, economic well-being, and arts and culture. Established by the Empowering Adair County Foundation in 2005, it aims to enhance the quality of life across all communities in the area. Grants are available for 501(c)(3) organizations and government units, promoting collaboration and leadership to foster sustainable community development.

The SK27 Sickle Cell Initiative Continuation Solicitation, administered by the Ohio Department of Health, aims to enhance the quality and accessibility of comprehensive sickle cell services across Ohio. This initiative focuses on supporting individuals of all ages, promoting public awareness, and improving coordination of resources. By collaborating with Regional Sickle Cell Projects, the program emphasizes effective tracking, counseling, and education to address sickle cell-related health disparities and improve outcomes for affected communities.

The Allianz Life Insurance Company's Financial Stability Grant aims to reduce barriers to economic inclusion by supporting nonprofit organizations that enhance financial stability for low- to moderate-income families. With grants ranging from $50,000 to $75,000, this program prioritizes groups that serve diverse communities, promote equity, and collaborate with local organizations. By focusing on basic needs such as food, shelter, and affordable housing, Allianz is committed to fostering sustainable economic independence within the Twin Cities metro area.

The Youth Philanthropy Board Grant in New Castle County aims to provide crucial support to nonprofits focusing on mental health initiatives for vulnerable populations, including those facing food insecurity, substance abuse, or suicide risks. Targeted groups include LGBTQIA youth, teenage parents, and youth in foster care. Through this initiative, the grant seeks to foster community resilience and enhance the well-being of at-risk individuals in the area.

Mission & Vision

Rochester Area Community Foundation, in partnership with generous philanthropists and community partners, works to improve the quality of life for people who live and work in the eight-county region through its leadership and strategic grantmaking.

Our Mission:

We are cultivating a thriving Greater Rochester region — powered by philanthropy, grounded in community, and sustained across generations.

Our Vision:

We envision a Greater Rochester region transformed by enduring philanthropy, where every person, neighborhood, and future generation can thrive.

Elvira Caroselli Creative Spirit Award

Purpose of Scholarship

The Elvira Caroselli Creative Spirit Award will provide small awards to encourage the creative spirit and endeavors of junior and senior high school students.

Number and Size of Awards

Number of recipients and award amounts vary; paid in one lump sum in the Summer. Maximum award $1,500.

Donor Information

Mrs. Caroselli loved creating, designing, and experimenting. This remarkable woman dropped out of school in the eighth grade to help support her family. Despite a lack of formal education, she sold an invention to a major manufacturer when she was 70 years old.

The Edgar A. Thurman Charitable Foundation for Children provides financial support to 501(c)(3) organizations serving needy children in Virginia, particularly in the Western region and Roanoke Valley. Grants typically range from $3,000 to $10,000 for first-time applicants, while returning grantees may receive up to $20,000. Eligible organizations must demonstrate a commitment to the welfare and education of children, ensuring compliance with all grant conditions.

The HICAHS Emerging Issues Grants support innovative research addressing urgent agricultural health and safety concerns. Funded by the High Plains Intermountain Center for Agricultural Health and Safety, these grants prioritize projects that tackle emerging health risks, including climate change impacts, infectious diseases, and mental health issues among agricultural workers. Applications are accepted on a rolling basis, enabling quick responses to pressing needs in the community. This initiative aims to enhance safety and resilience in the agricultural sector.

About Us

Agriculture has a rich history in Connecticut and plays a major role in our state’s economy. The Department of Agriculture (DoAg) is dedicated to protecting this legacy.

Through thoughtful and comprehensive programs, we foster a healthy economic, environmental, and social climate for agriculture in CT. We manage programs to:

• Develop, promote, and regulate farms and businesses
• Protect agricultural and aquacultural resources
• Enforce laws for domestic animals
• Promote understanding of agriculture’s diversity, cultural heritage, and contribution to CT’s economy

Local Food Purchase Assistance Grant

A statewide grant program funded through S.A. 25-1 to improve local food access and agricultural supply chain resiliency. To learn more check out the press release below.

The purpose of CT DoAg’s LFPA grant program is to provide CT Grown farm products to underserved communities, at no cost to the individual, while maintaining and improving the CT agricultural supply chain resiliency. This is done through:

Establishing and strengthening partnerships across the food supply chain to ensure access to fresh, nutritious, culturally appropriate food in underserved communities.*

Purchasing from small ** Connecticut producers to build and expand market access and opportunities.

CT DoAg has a total of $1,550,000 available to award through a competitive grant process. The selected applicant pool shall be considerate of geography and reach to ensure distribution and sourcing throughout the state.

Funding for the 2026 LFPA Grant is provided by the State of Connecticut in Special Act 25-1 through the Budget Reserve Fund. 

READY Communities grant program

The READY Communities Funding Collaborative is a new public-philanthropic pilot grantmaking program sponsored by the Pennsylvania Department of Aging (PDA), coordinated by Grantmakers In Aging (GIA), and supported by Pennsylvania’s philanthropic organizations. 

The Collaborative will align state and philanthropic funding to support Pennsylvania’s communities in becoming accessible, inclusive, vibrant places for older adults, people with dementia, and neighbors of all ages.  

The Funding Collaborative will advance Aging Our Way, PA—the Commonwealth’s 10-year Multisector Plan on Aging (MPA). This plan serves as a roadmap for the state to ensure that all Pennsylvanians have the supports they need to age with dignity and independence.  

Grant applicants may propose small-scale, neighborhood-level projects or larger efforts with a regional reach. All projects must align with at least one of the Aging Our Way, PA priority areas listed below:

• Unlocking Access
• Aging in Community
• Gateways to Independence
• Caregiver Supports
• Education and Navigation 

The intention of this pilot grant program is to fund new and innovative programs, support the expansion of existing programs to serve new populations, and/or enhance the delivery of existing programs in new ways. Projects should demonstrate potential for scalability, shared learning, and cross-community benefit.

Examples of Projects That Can Be Funded:

• Hosting a memory café or social connection program
• Developing an intergenerational creative arts program
• Launching a new culturally appropriate community program for addressing end-of-life needs
• Developing or expanding a village, hub, or navigation model
• Scaling a community dementia awareness initiative
• Growing a coalition or multisector partnership to apply for the Age-Friendly Communities designation or improve age-friendly programs and design

Organizations can request $10,000, $25,000, or $50,000. 

The Healthcare Foundation of Northern Lake County Grant aims to enhance healthcare access for low-income residents through targeted programs for the uninsured and underinsured. The foundation prioritizes initiatives that improve program effectiveness, organizational sustainability, and collaboration among local healthcare providers. Grants typically range from $20,000 to $100,000, focusing on strategic areas such as clinical care, linkage to care, and systems capacity building, ultimately fostering better health outcomes in the community.