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Best Sioux Falls Grants for Nonprofits in South Dakota

Looking for grants for 501(c)(3) nonprofit organizations working in Sioux Falls, South Dakota? Find the perfect grant for your nonprofit on Instrumentl.

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Environmental Grantmaking Program at EFA

Educational Foundation of America
Private
United States
Unspecified amount
The Environmental Grantmaking Program at the Educational Foundation of America (EFA) aims to support projects that facilitate a transition to a net-zero electricity system. Focused on reducing greenhouse gas emissions, the program emphasizes initiatives that enhance access to affordable clean energy, accelerate regional transitions, and strengthen financial investment in electric utilities. Eligible applicants include 501(c)3 public charities, academic institutions, and government entities committed to sustainable energy solutions.
Environmental Justice & Advocacy Environmental Economics Renewable/Sustainable Energy

Ocean Engineering and Instrumentation Ph.D. Fellowship

Link Foundation
Private
Canada, United States
US $35,000
The Link Foundation offers the Ocean Engineering and Instrumentation Ph.D. Fellowship, providing six fellowships of $35,000 each for Ph.D. students. This fellowship aims to advance research in ocean engineering and instrumentation, enhance theoretical and practical knowledge, and promote research dissemination through lectures and publications. Eligible candidates must be enrolled in a Ph.D. program at a U.S. or Canadian university and demonstrate a well-defined thesis direction. This funding can significantly support their academic journey.
Oceanography

Michael Foundation Grant

The Michael Foundation Inc.
Private
North America
US $2,000 - US $10,000
The Michael Foundation Grant supports Waldorf Education in North America, focusing on training centers and individuals. Grants typically range from $2,000 to $6,000, with occasional larger amounts. Eligibility includes AWSNA/WECAN membership and a commitment to diversity, equity, and inclusion practices. The foundation prioritizes teacher training programs and requests from individuals who have completed their initial training year, aiming to assist those most in need.
Education

Harris & Frances Block Foundation Grant

Harris and Frances Block Foundation
Private
United States
Up to US $35,000
The Harris and Frances Block Foundation, established in 2001, supports small grassroots organizations focused on social and environmental justice. They prioritize equitable solutions and sustainable community development, funding initiatives related to environmental education, justice, and food security. Grants are available to non-profit, tax-exempt organizations in specific geographical areas including Vermont, North Carolina, Virginia, and New York City, excluding funding for lobbying, land acquisition, and scholarships.
Food Access & Hunger Environmental Justice & Advocacy Agricultural Education +2 more

Kalliopeia Foundation Grant

Kalliopeia Foundation
Private
United States
Unspecified amount
The Kalliopeia Foundation Grant focuses on supporting projects that foster cultural and ecological renewal through a deep reverence for the Earth. By prioritizing US-based organizations that demonstrate strong community relationships and intergenerational leadership, the foundation seeks to empower marginalized voices and traditional practices. With an emphasis on land care and Indigenous leadership, Kalliopeia aims to cultivate a resilient future where diverse ways of knowing and being thrive harmoniously with nature.
Science Communications Environment Ecology +7 more

McKnight Endowment Fund for Neuroscience: Neurobiology of Brain Disorders Award

The McKnight Foundation
Private
United States
Up to US $300,000
The McKnight Endowment Fund for Neuroscience offers the Neurobiology of Brain Disorders Award to support innovative research aimed at understanding and treating brain disorders. It provides up to four awards of $100,000 each year for three years, encouraging proposals that explore biological mechanisms and environmental contributions to neurological disorders. The program emphasizes inclusivity and collaboration among researchers to advance the field and improve therapeutic interventions for conditions such as Alzheimer's and Parkinson's disease.
Neuroscience Neurological Diseases & Disorders Mental Health & Psychiatric Diseases

Family Medicine Cares- USA Free Health Clinics Grants ( New Clinics)

American Academy of Family Physicians Foundation
Corporate
United States
Up to US $25,000
The Family Medicine Cares USA Free Health Clinics Grants support new and existing clinics in the U.S. that provide care to the uninsured. With applications accepted annually from March 15 to July 15, these grants assist clinics in purchasing essential medical equipment. The initiative aims to address the needs of over 50 million uninsured individuals, ensuring access to primary care and promoting volunteerism among AAFP members and medical students. Grants of up to $10,000 are available to eligible clinics.
Health Facilities & Clinics

ECMC Foundation: Grants & Investments

ECMC Foundation
Private
Puerto Rico, United States
Unspecified amount
The ECMC Foundation focuses on eliminating equity gaps in postsecondary education by 2040 through strategic grantmaking and investments. They support organizations aiming to remove barriers to completion, build institutional capacity, and transform the postsecondary ecosystem. Eligible entities include nonprofit organizations, government entities, and postsecondary institutions. However, funding is not available for personal scholarships, political activities, or projects outside the U.S. that do not align with the Foundation's mission of diversity and inclusion.
College Success / Persistence Career / College Preparation Education - Higher Education +1 more

De Colores Rapid Response Fund

Peace Development Fund
Private
United States
US $500 - US $1,000
The De Colores Rapid Response Fund, established by the Peace Development Fund, aims to provide swift financial support to grassroots organizing efforts in marginalized communities, particularly focusing on communities of color and low-income individuals. Inspired by the traditional Mexican song that symbolizes diversity and solidarity, this fund seeks to create impactful opportunities for strategic interventions in urgent social situations. Grants are available for projects under $5,000 that align with these goals.
Social Justice / Human Rights Disaster Relief / Humanitarian Aid

Paul L. Busch Award

Water Research Foundation
Private
United States
Up to US $100,000
The Paul L. Busch Award, provided by the Water Research Foundation, honors individuals for innovative research in water quality. This prestigious award supports promising researchers with a $100,000 grant to advance their work. The selection process is inclusive, with no restrictions based on race, gender, or nationality, and encourages applications from diverse candidates. Recipients are expected to collaborate with U.S.-based organizations, fostering practical applications of their research in the water environment.
Sanitation & Clean Drinking Water Water Resource Management Freshwater Conservation

Oklahoma City Community Foundation: Kirschner Trusts Grant

Oklahoma City Community Foundation
Private
United States
Up to US $40,000
The Oklahoma City Community Foundation administers the Kirschner Trusts, established to honor Phil and Roberta Kirschner's philanthropic legacy. These trusts focus on supporting young individuals with disabilities, Muskogee nonprofits, and Jewish causes. Since their transfer to the foundation in 2013, the trusts have continued to provide vital grants to organizations that align with the Kirschners’ values, ensuring their charitable impact persists in the community.
Youth Services Education Disability Care & Services +4 more

Infinite Hero Foundation Grant Program

Infinite Hero Foundation
Private
United States
Up to US $100,000
The Infinite Hero Foundation Grant Program supports military personnel and their families by funding innovative treatment programs for service-related injuries. Since 2012, it has awarded over $5.7 million to 51 organizations focused on physical rehabilitation, mental health, leadership development, family support, and suicide prevention. Grants up to $100,000 are available for programs that align with the foundation's mission, ensuring that funds directly support program costs and not administrative expenses.
Military & Veterans Services Post-Traumatic Stress Disorder

Wild Ones Seeds for Education Grant Program

Wild Ones
Private
United States
US $100 - US $500
The Wild Ones Seeds for Education Grant Program aims to engage youth in environmental stewardship by funding projects that promote the use of native plants. This initiative supports schools and community organizations in creating native plant gardens, fostering a deeper understanding of biodiversity and sustainable practices among students. By providing necessary resources, the program encourages hands-on learning experiences for preschool through high school students, aligning with Wild Ones' mission to enhance natural landscapes.
Horticulture & Gardening Greening & Beautification

MWDSC: Innovative Conservation Program Funding

The Metropolitan Water District of Southern California
State/Local Government
United States
Up to US $50,000
The Metropolitan Water District of Southern California's Innovative Conservation Program (ICP) has funded innovative water savings projects since 2001, with $250,000 available biannually. The program aims to evaluate and demonstrate the reliability of new water-saving technologies. Nearly 400 proposals have sought $36 million in funding. The ICP, supported by multiple agencies, encourages projects that can benefit Southern California's water efficiency, inviting proposals from outside its service area to enhance regional water management.
Water Resource Management

COPIC Medical Foundation Grants

Copic Medical Foundation
Private
United States
Unspecified amount
The COPIC Medical Foundation Grants aim to improve healthcare outcomes by funding programs that enhance patient safety and reduce medical errors. With over $10 million awarded since its inception in 1991, the foundation focuses on scalable solutions to address healthcare fragmentation. This final grant cycle emphasizes innovative approaches that can be replicated across the healthcare community. Organizations must be 501(c)(3) certified or have a fiduciary partner to qualify for funding.
Medical Education & Professional Training Health Information Technology Patient Safety +1 more

Conservation Service Corps Grants

Great Outdoors Colorado
Private
Colorado, Countries
Unspecified amount
The Conservation Service Corps Grants, funded by Great Outdoors Colorado, support outdoor recreation and natural resource projects by hiring youth and veterans through conservation service corps. Annually, $1.5 million is allocated for these initiatives, enabling crews to tackle various projects like trail maintenance, invasive species mitigation, and wildlife habitat improvement. This program not only enhances natural resources but also provides job training and leadership skills to over 1,700 young participants each year.
Habitat & Ecosystem Restoration

Community Innovation Grants

Bush Foundation
Private
Minnesota, North Dakota +1 more
Unspecified amount
The Community Innovation Grants, funded by the Bush Foundation, aim to support transformative ideas that enhance the lives of people in Minnesota and surrounding areas. These grants foster collaboration among organizations and leaders to develop and spread effective solutions to community challenges. By removing funding caps and focusing on the needs of communities, the program empowers individuals and organizations to create lasting change, ensuring that innovative ideas reach their full potential.
Community Services

Psychosocial Research - PSR Postdoctoral Fellowship

Craig H. Neilsen Foundation
Corporate
Canada, United States
Up to US $200,000
The Craig H. Neilsen Foundation's Psychosocial Research Postdoctoral Fellowship supports early-career researchers in spinal cord injury (SCI) psychosocial studies. It aims to enhance professional interest and training in this vital field, focusing on areas such as caregiving, employment, and technology access. The fellowship offers mentored training, covering salary and up to $35,000 for non-personnel costs over two years, ensuring comprehensive support for fellows to advance their careers.
Spinal Cord Injuries

Entergy’s Open Grants Program

Entergy Charitable Foundation
Corporate
United States
Unspecified amount
Entergy’s Open Grants Program aims to enhance community well-being through funding initiatives in arts, education, social services, and community improvement. The program prioritizes support for organizations that serve diverse populations, including children and low-income communities. Eligible entities must have 501(c)(3) status or equivalent nonprofit recognition. Applications should be submitted three months in advance, allowing ample time for review. Entergy focuses on projects that foster self-sufficiency and enrich local neighborhoods.
Youth Services Family Services Community Development & Revitalization +11 more

Rachael and Ben Vaughan Foundation Grants

Rachael and Ben Vaughan Foundation
Private
United States
Unspecified amount
The Rachael and Ben Vaughan Foundation offers grants ranging from $2,000 to $20,000 for projects focused on animal rights, education, environmental preservation, poverty reduction, and religious initiatives. The foundation prioritizes local Texas projects but accepts applications from outside the state. Grants are awarded only to tax-exempt organizations, and projects should be completed within twelve months. The foundation aims to support initiatives that benefit local communities without duplicating existing efforts.
Education Environmental Conservation Poverty Alleviation & Services +2 more

RMEF Grant Program- Land Conservation and Access

Rocky Mountain Elk Foundation (RMEF)
Private
Arizona, California +14 more
US $5,000 - US $50,000

The RMEF Grant Program lies at the core of advancing our mission.

RMEF established the program in 1986 to provide financial and logistical support to projects that align with our priorities and goals. Grant funds raised by RMEF members, volunteers and generous donors from across the country translate into significantly more conservation accomplishment when matched with partner funds. The RMEF Grant Program also aims to build recognition for RMEF’s work, grow engagement, and boost local fundraising efforts.

Governed by clear guidelines and criteria, the RMEF Grant Program seeks to foster meaningful collaborations and long-term impacts in the conservation of natural resources and outdoor traditions. Grant project partners include federal, state, local, and tribal wildlife and land management agencies, private landowners and local stakeholders, sportsmen and women, and conservation organizations, universities, foundations and the outdoor industry. Eligible projects primarily focus on habitat stewardship, land conservation and access, wildlife management, and hunting heritage.

We support organizations recognized by the Internal Revenue Service (IRS) as a 501(c)3 entity, federal, state, local, or tribal government entities, sportsmen’s organizations, or educational institutions. All applicants must have a Federal Employer Identification Number (EIN) issued by the IRS. RMEF does not offer grants to individuals.

Land Conservation and Access

RMEF conserves critical big game habitat and migration corridors, while expanding and improving public access, including through land acquisitions and voluntary conservation agreements. RMEF's

2026 priorities include:

  • Conserving migratory corridors and connecting landscapes through land conservation efforts
  • Creating new or improved public access through access easements and agreements and state-run access programs
Land / Habitat Conservation

BF Disaster Relief Grants

Banfield Foundation
Private
United States
Up to US $10,000
The Banfield Foundation's Disaster Relief Grants support nonprofit animal welfare organizations and government agencies affected by natural disasters. Since 2015, the foundation has provided resources to help pets in crisis, including medical supplies, food, and temporary shelter. Grants are also available for organizations assisting those impacted by disasters. Eligible applicants must have 501(c)(3) status and directly help animals and their owners in the U.S., ensuring that pets receive the care they need during emergencies.
Animal Welfare - Domestic Animals & Pets

PEDIGREE Foundation: Program Development Grants

PEDIGREE Foundation
Corporate
United States
US $10,000 - US $15,000
The PEDIGREE Foundation offers Program Development Grants aimed at enhancing dog adoption rates by supporting shelters and rescues across the U.S. Established in 2008, the foundation prioritizes initiatives such as transport, matching, and foster programs. Funding is available to 501(c)(3) designated organizations committed to improving the quality of care for dogs and ultimately increasing their chances of adoption, ensuring that every dog finds a loving home.
Animal Welfare - Domestic Animals & Pets

Petco Love Stories Grant Campaign

Petco Love
Corporate
United States
US $5,000 - US $100,000
The Petco Love Stories Grant Campaign celebrates the profound impact of pet adoption. Each year, Petco Love and BOBS® from Skechers® award grants to animal welfare organizations that facilitate these life-changing adoptions. Since 2013, over $8 million has been distributed to support these organizations. Pet parents are encouraged to share their unique love stories about their adopted pets, showcasing how their lives have been enriched. Compelling narratives and quality visuals will help submissions stand out.
Animal Welfare - Domestic Animals & Pets

Animal Welfare Organizations Grants

Petco Love
Corporate
United States
Unspecified amount
The Petco Foundation offers grants aimed at animal welfare organizations, focusing on enhancing adoption and medical care initiatives. With a commitment to lifesaving programs, they invest in organizations that demonstrate accountability and significant impact in their communities. Eligible applicants include non-profit organizations, municipal agencies, and SPCA/humane societies that provide sheltering services. The grant cycle allows for one proposal submission per year, ensuring support for those dedicated to improving the welfare of companion animals.
Animal Welfare - Domestic Animals & Pets

Access to Care Grant

Petco Love
Corporate
United States
Unspecified amount
The Petco Love Foundation, previously known as the Petco Foundation, has been dedicated to animal welfare since 1999. With a mission to enhance the lives of pets and their families, they provide significant funding to nonprofit organizations for lifesaving initiatives. The 'Access to Care' program supports spay/neuter clinics and low-cost veterinary services, ensuring that more pets receive essential care. Petco Love remains committed to fostering healthier communities and improving the well-being of pets across the nation.
Animal Welfare - Domestic Animals & Pets

Petfinder Disaster Response and Recovery Grants

Petfinder Foundation
Private
Canada, Mexico +1 more
Up to US $10,000
The Petfinder Foundation's Disaster Response and Recovery Grants provide crucial support to Petfinder members affected by natural disasters. These grants assist organizations in recovering from events like hurricanes, tornadoes, and floods, ensuring that adoptable pets receive necessary care. Eligible applicants must be active Petfinder members and demonstrate a need due to disasters occurring within the past 60 days. The initiative aims to enhance the resilience of shelters and rescue groups in challenging times.
Animal Welfare - Domestic Animals & Pets

Sioux Falls Grants for Nonprofits Highlights

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