Best Large Grants for Nonprofit Organizations in Texas

BOK Charitable Contributions aims to enhance community life and economic wellbeing across several states, focusing on four key pillars: United Way, economic development, education, and basic needs. The foundation supports organizations that address poverty, education, and community health. Their strategic approach ensures impactful contributions, and they welcome grant applications year-round. BOK Financial's commitment is evident in its partnerships with local nonprofits, fostering sustainable growth and development in the regions they serve.

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

The Global Impact Cash Grants by Cisco Systems Foundation support innovative early-stage solutions aimed at addressing significant social problems. Targeting nonprofit and nongovernmental organizations, these grants focus on four key sectors: crisis response, education, economic empowerment, and climate regeneration. Eligible organizations must demonstrate alignment with these areas, particularly serving underserved communities. The foundation seeks to leverage technology for impactful solutions, ensuring sustainability and community resilience through strategic investments.

State Farm's Good Neighbor Citizenship Company Grants aim to enhance community safety, development, and education. Focused on long-term impact, they support initiatives in auto and home safety, disaster preparedness, affordable housing, and educational programs. Eligible recipients include nonprofits, educational institutions, and government entities. However, funding is not available for individuals, religious programs, or organizations outside the U.S. By addressing critical community needs, these grants foster safer and more resilient neighborhoods.

The Hearst Foundation: Culture Grant aims to support outstanding nonprofits that enhance cultural engagement and artistic talent in the U.S. With a focus on programs that reach young people, the grant prioritizes organizations that create lasting impacts in the arts and sciences. The Foundation allocates 25% of its funding to cultural initiatives, favoring established organizations with a history of significant results. Eligible nonprofits must encourage inclusivity and sustainability in their programs.

The Hearst Foundation's Social Service Grant focuses on tackling chronic poverty by funding direct-service organizations that implement effective solutions for economic independence and family strengthening. With a mission to support diverse nonprofits in the U.S., the Foundation allocates approximately 15% of its total funding to social services, prioritizing scalable programs that serve significant populations. The minimum grant size is $100,000, and special consideration is given to organizations addressing affordable housing, domestic violence, and youth development.

The Meadows Foundation Grant Program is dedicated to enhancing the quality of life for Texans through diverse funding initiatives across education, environment, arts, and health. With a focus on community development and support for nonprofit organizations, the foundation aims to address pressing issues like homelessness and mental health. By prioritizing programs that offer measurable outcomes, they foster innovation and empower local efforts, ensuring a lasting impact in Texas. This grant program reflects a commitment to sustainable development and community well-being.

The Michael & Susan Dell Foundation provides grants to organizations focused on improving the lives of children in urban poverty in the U.S., India, and South Africa. They prioritize projects in education, health, and family economic stability. Grants typically do not exceed 25% of a project's budget or 10% of an organization's annual expenses. The foundation seeks to partner with organizations already making an impact, ensuring funding supports impactful social enterprises.

The Moody Foundation Grant supports charitable projects in Texas, focusing on innovative ideas that foster long-term community improvements. Eligible recipients include registered 501(c)(3) nonprofits, governmental entities, and certain supporting organizations. The Foundation prioritizes grants for education, health, arts, and social services, particularly in underserved areas like Galveston, Austin, and Dallas. Applicants should anticipate a twelve-month process from inquiry to funding decision, as the Foundation carefully reviews each proposal.

Roche Corporate Donations and Philanthropy (CDP) focuses on impactful projects that foster sustainable development, engage employees, and leverage Roche's expertise. Their philanthropic efforts prioritize humanitarian, educational, environmental, and cultural initiatives, aiming to build stronger communities and support innovative projects. Eligibility is limited to local organizations, while ineligible projects include those with political or religious ties. The foundation strives to create a positive societal impact through collaboration and strategic partnerships.

The Semnani Family Foundation, established in 1993, is dedicated to supporting marginalized communities worldwide through health, education, and disaster relief initiatives. Founded by Khosrow and Ghazaleh Semnani, it began by funding an orphanage in Romania. The foundation also operates locally, providing free healthcare through the Maliheh Free Clinic in Utah. Its commitment to human welfare drives impactful partnerships in countries such as Afghanistan, India, and South Africa, focusing on the most vulnerable populations.

The Sidney Stern Memorial Trust Grant supports charitable, scientific, medical, and educational organizations that are 501(c)(3) certified. This private funder emphasizes impactful service to diverse populations without discrimination. Grants must be utilized within the United States and cannot be awarded to individuals, political candidates, or lobbying efforts. The Trust is dedicated to enhancing the general welfare through soundly-managed initiatives that contribute significantly to community needs.

The Audacious Project Grant Program, supported by TED, aims to catalyze social impact by funding bold solutions to pressing global challenges. This initiative encourages changemakers to develop transformative ideas into actionable plans, with a focus on various issues, including health and education. The program operates on a rolling basis, welcoming applications from individuals and organizations with a proven track record and a budget of at least $2 million. Join us in creating lasting change for a better world.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

The Hoblitzelle Foundation Grant, established in 1942, supports nonprofit organizations in Texas, particularly in the Dallas area, with funding for capital projects such as construction and technology. The foundation prioritizes initiatives in arts, education, medical, and social services, investing over $252 million in various sectors. Eligible applicants must have a 501(c)(3) classification, and grants are not awarded for religious purposes or to individuals. This grant is a valuable resource for enhancing community impact.

The Corporate Giving Program by the Franklin P. and Arthur W. Perdue Foundation supports nonprofit organizations that enhance community welfare. Focus areas include agriculture, education, fighting hunger, and public safety. Eligible applicants must have IRS 501(c)(3) status and a Taxpayer Identification number. Requests are prioritized for programs directly benefiting communities near Perdue facilities across various states. The foundation emphasizes responsible stewardship and community engagement in all funding decisions.

The Waco Foundation offers Program/Operating Support Grants aimed at 501(c)(3) nonprofit organizations serving McLennan County, Texas. These grants support initiatives that address root causes of community challenges, focusing on equitable outcomes and enhancing local nonprofits' impact. Established in 1958, the foundation manages over $100 million in charitable assets and prioritizes projects that foster collaboration, improve quality of life, and support vulnerable populations. Interested organizations must submit a Letter of Inquiry to initiate the application process.

Insperity's Corporate Contributions program emphasizes community involvement and corporate citizenship, providing philanthropic grants and event sponsorships to 501(c)(3) nonprofit organizations. Eligible organizations must engage Insperity employees or contribute to the communities where they operate. The program aims to support nonprofits in achieving their service goals and enhancing community welfare. Applications must be submitted 90 days prior to events, and funding requests can be made once a year.

The R.F. and Jessie Shaw Foundation Grant, administered by the East Texas Communities Foundation, supports charities primarily in Rusk County, Texas, focusing on wellness, healthcare, and education. Established in memory of Dr. Shaw and Jessie Lewis, the grant aims to continue their legacy of community support. Applications are by invitation only, with the application link sent out on October 1, 2025, and the deadline for submissions is October 31, 2025, at 5:00 p.m.

J.B. Hunt Transport Services offers financial support for various community projects through its Company Giving program. Focused on four key areas—Health Care, Veterans' Support, Education, and Crisis Management—this initiative aims to enhance the well-being of local communities. Eligible applicants include 501(c)(3) organizations, schools, and civic groups, while organizations that primarily benefit their members or have high management overhead may be excluded. The program underscores J.B. Hunt's commitment to corporate social responsibility.

Ameriprise Community Grants focus on supporting nonprofits that enhance community vitality and meet basic needs. With over 120 years of commitment to philanthropy, Ameriprise Financial engages employees in volunteerism and grantmaking. Key giving areas include hunger relief, housing stability, and community development. Priority is given to organizations with active volunteer engagement from Ameriprise advisors and employees, creating a meaningful impact on financial independence and community resilience.

Mission

Baptist Health Foundation of San Antonio is committed to honoring God and our Baptist heritage by fostering and funding health initiatives in our community.

Grantmaking

Baptist Health Foundation of San Antonio provides grants to around 100 nonprofits each year, supporting a wide range of organizations, from community food pantries to churches and medical facilities. At BHFSA, we deeply value the opportunity to foster long-lasting relationships and grow our understanding of the challenges affecting the residents of our service area.

Responsive Grants

Baptist Health Foundation of San Antonio recognizes the many ways organizations are working to improve the quality of health in our community and understands such work must be supported financially to thrive. Responsive Grants provide funding of up to $300,000 for mid- to large-sized organizations.

Specific Grant Requirements

• The organization must have had at least $250,000 in actual revenue during the most recently completed fiscal year;
• The application amount must not exceed 25 percent of the organization’s total actual revenue in the most recently completed fiscal year;
• The application amount must fall in the range of $25,000-$300,000;
• The organization must not have received a Responsive Grant in the most recent grant year (Universities are exempt from this requirement);
• The organization must not have unspent grant funds from a previous Responsive Grant that supported a project; and
• The application must include projected quantifiable metrics that will be tracked during the grant period, which may include unduplicated number of individuals served, duplicated beneficial encounters, and expected outcomes (1 Overall Goal and 3 Objectives). This data contributes to the funding decision at the application stage, as well as the final report for grants that are awarded.

The O'Reilly Automotive Foundation Grant focuses on enhancing community welfare through philanthropic initiatives that support economic stability, workforce development, health services, and disaster relief. Established in 2020, the Foundation seeks to empower underrepresented individuals and organizations in the U.S. by addressing vital community needs. It particularly aims to provide assistance to nonprofits that foster positive change and improve quality of life for those in need, ensuring a lasting impact in local communities.

Impact San Antonio Grants empower nonprofit organizations in the region by providing funding for initiatives that focus on Arts & Culture, Education, Environment & Preservation, Family, and Health & Wellness. Since 2004, over $2.6 million has been awarded to impactful projects. Eligible applicants must be recognized 501(c)(3) organizations operating within designated Texas counties, ensuring a significant positive contribution to their communities.

The CNS Pantex Community Investment Grant Program, administered by the Amarillo Area Foundation, invites nonprofit organizations in the northern Texas Panhandle to apply for funding. This program prioritizes basic needs, education, health, and community development. Eligible applicants must possess 501(c)(3) status and serve local communities. The focus is on projects that address pressing community needs, fostering support for families, youth, and essential services. Proposals from outside the designated counties will not be accepted.

The Mutual of America Foundation Community Partnership Award honors exemplary nonprofit organizations in the U.S. that foster collaborative partnerships across sectors. Annually, a national competition showcases numerous organizations demonstrating impactful community partnerships. Six organizations receive recognition, including the Thomas J. Moran Award, which offers $100,000, and the Frances R. Hesselbein Award, granting $75,000. Since 1996, the award has acknowledged 262 partnerships, emphasizing Mutual of America's commitment to societal improvement through collaboration.

The AAF Discretionary Grant, offered by the Amarillo Area Foundation, aims to enrich lives by supporting nonprofit organizations since 1957. Grants are awarded 3-4 times a year, focusing on strategic areas such as education, healthcare, and economic opportunity. Eligible applicants include 501(c)(3) organizations serving the northernmost 26 counties of the Texas Panhandle. The Foundation encourages potential applicants to consult with their Grants Program Officer before submitting proposals.