Best Large Grants for Nonprofit Organizations

The ASTR Targeted Research Area Grant supports projects by scholars focusing on under-represented areas in theatre, dance, and performance studies. This includes research on Asian, African, Latin American, and Middle Eastern disciplines, as well as pre-1900 studies and essential translations. The grant, offering up to $3000, encourages recipients to publish their findings and collaborate with Theatre Survey editors. Eligibility extends to scholars with terminal degrees and graduate students, provided they are ASTR members.

The Leola Osborn Trust Grant provides essential support for mentally disabled and underprivileged children and young adults in Tonkawa, Oklahoma. Established in 1968, the Trust offers grants ranging from $1,000 to $5,000, awarding 1-2 grants annually to charitable organizations that assist individuals under the age of 22. Eligible applicants must be located within 10 miles of Tonkawa, ensuring the local community benefits from this vital funding.

Thomas R. Nickoloff Family Foundation 

Promoting Excellence in Educational Outcomes

The Nickoloff Family Foundation was founded in 2017 with the singular mission of “Promoting Excellence in Educational Outcomes,” primarily focused on New Mexico.

It is our core belief that a quality education provides a gateway to personal fulfillment, achievement, self-respect and rewarding work, for the betterment of the individual, families and society as a whole. Building stronger individuals, families and community is central to our mission of funding and “Promoting Excellence in Educational Outcomes.”

Grants

Grant support is provided by the Thomas R. Nickoloff Family Foundation (the “Foundation”) at the sole discretion and determination of the Foundation Trustee to non-profit, tax-exempt organizations as defined under section 501(c)(3) of the United States Internal Revenue Code. 

Categories of Support

The following categories may serve as a guideline to applicants in determining whether their programs are consistent with the Foundation’s core mission of “Promoting Excellence in Educational Outcomes”.

1) Proven and Effective Educational Programming/Initiatives

• School Based Programs
• After School Programs

2) Academic and Foundation Research Focused on:

• Policy, Programming and Initiatives to Improve Educational Outcomes
• School Safety Initiatives

3) Arts Education Outreach Programs

Organizations may apply once yearly for grant support. Multi-year grants may also be considered but would be structured as one-year grants renewable annually at the sole discretion of the Foundation. Any and all grant funds, if any, awarded by the Foundation to an Organization shall be used solely for the explicit purposes noted in a grant application as use of funds.

The Liberty Mutual Foundation offers discretionary grants to 501(c)(3) organizations, focusing on those that empower low-income youth and young adults. The foundation prioritizes initiatives that align with its strategic framework and serves communities in Greater Boston and select areas in Washington State. Funding is not available for individuals, religious organizations, or those who have received support in the last 12 months, ensuring resources are directed towards impactful community-driven projects.

The Horton PhD Research Grant supports up to three Ph.D. students annually in hydrology and related fields, funded by the Robert E. Horton Fund. It provides a maximum of $10,000 for research and travel, along with $500 for U.S. and Canadian applicants participating in AGU's annual meeting. Eligible students must be active AGU members, enrolled for the award's duration, and meet all application requirements. This grant promotes excellence in hydrological sciences.

The Melanoma Research Resident and Fellowship Grant offers $10,000 to support early-career residents and fellows in conducting clinical or laboratory research focused on melanoma. This grant encourages innovative approaches to understanding prevention, detection, and treatment of melanoma, including special emphasis on ocular melanoma. Eligible candidates must have a qualified mentor and conduct research at a U.S. institution. This initiative aims to enhance the landscape of melanoma research and foster the next generation of researchers.

The Women's Fund of Central New York, established in 1998, empowers women and girls through grants and initiatives, promoting their advancement and full participation in the community. With a commitment to diversity and inclusion, the fund supports innovative projects that address key challenges faced by women and girls in Central New York. By fostering collaboration and community engagement, the Women's Fund aims to create a stronger, more equitable society for all.

The Environmental Preservation & Animal Welfare Grant aims to enhance the natural beauty and animal welfare in North Central Massachusetts. This endowed fund supports initiatives such as habitat restoration, animal rescue, and environmental education. Eligible applicants include tax-exempt nonprofits and municipalities within the region. The grant emphasizes public access to natural areas and promotes humane treatment of animals through advocacy and education, ensuring community engagement in environmental stewardship.

The Harden Foundation Grant supports nonprofit organizations in Monterey County across seven focus areas, including youth, family welfare, health, and arts. The Foundation promotes self-reliance, quality of life improvements, and humane treatment of animals. Eligible applicants must have 501(C)3 status and can seek funding for general support, special projects, and one-time capital grants. However, the Foundation does not fund sectarian programs, endowments, or organizations outside its geographical focus.

The Boren Scholarship offers funding for U.S. undergraduate students to study critical languages abroad, enhancing their linguistic and cultural competencies. The program prioritizes students committed to public service in national security roles and supports immersive experiences in diverse regions, excluding Western Europe, Canada, Australia, and New Zealand. Awards vary based on the duration of study, with amounts reaching up to $25,000 for longer programs. This initiative fosters a deeper understanding of global cultures, vital for U.S. interests.

The Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program, initiated in FY 2001, aims to foster collaboration between State and Federal entities in conserving listed species. This program provides funding for acquiring critical land parcels to support U.S. Fish and Wildlife Service-approved recovery plans. By securing habitats at risk from development, the initiative directly addresses the primary threat to endangered species, ensuring effective and immediate conservation actions.

The Water Conservation and Protection Mini-grant Program, offered by Tampa Bay Water, provides $50,000 in funding for local projects aimed at conserving water and protecting drinking water sources in the Tampa Bay area. Grants ranging from $2,000 to $10,000 support community initiatives such as public awareness campaigns, river cleanups, and educational workshops. This program encourages community involvement in safeguarding our vital water resources for future generations.

The Aquatic Weed Control Program in North Carolina aims to assist local governments and residents in managing noxious aquatic weed infestations. By promoting education and partnerships, the program seeks to mitigate economic and environmental impacts from these invasive species. It offers resources for both public and private lands, including technical assistance and financial support for effective management strategies. Through these efforts, the program strives to enhance the health of North Carolina's waterways.

The Alternative Water Supply Grant, supported by Governor DeSantis and the Florida Legislature, allocates $230 million since Fiscal Year 2019-20 to enhance Florida's water systems. This funding emphasizes regional projects addressing critical needs and maximizing benefits, such as reclaimed water, aquifer recharge, and water conservation. Local cooperators must collaborate with their Water Management District to propose projects, which, upon approval, will be submitted to the DEP for funding consideration.

Wisconsin Forest Landowner Grant Program

The Wisconsin Forest Landowner Grant Program (WFLGP) is a cost-share program offered by the Wisconsin Department of Natural Resources (DNR). It is designed to assist woodland owners in protecting and enhancing their woodlands. This program reimburses woodland owners up to 50% of the cost of eligible practices.

Teams to Promote Aging in Place in OMH Supportive Housing (TPAP) 

Request for Proposals

The purpose of “Teams to Promote Aging in Place in OMH Supportive Housing or TPAP” Geriatric Demonstration Project is to facilitate supportive housing residents aging in place based on their priorities and preferences who are age 55 years and older, as well as residents younger than 55 years living with complex medical conditions that necessitate homecare. Older adults living in OMH supportive housing are at risk of losing community tenure due to emerging unmet care coordination, cross service system navigation, and homecare needs compounded by lack of connection to social determinants of health (SDOH) resources, and community and natural supports. Grant funding will support an enhanced home care rate, provision of at least one paid peer professional, and enhanced care coordination with the local office for aging and community partners that addresses social determinants of health and social engagement needs. OMH supportive housing residents identified as at risk for losing community tenure will be supported by an interdisciplinary care team of (1) an OMH supportive housing case manager, (2) a local office for aging case manager, (3) a homecare professional, and (4) at least one mental health or substance use/gambling peer professional who will collaborate with the residents to identify outstanding service and social needs. This will build a person-centered, holistic plan that is based on the older adult’s priorities and preferences for aging in place. A peer professional in this RFP is defined as a person certified, or provisionally certified, as a mental health Peer Specialist through the New York Peer Specialist Certification Board or a person certified, or provisionally certified, as a substance use/gambling Recovery Peer Advocate through the New York Certification Board. Grantees will also be required to collaborate with community-based organizations across service systems, including mental health, aging, substance use, and gambling harms, that also address social determinants of health and social engagement needs, such as, but not limited to, Social Care Networks, Rural Health Networks, Cornell Cooperative Extension, Older Adult Rural Support Program, Regional Economic Development Councils, or Downtown Revitalization Initiatives. This may include projects focused on community inclusion, the Dwyer Veterans Peer-to-Peer Support Program, club houses, OASAS and OMH recovery centers, older adult centers, faith-based, civic, arts, cultural organizations, etc. To foster sharing of best practices in meeting the holistic needs of OMH supportive housing residents, grantees and their partners will participate in virtual and in-person learning collaboratives that include crossdisciplinary training curriculum consisting of trainings chosen in consultation with the chosen grantees and the Geriatric Interagency Mental Health Substance Use Disorder Planning Council and the Master Plan for Aging advisory groups.

Wrap around funding will be available to provide services and goods not covered through existing reimbursement channels that support aging in place in OMH supportive housing. Examples include, but are not limited to, non-medical transportation, memberships to community groups and/or gyms, continuing education, supplies to support personal interests and hobbies, large print calendars, pill containers, and mobility aids. Wrap-around funding can also be used to provide technological support based on the residents’ needs and preferences. Examples include equipment (laptops, computers, personal devices, and/or internet access), online communities and devices to support engagement (Virtual Senior Centers, GetSetUp, Discover Live interactive virtual tours, animatronic pets, and online support through self-help and peer support groups), and technology literacy classes (for email, video chats with friends, children, grandchildren, etc., banking, patient portals, and education on fraud protection) are additional supports to help people use technology to age in place.

This RFP can be used to expand or enhance existing aging programs in OMH supportive housing or can be used to develop a new program that meets all the program requirements. OMH CR-SROs awarded the “Aging in Place Pilot” grant MH253015 may also apply for this grant for their supportive housing programs.

All types of proposals will be evaluated using the same criteria and applicants must identify the geographic designation they will serve, rural or non-rural. Rural counties in NYS are listed in the table below.

The Clean Water Workforce Capacity Development (CWWCD) Block Grant, administered by Watersheds United Vermont, aims to enhance the capabilities of clean water organizations in Vermont. This funding promotes equitable access for under-resourced entities to engage in essential clean water projects. The grant supports activities that foster community engagement, streamline administrative processes, and cultivate a diverse workforce in clean water project management, ultimately leading to increased effectiveness and impact in local clean water initiatives.

The Schreiber Foods Foundation Grant supports charitable organizations addressing food insecurity and basic needs in Wisconsin. Open year-round, it encourages nonprofits in Brown, Calumet, and surrounding counties to apply for funding, which typically ranges from $1,000 to $100,000. The foundation prioritizes innovative solutions that enhance community quality of life, promote self-sufficiency, and foster partnerships. Notably, it does not fund religious activities, individuals, or debt retirement, ensuring a focus on impactful community projects.

Oregon Department of Transportation

The Oregon Department of Transportation began in 1913 when the Oregon Legislature created the Oregon Highway Commission to "get Oregon out of the mud."

Today, we develop programs related to Oregon’s system of highways, roads, and bridges; railways; public transportation services; transportation safety programs; driver and vehicle licensing; and motor carrier regulation.

Mission statement: ​We provide a safe and reliable multimodal transportation system that connects people and helps Oregon's communities and economy thrive.

Safe Routes to School Programs

“Safe Routes to School” refers to efforts that improve, educate, or encourage children safely walking (by foot or mobility device) or biking to school. The Oregon Department of Transportation has two main types of Safe Routes to School (SRTS) programs: Construction and Education and technical assistance. Construction programs focus on making sure safe walking and biking routes exist through investments in crossings, sidewalks and bike lanes, flashing beacons, and the like. Education programs focus on education and outreach to assure awareness and safe use of walking and biking routes.

Safe Routes to School Construction Program

The Safe Routes to School Construction Program provides grant funding for cities, counties, tribes, transit districts, and the state through a reimbursement process for investments that address barriers to students walking and biking to school.

Program Description

The Safe Routes to School Construction Program is housed in the Public Transportation Division and divided into three types of grants: Competitive Construction Grants; Rapid Response Constructions Grants; and Project Identification Program (Planning Assistance).

Grant cycles will be every two years starting in 2019. All subsequent funding cycles will be determined by the Safe Routes to School Advisory Committee and the Safe Routes to School Construction Program Manager.

Competitive Construction Grants

87.5 percent or more of Safe Routes to School funds will be set aside to build street safety projects to reduce barriers and hazards for children walking or bicycling to or from schools. Funds will be distributed through an application-based, competitive, process every two years.

All projects must have at least 40% local cash match for the Competitive Construction Grant Program. Projects may qualify for a reduced 10.27% or 0% local cash match if certain criteria are met.

Commitment to Outreach

Applicant must commit to completing a minimum amount of outreach informing the community about the new construction project and how to use it safely.

Focus Area

Project will primarily affect students at a Title I school as defined as a school where 40% or more students are low income including data sets to address transportation disparities. 

Oregon Department of Transportation

The Oregon Department of Transportation began in 1913 when the Oregon Legislature created the Oregon Highway Commission to "get Oregon out of the mud."

Today, we develop programs related to Oregon’s system of highways, roads, and bridges; railways; public transportation services; transportation safety programs; driver and vehicle licensing; and motor carrier regulation.

Mission statement: ​We provide a safe and reliable multimodal transportation system that connects people and helps Oregon's communities and economy thrive.

Safe Routes to School Programs

“Safe Routes to School” refers to efforts that improve, educate, or encourage children safely walking (by foot or mobility device) or biking to school. The Oregon Department of Transportation has two main types of Safe Routes to School (SRTS) programs: Construction and Education and technical assistance. Construction programs focus on making sure safe walking and biking routes exist through investments in crossings, sidewalks and bike lanes, flashing beacons, and the like. Education programs focus on education and outreach to assure awareness and safe use of walking and biking routes.

Safe Routes to School Construction Program

The Safe Routes to School Construction Program provides grant funding for cities, counties, tribes, transit districts, and the state through a reimbursement process for investments that address barriers to students walking and biking to school.

Program Description

The Safe Routes to School Construction Program is housed in the Public Transportation Division and divided into three types of grants: Competitive Construction Grants; Rapid Response Constructions Grants; and Project Identification Program (Planning Assistance).

Grant cycles will be every two years starting in 2019. All subsequent funding cycles will be determined by the Safe Routes to School Advisory Committee and the Safe Routes to School Construction Program Manager.

Rapid Response Constructions Grants

Up to 10 percent of Safe Routes to School funds will be available for urgent needs or systemic safety issues. Funds will be distributed through an application process that is open as long as there are funds available.

The ODOT Safe Routes to School Rapid Response Construction Grant Program funds projects that are eligible for the Competitive Construction Grant program and meets unique eligibility requirements. Road authorities are encouraged to apply for urgent projects that address barriers for students walking and biking to school. Most eligibility requirements for the Rapid Response Grants are the same as the Competitive Construction Grants. However, some added eligibility requirements are unique to the Rapid Response Grant Program.

• Be an Urgent Safety Need or Opportunity: Project must include proof of circumstances that trigger an urgent safety need or urgent opportunity that cannot wait until the next Safe Routes to School Infrastructure Competitive Grant Program which runs every two years. 

Oregon Department of Transportation

The Oregon Department of Transportation began in 1913 when the Oregon Legislature created the Oregon Highway Commission to "get Oregon out of the mud."

Today, we develop programs related to Oregon’s system of highways, roads, and bridges; railways; public transportation services; transportation safety programs; driver and vehicle licensing; and motor carrier regulation.

Mission statement: ​We provide a safe and reliable multimodal transportation system that connects people and helps Oregon's communities and economy thrive.

Safe Routes to School Programs

“Safe Routes to School” refers to efforts that improve, educate, or encourage children safely walking (by foot or mobility device) or biking to school. The Oregon Department of Transportation has two main types of Safe Routes to School (SRTS) programs: Construction and Education and technical assistance. Construction programs focus on making sure safe walking and biking routes exist through investments in crossings, sidewalks and bike lanes, flashing beacons, and the like. Education programs focus on education and outreach to assure awareness and safe use of walking and biking routes.

Safe Routes to School Construction Program

The Safe Routes to School Construction Program provides grant funding for cities, counties, tribes, transit districts, and the state through a reimbursement process for investments that address barriers to students walking and biking to school.

Program Description

The Safe Routes to School Construction Program is housed in the Public Transportation Division and divided into three types of grants: Competitive Construction Grants; Rapid Response Constructions Grants; and Project Identification Program (Planning Assistance).

Grant cycles will be every two years starting in 2019. All subsequent funding cycles will be determined by the Safe Routes to School Advisory Committee and the Safe Routes to School Construction Program Manager.

Project Identification Program (Planning Assistance)

Up to 2.5 percent of Safe Routes to School funds will be used by the Oregon Department of Transportation to help communities identify projects that reduce barriers and hazards for children walking or bicycling to and from school and that will lead to eventual construction.

Consultant services will be provided for up to 30 school communities each cycle depending on funding availability.

Consultant services will assist the community (school representatives, school community, and local road authority representative) to identify construction needs near one school, a cluster of schools feeding into the same middle or high school, or all schools in a community of 10,000 or less, focusing on all streets within a quarter-mile of the school, as well as critical issues within a mile of the school.

Consultant will coordinate and implement the Project Identification Program process in each community for each school. The outcome of each Project Identification Program process will be a Safe Routes to School Plan for each school, cluster of schools, or small community that outlines construction and educational needs to address barriers to students walking and biking to school and provides some information needed to apply for the ODOT Safe Routes to School Grants. 

The intent of the Project Identification Program is to assist communities in planning for Safe Routes to School who are unable to due to lack of funding, capacity, or expertise.

The Desert Conservation Program, administered by the California Wildlife Conservation Board, aims to protect and restore the Mojave and Colorado Deserts, which are vital for biodiversity and cultural heritage. This initiative, established through the California Desert Conservation Act, focuses on land acquisition, restoration, and enhancing public access while also addressing climate resilience and improving air and water quality. Eligible projects include habitat restoration and scientific studies to support endangered species recovery.

The Aging and Adult Services: Emergency Solutions Grant Program aims to support non-profits and local government agencies in providing services for individuals and families experiencing homelessness or at risk of homelessness in North Carolina. Funded by the NC Department of Health and Human Services, this program focuses on crisis response and housing solutions to ensure homelessness is rare and brief. Activities include improving emergency shelters and offering essential services to those in need.

The Ohio Environmental Protection Agency's Targeted Brownfield Assessment (TBA) Program offers essential property assessment services at no cost to local government entities. This program is designed to minimize contamination uncertainties for brownfield sites, facilitating cleanup and redevelopment efforts. Eligible applicants include counties, cities, and non-profit organizations. TBA services, such as Phase I Environmental Site Assessments and remedial action plans, support real estate transactions and funding applications, ultimately transforming blighted properties into valuable community assets.

The Emergency Solutions Grant (ESG) Program, offered by the Missouri Housing Development Commission, aims to provide essential housing assistance to homeless or nearly homeless individuals in Missouri. With an anticipated funding of up to $2,858,041, the program prioritizes activities like rapid re-housing, street outreach, and homelessness prevention. The competitive allocation process ensures funds are effectively used to support community initiatives that stabilize housing and prevent homelessness, aligning with HUD regulations.

The Montana Nita M. Lowey 21st CCLC Grant provides essential funding for Local Educational Agencies and community organizations to enhance academic enrichment opportunities for students during out-of-school time. With a minimum award of $50,000 per year for five years, this grant supports programs that reinforce regular academic activities and foster literacy and educational development, ultimately aiming to improve outcomes for students and families in the community.

Patterson Family Foundation

The Patterson Family Foundation was established to reinvest in rural communities and cultivate values of education and hard work for current and future generations. Currently, the Foundation is led by the adult children of the Patterson Family.

The Patterson Family Foundation, based in Kansas City, Missouri, is a family-led foundation that extends the legacy of Neal and Jeanne Patterson. The Foundation’s mission, “Working together to help rural communities thrive,” is carried forward through strategic grantmaking and other collaborative initiatives that serve rural counties across Kansas and western Missouri. 

Where We Serve

We are geographically focused on assisting Kansas and western Missouri counties with fewer than 50,000 residents.

Our impact is realized through four interconnected priorities:

Economic Opportunity

• Our vision: Rural communities have resilient economies that offer diverse and stable career opportunities for all residents.
• We are committed to keeping rural economies strong by helping grow and retain great talent, attracting former and new residents, and investing in opportunities that strengthen and diversify local and regional economies

Education

• Our vision: All students receive a high-quality education that prepares them for future success.
• A strong education system is at the heart of a thriving community, and we’re working alongside educators, families, and local leaders to help it grow. This means supporting and developing exceptional teachers, providing students with opportunities to develop skills and experience, and creating more hands-on learning opportunities that prepare students for the future.

Healthcare

• Our vision: Communities have access to high-quality healthcare services, leading to improved health outcomes and increased well-being for all residents.
• Access to quality healthcare is essential for keeping rural communities strong. We work to expand the healthcare workforce, improve access to essential services, and empower all rural residents to lead long, healthy lives.

Community Engagement

• Our vision: Residents are actively engaged in decision-making process, contribute to community development, and have a strong sense of belonging and purpose.
• Strong communities are built through local leadership, volunteerism, and collaboration. We work alongside communities to drive grassroots engagement and empower multi-generational leaders. Through regional partnerships and strong community foundations, we help communities deepen relationships, expand opportunities, and steward local resources for future generations.

Open Call Grants

Patterson Family Foundation’s Open Call Grants are publicly announced and submitted through the Grants Portal. Applications are reviewed using criteria aligned with the Foundation’s priorities, including community impact, feasibility, sustainability, and readiness to implement the proposed work in the Kansas or western Missouri rural community. 

Open Call Grant: Adult Learning

This opportunity supports adult learners in building literacy, workforce readiness, and lifelong learning skills. Funding helps reduce barriers to participation and expands equitable access to evidence-based education that prepares adults for meaningful employment, civic engagement, and personal advancement. Projects should strengthen community-based programs, support innovation, and align adult learning with local workforce needs, with priority given to organizations in our rural catchment area or partnering with local employers. Applicants should plan to report on learner participation, skills or credentials gained, employment or career advancements, and partnerships that connect adult learners to local opportunities. 

Eligible uses of funds include:  

• Funding for new instructors and staff training 
• Instructional materials 
• Technology and digital learning tools 
• Outreach and recruitment 
• Support services that reduce participation barriers 
• Program evaluation and data collection