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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,629 Results based on applied filters

NH: Environmental Quality Incentives Program (EQIP)

USDA: Natural Resources Conservation Service of New Hampshire
Federal Government
New Hampshire
Unspecified amount
The Environmental Quality Incentives Program (EQIP) by USDA's Natural Resources Conservation Service supports farmers and forest landowners in implementing conservation practices. It provides technical and financial assistance to address natural resource issues like soil health, water quality, and wildlife habitat. Eligible applicants include agricultural producers and landowners. EQIP also offers various initiatives, including the Organic Initiative and High Tunnel Initiative, to promote sustainable practices and enhance agricultural resilience.
Agriculture Forestry Water Resource Management +7 more

Hewitt Foundation Grant

Hewitt Foundation
Private
Canada
Unspecified amount
The Hewitt Foundation Grant supports Canadian registered charities focused on health, education, and community development. It emphasizes collaboration to address mental illness, trauma, and research for innovative solutions. The foundation also aids educational institutions and programs that foster inclusivity and support for youth. Additionally, it champions indigenous-led initiatives and environmental conservation, ensuring a better quality of life for all Canadians. Grants are exclusively for registered charities as defined by Canadian law.
Mental Health & Psychiatric Diseases Brain Injuries Educational Access & Equity +14 more

Community Ties Giving Program: Annual Local Grants

Union Pacific Foundation
Corporate
Ada County, Idaho, Adams County, Colorado +177 more
US $5,000 - US $30,000
The Community Ties Giving Program by Union Pacific Foundation offers local grants aimed at enhancing community well-being through diverse funding priorities. These include safety initiatives, workforce development, community vitality, and environmental sustainability. The program emphasizes supporting organizations that promote diversity, equity, and inclusion, aiming to create impactful projects that resonate with Union Pacific's heritage and mission. Eligible applicants must be nonprofit organizations serving Union Pacific communities and demonstrate a clear need and capacity to deliver effective programming.
Library Services Museums & Cultural Institutions Community / Public Safety +22 more

Island Foundation: Environment Grants

Island Foundation
Private
Barnstable County, Massachusetts, Bristol County, Massachusetts +6 more
Unspecified amount
The Island Foundation offers Environment Grants to support projects in coastal regions of Maine, Massachusetts, and Rhode Island, focusing on marine and coastal resource conservation. Priority is given to initiatives addressing climate change, promoting sustainable landscapes, and enhancing community health through environmental conservation. The Foundation encourages 501(c)(3) nonprofit organizations, with a preference for those engaged locally, to apply for funding that strengthens both ecological and community resilience.
Fisheries Marine Biology Marine / Ocean Conservation +8 more

Joe C. Davis Transformational Grant

Joe C Davis Foundation
Private
Davidson County, Tennessee
Unspecified amount
The Joe C. Davis Foundation Grant focuses on supporting charitable organizations that embody core values such as personal initiative, hard work, and education. With an emphasis on education, healthcare, and community services, the Foundation primarily supports initiatives in Nashville, Tennessee. It funds a variety of programs, from K-12 education to healthcare services, and prefers one-time grants that enhance existing programs or create new ones with sustainable financial models.
Workforce Preparation & Job Readiness Youth Services Homelessness Services +20 more

ACCF Community Grant

Allegan County Community Foundation
Private
Allegan County, Michigan
Unspecified amount
The ACCF Legacy Grant aims to support various community initiatives in Allegan County, focusing on youth programs, arts and culture, environmental conservation, economic development, animal welfare, and capacity building for local nonprofits. The grant prioritizes projects that enhance residents' quality of life, promote economic security, and ensure access to essential services. Eligible applicants must be 501(c)(3) organizations in good standing, demonstrating a commitment to sustainable and impactful community solutions.
Economic Services & Development Environmental Conservation Domestic Violence +17 more

Community Development Block Grant Program (CA)

California Department of Housing and Community Development
State/Local Government
California
Unspecified amount
The Community Development Block Grant Program (CDBG) in California offers funding to improve living conditions for low- and moderate-income residents. Grants are allocated for community and economic development projects that address urgent needs, prevent slums, and enhance public services. Eligible activities include housing rehabilitation, public improvements, and economic assistance. With competitive applications capped at $300,000 and specific project limits, the program aims to foster viable urban communities and support diverse community needs.
Economic Services & Development Community Development & Revitalization Waste Management +11 more

Programmatic Funding - Environment Pillar Award

Honda USA Foundation
Corporate
Alabama, California +15 more
US $25,000 - US $100,000
The Environment Pillar Award by Honda supports nonprofit organizations and schools in the U.S. focused on sustainability. Grants aim to reduce environmental impact through programs in decarbonization, clean energy, and efficient resource use. Eligible projects must align with Honda's mission and primarily benefit communities where Honda associates live and work. Organizations can apply for up to two grants, provided they meet specific eligibility criteria, including tax-exempt status under the IRS.
Sustainability Renewable/Sustainable Energy Environmental Conservation +9 more

ECCF Community Grant- Field of Interest Funds

Eau Claire Community Foundation
Private
Chippewa County, Wisconsin, Eau Claire County, Wisconsin
Unspecified amount
The Eau Claire Community Foundation (ECCF) offers the ECCF Community Grant focusing on various areas including arts, education, environment, and social services. This grant aims to support programs that enhance community life, provide educational opportunities, and address essential needs for residents. Organizations located in the Eau Claire area or those demonstrating significant impact are encouraged to apply. The foundation prioritizes innovative proposals that foster collaboration and effectively respond to local needs.
Music Visual Arts Performing Arts +30 more

Green Partners Grants: Environmental Action Program

Minnesota State Government - Hennepin County
State/Local Government
Hennepin County, Minnesota
Up to US $50,000
The Green Partners Grant by Hennepin County aims to empower organizations to foster environmental stewardship among residents. This program provides funding for initiatives that engage both youth and adults in sustainable practices. Key focus areas include waste reduction, composting, and enhancing biodiversity through habitat creation. Three grant types are available: Environmental Action, Youth Environmental Leadership, and Youth Environmental Education. Eligible applicants include schools, nonprofits, and park districts, with funding amounts varying based on previous awards.
Environmental Stewardship Environmental Education Waste Management +6 more

McGowan Charitable Fund Grants

William G. McGowan Charitable Fund
Private
Cook County, Illinois, Eagle County, Colorado +9 more
Unspecified amount
The William G. McGowan Charitable Fund provides grants focusing on Education, Human Services, and Healthcare initiatives. The fund prioritizes programs with measurable outcomes that aim to alleviate poverty and suffering. Eligible organizations must be 501(c)(3) nonprofits and align with the fund's mission to create sustainable change. Applications are accepted by invitation only in specific regions, with a rolling deadline. The fund seeks collaborative efforts to maximize impact across its program areas.
Education - Preschool / Early Learning Early Childhood Development After School / Summer Educational Programs +15 more

Spartanburg County Foundation: Continuous Improvement Grant

Spartanburg County Foundation
Private
Spartanburg County, South Carolina
Up to US $35,000
The Spartanburg County Foundation's Continuous Improvement Grant aims to enhance the lives of Spartanburg County residents by funding nonprofit organizations that focus on quality of life, educational achievement, and economic mobility. Grants of up to $35,000 are available to eligible 501(c)(3) organizations. The foundation prioritizes projects that demonstrate alignment with its mission, utilize data-driven strategies, and foster community engagement, ensuring diverse populations receive necessary support and resources.
Community Culture & Heritage Food Access & Hunger Entrepreneurship +16 more

Spartanburg County Foundation: Nonprofit Effectiveness Grant

Spartanburg County Foundation
Private
Spartanburg County, South Carolina
Up to US $10,000
The Spartanburg County Foundation offers Nonprofit Effectiveness Grants of up to $10,000 to enhance the internal capacity of community-based organizations in Spartanburg County. These grants aim to strengthen governance, financial management, and overall organizational effectiveness. Eligible organizations must be recognized 501(c)(3) nonprofits serving Spartanburg residents, demonstrating alignment with the Foundation's mission and measurable impact. The Foundation seeks to promote philanthropy and community engagement, ensuring that funds are utilized to benefit local residents directly.
Community Culture & Heritage Food Access & Hunger Entrepreneurship +16 more

Hoblitzelle Foundation Grant

Hoblitzelle Foundation
Private
Texas
Unspecified amount
The Hoblitzelle Foundation Grant, established in 1942, supports nonprofit organizations in Texas, particularly in the Dallas area, with funding for capital projects such as construction and technology. The foundation prioritizes initiatives in arts, education, medical, and social services, investing over $252 million in various sectors. Eligible applicants must have a 501(c)(3) classification, and grants are not awarded for religious purposes or to individuals. This grant is a valuable resource for enhancing community impact.
Environment Disability Care & Services Health & Medicine +22 more

NC: Environmental Quality Incentives Program (EQIP) Grant

USDA: Natural Resources Conservation Service of North Carolina
Federal Government
North Carolina
Unspecified amount
The NC Environmental Quality Incentives Program (EQIP) Grant, offered by the USDA's Natural Resources Conservation Service, provides financial and technical assistance to farmers and landowners for implementing conservation practices. Eligible participants can receive support for projects addressing natural resource concerns on their lands, with contracts lasting up to ten years. This program also prioritizes specific categories, including socially disadvantaged and beginning farmers, ensuring equitable access to conservation funding.
Environmental Conservation Agriculture Forestry +8 more

NV: Environmental Quality Incentives Program (EQIP) Grant Program

USDA: Natural Resources Conservation Service of Nevada
Federal Government
Nevada
Unspecified amount
The Environmental Quality Incentives Program (EQIP) is a key initiative by the USDA's NRCS aimed at assisting farmers, ranchers, and forest landowners in integrating conservation practices into their working lands. With year-round applications, EQIP offers technical and financial assistance to address critical natural resource concerns, including improved water and air quality, soil health, and wildlife habitat enhancement. This program helps producers adopt sustainable practices that not only benefit the environment but also their agricultural operations.
Environmental Conservation Agriculture Forestry +8 more

Mano Amiga Program

Empresas Fonalledas
Private
Puerto Rico
Unspecified amount
The Mano Amiga Program, initiated by the Plaza Las Américas Foundation and the Plaza Del Caribe Foundation, aims to enhance social conditions in Puerto Rico. This program supports non-profits in key areas such as education, arts, health, and women's empowerment. The upcoming edition in August 2025 will focus on non-profits providing educational support, artistic training, health interventions for chronic diseases, and programs aimed at empowering women survivors of violence, fostering community resilience and growth.
Women's Rights & Equality Music Visual Arts +15 more

Opportunity Fund Grants

Opportunity Foundation
Private
Allegheny County, Pennsylvania, Armstrong County, Pennsylvania +4 more
US $7,500 - US $20,000
The Opportunity Fund Grants support small to midsize arts organizations and initiatives promoting social and economic justice, primarily benefiting the Greater Pittsburgh community. Funding areas include performing and visual arts, with a focus on projects led by Black and LGBTQ+ individuals. Grants are available for organizations with 501(c)(3) status or governmental entities. The fund emphasizes flexibility in its focus to adapt to community needs, ensuring diverse projects receive support.
Performing Arts Textile & Fiber Arts Dance +13 more

NAFC Healthcare Services Expansion Fund

National Association of Free and Charitable Clinics Inc
Private
United States
US $30,000 - US $50,000

NAFC Open Grant/Product Donation Applications

The National Association of Free and Charitable Clinics (NAFC) is the only nonprofit 501c(3) organization whose mission is solely focused on the issues and needs of the medically underserved throughout the nation and the more than 1,400 Free and Charitable Clinics that serve them. The NAFC has earned the Platinum Seal of Transparency from GuideStar and a 4-Star rating from Charity Navigator. Founded in 2001 and headquartered near Washington, D.C., the NAFC is working to ensure that the medically underserved have access to affordable quality healthcare and strives to be a national voice promoting quality healthcare for all. For more information about the NAFC, including how to become a member, please visit https://www.nafcclinics.org.

NAFC Healthcare Services Expansion Fund

The NAFC Healthcare Services Expansion Fund supports the launch or expansion of clinical programs and new service areas that increase access to care for underserved patients. This funding is designed to help NAFC members introduce new services or grow existing programs that address unmet community health needs and improve access to comprehensive, patient-centered care.

Health Facilities & Clinics Health Disparities & Social Determinants of Health Obstetrics & Neonatal Care +11 more

Kempner Fund: Micro-Grants

Harris & Eliza Kempner Fund
Private
Galveston County, Texas
Up to US $5,000
The Kempner Fund's Micro-Grants Program aims to empower new and smaller non-profit organizations in Galveston by providing seed funding of up to $5,000. This program is designed for organizations that are five years old or younger or have annual budgets below $500,000. It focuses on community-based solutions and innovative ideas to create a meaningful impact in the local area, ensuring that funding primarily supports the Galveston community.
Youth Services Children’s Mental Health Youth Development & Leadership +16 more

Kempner Fund: Navigation Fund

Harris & Eliza Kempner Fund
Private
Galveston County, Texas
Up to US $7,500
The Kempner Fund's Navigation Fund provides essential support to nonprofit organizations focused on strategic growth in Galveston, Texas. Eligible applicants, which must be current partners of the Kempner Fund, can apply for up to $7,500 to enhance their organizational resilience, governance, equity, and data measurement capabilities. The fund prioritizes proposals that demonstrate clear alignment with the Kempner Fund's mission and values, ensuring long-term community impact.
Sustainability Art & Culture Humanities & Social Science +17 more

SCF Community Grants

Shenandoah Community Foundation
Private
Shenandoah County, Virginia
US $250 - US $10,000
The SCF Community Grants support initiatives that enhance the quality of life in Shenandoah County, Virginia. Focusing on arts, civic affairs, environment, education, health, and social welfare, the Shenandoah Community Foundation welcomes proposals from 501(c)(3) organizations. These grants aim to strengthen community engagement and address local needs, fostering collaboration and innovative solutions for diverse challenges faced by residents.
Art Education Historic Preservation Community Development & Revitalization +23 more

BCBSNM Grants

Blue Cross Blue Shield of New Mexico
Corporate
New Mexico
Unspecified amount
Blue Cross and Blue Shield of New Mexico is committed to enhancing community health through grants and sponsorships. They focus on key areas such as economic opportunity, nutrition, and health outcomes, ensuring alignment with their mission. Organizations eligible for funding must be based in New Mexico and meet specific criteria, while projects that promote discrimination or are unrelated to their mission are ineligible. This initiative highlights their dedication to fostering a healthier community.
Nutrition & Healthy Eating Wellness & Healthy Living Physical Fitness +11 more

BCBSNM Sponsorship Funding

Blue Cross Blue Shield of New Mexico
Corporate
New Mexico
Unspecified amount
Blue Cross and Blue Shield of New Mexico (BCBSNM) is committed to enhancing community health and wellness through sponsorships and grants. Our focus areas include economic stability, nutrition, and optimal health outcomes, targeting local nonprofits to address pressing community needs. We invite applications from New Mexico organizations that align with our mission, with a particular emphasis on initiatives that foster healthier living. Please review our funding priorities before applying for sponsorship or grant opportunities.
Wellness & Healthy Living Nutrition & Healthy Eating Physical Fitness +11 more

The Staten Island Foundation Grant

The Staten Island Foundation
Private
Richmond County, New York
Unspecified amount
The Staten Island Foundation Grant aims to enhance the educational, health, and community service sectors in Staten Island. This grant prioritizes projects that show measurable benefits for the community, particularly for the least advantaged. Applicants must align their proposals with one of the Foundation's target outcomes and demonstrate a commitment to diversity, equity, and sustainability. For detailed guidelines and eligibility criteria, visit the Foundation's website.
Education - K through 12 Early Childhood Development Education - Preschool / Early Learning +22 more

Connecticut Conservation Stewardship Program (CSP)

USDA: Natural Resource Conservation Service of Connecticut
State/Local Government
Connecticut
More than US $4,000
The Connecticut Conservation Stewardship Program (CSP) supports farmers and landowners in enhancing their existing conservation efforts while improving agricultural operations. The program offers technical and financial assistance for practices that promote environmental stewardship, such as improving soil health and wildlife habitats. Participants can receive annual payments and bundles of enhancements, all while committing to a five-year contract aimed at sustainable land management. CSP is designed for all producers, regardless of operation size or type of crops.
Environmental Conservation Land / Habitat Conservation Environmental Stewardship +7 more

Soil and Water Stewardship Scholarship

Community Foundation of Northern Illinois
Private
United States
Unspecified amount
The Soil and Water Stewardship Scholarship, sponsored by the Community Foundation of Northern Illinois, provides financial support to students pursuing careers in natural resources. Applicants must reside in specific Illinois counties and plan to enroll in a full-time program related to fields such as ecology, hydrology, and conservation. Academic performance is a key consideration in the selection process. For more details, contact the Winnebago County Soil & Water Conservation District.
Environmental Stewardship Natural Resources Hydrology +15 more

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.