Best Large Grants for Nonprofit Organizations

The Fleishhacker Foundation offers Small Arts Grants to support small and mid-sized arts organizations in the Bay Area. These grants are designed for fiscally sponsored organizations, allowing them to access funding without traditional nonprofit status. Eligible applicants must meet specific budgetary requirements and demonstrate alignment with the foundation's mission. The program emphasizes support for historically marginalized artists and communities, ensuring that diverse artistic voices are represented in the cultural landscape.

The City of Suffolk's CDBG Program provides annual funding opportunities for non-profit organizations and city boards that serve local residents. Aimed at revitalizing neighborhoods and enhancing economic opportunities, the program prioritizes projects benefiting low- and moderate-income individuals. Eligible applicants must adhere to specific criteria, ensuring that funding supports community-focused initiatives. With a focus on collaboration, the program fosters partnerships to maximize impact and improve community facilities and services.

The 3-Year Tupper Postdoctoral Fellowship at the Smithsonian Tropical Research Institute offers a prestigious opportunity for researchers to conduct a three-year research program. Awarded annually, it provides a yearly stipend of $57,000 along with a research budget of up to $16,000. Eligible candidates must have completed their Ph.D. studies prior to the fellowship's commencement. This fellowship supports diverse research fields and fosters collaboration with experienced staff scientists at STRI.

The Arkansas Audubon Society Trust Grants support conservation, research, and education projects focused on Arkansas bird species and their habitats. Established in 1972, the trust offers grants ranging from $100 to $1200, prioritizing projects within the state but considering broader initiatives as well. Eligible applicants include individuals, students, educators, and nonprofits. Proposals are accepted biannually, with meetings held to discuss funding decisions, fostering a community dedicated to avian conservation.

The Institutional Challenge Grant aims to foster collaborative research by requiring institutions to adapt their policies and enhance capacities for meaningful partnerships. It encourages applications from diverse leadership teams in youth-serving areas, focusing on addressing inequalities in youth outcomes. The grant outlines four key goals: strengthening partnerships, pursuing a joint research agenda, facilitating institutional change, and enhancing collaborative capacities for producing actionable research evidence.

The Fred C. Gloeckner Foundation Research Fund, established in 2024 through a partnership with the American Floral Endowment (AFE), is dedicated to advancing floriculture research and education. With over 120 years of combined funding experience, it supports innovative projects across various fields related to floriculture. Grants are available for substantial research initiatives at U.S. universities and institutions, focusing on outcomes beneficial to the public, while ensuring projects are reviewed annually for renewal.

St. Mary's Bank Charitable Foundation Community Support Grants aim to enhance community welfare by providing financial support to nonprofit organizations. With a commitment to 'people helping people' since 1908, the foundation focuses on areas like youth programming, homelessness, and civic support. In 2023 alone, they donated over $200,000 to 190 organizations, reflecting their dedication to improving lives in New Hampshire. They prioritize funding for nonprofits within their service areas, ensuring impactful contributions to local communities.

The AHRQ Health Services Research Demonstration and Dissemination Grants (R18) aim to support innovative health services research that addresses priorities in quality, safety, and effective healthcare delivery. These grants encourage collaboration among various stakeholders, including patients and policymakers, to enhance healthcare practices across diverse settings. Applications are due by 5:00 PM local time of the applicant organization. This initiative fosters improvements in healthcare outcomes and delivery systems.

The AHRQ Health Services Research Projects (R01) aims to fund innovative health services research that aligns with AHRQ's priorities, such as enhancing healthcare quality and safety. This initiative encourages applications from various healthcare settings including hospitals and home care, promoting collaboration among diverse stakeholders like patients and policymakers. By addressing key areas of healthcare delivery improvement, this funding opportunity seeks to foster advancements in patient care and overall health system performance.

The Community Foundation of Greater Flint's CFGF: Community Impact Fund aims to support nonprofit organizations that provide vital resources to marginalized groups, fostering community connections and inclusivity. Established in 1988, this fund emphasizes collaborative efforts and strategic priorities aligned with community needs in Genesee County. Grants are available for various initiatives, including health, youth support, and historic preservation. Organizations must demonstrate a commitment to non-discrimination and relevance to local residents to qualify for funding.

The Paul & Helen Charitable Trust Grants focus on enhancing the lives of children and senior adults in Niagara and Erie Counties, NY, especially in the Black Rock/Riverside area. They support organizations providing essential services and promote public green space beautification. Grant amounts typically range from $10,000 to $25,000. Note that starting in 2026, requests will be considered every other year, emphasizing education programs, food insecurity, and respite care.

The AHRQ Small Health Services Research Grant Program (R03) invites applications for health services research focused on enhancing healthcare quality and patient safety. This funding opportunity supports diverse research settings, including hospitals and home healthcare. Projects may involve collaboration with various stakeholders such as patients, clinicians, and policymakers. By addressing AHRQ research priorities, this initiative aims to improve healthcare delivery and practice while promoting effective partnerships across the healthcare spectrum.

About

The Virginia Department of Housing and Community Development (DHCD) is committed to creating safe, affordable and prosperous communities to live, work and do business in Virginia. Find out more about DHCD, including locations, mission and about our director.

CDBG Project Grants

CDBG Project Grants are awarded competitively to aid eligible localities in implementing projects that will most directly impact the greatest needs of the community. There are four primary project types under this funding source: Housing Rehabilitation, Infrastructure, Economic Development, and Public Services.

Localities with potential projects that have activities applicable to more than one of these project types should contact DHCD for technical assistance

Kansas Housing Resources Corporation

Kansas Housing Resources Corporation (KHRC) is a self-supporting, nonprofit, public corporation that serves as the primary administrator of federal housing programs for the state of Kansas. KHRC delivers solutions to those who are working to end the housing crisis in Kansas. The corporation’s vision can only be achieved when all Kansans have the support and resources they need to achieve their goals, no matter where they are in their housing journey.

CSBG Discretionary Grant

Kansas Housing Resources Corporation (KHRC) establishes guidelines for the awarding of discretionary grants as authorized by the Kansas Community Services Block Grant (CSBG). The primary intended use of the grant funds awarded to Kansas and to subgrantees is “to provide assistance to local communities in Kansas, working through a network of Community Action Agencies and other neighborhood-based organizations, for the reduction of poverty, the revitalization of low-income communities, and the empowerment of low-income families and individuals in rural and urban areas to become fully self-sufficient.”

CSBG Purpose and Goals

• Promoting maximum participation of people and communities with low-income
• Leveraging resources of other anti-poverty programs
• Strengthening community capabilities for planning or coordinating resources for local needs and conditions of poverty
• Using innovative approaches to address causes and conditions of poverty
• Measuring impact to ensure accountability and ongoing data-driven quality improvement 

As outlined with the FFY 2025-2026 CSBG State Plan, this RFP seeks proposals for: 1) Innovative Programs/Activities or 2) Training/Technical Assistance

Applicants are advised that direct services funded by CSBG are restricted to Kansas residents. with household incomes that fall at or below 200 percent of the Federal Poverty Guidelines

Innovative Projects

For the purposes of this funding opportunity, proposals will be considered “innovative” if they:

• Support a project that is new to the agency and/or
• Support a modification to an existing project to make it more effective or efficient and/or
• Address an unmet need of the agency or community and/or
• Support a collaboration that addresses poverty in their communities.

Applicants should describe how the proposed project is an effective approach to ameliorate the causes and effects of poverty. Project descriptions should include the applicant’s plan to sustain the proposed project. CSBG programs often include addressing employment, education, income management, housing, nutrition, emergency services and/or health to combat the central causes of poverty.

The Hilles Fund Grant supports programs that serve vulnerable populations in Philadelphia and Vermont's Northeast Kingdom. With grants ranging from $4,000 to $10,000, it prioritizes initiatives that provide children, youth, and women with pathways to economic independence, including educational opportunities and social services. The fund also values advocacy efforts aligned with its mission and gives preference to organizations with operating budgets under $2 million.

The Windgate Charitable Trust Grant focuses on enhancing educational opportunities, health access, and community support in Arkansas. It aims to improve education through need-based scholarships and teacher preparation programs, enhance health with nursing programs and healthcare access, and strengthen community initiatives addressing food and housing insecurities. This grant is available to organizations with a history of funding from Windgate, as unsolicited inquiries are no longer accepted.

The Indiana Climate and Democracy Catalyst Fund aims to empower frontline organizations in Indiana by enhancing their capacity to address climate and democracy challenges. Supported by local, state, and national funders, the initiative focuses on community-driven outcomes and storytelling to inspire further funding. This strategic collaboration seeks to uplift BIPOC-led, LGBTQ+ serving, and rural organizations, fostering an inclusive environment for all Indiana residents to thrive while advocating for environmental justice.

The ALL RISE Mini-Grant Program, initiated by the Aaron Judge All Rise Foundation, empowers youth in Bronx, Fresno, and San Joaquin Counties. Established in 2019, it awards $3,000 grants to organizations fostering youth leadership, citizenship, mental well-being, and community involvement. Projects may include skill-building programs or school activities aimed at enhancing youth development and community engagement, ensuring that children and families receive essential support from various sectors.

The NAILBA Charitable Foundation Grant aims to support small, well-managed U.S. charities that assist those in need, particularly children. Grants are available to organizations with backing from a NAILBA member and that meet specific criteria, such as nonsectarian operation and appropriate fiscal accountability. Since its inception in 2002, the foundation has invested in community transformation by funding initiatives that directly engage in beneficial services, thereby enhancing the welfare of underprivileged groups.

The Louisiana Project Grants, managed by the Louisiana Division of the Arts, aim to enhance community engagement through diverse artistic initiatives. The program supports various art forms, including dance, music, and visual arts, focusing on innovation and collaboration. By prioritizing equity and inclusion, the grants foster artistic growth while ensuring access for all residents. Eligible applicants include nonprofit organizations and educational institutions within Louisiana, emphasizing projects that benefit the community and promote cultural diversity.

The Liberty Mutual Foundation, through the Safeco Insurance Fund, offers discretionary grants to support nonprofits in Washington State. Established in 2006, the fund focuses on empowering vulnerable communities by funding initiatives in education, youth workforce development, housing stability, and climate resiliency. Grants are available for both single and multi-year programs, with a continuous review process. Organizations must be located in Washington and adhere to eligibility criteria, including not having applied within the last 12 months.

The Honolulu Grants-In-Aid program aims to support services for economically and socially disadvantaged populations, focusing on public benefits in arts, culture, economic development, and the environment. Grants are available in two tiers, with amounts ranging from $5,000 to $150,000. The funds will be allocated to projects that enhance community well-being, promote cultural awareness, and support vulnerable groups, such as seniors and victims of domestic violence, thereby fostering sustainable improvements in quality of life.

The ECRAC Resiliency Grant for Arts Organizations provides funding of up to $600 for artists and organizations to support their projects affected by the pandemic and racial disparities. This grant is available until June 30, 2026, or until funds are depleted, and is open to past, current, or new grantees. Eligible projects can include various art forms such as performance, dance, photography, and more, as long as they comply with public health guidelines.

The Community Foundation of Marquette County is dedicated to funding impactful projects that empower local organizations to tackle community challenges. Eligible projects span various categories including education, environmental initiatives, and social services. With a maximum grant amount of $5,000, the foundation prioritizes innovative proposals that promote sustainable community development and collaboration among organizations. The foundation welcomes applications from both local and outside entities, provided they serve the Marquette County community.

The Sturgis Area Community Foundation (SACF) offers the Community Impact Grant to enhance the quality of life in St. Joseph County, Michigan. This grant supports nonprofit-led initiatives in key areas such as community development, housing, early learning, and educational attainment. Proposals must align with SACF's funding priorities and serve local residents. With a commitment to lasting impact, SACF builds permanent endowment funds to address future community needs.

Department of Fish and Game (DFG)

The Department of Fish and Game’s mission is to conserve the Commonwealth’s abundant marine and freshwater fisheries, wildlife, plants, and natural communities, as well as the habitats that support them, for the benefit and enjoyment of all people.

Massachusetts Community Biodiversity Grants

About the Opportunity

The Community Biodiversity Grants program supports local efforts to protect and restore biodiversity everywhere.

The Massachusetts Biodiversity Goals establish an ambitious, whole-of-government approach to rebuild biodiversity and invest in nature to sustain our health and well-being, food security, economy, and way of life. The plan sets four key goals—Protect, Restore, Sustain, and Connect—each with specific strategies for action for 2030, 2040, and 2050. 

The Community Biodiversity Grants program seeks proposals for projects that drive on-the-ground progress towards the Biodiversity Goals. The program will award grants between $20,000 and $150,000 to support biodiversity conservation and bring nature to every neighborhood.

The Impact100 Gulf Coast Grant empowers women to make a significant difference in their community by awarding large grants to qualifying organizations. Focus areas include arts, environment, health, education, and family initiatives that enhance lives in the Panhandle. Eligible applicants must be tax-exempt charities operating in specific Florida counties and adhere to grant guidelines. Funds must be fully expended within 24 months to ensure impactful community transformation.