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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,618 Results based on applied filters

American Society for Theatre Research ( ASTR) David Keller Travel Grants

American Society for Theatre Research
Association/Society
United States
Up to US $800
The American Society for Theatre Research (ASTR) David Keller Travel Grants support untenured scholars with terminal degrees in attending the annual ASTR conference. With up to three $800 honorariums and complimentary registration, the grants aim to foster active participation in the organization. Eligible recipients include independent scholars and adjunct faculty, with selection based on their interest and achievements in scholarship and service. This initiative enhances networking and professional development within the theatre research community.
Theater

Friends of Pioneer Scholarship

Community Foundation Alliance, Inc.
Private
Spencer County, Indiana
US $1,990
The Friends of Pioneer Scholarship, established by Pioneer sales representatives, supports high school graduates and seniors in the LPH Territory who have a parent in agriculture. Eligible applicants must have a minimum 2.5 GPA and demonstrate community involvement. This initiative, managed by the Community Foundation Alliance, aims to empower local students pursuing higher education through financial assistance and recognition of their achievements in academics and community service.
Education - Higher Education Academic Scholarship Programs

Harold and Thelma Hunter Scholarship

Community Foundation Alliance, Inc.
Private
Spencer County, Indiana
US $490
The Harold and Thelma Hunter Scholarship, administered by the Community Foundation Alliance, Inc., supports graduating seniors of Heritage Hills High School who demonstrate financial need and strong moral character. Established in memory of Harold Hunter, this annual scholarship aims to assist students pursuing post-secondary education with a minimum GPA of 2.8. Preference is given to applicants ranked in the 50th to 90th percentile of their class, encouraging community engagement and perseverance.
Education - Higher Education Academic Scholarship Programs

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) (358090)

US Dept. of Health & Human Services: National Institutes of Health (NIH)
Federal Government
American Samoa, Guam +4 more
Up to US $375,000
The HEAL Initiative: Pain Research Enhancement Program (PREP) aims to support R15-eligible Principal Investigators in conducting rigorous pain research. This initiative promotes interdisciplinary partnerships and enhances the research environment for health professional trainees. Key deadlines include October 28, 2025, and October 27, 2026, for standard applications, and November 24, 2025, and November 23, 2026, for AIDS-related applications. Letters of Intent are encouraged 30 days prior to the due date.
Chronic / Acute Pain Anesthesia and Pain Medicine

United Nations Association of Connecticut (For Greater Hartford) Scholarship Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $1,000 - US $1,500
The United Nations Association of Connecticut Scholarship Fund, established by the Hartford Foundation for Public Giving, supports students with financial need who are interested in international issues and foreign language studies. Since 1945, the program has awarded nearly $30 million to students pursuing higher education. This scholarship specifically targets those who have demonstrated academic excellence and participation in Model UN or similar programs, offering one award annually to eligible applicants from the Greater Hartford region.
Education - Higher Education Academic Scholarship Programs

Division of Boating and Waterways Local Assistance Statewide- Non-Motorized Boat Launching Facility Grant Program

California Department of Parks and Recreation
State/Local Government
California
Unspecified amount
The Division of Boating and Waterways offers a Local Assistance Grant Program for the development of non-motorized boat launching facilities in California. Eligible applicants must own or control the project area and commit to operating and maintaining the facility for 20 years. The program aims to enhance public access to waterways, supporting local governments and agencies in improving marina infrastructure. Interested parties should contact the Division to discuss project suitability and application processes.
Recreational Water Use & Boating

Gene and Christina Schwindel Scholarship

Community Foundation Alliance, Inc.
Private
Spencer County, Indiana
US $3,480
The Gene and Christina Schwindel Scholarship, managed by the Community Foundation Alliance, Inc., supports graduating seniors or graduates of Heritage Hills High School in their pursuit of post-secondary education. This annual scholarship honors the contributions of Gene and Christina Schwindel and is part of a broader Community Scholarship Program that promotes educational opportunities for local students. The foundation's mission is to enhance community welfare through philanthropy and educational support.
Education - Higher Education Academic Scholarship Programs

ASTR Thomas Marshall Graduate Student Awards

American Society for Theatre Research
Association/Society
United States
Up to US $800
The ASTR Thomas Marshall Graduate Student Awards aim to support graduate students researching theatre or performance by assisting with the costs of attending the annual ASTR conference. This grant offers up to three honorariums of $800 each, along with complimentary conference registration. Eligibility is open to any graduate student in relevant fields, with selection based on the applicant’s interest and academic achievements.
Theater

2026 Pet Lover's Spay and Neuter Grant Program

CA Department of Food and Agriculture
State/Local Government
California
US $25,000 - US $50,000
The 2026 Pet Lover's Spay and Neuter Grant Program aims to reduce pet overpopulation in California by providing financial assistance for spay/neuter services. Funded through the Pet Lover’s License Plate Program and the Prevention of Animal Homelessness and Cruelty Tax Fund, this initiative expects to distribute up to $500,000 in grants ranging from $25,000 to $50,000 to eligible municipalities and non-profits, facilitating a healthier pet population.
Veterinary Science & Services Animal Welfare - Domestic Animals & Pets

Citizens Grants: Financial Empowerment

Citizens Charitable Foundation
Private
Albany County, New York, Allegany County, New York +66 more
Unspecified amount
The Citizens Grants: Financial Empowerment program supports nonprofits focused on creating measurable impacts in financial education for low to moderate income individuals and small businesses. This grant emphasizes partnerships with established 501(c)(3) organizations and encourages collaborative efforts that demonstrate alignment with funding priorities. By investing in financial literacy, Citizens aims to enhance fiscal health in underserved communities across select geographic areas.
Financial Literacy

Lamond GenNext Award

Namm Foundation
Private
Orange County, California
US $750
The Lamond GenNext Award, provided by the NAMM Foundation, supports students enrolled in college or technical programs related to music and entertainment technology. Awardees receive a $750 stipend and a badge for The NAMM Show, facilitating valuable networking and professional development opportunities. Eligible applicants must be sophomores or higher with a minimum GPA of 3.0, and the application cycle opens on April 21, closing on September 8.
Music

International Travel Grants

Society For Music Theory Inc
Private
Hennepin County, Minnesota
Up to US $650
The Society for Music Theory offers International Travel Grants to support theorists outside the US and Canada in attending the SMT Annual Meeting. Grants, typically ranging from $650, aim to alleviate travel costs and include complimentary registration. Open to all stages of scholars, including graduate students, the program prioritizes new applicants and junior scholars, emphasizing diversity and inclusivity in the field of music theory.
Music

Engagement Award: Dissemination Initiative

Patient Centered Outcomes Research Institute
Private
United States
Up to US $300,000
The Engagement Award: Dissemination Initiative, part of the Eugene Washington PCORI program, focuses on promoting active involvement of patients, families, and caregivers in health research. It supports organizations in effectively communicating PCORI-funded research findings to their audiences, enhancing understanding and application in healthcare decisions. Projects must demonstrate stakeholder engagement and a solid evaluation plan. This initiative aims to bridge the gap between research and community application, ensuring impactful dissemination of critical health information.
Patient Care & Services

Sailors' Snug Harbor of Boston: Special Three-Year Funding Initiative

Sailors Snug Harbor of Boston
Private
Barnstable County, Massachusetts, Bristol County, Massachusetts +6 more
Unspecified amount
Sailors' Snug Harbor of Boston has launched a Special Three-Year Funding Initiative aimed at enhancing social services for fishermen, their families, and low-income elders in Massachusetts' coastal communities. Grants up to $50,000 per year will be awarded to 501(c)(3) organizations to support innovative program approaches. The initiative prioritizes programs addressing the direct impacts of changes in the fishing industry and aims to prevent homelessness, ensuring vulnerable populations receive the necessary support.
Recreational Water Use & Boating

31Heroes: Emergency Grants

31Heroes
Association/Society
United States
Up to US $750

31Heroes

On August 6, 2011, a tragedy shook the military community and Americans everywhere. In a single instance, America lost 30 military service members, many of whom were members of the Navy SEAL community—and one military K9– when a CH-47 Chinook helicopter, call sign Extortion 17, was downed in Afghanistan.

Established to honor the 31 Americans killed in action on August 6, 2011, 31Heroes serves to impact the lives of our nation’s heroes and their families, while remembering the fallen, through athletic endeavors and competitive fundraising events.

Our Mission: The mission of 31Heroes is to raise money and awareness through social and athletic events to support the families of Extortion 17 and honor their legacy by funding treatment for Veterans suffering from mental health issues.

Our Focus

Our goal is to create opportunities for the families of Extortion 17 to create healthier lifestyles and to provide financial relief in times of need. We consider it our responsibility to make a positive impact in the lives of each family. Whether through grants we provide, or through partnering with other non-profit organizations that offer programs or services that we do not, we are devoted to the families and creating a legacy the men of Extortion 17 would be proud of.

Guidelines

  • Individual limits will not exceed $3750 annually
  • Family Grants range from $750 to the maximum range of $1500
  • Family members must submit an online application for consideration
  • Applications may be submitted at any time during this funding cycle
  • Priority and funding will be based on the Primary Next of Kin list

Emergency Grants 

Emergency Grants are aimed at assisting with unforeseen events which cause financial hardship on the family. Limit for this grant is $750.

Basic Human Needs Military & Veterans Services

Many Voices Travel Grants

Society For Music Theory Inc
Private
Hennepin County, Minnesota
Up to US $400
The Many Voices Travel Grant, offered by the Society for Music Theory, supports diverse participation in music theory scholarship. Designed for scholars, especially students, the grant aims to reduce barriers to attending the Annual Meeting, ensuring a wider range of voices and perspectives are represented. Up to 10 grants of $400 each, along with complimentary conference registration, are available to facilitate engagement with the discipline and promote inclusivity.
Music

Tim and Gerri Sullivan Scholarship Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $3,000
The Tim and Gerri Sullivan Scholarship Fund, administered by the Hartford Foundation for Public Giving, provides financial support to graduating high school seniors from Hartford attending public schools in Connecticut. This scholarship aims to assist students entering 2-year, 4-year, or vocational colleges on a full-time basis, demonstrating academic achievement and financial need. With a history of over $30 million awarded since 1945, this fund continues to empower local students towards higher education.
Education - Higher Education Academic Scholarship Programs

Dale and Marilyn Hasler Memorial Scholarship

Community Foundation Alliance, Inc.
Private
Spencer County, Indiana
US $1,170
The Dale and Marilyn Hasler Memorial Scholarship, established by family and friends, supports graduating seniors from Heritage Hills and Southridge High Schools. Eligible applicants must maintain a minimum 3.0 GPA on a 4.0 scale and seek a four-year engineering degree. The scholarship emphasizes financial need and community involvement, promoting educational advancement for local students. This initiative is part of the Community Foundation Alliance's broader mission to foster philanthropy and improve community wellbeing in southwestern Indiana.
Education - Higher Education Academic Scholarship Programs

SMT Student Presentation Award

Society For Music Theory Inc
Private
Duval County, Florida
US $250
The SMT Student Presentation Award, granted by the Society for Music Theory, recognizes outstanding scholarly presentations by graduate or undergraduate music students at their Annual Meeting. Eligibility is open to any student with an accepted paper or poster, with no additional nomination needed. Joint presentations are permitted, provided all presenters are students. This initiative supports inclusivity and diversity in music theory, fostering a vibrant academic community.
Music

Fertility Grants (VIVA Program)

Bob Woodruff Foundation
Private
American Samoa, Guam +4 more
Unspecified amount
The Fertility Grants (VIVA Program) by the Bob Woodruff Foundation offer vital financial support to wounded veterans facing infertility challenges due to their service-related conditions. Since its inception, the program has assisted over 100 veteran families in starting their own, highlighting a commitment to ensuring veterans have access to necessary fertility treatments. This initiative addresses the unique needs of veterans, recognizing that they experience infertility at nearly double the rate of the general population.
Military & Veterans Services Reproductive Health

Subventions for Events at the Annual Meeting

Society For Music Theory Inc
Private
Duval County, Florida
Unspecified amount
The Society for Music Theory (SMT) offers Subventions for Events at its Annual Meeting, aimed at enhancing music theory engagement. These grants support activities proposed by standing committees, interest groups, or individual members, focusing on costs for guest speakers, performers, and related expenses. SMT encourages diverse and inclusive participation in music theory, making this funding essential for fostering a rich academic environment. Applications are welcomed from chairs and members organizing events at the Annual Meeting.
Music

Cornelius R. Collignon Family Scholarship

Community Foundation Alliance, Inc.
Private
Spencer County, Indiana
US $2,170
The Cornelius R. Collignon Family Scholarship, managed by the Community Foundation Alliance, supports graduating seniors or graduates from Spencer County high schools pursuing a four-year degree in agriculture, forestry, or aviation. Established in memory of Cornelius R. Collignon, this scholarship honors his dedication to protecting natural resources. Eligible applicants must demonstrate leadership, patriotism, and financial need, with preference given to students entering their sophomore, junior, or senior year in college.
Education - Higher Education Academic Scholarship Programs

Brauns Family Scholarship

Community Foundation Alliance, Inc.
Private
Spencer County, Indiana
US $1,070
The Brauns Family Scholarship, established by Thomas and Vicki Brauns, supports graduating seniors from South Spencer High School who have attended Luce Elementary School for at least two years. The scholarship aims to assist students as they pursue post-secondary education at accredited institutions, contributing to their academic and future success. This initiative reflects the commitment of the Community Foundation Alliance to empower local students and enhance educational opportunities within the community.
Education - Higher Education Academic Scholarship Programs

The Walter S. Kapala Scholarship Trust

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $1,500
The Walter S. Kapala Scholarship Trust, established by the Hartford Foundation for Public Giving, offers financial support to high-achieving students from public high schools in Hartford or West Hartford. Since 1945, the foundation has awarded nearly $30 million in scholarships, assisting local students in pursuing higher education. This scholarship aims to help 1 to 2 deserving students each year who require financial assistance to achieve their academic goals.
Education - Higher Education Academic Scholarship Programs

Citizens Philanthropic Foundation Grant: Financial Empowerment

Citizens Philanthropic Foundation
Private
Bronx County, New York, Kings County, New York +4 more
Unspecified amount
The Citizens Philanthropic Foundation Grant for Financial Empowerment supports nonprofit organizations focused on providing financial education to low- and moderate-income individuals. The foundation prioritizes projects that demonstrate measurable impact, particularly those serving diverse populations in NJ and Metro New York. Eligible applicants must be IRS-qualified 501(c)(3) organizations and align their proposals with the foundation's goals of fostering financial literacy and collaboration with Citizens colleagues.
Financial Literacy

TMEA Research Grant Proposals

Texas Music Educators Association
Association/Society
Texas
Up to US $1,200
The Texas Music Educators Association (TMEA) offers an annual research grant of up to $1,200 aimed at enhancing music education. With nearly 20,000 members, TMEA focuses on diverse topics, including music teacher retention and social emotional learning. This grant supports research that promotes excellence in music education, welcoming proposals from active TMEA members in Texas. Through this initiative, TMEA aims to foster innovation and improve representation within music classes.
Music Education

PCORI Engagement Award: Capacity Building

Patient Centered Outcomes Research Institute
Private
United States
Up to US $300,000
The PCORI Engagement Award: Capacity Building aims to enhance the capacity of patients and stakeholders in patient-centered comparative clinical effectiveness research (CER). Projects can last up to two years with funding up to $300,000. Successful proposals will demonstrate understanding of CER, community engagement, and commitment from stakeholders. The initiative encourages the use of existing tools and resources to foster patient involvement in research processes, aligning with national health priorities and addressing pressing healthcare issues.
Patient Care & Services

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.