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Best Large Grants for Nonprofit Organizations

Get large grants for nonprofits scaling impact through capital projects, innovation, strategic growth, or infrastructure.

32,000+

Available grants

$8.25B

Total funding

$6K

Median grant

32,000+ grants
$8.25B total
$6K median

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32,499 Results based on applied filters

Goodwin Family Memorial Trust Grant

The Goodwin Family Memorial Trust
Private
California
US $10,000 - US $35,000
The Goodwin Family Memorial Trust Grant supports the moral, physical, and intellectual development of needy males under 21 in California. Established by Mabel Frankie Goodwin, the trust focuses on education, health, and human services. Grants range from $10,000 to $35,000, with 35 grants awarded annually, totaling up to $600,000 in yearly giving. Organizations must be 501(c)(3) public charities and wait one year after four consecutive grants before reapplying.
Youth Services Children’s Health & Pediatrics Children’s Mental Health +5 more

City of Hillsboro Community Impact Grant

City of Hillsboro, Oregon
State/Local Government
Washington County, Oregon
Up to US $120,000
The City of Hillsboro Community Impact Grant provides up to $120,000 in funding for nonprofit organizations to address community concerns over three years. Organizations can submit one application per cycle and must be qualified 501(c)(3) nonprofits serving Hillsboro residents. Priority areas are identified collaboratively, focusing on unique projects that deliver measurable outcomes and financial stability, especially in housing stability initiatives.
Equitable & Affordable Housing Homeownership Supportive Housing & Shelters

LifeCare Health Care Fund Grants

The Northwest Minnesota Foundation
Private
Roseau County, Minnesota
Unspecified amount
The LifeCare Health Care Fund Grants, managed by the Northwest Minnesota Foundation, aim to support nonprofit organizations in Roseau County with financial assistance for health-related projects and services. These grants focus on initiatives like diabetes care, cancer support, and wellness programs, promoting better health outcomes in the community. Eligible nonprofit applicants can request funding from various specialized endowment funds to address pressing healthcare needs and enhance community well-being.
Diabetes Kidney Diseases Health Care Access & Delivery +2 more

Communities Caring for Canopy Grants

Vermont Department of Forests, Parks and Recreation
State/Local Government
Vermont
US $5,000 - US $10,000
The Communities Caring for Canopy grants offer vital seed funding for communities to establish and maintain urban forestry programs in Vermont. With a total of $40,000 available for projects like tree planting, maintenance, and public outreach, individual awards range from $5,000 to $10,000. This initiative encourages collaboration and innovation in managing local tree resources, ensuring community engagement and environmental sustainability.
Habitat & Ecosystem Restoration Forestry

Septic Environmental Program to Improve Cleanliness (SEPTIC) Grant

Nassau County, New York
State/Local Government
Nassau County, New York
Up to US $20,000
Nassau County has launched the Septic Environmental Program to Improve Cleanliness (SEPTIC) Grant, aimed at replacing outdated septic systems with innovative nitrogen-reducing technologies. Grants of up to $20,000 are available for eligible homeowners and small businesses, addressing nitrogen pollution—an urgent concern for Long Island's water quality. This initiative supports public health and environmental sustainability, significantly reducing nitrogen discharge while ensuring effective wastewater treatment.
Water Resource Management Waste Management

Coastal Fund (CF) Grant - Minor Funding

University of California, Santa Barbara
Private
Santa Barbara County, California
Up to US $1,000
The Coastal Fund (CF) Grant provides vital funding to support projects that preserve and enhance coastal ecosystems at the University of California, Santa Barbara. Aimed at fostering community engagement and environmental stewardship, the grant encourages proposals that align with the Coastal Fund's mission. Eligible applicants include UCSB-affiliated departments and registered nonprofits, with funding typically around $200,000 allocated quarterly. This initiative is essential for advancing ecological research and restoration efforts in the Santa Barbara region.
Environment Ecology Land / Habitat Conservation +6 more

Fiesta Sports Foundation Grant

Fiesta Sports Foundation
Private
Arizona
US $15,000 - US $50,000
The Fiesta Sports Foundation Grant aims to support Arizona nonprofit organizations that enhance community success through youth, sports, and education. With a new two-step application process for the 2025-26 cycle, interested organizations must submit an interest form highlighting project impact and budget. The foundation will review submissions based on alignment with its pillars and specific criteria, including project sustainability and community focus, before inviting selected nonprofits to apply formally in April 2025.
After School / Summer Educational Programs Tutoring & Mentoring Art Education +6 more

Multifamily Finance Super NOFA – Los Angeles

California Department of Housing and Community Development
State/Local Government
California
US $3,000,000 - US $15,000,000
The T2025 Multifamily Finance Super NOFA for Los Angeles allocates approximately $101 million to support multifamily housing and infrastructure projects in areas affected by wildfires in January 2025. The California Department of Housing and Community Development aims to expedite affordable housing solutions for disaster survivors through two application phases, emphasizing immediate construction and readiness. Eligible programs include Multifamily Housing, Supportive Housing, and Infrastructure Grant initiatives, all focused on enhancing housing stability and community recovery.
Military & Veterans Services Homelessness Services Real Estate & Housing +2 more

California Drought Funding Grants

California State Water Resources Control Board
State/Local Government
California
Unspecified amount
The California Drought Funding Grants, provided by the California State Water Resources Control Board, aim to support projects addressing urgent drinking water needs and long-term resilience due to drought. Eligible applicants include public agencies, tribal governments, community water systems, and non-profits serving disadvantaged communities. Funding covers both short-term solutions like emergency repairs and long-term improvements such as new wells and treatment systems, ensuring a sustainable water supply for affected regions.
Sanitation & Clean Drinking Water Natural Disaster Science Water Resource Management

Growing Healthy Kids Grant

The Sprouts Healthy Communities Foundation
Corporate
Alabama, Arizona +22 more
US $5,000 - US $10,000
The Growing Healthy Kids Grant, funded by The Sprouts Healthy Communities Foundation, aims to support community-based programs that enhance children's nutrition access and health education. With grant amounts ranging from $5,000 to $10,000, this initiative focuses on hands-on programs that promote healthy habits among children and their families. Eligible organizations must be 501(c)(3) nonprofits located in areas where Sprouts Farmers Market operates, helping to ensure that the funds directly benefit local communities.
Children’s Health & Pediatrics Family Services Children’s Mental Health +3 more

PHSA Community Fdn.- Community and Youth Grants

Petoskey-Harbor Springs Area Community Foundation
Private
Emmet County, Michigan
Approximately US $7,800
The PHSA Community Foundation offers Community and Youth Grants to enhance life in Emmet County. With two application cycles each year, the foundation has distributed over $300,000 per cycle, averaging $7,800 per grant. They welcome requests of all sizes and offer support from various funds. This initiative is designed to meet diverse local needs, ensuring that community projects receive the necessary funding to thrive.
Human & Social Services Youth Services Art & Culture +8 more

St. Mary's Bank Charitable Foundation 1908 Fund Grant

St. Marys Bank Charitable Foundation
Private
United States
US $500 - US $5,000
The St. Mary's Bank Charitable Foundation 1908 Funds Grants provide financial support to nonprofit organizations in New Hampshire, focusing on community development and services. Established to uphold St. Mary’s Bank's commitment to social responsibility, these grants, ranging from $500 to $5,000, aim to foster financial independence and address issues like homelessness, youth support, and civic engagement. The Foundation prioritizes projects that benefit local communities and promote long-term sustainability.
Financial Literacy Basic Human Needs Military & Veterans Services +5 more

Recycling Assistance Grant Program

West Virginia Department of Environmental Protection
State/Local Government
West Virginia
US $75,000 - US $150,000
The Recycling Assistance Grant Program, funded by a $1.00 fee on solid waste disposal in West Virginia, aims to support counties, municipalities, and other entities in establishing and enhancing recycling initiatives. Grants are available for feasibility studies, educational programs, and market procurement efforts. Public entities can receive up to $150,000, while private entities can secure a maximum of $75,000 to bolster their recycling programs and public awareness campaigns.
Waste Management Recycling

Delaware River Watershed Protection Fund: Catalyst Grants

Open Space Institute Land Trust Inc.
Private
Atlantic County, New Jersey, Berks County, Pennsylvania +36 more
US $10,000 - US $35,000
The Delaware River Watershed Protection Fund: Catalyst Grants, initiated in 2014 by the Open Space Institute, aims to enhance water resource management and land protection. These grants support organizations addressing climate change, environmental justice, and community resilience. Eligible applicants include not-for-profit organizations and Indigenous-led groups. Funded projects should integrate science into conservation plans, focusing on water quality and stewardship. The initiative collaborates with the William Penn Foundation to ensure sustainable water practices across the Delaware River watershed.
Land / Habitat Conservation Freshwater Conservation Water Resource Management

OWEB Operating Capacity Grants - Council Capacity

Oregon Watershed Enhancement Board (OWEB)
State/Local Government
Oregon
Unspecified amount
The OWEB Operating Capacity Grants support watershed councils and soil and water conservation districts in their operational costs. These biennial grants foster community engagement in voluntary watershed restoration efforts. By funding 45 districts, the program aids in conserving natural resources and enhances water quality through collaborative practices. The Council Capacity Grants specifically empower councils to restore native fish habitats and improve watershed functions, ensuring sustainable water management and healthier ecosystems.
Freshwater Conservation Water Resource Management Land / Habitat Conservation

OR Salmon and Trout Enhancement Program Mini-Grants

Oregon Department of Fish & Wildlife (ODFW)
State/Local Government
Oregon
Up to US $2,000
The OR Salmon and Trout Enhancement Program Mini-Grants, managed by the Oregon Department of Fish & Wildlife, offer up to $2,000 for projects that promote community engagement and volunteerism in fish habitat restoration, education, monitoring, fish culture, and research. To apply, contact your local STEP biologist and STAC member for guidance. The program aims to support initiatives that align with the goals of the STEP program while ensuring compliance with federal assistance regulations.
Fisheries Habitat & Ecosystem Restoration Ichthyology (Fish)

South Carolina Lowcountry Land Conservation Grant

Gaylord & Dorothy Donnelley Foundation
Private
Beaufort County, South Carolina, Berkeley County, South Carolina +7 more
US $10,000 - US $100,000
The Lowcountry Land Conservation Grant, offered by the Gaylord & Dorothy Donnelley Foundation, focuses on enhancing land conservation efforts in the Lowcountry region through a climate resiliency, diversity, equity, and inclusion lens. This grant supports non-profit organizations in their general operations and projects aimed at protecting natural and working lands, fostering collaboration among diverse communities, and advocating for sustainable policies. Eligible applicants must be 501(c)(3) organizations with a connection to land conservation.
Land / Habitat Conservation Environmental Justice & Advocacy Environmental Stewardship +1 more

15 and the Mahomies Foundation Grants

15 And The Mahomies Foundation
Private
United States
Up to US $15,000
The 15 and the Mahomies Foundation Grants aim to enhance the lives of children by supporting health, wellness, and community initiatives. This private foundation seeks to fund 501(c)(3) non-profit organizations, focusing on charitable causes. Grant requests are reviewed quarterly, and applicants must meet eligibility criteria. However, the foundation does not accept applications from individuals or for non-charitable items such as autographs or game tickets.
Children’s Health & Pediatrics Children’s Mental Health Children With Disabilities +4 more

Corporate Giving Program: Local Community Support

Cytokinetics
Association/Society
Alameda County, California, Bucks County, Pennsylvania +12 more
Up to US $20,000
Cytokinetics is dedicated to supporting local communities in the San Francisco Bay Area and Greater Philadelphia Region by providing access to essential services that address food and housing insecurity. Their funding initiatives aim to foster stability and resilience among at-risk populations, emphasizing charitable donations to qualified 501(c)(3) organizations that align with their corporate giving priorities. This support helps build strong connections between Cytokinetics and the communities they serve.
Food Security Equitable & Affordable Housing Supportive Housing & Shelters

Anthony F. Cordeiro Charitable Foundation Grant

Anthony F Cordeiro Charitable Foundation Incorporated
Private
Barnstable County, Massachusetts, Bristol County, Massachusetts +2 more
Up to US $5,000
The Anthony F. Cordeiro Charitable Foundation Grant aims to support nonprofit organizations in southeastern Massachusetts and Rhode Island that enhance the lives of families and children. Established in 2017, the foundation focuses on providing essential resources such as health services, mental health support, food, and shelter. Eligible applicants include 501(c)(3) organizations that align with the foundation's mission, ensuring no discrimination in hiring or service provision.
Family Services Basic Human Needs Health Care Access & Delivery +2 more

IN Recycling Market Development Program (RMDP)

Indiana Department of Environmental Management (IDEM)
State/Local Government
Indiana
US $50,000 - US $500,000
The Indiana Recycling Market Development Program (RMDP) aims to enhance recycling efforts by funding projects that promote waste reduction, reuse, and recycling. Established in the 1990s, it supports initiatives that increase recyclable material collection, lower municipal waste disposal, and improve community partnerships. Eligible applicants include businesses and local governments in Indiana, requiring a 50% cash match. The program excludes certain projects like waste-to-energy initiatives and construction costs, ensuring focused investment in sustainable waste management solutions.
Recycling Waste Management

ND: Environmental Quality Incentives Grant Program (EQIP)

USDA: Natural Resources Conservation Service of North Dakota
Federal Government
Bowman County, North Dakota, Golden Valley County, North Dakota +1 more
Unspecified amount
The Environmental Quality Incentives Program (EQIP) supports farmers and ranchers in North Dakota to implement conservation practices aimed at improving soil health, water quality, and wildlife habitats. Through financial and technical assistance, EQIP addresses critical natural resource concerns, including erosion, water conservation, and climate resilience. The Greater Sage Grouse Initiative emphasizes voluntary, incentive-based conservation efforts, enhancing the ecological landscape while promoting sustainable agricultural practices.
Habitat & Ecosystem Restoration Ornithological Conservation Land / Habitat Conservation +1 more

OEPA: Academic Institution Grant

Ohio Environmental Protection Agency
State/Local Government
Ohio
Up to US $300,000
The Ohio Environmental Protection Agency offers the Academic Institution Grant to support public and private K-12 schools, colleges, and universities in their recycling and education efforts. Funding is available for projects like recycling equipment, outreach programs, and civil engineering initiatives utilizing ground tire rubber. Applicants must meet matching fund requirements, with grant amounts ranging from $5,000 to $300,000, depending on the project category, and have specific timelines for project completion.
Waste Management Recycling

Shredder’s Studio Art Scholarship

Community Foundation for Nantucket
Private
Nantucket County, Massachusetts
US $1,000 - US $10,000
The Shredder’s Studio Art Scholarship is designed to assist Nantucket High School graduates pursuing degrees in fine arts or art therapy. This fund aims to cover college tuition costs, ensuring students have the support they need to excel in various artistic disciplines including painting, sculpture, photography, and graphic design. By investing in the artistic development of local talent, the scholarship fosters creativity and innovation within the community.
Fine Art Art Education Visual Arts +4 more

Volkswagen (VW) Environmental Mitigation Trust (CA)

California Air Resources Board
State/Local Government
California
Unspecified amount
The Volkswagen (VW) Environmental Mitigation Trust provides approximately $423 million to California for reducing excess nitrogen oxide (NOX) emissions from VW diesel vehicles. This initiative includes funding for various projects aimed at replacing older, polluting vehicles with cleaner alternatives, particularly in low-income communities. Key categories for funding include zero-emission buses, freight trucks, and marine projects, all aimed at improving air quality and public health.
Carbon / Greenhouse Gas Reduction Air Quality Electrification

Wildlife Health (Reptile and Amphibian) - Pilot Study Awards

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Up to US $20,000
The Morris Animal Foundation is offering Pilot Study Awards focused on reptile and amphibian health and welfare, particularly for chytrid research. These awards aim to fund innovative, proof-of-concept studies that demonstrate a clear understanding of animal health issues and collaboration with stakeholders. Proposals must have a direct impact on wildlife populations and adhere to strict health study policies. The maximum funding is $20,000 for a duration of 12 months, ensuring significant contributions to wildlife health advancements.
Herpetology Wildlife Health

Wildlife Health (Reptile and Amphibian) - First Award

Morris Animal Foundation
Private
Afghanistan, Algeria +166 more
Up to US $120,000
The Morris Animal Foundation invites research pre-proposals for the Wildlife Health (Reptile and Amphibian) - First Award, aimed at enhancing the health and welfare of amphibians and reptiles. This initiative focuses on impactful research, particularly in chytrid disease. Eligible applicants include early career researchers with appropriate qualifications and a clear understanding of animal health challenges. Projects should demonstrate collaboration with relevant stakeholders and provide direct benefits to wildlife populations, emphasizing conservation through an animal health perspective.
Herpetology Wildlife Health

Large Grants for Nonprofit Organizations Highlights

Large grants for nonprofit organizations provide significant funding to expand programs, enhance infrastructure, and scale operations. The following grants empower nonprofits to address large-scale challenges, foster sustainability, and create meaningful community impact.


Search Instrumentl's Large Grants for Nonprofit Organizations Database


Discover 8,000+ funding opportunities for nonprofits, with $3.43B available. Instrumentl connects nonprofits to tailored large-scale grants, offering tools for tracking deadlines, customized searches, and insights to achieve transformative growth.

Last updated: October 5, 2026. Next update: November 1, 2026.

Grant Insights : Large Grants for Nonprofit Organizations

Grant Availability

How common are grants in this category?

Quite common — grants in this category are more prevalent than in others.

8,000+ Large Grants for Nonprofit Organizations grants for nonprofits in the United States, from private foundations to corporations seeking to fund grants for nonprofits.

3,000+ Large Grants for Nonprofit Organizations over $25K in average grant size

3,000+ Large Grants for Nonprofit Organizations over $50K in average grant size

1,000+ Large Grants for Nonprofit Organizations supporting general operating expenses

7,000+ Large Grants for Nonprofit Organizations supporting programs / projects

3,000+ Grants on Instrumentl focused on Education

600+ Grants on Instrumentl focused on Food Access & Hunger

Grant Deadline Distribution

Over the past year, when are grant deadlines typically due for Large grants for Nonprofit Organizations?

Most grants are due in the first quarter.

Q1
29.8%
Q2
23.8%
Q3
23.9%
Q4
22.6%

Typical Funding Amounts

What's the typical grant amount funded for Large Grants for Nonprofit Organizations?

Grants are most commonly $34,887.

$0 $0 Min.
$34,887 $34.9 K Median
$655,609 $655.6 K Average
$188,250,000 $188.3 M Max.

Frequently asked questions

Nonprofits eligible for large grants typically have a proven track record of success and are ready to take on big projects with a lot of financial backing. Organizations with solid programs, strong financial management, and the ability to show long-term impact tend to receive these types of grants. Nonprofits working on large-scale initiatives in areas like healthcare, education, the environment, or economic growth are often prioritized. It’s important to show that your organization can handle the size of the project and funds required.

Based on Instrumentl’s live grant database for large grants, grant deadlines are most common in Q1, accounting for 29.8% of all submission dates. The slowest period for new grant opportunities in this category falls in Q4, making it a less competitive time for preparation and strategic planning.

Large grants exist to support projects that need significant financial resources. Funders want to invest in initiatives that lead to long-term impact, often focusing on areas like public health, education, climate action, and economic growth. The goal is to support projects that have the potential for wide reach, solve big problems, and continue making a difference long after initial funding runs out. Large grants focus on creating long-lasting, sustainable solutions.

Funding for large grants varies widely, with award amounts ranging from a minimum of $0 to a maximum of $188,250,000. Based on Instrumentl’s data, the median grant amount for this category is $34,887, while the average grant awarded is $655,609. Understanding these funding trends can help nonprofits set realistic expectations when applying.

Large grants are most commonly funded by government agencies, major foundations, and large corporate programs. Government agencies provide funding for public service projects in areas like healthcare, education, and infrastructure. Major foundations like the Bill & Melinda Gates Foundation and the Ford Foundation offer grants for projects focused on systemic change and social impact. Corporations also support large initiatives, especially those aligned with their corporate social responsibility (CSR) goals.

To improve the chances of receiving large grants, nonprofits should:

  • Create a detailed proposal – Make sure your proposal clearly outlines the project plan, timeline, and measurable results you expect to achieve.
  • Highlight past achievements – Give examples of how your organization has managed similar projects in the past and made a lasting difference.
  • Build partnerships – Collaborate with organizations or businesses that can help boost your project’s success and impact.
  • Have a clear long-term funding plan – Prove how you’ll sustain the project after initial grant funds run out, whether through partnerships, revenue, or other sources.

Need help writing a strong funding request? Follow our step-by-step guide to crafting compelling grant proposals.

Instrumentl simplifies the process of applying for large grants by offering an intuitive platform that helps nonprofits discover relevant funding opportunities, track deadlines, and analyze funder-giving patterns. The platform's automated alerts ensure users never miss a deadline, while detailed funder insights help organizations tailor their applications to align with grantor priorities.

See how Sleep in Heavenly Peace doubled their grant revenue from $1 million to $2 million within a year.