Best Large Grants for Nonprofit Organizations

Curtis Marvin Hohn Endowment

To provide financial support to South Dakota students attending an in-state institution of higher learning and that demonstrate a commitment to public service.

Applicants for the Curtis Marvin Hohn Legacy Scholarship will reflect the values that embodied Curt Hohn's life. These characteristics may include, but are not limited to:

• Personal integrity, individual character, and courage
• Leadership in school and community
• Demonstrated involvement in civic affairs
• Participation in organizations that shape the school and community
• Individual leadership to reform policies that benefit the public good of the school and community
• Demonstrated work ethic in the school and community
• Demonstrated interest in national and global issues that impact the public interest
• Demonstrated interest in humanitarian issues

This scholarship was established to celebrate the life and accomplishments of Curtis M. Hohn, a prominent figure in South Dakota's water policy landscape, renowned for his service as a public servant, community activist, and leader. Curtis held several key positions, including serving on the staff of U.S. Senator George McGovern, directing the United Family Farmers organization, and managing the Oahe Conservancy Subdistrict. He played a crucial role in assessing the Oahe Irrigation Project and negotiating legislative settlements for alternative water projects. Moreover, Curtis led negotiations between the local Oahe Subdistrict with Congress and the U.S. Department of the Interior. Notably, he played a pivotal role in the implementation of South Dakota's first major pipeline project utilizing Missouri River water.

Curt was an avid reader of history. His lifetime commitment of political courage and public service are reflected in the words of Robert F. Kennedy, a man Curt deeply admired and often quoted - "Few will have the greatness to bend history itself; but each of us can work to change a small portion of events, and in the total of all those acts will be written the history of this generation."

The Aaron Straus and Lillie Straus Foundation focuses on enhancing opportunities for Baltimore families through education, health services, and community engagement. Since its establishment in 1926, it has prioritized support for Jewish communities, immigration advocacy, and social innovation. The foundation aims to connect families to resources that foster resilience and growth, ensuring they can thrive in a supportive environment. By investing in local initiatives and emerging leaders, the foundation seeks to create lasting impact in the Baltimore region.

The Vegas Golden Knights Foundation Grant supports local non-profits in Las Vegas, focusing on health and wellness, education, youth sports, and military and first responders. As a 501(c)(3) organization, it aims to make a sustainable impact through community programming and direct grants, awarding up to $20,000 per grant cycle. Eligible organizations must be qualified 501(c)(3) entities and may only submit one application per cycle, ensuring focused support for community-driven initiatives.

The Massachusetts Food Ventures Program (MFVP) aims to enhance access to healthy, affordable food and bolster economic opportunities for low to moderate income communities. By providing grants for food ventures in areas like Gateway Cities and rural regions, MFVP supports local agricultural enterprises and aligns with the Massachusetts Local Food Action Plan. Key investment areas include food processing infrastructure and improved distribution systems, ensuring equitable access to fresh local food and promoting healthy eating.

Mental Health

Overview

Our vision for adults living with mental illnesses is that they are engaged and supported members of the community

We recognize advocacy at the state and federal levels is essential to achieving meaningful change, so we partner with organizations from across the United States to raise awareness of critical mental health issues and to press for increased public funding.

Our Goals

Through our investments and advocacy, we hope to accomplish the following:

• There is a strong, well-trained mental health workforce capable of meeting community need.
• Adults affected by serious mental illnesses have access to high-quality medical treatment and support services that enhance their quality of life.
• Mental health services are well funded by public and private investment.

The Senior Citizens Housing of Ann Arbor (SCHAA) Grant Program, established by the Ann Arbor Area Community Foundation, aims to support organizations and programs that assist older adults and their caregivers. For 2025, the focus will be on technology and transportation initiatives within Washtenaw County. This program reflects the foundation's commitment to community empowerment, equity, and collaboration, ensuring that all residents have access to vital resources and support.

Farm to Food Security Grant Program

The Farm to Food Security (F2FS) Grant Program is a competitive funding opportunity to help individuals and organizations buy foods grown and raised in Minnesota and distribute them at no cost to Minnesotans experiencing food insecurity, particularly individuals whose needs are not met through the traditional emergency food system.

Eligible projects and expenses

All food distributions that are part of F2FS projects must take place in Minnesota, but how the food is shared can be based on the needs of the community.

Examples of eligible projects include but are not limited to:

• A local food shelf buying food produced by farmers in their county and then distributing the food as part of their weekly distribution events.
• A regional hospital establishing a “produce prescription” program to buy local foods and deliver them to families in need and individuals suffering from chronic illnesses.
• A Tribal government buying traditional foods grown by Tribal members and distributing the foods to elders.
• A farmers’ market implementing a food recovery program to pay farmers for products left at the end of the market and partnering with a local food shelf to distribute them.
• Eligible expenses include:
• Foods grown and raised in Minnesota, including whole (unprocessed), minimally processed, and processed items.
• Up to 15% of the total project costs for administrative costs related to food storage, food transportation, and other supporting expenses.

See the request for proposals (RFP) for more details and examples of the types of projects and expenses that are eligible.

The Myron Stratton Home Grant aims to honor Winfield Scott Stratton's legacy by supporting organizations that assist underserved populations, including the elderly, children, and those unable to work due to illness. The grant prioritizes innovative projects that enhance existing services or create new programs to meet community needs in El Paso and Teller counties. Collaborative efforts that prevent service duplication are especially encouraged, ensuring that resources effectively reach those in need.

The Lead-Safe Homes Program (LSHP), managed by the Wisconsin Department of Health Services, is offering grant opportunities to ensure homes are lead-safe for children, starting from October 1, 2025, to September 30, 2026. This initiative aims to partner with local organizations to provide lead hazard reduction services for Medicaid-eligible children and pregnant women. With up to $5 million available, multiple grants may be awarded to enhance children's health and safety across Wisconsin.

The Eastern Bank Foundation (EBF) is dedicated to empowering communities through its Neighborhood Donations initiative. By investing over $16 million in local organizations, EBF aims to support vital services and promote equity in Eastern Massachusetts, Southern New Hampshire, and Rhode Island. This program allows contributions to non-501(c)(3) organizations, reinforcing EBF's commitment to partnership and community-driven solutions, with donations typically ranging from $100 to $1,000.

The Lundbeck US Charitable Fund focuses on enhancing brain health through impactful donations. Established to support organizations dedicated to brain health, it addresses pressing needs by funding innovative strategies and community collaborations, particularly for at-risk populations. The Fund aims to transform lives and improve mental health care, with a commitment to responsible giving. With over 20 organizations supported in 2023, it drives meaningful change in communities affected by brain disorders.

Montana State University was founded February 16, 1893, as one of the nation's original land-grant colleges authorized by the landmark Morrill Act of 1862. Since then, MSU has been dedicated to the mission of education, research and outreach, providing access to life-changing higher education that has the potential to transform lives and communities.

College and Departmental Scholarships

Some of the colleges and departments at Montana State University offer scholarships to students. A limited number are available for incoming students. 

Robert E. Yoblonsky Student Leadership Scholarship

Required Qualifications:

• Pursuing a degree from the College of Arts and Architecture
• Participating in the College of Arts and Architecture Student Ambassador program
• Demonstrate financial need
• Sophomore, junior or senior status

Scopes: Architecture, Art, Arts and Architecture, Film and Photography, Music

The Lundbeck US Charitable Fund focuses on enhancing brain health through sponsorships that support various initiatives. These sponsorships are available to both non-profit and for-profit organizations, provided they align with Lundbeck's mission. Funds are primarily allocated for educational or awareness events, with an emphasis on community outreach and collaboration to address gaps in care, especially for vulnerable populations. By fostering innovative strategies, the Fund aims to drive meaningful change in the field of brain health.

The Aerie Real Foundation™ Community Grant aims to enhance confidence, inclusion, and sustainability among young women while supporting non-profit organizations in the US and Canada. Grants of up to $10,000 are available to programs focused on mental well-being, fostering inclusive communities, and environmental protection. Applications are accepted from certified 501c3 nonprofits, with funding allocated for projects that align with the Foundation's mission. The goal is to empower the next generation and create a positive impact in local communities.

The David J. Morafka Memorial Research Award, established by the Desert Tortoise Council, offers $2,500 to support research on gopher tortoise species in the southwestern U.S. and Mexico. This award honors Dr. David J. Morafka's contributions to herpetology. Applicants must be affiliated with recognized institutions and present their findings at a Desert Tortoise Council symposium. Evaluation criteria include research significance, originality, and feasibility, ensuring impactful conservation efforts.

The Columbus Realtors Foundation supports real estate-related initiatives in central Ohio through its community grants. With over $600,000 invested since 2008, the foundation aids organizations that address homelessness, repair homes for low-income families, and promote affordable housing. Established in 1991, it aims to enhance the real estate environment while empowering local nonprofits and government entities to foster healthy communities.

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Capacity Fund

The NAFC Capacity Fund supports investments that strengthen clinic and pharmacy infrastructure and organizational effectiveness. This funding is designed to help NAFC members build the systems, tools, and capabilities needed to operate more efficiently, improve quality, and expand their ability to serve patients over time.

The Akron Community Foundation's Community Fund for Education Grants focuses on investing in the future of Summit County students. By partnering with local schools and community members, the foundation aims to support programs aligned with the Cradle to Career continuum. Grants target key transition points in education, particularly for early learning initiatives, ensuring children from birth to age five are equipped for success. This holistic approach enhances educational outcomes in the community.

The THCF: Community Grants for Wildlife Conservation supports initiatives across Missouri, encouraging proposals that enhance regional wildlife efforts. Starting in 2024, organizations can apply for funding for up to three consecutive years, promoting sustainability and impactful conservation projects. Eligible applicants include nonprofits dedicated to improving wildlife habitats and conservation strategies. This program aims to foster collaboration and maximize funding impacts to benefit the local ecosystem and communities throughout the state.

Eastern Illinois Foodbank seeks to enhance its network of partner agencies dedicated to alleviating hunger. Organizations must be located within a specified 18-county area and possess 501(c)(3) tax-exempt status, or align with a qualifying umbrella organization. Partners are expected to maintain secure food storage, establish a budget for operational costs, and utilize the Link2Feed electronic system for record-keeping. This initiative ensures effective resource distribution and supports community members in need.

The Public Participation Grants (PPG) program in Washington offers up to $60,000 annually to individuals and nonprofit organizations. Its goal is to enhance public awareness and engagement in the cleanup of contaminated sites while promoting better waste management practices. These grants align with the State's Solid and Hazardous Waste Management Plan, which seeks to reduce waste and manage remaining materials safely. This initiative fosters community involvement in environmental stewardship.

About Legacy Foundation

Legacy Foundation is the community foundation for Lake County, Indiana. We connect people, knowledge, and funding to build an equitable, accessible, and inclusive Lake County, now and for generations to come.

Legacy Foundation is supported by a broad base of individuals, families, and businesses connected by the desire to improve Lake County, Indiana. With a growing portfolio of over 400 funds and approximately $124 million in assets, Legacy Foundation is a trusted source for philanthropic giving in the region.

For over 30 years, Legacy Foundation has been empowering people, providing strategic leadership, and impactful philanthropic support to create an equitable Lake County where all people thrive.

Mission Statement

Transforming Lake County by providing strategic leadership and impactful philanthropic support to ensure equitable opportunity for all communities that we serve.

Vision Statement

Create an equitable Lake County where all people thrive.

Building the Future Vocational Scholarship Application

The Building the Future Vocational Scholarship supports scholarships for Lake County residents to attend a public or private institution to earn a certificate or vocational/trade school degree with the intent to gain local employment.

• Agriculture
• Automotive/Mechanical
• Computer/Technology
• Construction
• Cosmetology/Esthetician/Barbering
• Culinary Arts
• Healthcare (Medical, Dental & Emergency Services)
• IT & Business Services
• Manufacturing/Industrial
• Paralegal/Court Reporter
• Real Estate
• Transportation/Aviation

Legacy Foundation PAYS awards directly to SCHOOLS, NOT students. Payments will be:

• Paid to the school to cover OUTSTANDING tuition costs after all other aid is used (Work One, Pell grant, etc.) AND/OR
• Paid towards costs for required books and/or equipment for the program.

The Gerber Foundation supports youth programs in West Michigan, focusing on projects benefiting children from birth to 18 years. Emphasizing health, nutrition, literacy, and education, grants typically are under $10,000, with an average size of less than $5,000. Collaborative programs are encouraged. The foundation prioritizes initiatives that enhance the quality of life for young children, particularly those in Lake, Muskegon, Newaygo, and Oceana Counties.

Pennsylvania Department of Community and Economic Development

The Department of Community and Economic Development (DCED) works every day to ensure Pennsylvania is a premier state to do business, where we adopt and innovate the next generation of breakthroughs in a diverse mix of industry clusters, where we cultivate a resilient economy, and where we invest in our people and our communities to build a stronger Pennsylvania that works for all the residents, workers, businesses, and entrepreneurs that call our Commonwealth home.

Marketing to Attract Marquis Events (MTAME) / Marquis Events Grant Program

The 2026 Marquis Events Grant Program was established by Tourism Promotion Fund legislation (Act 109 of 2018) and funded by Section 1934-A(e) of Act 45 of 2025 (P.L. 156, No. 45). This program seeks to promote the Commonwealth as a premium host of large-scale events by providing the funds necessary to secure and execute large-scale events at world-class levels. To accomplish this goal, the Office of Tourism will establish a grant program for entities responsible for hosting major events—such as sports tournaments and series, large-format public festivals, multi-day cultural or sports activations, fan zones, or signature celebrations.

Florida Department of Health

Led by the State Surgeon General, the mission of the Florida Department of Health is to protect, promote, and improve the health of all people in Florida through integrated state, county, and community efforts.

The Live Like Bella Pediatric Cancer Research Initiative

The Florida Department of Health’s Live Like Bella Pediatric Cancer Research Initiative supports the pursuit of identifying cures for pediatric cancer.

The Live Like Bella Pediatric Cancer Research Initiative is established in section 381.922, Florida Statutes, works to advance progress toward curing pediatric cancer through grants awarded through a peer-reviewed, competitive process, to:

• Significantly expand pediatric cancer research capacity in Florida
• Improve both research and treatment through greater pediatric enrollment in clinical trials networks
• Reduce the impact of pediatric cancer on disproportionately impacted individuals

Research Focus

Applications submitted in response to this Funding Opportunity Announcement (FOA) must be responsive to one of the following areas of focus. 

• Prevention and Treatment
• Screening
• Obesity
• Treatment-Related Morbidities
• Technology Transfer Feasibility (TTF)
• Investigational New Drug or Investigational Device Exemption

Efforts to foster collaborations among institutions, researchers, and community practitioners should be included, when possible. Preference will be given to applications that address at least one of the cancers listed in the Research Priorities section of this FOA.

Funding Information

Applicants must request funding in the preceding grant categories to pursue research in the areas of focus outlined in the Research Focus section of this FOA. Preference will be given to applications that address the priorities listed in the Research Priorities section of this FOA. Specific grant funding amounts are available for each grant category.

Grant Categories

Applications in response to this FOA must align to a grant category (depending on the grant program) to pursue an area of focus from the Research Focus section of this FOA. Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding. 

The grant categories are: 1) Bridge; 2) Discovery Science; 3) Emerging Therapeutics and Technologies; 4) Equipment; 5) Multicenter Clinical Trials; 6) New Investigator Research (NIR); 7) High-Risk, High-Reward Clinical Research; 8) High-Risk, High-Reward Discovery Science; 9) Non-Typical Clinical Trials/Socio-Behavioral Research; 10) Research Infrastructure

Bella Initiative Grant Categories: Research Infrastructure

Eligible organizations may submit an infrastructure application in at least one of the following six areas: tissue banking, bioinformatics, genomics, diagnostic imaging, disproportionately impacted individuals, or quality indicator systems. The Department is particularly interested in research involving quality indicator systems, when this is linked with other priorities, such as increasing the number of Florida research networks, external funding for research infrastructure, and large-scale projects, including but not limited to National Cancer Institute grants. Organizations will only be permitted to be the lead on one application but may be collaborators on applications submitted by other organizations. When organizations collaborate on more than one infrastructure application, they need to describe how the projects are different and do not overlap.

Applications for research infrastructure grants that are reviewed and assigned exceptional scientific merit will be considered for preferential funding.

The Social & Economic Mobility Grant, offered by the Community Foundation of Broward, supports 501(c)(3) nonprofits providing services in Broward County. Eligible organizations must have a Gold Seal of Transparency from Candid. Grants are awarded twice a year across four focus areas, including Social & Economic Mobility. Specific areas, such as Strong Nonprofit Community, accept applications by invitation only. Detailed eligibility criteria can be found in the Focus Area Grant Guide.

The GSF Foundation Grant supports 501(c)(3) non-profit organizations that enhance the lives of children and families in need. Applications must be submitted by a current GSF Associate who nominates the organization and its project. Since 2002, the foundation has funded over 600 organizations nationwide. It emphasizes personal involvement and contributions from associates, focusing on essential needs such as education tools, food, and shoes for children. Grants are reviewed at local and national meetings.