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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

33,000+

Available grants

$9.00B

Total funding

$6K

Median grant

33,000+ grants
$9.00B total
$6K median

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32,618 Results based on applied filters

Welcome Home Scholarship

Ann Arbor Area Community Foundation
Private
Washtenaw County, Michigan
Unspecified amount
The Welcome Home Scholarship, offered by the Ann Arbor Area Community Foundation, supports honorably discharged veterans returning from active duty in Operation Enduring Freedom or Operation Iraqi Freedom. This scholarship is part of a broader initiative that awarded over $650,000 in 2025 to help local youth pursue post-secondary education. It aims to ease the transition back to civilian life for veterans, ensuring they have the necessary resources to succeed in their educational endeavors.
Education - Higher Education Academic Scholarship Programs

Walter & Florence E. Aupperle Scholarship

Ann Arbor Area Community Foundation
Private
Washtenaw County, Michigan
Unspecified amount
The Walter & Florence E. Aupperle Scholarship, offered by the Ann Arbor Area Community Foundation, supports undergraduate students pursuing a major or minor in German Studies at Eastern Michigan University or the University of Michigan. Applicants must be enrolled full-time, maintain a minimum GPA of 3.0, and demonstrate financial need. This scholarship is part of a broader initiative that awarded over $650,000 to local students in 2025.
Education - Higher Education Academic Scholarship Programs

Pendleton and Elisabeth Carey Miller Charitable Foundation Grant

Pendleton and Elisabeth Carey Miller Charitable Foundation
Private
Oregon, Washington
Unspecified amount
The Pendleton and Elisabeth Carey Miller Charitable Foundation Grant supports civic and cultural institutions in the Pacific Northwest, with a focus on gardens, horticulture, and the region's history. Established in 1994, the foundation has distributed over $12 million to various organizations. Grants are available to 501(c)(3) organizations, including those named in Mrs. Miller's will or that support the study of Northwest history through literature. The foundation aims to continue the Millers' philanthropic legacy.
Historical Records & Archives History Horticulture & Gardening

Medical Assistance Grants

Vitalyst Health Foundation
Private
Maricopa County, Arizona
Up to US $375,000
The Medical Assistance Grants program, administered by the Vitalyst Health Foundation, aims to enhance healthcare access and quality for low-income and underserved populations in Maricopa County. The program supports nonprofit organizations that provide essential services in vision, hearing, heart and lung health, and substance use treatment. By leveraging existing resources, these grants facilitate improved community health outcomes and equity, addressing significant health disparities among vulnerable groups.
Vision Impairment Care & Services

Town and County Club Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
Up to US $5,000
The Town and County Club Fund, established by members of the Town and County Club in Hartford, aims to support adult women pursuing higher education. This initiative is part of the Hartford Foundation for Public Giving's Scholarship Program, which has granted nearly $30 million since 1945. Eligible applicants must be female, 25 years or older, residents of the Hartford area, and enrolled in specific Connecticut colleges with a minimum GPA of 2.5.
Education - Higher Education Academic Scholarship Programs

Villano-ebbo Scholarship Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $1,000 - US $2,000
The Villano-ebbo Scholarship Fund, managed by the Hartford Foundation for Public Giving, supports local students from the Greater Hartford region pursuing higher education in technology or entrepreneurship. Established by entrepreneur Vin Villano, this fund is dedicated to aiding one graduating high school senior with a strong academic record and financial need. The Hartford Foundation has a rich history of providing scholarships, contributing nearly $30 million since 1945 to foster educational opportunities for students.
Education - Higher Education Academic Scholarship Programs

NCR-SARE: Partnership Grant Program

North Central Region SARE
Federal Government
Illinois, Indiana +10 more
Up to US $50,000
The NCR-SARE Partnership Grant Program aims to enhance sustainable agriculture by fostering collaboration between agricultural professionals and groups of farmers. By facilitating innovative research and educational activities, this program supports projects that test new cropping strategies, develop marketing approaches, and enhance food security. Focused on the North Central Region, it encourages partnerships that drive on-farm research, ultimately improving economic viability and environmental stewardship for communities across 12 states.
Sustainable Agriculture & Agroecology

College Well-Being-Award

American College Health Foundation
Corporate
United States
Up to US $3,500
The College Well-Being Funding Opportunity aims to enhance the health of college students through innovative programs and research. Offered by the American College Health Foundation, it provides up to two awards of $3,500 to eligible institutions for improving campus infrastructure that promotes student well-being. This initiative encourages creativity and collaboration among campus health professionals to develop effective, measurable outcomes in student wellness. By fostering a culture of well-being, the foundation seeks to address the evolving needs of contemporary students.
Education - Higher Education Wellness & Healthy Living

NYSCA/NYFA Artist as Entrepreneur, Presented by Saratoga Arts

New York Foundation for the Arts
Private
Saratoga County, New York
Unspecified amount

About NYFA

We are a 501(c)(3) nonprofit service organization that offers in-person and virtual arts programs, services, and opportunities, tailored to the needs of our creative community.

Our Mission

Established in 1971, the mission of the New York Foundation for the Arts (NYFA) is to empower artists in all disciplines, as well as cultural workers, to achieve success on their own terms by providing critical support, resources, and opportunities. NYFA envisions a world where artists thrive in the practice and expression of their creative work, a world that celebrates and supports them. We serve approximately 1M constituents in person and online, annually, through four flagship programs: Learning, Awards & Grants, Fiscal Sponsorship, and Online Resources.

Artist as Entrepreneur Program

An intensive professional development program for artists of all disciplines, ranging from 1 to 3.5 days.

The NYSCA/NYFA Artist as Entrepreneur Program is an intensive professional development opportunity that serves artists and creatives of all disciplines (including visual, literary, and performing arts, among others). This 3.5 day program delves into the fundamental principles of sustainability in the arts, empowering artists with the tools to imagine and pursue success as they define it.

Whether you’re looking for a shift in thinking, strategies for your arts/creative business, or peer networks, this program provides dynamic planning tools for building a blueprint for your creative practice or arts project.

This program is made possible through New York State Council on the Arts, State & Local Partnerships with the support of the Governor’s Office and the New York State Legislature.

NYSCA/NYFA Artist as Entrepreneur Program, Presented by Saratoga Arts

Artists of all disciplines based in Saratoga, Fulton, and Montgomery Counties in New York State are encouraged to apply to participate in this FREE entrepreneurial program to be presented in Saratoga Springs, NY by Saratoga Arts from October 22-25, 2026.

Artist Training & Development Business Education

Friends of IU Scholarship

Community Foundation Alliance, Inc.
Private
Spencer County, Indiana
US $1,740
The Friends of IU Scholarship is an annual award established by Michael and Mary Schriefer and Larry and Charlene Hess, aimed at supporting graduating seniors from Heritage Hills High School who plan to attend Indiana University in Bloomington, Indiana. The scholarship focuses on financial need, leadership skills, and community involvement, with a preference for applicants majoring in education. This initiative is part of a broader Community Scholarship Program managed by the Spencer County Community Foundation.
Education - Higher Education Academic Scholarship Programs

Your Chance Scholarship Fund

Greater Hartford Gives Foundation
Private
Hartford County, Connecticut
US $1,000 - US $2,000
The Your Chance Scholarship Fund, established by the Hartford Foundation for Public Giving, supports students from the Greater Hartford area, particularly those in Bloomfield. This fund prioritizes high school graduates who have faced interruptions in their college education due to family or financial challenges. With 1-2 awards available, this scholarship aims to assist individuals in pursuing their educational goals at accredited colleges or vocational schools.
Education - Higher Education Academic Scholarship Programs

Elisa and Brian Peters Memorial Scholarship

Community Foundation Alliance, Inc.
Private
Spencer County, Indiana
US $1,000
The Elisa and Brian Peters Memorial Scholarship, established by the Peters Family, aims to support graduating seniors from Heritage Hills High School pursuing post-secondary education. This annual scholarship honors Elisa Peters, a passionate advocate for education and medical sciences. Preference is given to students entering medical science, STEM fields, or vocational trades. Managed by the Community Foundation Alliance, it exemplifies the commitment to enhancing local educational opportunities and fostering community development.
Education - Higher Education Academic Scholarship Programs

LibertyGives Foundation Grants

LibertyGives Foundation
Corporate
Colorado
Unspecified amount
The LibertyGives Foundation, established in 2007, focuses on enhancing charitable giving in Colorado, particularly for underprivileged and at-risk youth. With over $7 million contributed to various organizations, it emphasizes active employee involvement through sponsorship, volunteer work, and a matching program for donations. Eligible charities must be 501(c)(3) organizations based in Colorado and sponsored by a Liberty Media employee, ensuring a strong community connection and support for impactful services.
Youth Services Child Welfare Services

NYSCA/NYFA Artist as Entrepreneur, Presented by The ARTS Council of the Southern Finger Lakes

New York Foundation for the Arts
Private
Steuben County, New York
Unspecified amount

About NYFA

We are a 501(c)(3) nonprofit service organization that offers in-person and virtual arts programs, services, and opportunities, tailored to the needs of our creative community.

Our Mission

Established in 1971, the mission of the New York Foundation for the Arts (NYFA) is to empower artists in all disciplines, as well as cultural workers, to achieve success on their own terms by providing critical support, resources, and opportunities. NYFA envisions a world where artists thrive in the practice and expression of their creative work, a world that celebrates and supports them. We serve approximately 1M constituents in person and online, annually, through four flagship programs: Learning, Awards & Grants, Fiscal Sponsorship, and Online Resources.

Artist as Entrepreneur Program

An intensive professional development program for artists of all disciplines, ranging from 1 to 3.5 days.

The NYSCA/NYFA Artist as Entrepreneur Program is an intensive professional development opportunity that serves artists and creatives of all disciplines (including visual, literary, and performing arts, among others). This 3.5 day program delves into the fundamental principles of sustainability in the arts, empowering artists with the tools to imagine and pursue success as they define it.

Whether you’re looking for a shift in thinking, strategies for your arts/creative business, or peer networks, this program provides dynamic planning tools for building a blueprint for your creative practice or arts project.

This program is made possible through New York State Council on the Arts, State & Local Partnerships with the support of the Governor’s Office and the New York State Legislature.

NYSCA/NYFA Artist as Entrepreneur Program, Presented by The ARTS Council of the Southern Finger Lakes

Artists of all disciplines based in Cattaraugus, Chemung, Schuyler, Steuben, and Tioga Counties in New York State are encouraged to apply to participate in this FREE entrepreneurial program to be presented in Corning, NY by Arts Council of the Southern Finger Lakes from November 12-15, 2026.

Business Education Artist Training & Development

Omnibus Eviction and Homelessness Prevention RFP

State of New Jersey Department of Community Affairs
State/Local Government
New Jersey
Unspecified amount
The Omnibus Eviction and Homelessness Prevention RFP aims to provide essential support services, including legal assistance and case management, to low-income tenants at risk of eviction in New Jersey. By consolidating funding streams, this program addresses the critical issue of homelessness, which affects over 58% of admissions annually in the state. With an estimated $7 million in funding, the initiative seeks to prevent displacement and ensure access to necessary resources for vulnerable households.
Homelessness Services

Division of Boating and Waterways Local Assistance Statewide Sign Grant Program FY26

California Department of Parks and Recreation
State/Local Government
California
US $1,000 - US $6,000,000
The Division of Boating and Waterways Local Assistance Statewide Sign Grant Program FY26 offers funding for the installation and replacement of signs for previously funded projects. This initiative aims to ensure that signs are up-to-date, safe, and compliant with federal requirements. Grants support the improvement of public access to California's waterways, enhancing safety and user experience for the boating community. Applications are accepted until February 2, 2026, encouraging local agencies to participate in this vital program.
Recreational Water Use & Boating

Henry Jackson Crook Memorial Scholarship Fund

Communities Foundation of Texas
Private
Texas
Up to US $5,000
The Henry Jackson Crook Memorial Scholarship Fund, managed by Communities Foundation of Texas, provides financial support up to $5,000 annually for students attending the Episcopal School of Dallas. This scholarship aims to assist incoming freshmen through seniors who maintain a minimum 3.00 GPA and are citizens or legal residents. Established in 1953, the foundation is committed to fostering educational access and community growth.
Education - Higher Education Academic Scholarship Programs

Harris-Lee Ranch Scholarship

Communities Foundation of Texas
Private
Texas
US $5,000
The Harris-Lee Ranch Scholarship, provided by Communities Foundation of Texas, offers a one-year $5,000 award to a graduating senior from Throckmorton High School in Texas. This scholarship supports students pursuing a degree at an accredited college, university, or trade school. Selection is based on academic achievement, community involvement, leadership potential, and financial need, aiming to empower students to achieve their educational goals and contribute positively to their communities.
Education - Higher Education Academic Scholarship Programs

Clinical Research - Mentored Research Studies

American Speech Language Hearing Foundation
Private
Canada, United States
US $50,000
The Clinical Research - Mentored Research Studies grant supports new investigators, particularly post-docs, who collaborate with mentors to advance treatment efficacy in communication disorders. This funding encourages innovative research that directly impacts service delivery in audiology and speech-language pathology. Proposals must demonstrate a clear plan for mentorship and potential for future funding. Priority is given to studies with matching funds from universities or other sources, ensuring comprehensive support for impactful research.
Communication Disorders

Generation of Environmental Leaders Program

Commission for Environmental Cooperation
Association/Society
North America
C $15,000
The Generation of Environmental Leaders Program (GELP) invites youth aged 18-35 from Canada, Mexico, and the United States to propose innovative solutions to environmental challenges. This initiative not only empowers young leaders through mentorship and networking but also provides seed funding to support impactful projects. By encouraging collaboration and sustainable practices, GELP aims to foster long-term benefits for communities and the environment, ultimately preserving shared natural resources.
Environmental Conservation

MD Agricultural Conservation Easement Program (ACEP): Wetland Reserve Easements (WRE)

USDA: Natural Resources Conservation Service of Maryland
State/Local Government
Maryland
Unspecified amount
The MD Agricultural Conservation Easement Program (ACEP) offers Wetland Reserve Easements (WRE) to protect, restore, and enhance wetlands degraded by agricultural practices. NRCS prioritizes applications that support habitat for migratory birds and wildlife. Eligible landowners receive technical and financial assistance for restoration, with options for permanent, 30-year, and term easements. This initiative enhances biodiversity, improves water quality, and supports various ecological benefits, making it essential for environmental conservation in Maryland.
Land / Habitat Conservation

ASTR Theater and Performance Art Studies Research Fellowships

American Society for Theatre Research
Association/Society
United States
Up to US $3,000
The ASTR Theater and Performance Art Studies Research Fellowships provide funding for scholars conducting significant research in theatre and performance studies. With awards up to $3000, these fellowships support academic projects, allowing recipients to cover various research expenses. Eligible applicants include anyone holding a terminal degree and a member of ASTR, with the selection based on project merit. However, applicants cannot seek a Targeted Research Area Grant for the same project in the same year.
Theater

NAMM Foundation-College Music Society Fellows Award

Namm Foundation
Private
Orange County, California
US $500
The NAMM Foundation-College Music Society Fellows Program offers a $500 cash award to college music faculty dedicated to enhancing curricula in music and related industries. This initiative fosters professional development through networking events, industry panels, and access to The NAMM Show. Selected fellows will also participate in the GenNext program, which engages over 2,500 music students and faculty for career exploration. This program emphasizes the importance of creating pathways for students to connect with the music industry.
Music

Maryland Forest Legacy Program

Maryland Department of Natural Resources
State/Local Government
Allegany County, Maryland, Anne Arundel County, Maryland +20 more
Unspecified amount
The Maryland Forest Legacy Program aims to protect vital forest areas from conversion to non-forest uses through conservation easements. This federal initiative collaborates with state efforts to identify and preserve environmentally significant forests, with funding support where the federal government covers up to 75% of costs. Eligible areas must be designated Forest Legacy Areas, ensuring that at least 75% of the land remains forested. This program not only benefits wildlife but also supports local economies and water quality.
Land / Habitat Conservation

MD Agricultural Management Assistance Program (AMA)

USDA: Natural Resources Conservation Service of Maryland
State/Local Government
Maryland
Up to US $50,000
The Maryland Agricultural Management Assistance Program (AMA) supports farmers in managing financial risks through conservation practices. Eligible producers can receive up to 75% of installation costs for practices that enhance water management and quality, and soil conservation. With a funding cap of $50,000 per fiscal year, the AMA also offers higher cost-share rates for historically underserved producers, ensuring equitable access to resources for sustainable agricultural development.
Farms & Farming

Tucker Lee Everyone Plays Fund

Emporia Community Foundation
Private
Chase County, Kansas, Coffey County, Kansas +3 more
Unspecified amount

About the Emporia Community Foundation

Our Mission

To connect caring people with causes that build stronger communities within the Emporia area which includes Chase, Coffey, Greenwood, Lyon, Morris, Osage and Wabaunsee counties.

Tucker Lee Everyone Plays Fund

Tucker Lee was a 2015 graduate of Emporia High School and continued his education at Emporia State University where he was a member of the Sig Tau Gamma fraternity. He majored in Accounting and Health Promotions. He was employed at Wright CPA until his death, June 9, 2021 from NUT Carcinoma, a rare, fast-growing cancer. Growing up Tucker played on many REC and traveling teams. In high school, he played football and wrestled all 4 years. He enjoyed playing and building lifelong friendships.

In memory of Tucker’s caring nature and wanting everyone to be able to participate in athletics, The Tucker Lee Everyone Plays Fund was created in his honor with the Emporia Community Foundation (ECF). This fund is intended to help alleviate some of the financial burden on Lyon County area families, by offering financial aid to help with the cost of equipment, fees, and gear. Students in the following school districts are able to apply: USD 243 Lebo-Waverly, USD 251 North Lyon County, USD 252 Southern Lyon County, USD 253 Emporia, and USD 284 Chase County.

Scholarships will be available as long as funds are available.

Youth Services Sports & Athletics

ASTR Teacher-Researchers Grant

American Society for Theatre Research
Association/Society
United States
Up to US $1,000
The ASTR Teacher-Researchers Grant supports faculty with heavy teaching loads and limited research resources in theatre studies. This grant fosters scholarly exchange by providing an honorarium of up to $1000, complimentary conference registration, and a one-year ASTR membership. Applications are evaluated based on project feasibility and significance, with additional consideration for those facing institutional research support challenges. This initiative aims to enhance diversity and facilitate meaningful contributions to the field.
Theater

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.34B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: November 2, 2026. Next update: December 6, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

1,000+ Grants on Instrumentl focused on Workforce Preparation & Job Readiness

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.7%
Q2
24.7%
Q3
23.5%
Q4
22.1%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $32,500.

$0 $0 Min.
$32,500 $32.5 K Median
$633,837 $633.8 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.7% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $32,500, while the average grant awarded is $633,837. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.